Nutrition and health最新文献

{"title":"Acute postoperative dietary intake in older adult hip fracture patients: An exploratory three-day weighed food diary observational study.","authors":"Helen Lloyd, Sarah Allison, Naomi Burn, Fatemeh Vida Zohoori, Cecile Jones, Vikki Whittaker, John Derek Franklin","doi":"10.1177/02601060261494308","DOIUrl":"https://doi.org/10.1177/02601060261494308","url":null,"abstract":"<p><p>BackgroundOlder adults recovering from hip fracture surgery are at risk from poor outcomes that can impede dietary intake, delay recovery and exacerbate comorbidities. Adequate nutrition is critical to recovery in this group, yet acute postoperative intake is poorly understood. Measuring resting energy expenditure (REE) can inform optimal nutritional strategies.AimsThe primary aim of this observational study was to explore whether acute dietary intake of older adult hip fracture patients met individual REE needs and secondary aims were to explore patterns between REE and hospital length of stay, comorbidity and postoperative complications.MethodsA weighed food diary was used from postoperative day zero to three inclusive. All meals served were weighed before and after service. Snacks and oral nutritional supplementation were recorded. The study was registered with ClinicalTrials.gov (NCT06451679).SummaryTwenty-one participants were recruited; complete data were available for fourteen. Only one participant (male) met REE requirements. Lower intake on postoperative day one was observed alongside a longer length of stay. Oral nutritional supplement compliance was 11.9%. Additionally, 62.0% of participants would not meet REE based on standard hospital meal provision. This study provides preliminary insights regarding the energy intake of older adult hip fracture patients during acute postoperative recovery. The patterns observed suggest frequent underachievement of energy needs and highlight potential focuses for targeted education to support early postoperative nutrition. Given the small sample size, these patterns should be interpreted with caution.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261494308"},"PeriodicalIF":1.4,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A critical analysis of Supplementary Nutrition Programme under the Scheduled Caste locality Anganwadi Centres in Telangana.","authors":"Parupally Anjaneyulu","doi":"10.1177/02601060261491791","DOIUrl":"https://doi.org/10.1177/02601060261491791","url":null,"abstract":"<p><p>BackgroundMalnutrition remains a major public health concern affecting children's growth and development, leading to stunting, underweight, and disease. The Supplementary Nutrition Programme (SNP) implemented through 35,353 Anganwadi Centres (AWCs) in Telangana aims to improve the nutritional status of pregnant women, lactating mothers and 7 months to 6 years aged children.AimTo assess the accessibility, quality, and implementation of SNP services in Scheduled Castes (SC) AWCs and identify the reasons for the high prevalence of severely underweight (SUW) children.MethodsA total of 42 SC AWCs were selected from four districts of Telangana. Data were collected during December 2018 using structured questionnaires administered to 462 beneficiaries, including 120 pregnant women; 174 mothers of children aged 7 months to 3 years and 168 mothers of children aged 3 to 6 years.SummaryMost of the beneficiaries belonged to SCs, few are from Backward Classes and Scheduled Tribes. The majority utilised Government hospitals for institutional deliveries and received benefits under the 'KCR Kit' scheme. Regarding the One Full Meal programme, most are satisfied with food items, but some reported delays in food supply. Regular distribution of Balamrutham and eggs was observed in most centres. Nearly half of the AWCs had a low percentage of SUW, and the highest prevalence was observed in Bhadradri district. The highest prevalence of SUW children is attributed to Anganwadi Teacher mishandling of supplementary food, intra-household sharing of food, poor accessibility, staff shortages, inexperienced AWTs and weak monitoring.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261491791"},"PeriodicalIF":1.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of food insecurity with gastrointestinal and hepatic conditions in U.S. adults: A population-based study.","authors":"John C Lin, Jason C Lin, Joy Zhao, Gabriela Gardner, Shivan J Mehta, Stephanie M Moleski, Andrew W DuPont","doi":"10.1177/02601060261495635","DOIUrl":"https://doi.org/10.1177/02601060261495635","url":null,"abstract":"<p><p>BackgroundFood insecurity affects 2.33 billion people worldwide and disproportionately impacts those with inflammatory bowel disease (IBD). However, population-level evidence linking food insecurity and gastrointestinal (GI) conditions remains limited.AimTo examine the association between food insecurity and GI conditions, including IBD, hepatitis, and GI cancers, among U.S. adults using national survey data.MethodsWe analyzed 2023-2024 National