发布求助
文献互助 智能选刊 最新文献

Nouvelle revue francaise d'hematologie最新文献

筛选
英文 中文
Tuberculosis associated haemophagocytic syndrome: two cases with a favourable outcome. 结核相关噬血细胞综合征:两例预后良好。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
I Quiquandon, I Plantier, P Y Hatron, O Chassaing, F Bauters, B Desablens, B Devulder
{"title":"Tuberculosis associated haemophagocytic syndrome: two cases with a favourable outcome.","authors":"I Quiquandon,&nbsp;I Plantier,&nbsp;P Y Hatron,&nbsp;O Chassaing,&nbsp;F Bauters,&nbsp;B Desablens,&nbsp;B Devulder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Haemophagocytic syndrome is a heterogenous disease characterized by disordered macrophage activation associated with viral, bacterial or parasitic infection. The few reports of haemophagocytosis occurring in the presence of mycobacterial infection show a high mortality rate and we present two further cases notable for their favourable issue. Rapidity of diagnosis and immediate treatment could explain the avoidance of a fatal outcome.</p>","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 2","pages":"149-52"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18647698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New insights into directed cell migration: characteristics and mechanisms. 定向细胞迁移的新见解:特征和机制。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
H Gruler
{"title":"New insights into directed cell migration: characteristics and mechanisms.","authors":"H Gruler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The present article describes how it is possible to elucidate the essential cellular machines controlling directed migration. Investigations are performed with cells like granulocytes, fibroblasts or neural crest cells and these cells are found to contain two independent types of machines, a steerer (controller without feedback) for the speed and an automatic controller (controller with feedback) for the angle of migration. The first intracellular signal is the distribution of membrane bound receptors occupied by kinesis stimulating molecules from the extracellular space. Motile force is produced by a linear motor supplied by the chemically amplified first intracellular signal (total number of occupied receptors). When properties of the cellular steering device are investigated, results show the angle of migration to be corrected by an automatic controller and an asymmetric distribution of occupied receptors to be the first intracellular signal for directed migration. Properties of the goal-seeking device are also investigated. As in many different types of technical machines, the cellular machinery operates in a cyclic manner which in the case of granulocytes a measuring cycle of 8 s and a response cycle of approximately 60 s. These cellular machines may be understood in terms of a self-ignition mechanism where the renewal of membrane bound receptors is the essential step.</p>","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 5","pages":"255-65"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19674837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hematopoietic progenitor cell expansion. 造血祖细胞扩增。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
J Reiffers, L Douay
{"title":"Hematopoietic progenitor cell expansion.","authors":"J Reiffers,&nbsp;L Douay","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 6","pages":"333"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19873339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improved detection of CD2 on formaldehyde-fixed non dehydrated cells. 改进了甲醛固定非脱水细胞对CD2的检测。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
C Cruz, L Suarez, R Rivero
{"title":"Improved detection of CD2 on formaldehyde-fixed non dehydrated cells.","authors":"C Cruz,&nbsp;L Suarez,&nbsp;R Rivero","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 6","pages":"385"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19873348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
De novo acute myeloid leukemia in patients with Crohn's disease. 克罗恩病患者新发急性髓系白血病。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
H Dombret, J P Marolleau
{"title":"De novo acute myeloid leukemia in patients with Crohn's disease.","authors":"H Dombret,&nbsp;J P Marolleau","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Crohn's disease (CD) has been occasionally reported to be associated with myelodysplastic syndromes (MDS) or acute myeloid leukaemia (AML). From October 1991 to June 1993, four AML patients with a previous history of CD but no history of MDS were referred to our institution. Three presented AML with a monoblastic proliferation (one AML4 and two AML5). Cytogenetic analysis revealed a normal karyotype in two patients, an inv(16) in another and a del(11)(q24-25) in the fourth. Interestingly, the three patients with AML4/AML5 had not received high doses of immunosuppressive agents, prior CD therapy ranging from 1 to 4 months sulfasalazine with additional azathioprine in one case.</p>","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 3","pages":"193-6"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18573034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Account of the Roussel-Diamant symposium]. [鲁塞尔-戴蒙德研讨会记录]。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
{"title":"[Account of the Roussel-Diamant symposium].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 3","pages":"211-3"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18573038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma interacts with mafosfamide toxicity to normal haematopoietic progenitor cells: impact on in vitro marrow purging. 血浆与甲基环磷酰胺对正常造血祖细胞的毒性相互作用:对体外骨髓清除的影响。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
M C Giarratana, N C Gorin, L Douay