Health Interview Survey data from U.S. adults reporting food insecurity and GI conditions, including IBD, hepatitis, and GI cancers. Multivariable logistic regression assessed associations, adjusting for demographic and socioeconomic factors.SummaryAmong 57,860 adults, 14.1% of those with GI conditions reported food insecurity versus 8.8% without. Food insecurity was significantly associated with GI conditions (adjusted odds ratio (OR): 1.68; 95% CI: 1.44-1.97), particularly IBD (OR: 1.78; 95% CI: 1.42-2.23) and hepatitis (OR: 1.67; 95% CI: 1.33-2.09). Over half of food-insecure individuals with GI conditions (55.4%) lacked Supplemental Nutrition Assistance Program benefits; only 14.0% were up-to-date on colorectal cancer screening. Food insecurity is strongly linked to GI conditions, yet many lack assistance, indicating the importance of screening and interventions in GI care.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261495635"},"PeriodicalIF":1.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of intradermal purified protein derivative (PPD) and vitamin D3 in the treatment of non-genital cutaneous warts.","authors":"Ammarah Ghafoor, Muhammad Tayyab Awan, Abdul Ghafoor Awan","doi":"10.1177/02601060261494669","DOIUrl":"https://doi.org/10.1177/02601060261494669","url":null,"abstract":"<p><p>BackgroundViral warts are a common skin infection, usually on the hands, feet, or face of children and young adults, and are caused by the human papillomavirus (HPV) due to lower immune resistance. The common types seen in Pakistan are common warts, plantar warts, and flat warts, which cause pain or cosmetic concern among patients.AimsTo compare and evaluate the efficacy of intralesional purified protein derivative (PPD) and vitamin D3 in the management of viral non-genital cutaneous warts.MethodsA retrospective, comparative study was conducted at Nishtar Medical University Hospital, Multan, Pakistan from January to July 2023. A total of 266 patients with 1-10 viral warts were divided into two groups: Group I was given intralesional PPD (0.1 mL of 10 TU), and Group II was given intralesional vitamin D3 (0.5 mL of 600,000 IU), each given at 2-week intervals for a maximum of four doses.SummaryThe mean age of participants was 42.84 ± 13.29 years, with a male predominance (67.3%). Complete clearance of warts was significantly higher in the PPD group (85.7%) compared to the vitamin D3 group (71.4%; <i>P</i> = .005). Subgroup analysis revealed better outcomes with PPD in younger patients with multiple warts and specific anatomical locations (palmar, plantar, trunk), while vitamin D3 showed superior clearance for limb warts. Intralesional PPD demonstrated superior efficacy compared to vitamin D3 in the treatment of viral warts. Both therapies were safe and well-tolerated. This study provides direct comparative evidence of distinct immunological mechanisms, offering practical insights for the management of recalcitrant warts.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261494669"},"PeriodicalIF":1.4,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved outcomes and reduced costs: Exclusive human milk diet for very low birth weight infants at a single center.","authors":"Gabriella Mudekunye, Zoe Tullius, Cynthia A Guevara, Amanda Timmerman, Gyan Moorthy, Martin Lee, Sireesha Reddy, Sadhana Chheda","doi":"10.1177/02601060261492789","DOIUrl":"https://doi.org/10.1177/02601060261492789","url":null,"abstract":"<p><p>BackgroundVery low birth weight (VLBW, <1500 g) infants are at increased risk for necrotizing enterocolitis (NEC) and other morbidities. An exclusive human milk diet (EHMD) may reduce complications compared with bovine fortifier or formula, but its clinical and economic benefits remain debated.AimTo evaluate the impact of EHMD implementation on clinical outcomes and healthcare resource utilization in VLBW infants at a single center.MethodsThis retrospective cohort study included VLBW infants admitted to El Paso Children's Hospital from February 2012 to September 2019. The pre-EHMD group (2012-2014, n = 104) received preterm formula or bovine fortifier, while the EHMD group (2014-2019, n = 225) received mother's or donor human milk with human milk-based fortifier until 34 weeks postmenstrual age. Outcomes included NEC, parenteral nutrition (PN) and antibiotic days, central line use, blood transfusions, growth, and healthcare costs.SummaryDespite lower gestational age and birth weight, the EHMD group had significantly lower rates of NEC (12.5% vs. 4.9%) and surgical NEC (8.7% vs. 3.1%), as well as fewer PN, antibiotic, and central line days and fewer blood transfusions. Periventricular leukomalacia was also reduced (26.9% vs. 19.6%), while growth outcomes were comparable. Although EHMD had higher upfront costs, overall resource savings yielded a favorable cost-benefit ratio of 1.83. These findings support EHMD as a clinically effective and economically advantageous strategy for VLBW infants.