{"title":"Plasma interacts with mafosfamide toxicity to normal haematopoietic progenitor cells: impact on in vitro marrow purging.","authors":"M C Giarratana,&nbsp;N C Gorin,&nbsp;L Douay","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bone marrow purging with cyclophosphamide derivatives in autologous bone marrow transplantation has demonstrated that the killing of leukemic cells and simultaneous preservation of normal progenitor cells depends on a number of parameters, in particular the haematocrit, nucleated cell concentration and nature of the cells. We have previously described a reliable experimental procedure for in vitro bone marrow treatment, based on individual adjustment of the drug dosage. The present study reveals an inhibitory action of plasma on the toxicity of mafosfamide to normal haematopoietic progenitor cells. In an initial series of 42 successive patients, determination of the CFU-GM lethal dose 95% (CFU-GM LD 95) showed this parameter to be inversely correlated to the nucleated cell concentration (NCC) (p < 0.001). Assuming the plasma content of the buffy coat cells (BC) to be higher in the less rich marrow samples, we then investigated the role of plasma in progenitor cell sensitivity to the drug. Results were as follows: (1) in the presence of 60% autologous or allogeneic plasma, CFU-GM LD 95 was increased by a factor of 2.18 +/- 0.35 or 1.98 +/- 0.23 respectively as compared to controls in a solution of 2% bovine serum albumin (p = 0.014), (2) this observation remained valid whatever the origin of the plasma and (3) the same was true whatever the nature of the cells, derived from normal donors or patients with haematological malignancies. These data suggest that plasma contains an inhibitor(s) of mafosfamide.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 2","pages":"125-30"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18647107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acquired circulating anticoagulant with anti-factor V activity in AIDS: first case report. 具有抗因子V活性的艾滋病获得性循环抗凝血药:1例报告。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
A Denis, C Baudeau, E Verdy, R Couderc, E Rondeau, J D Sraer
{"title":"Acquired circulating anticoagulant with anti-factor V activity in AIDS: first case report.","authors":"A Denis,&nbsp;C Baudeau,&nbsp;E Verdy,&nbsp;R Couderc,&nbsp;E Rondeau,&nbsp;J D Sraer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An acquired circulating anticoagulant with anti-factor V activity appeared in a 29 year old AIDS patient with widespread Kaposi's sarcoma following 21 days of fresh frozen plasma therapy for haemolytic and uraemic syndrome. Residual factor V activity was very low (< 5% of normal). However, the inhibitor was of low titre (0.5 Bethesda Units/ml), while antigenic factor V levels remained at 100%. Dot blotting with human factor V and polyvalent and specific immunoglobulin antisera showed the antibody to belong to the IgG class. Haemostatic tests in vitro were only partly corrected by addition of washed human platelets and despite transfusion of large amounts of platelets the patient died from massive pulmonary haemorrhage. This would appear to be the first documented case of an anti-factor V inhibitor occurring in an AIDS patient.</p>","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 2","pages":"165-9"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18647701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circulating endothelial markers and ischemic status in peripheral occlusive arterial disease. 外周动脉闭塞性疾病的循环内皮标志物和缺血状态。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
M Seigneur, M Boisseau, C Conri, B Lestage, J Amiral, J Constans
{"title":"Circulating endothelial markers and ischemic status in peripheral occlusive arterial disease.","authors":"M Seigneur,&nbsp;M Boisseau,&nbsp;C Conri,&nbsp;B Lestage,&nbsp;J Amiral,&nbsp;J Constans","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 34 patients with peripheral occlusive arterial disease, circulating levels of endothelial cell markers were compared with the ischemic status. Unlike tissue plasminogen activator and plasminogen activator inhibitor, plasma levels of thrombomodulin were closely related to both transcutaneous oxygen pressure (p = 0.01) and the graded clinical stages of disease (p = 0.02). Levels of von Willebrand factor were correlated only with the transcutaneous oxygen pressure (p = 0.04). Since thrombomodulin and von Willebrand factor constitute markers of endothelial cell damage, the extent of endothelial injury would appear to be determined by the ischemic status.</p>","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 2","pages":"171-3"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18647703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transformation of follicular lymphoma with both t(14;18) and t(8;22). t(14;18)和t(8;22)对滤泡性淋巴瘤的转化。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
H Bisiau, A Daudignon, F Le Baron, J P Pollet, C Preudhomme, P Duthilleul, C Bastard
{"title":"Transformation of follicular lymphoma with both t(14;18) and t(8;22).","authors":"H Bisiau,&nbsp;A Daudignon,&nbsp;F Le Baron,&nbsp;J P Pollet,&nbsp;C Preudhomme,&nbsp;P Duthilleul,&nbsp;C Bastard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The majority of low grade non-Hodgkin's follicular lymphoma undergo clinical progression to intermediate and high grade lymphoma, but the molecular mechanisms involved in this transformation are not yet well understood. In this article, we describe the case of a 66 year old man with follicular non-Hodgkin's lymphoma (NHL), in whom a centroblastic leukaemic transformation led to death in six months, despite a transient period of remission. At the time of transformation, cytogenetic analysis revealed the original coexistence of t(14;18)(q32;q21) and t(8;22)(q24;q11). These results were confirmed by fluorescent in situ hybridization, while molecular analysis showed a BCL2-JH rearrangement but failed to detect a c-myc rearrangement or any additional p53 mutation. Our observations would therefore suggest other mechanisms to be involved in the transformation of follicular NHL.</p>","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 4","pages":"241-4"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19868441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信