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261492789"},"PeriodicalIF":1.4,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149112875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative analysis of effects of daily green tea consumption on non-motor symptoms among community-dwelling older patients with Parkinson's disease.","authors":"Harutoshi Sakakima, Toshiro Uchi, Kazuki Nakanishi, Yuki Kato-Eguchi, Teruki Matsuoka, Ryoma Matsuzaki, Shogo Kakimoto, Yoshitake Baba, Makoto Kobayashi, Takanobu Takihara","doi":"10.1177/02601060261493252","DOIUrl":"https://doi.org/10.1177/02601060261493252","url":null,"abstract":"<p><p>BackgroundNon-motor symptoms (NMS) are prominent features of advanced Parkinson's disease (PD) that contribute to disability severity and quality of life impairment. Polyphenols in green tea are known to offer several health benefits.AimWe examined the effects of daily green tea consumption on NMS in community-dwelling older individuals with PD.MethodsPatients were divided into three groups based on their daily green tea consumption: <0.5 L/day (<i>n</i> = 42), 0.5-1 L/day (<i>n</i> = 12), and >1 L/day (<i>n</i> = 24).SummaryPatients who consumed green tea daily required significantly fewer medications than those who did not consume green tea daily (<i>p</i> = 0.042). The proportion of patients with moderate and severe sleep disturbances assessed via the Movement Disorder Society-Unified Parkinson's Disease Rating Scale was significantly lower in the >1 L/day group (<i>p</i> = 0.029). Sleep disturbances and constipation correlated significantly with daily green tea consumption (<i>r</i> = -0.35, <i>p</i> = 0.002 and <i>r</i> = -0.28, <i>p</i> = 0.018, respectively). Logistic regression analysis adjusted for age, sex, and number of medications showed that normal and slight sleep disturbances and constipation were significantly associated with daily green tea consumption quantity (odds ratio [OR]: 0.57, 95% confidence interval [CI]: 0.39-0.83, <i>p</i> = 0.004 and OR: 0.71, 95% CI: 0.50-0.99, <i>p</i> = 0.043, respectively). Daily green tea consumption may correlate with reduced sleep disorders and constipation in older patients with PD. Our research generates a new hypothesis that warrants further clinical trials and prospective investigations.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261493252"},"PeriodicalIF":1.4,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149112872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Famine exposure in childhood and multimorbidity risk in older adults.","authors":"Qianwen Yang, Panpan He, Zhiwei Zhang, XiaoMing Liu, Xuejiao Zeng, Lipeng Jing","doi":"10.1177/02601060261489297","DOIUrl":"https://doi.org/10.1177/02601060261489297","url":null,"abstract":"<p><p>BackgroundPrevious research on multimorbidity focused on patterns, prevalence, and correlation and studies on famine have primarily focused on single diseases, with limited research on its effect on multimorbidity, especially in China.AimsOur study aimed to examine the association between famine exposure and the risk of multimorbidity through a cross-sectional survey in older adults.MethodsA total of 1580 community-dwelling older people were included in this study. Famine exposure was classified as nonexposed, toddlers exposed (1-3 years old exposed), preschool-age children exposed (4-6 years old exposed), school-age children exposed (7-13 years old exposed), adolescent exposed (14 to 19 years old exposed), adult exposed (20 years and older exposed). Multimorbidity was defined as \"the co-occurrence of at least two chronic conditions in the same individual\" based on the data of 39 common diseases. The associations were presented using adjusted odds ratio (aOR) with corresponding 95% confidence intervals (CI), and statistical significance was determined at <i>p</i> < 0.05.ResultsThe results indicated that famine exposure substantially elevated the risk of multimorbidity. Compared with the nonexposed group, the risks of Cardiometabolic and Complex/multisystem multimorbidity were increased in the preschool (OR: 2.03, 95%CI: 1.01, 4.08) and school-age exposed groups (OR: 2.27, 95%CI: 1.06, 4.88), respectively. Specifically, early-life exposure to Chinese famine was associated with an increased risk of developing high blood pressure (OR: 1.46, 95%CI: 1.00-2.11), chronic pulmonary diseases/asthma (OR: 1.78, 95%CI: 1.02-3.12), fractures (OR: 1.865, 95%CI:1.14, 3.04), and cataracts (OR: 2.26, 95%CI:1.22, 4.19) in older adults.SummaryIndividuals exposed to famine in early childhood, especially during preschool and school-age years, significantly increased their risk of multimorbidity in adulthood. These findings highlight the need for targeted health interventions and long-term disease prevention strategies for individuals who experienced early-life nutritional deprivation.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261489297"},"PeriodicalIF":1.4,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comprehensive review on osteoporosis in women and beneficial effects of antioxidants on osteoporosis: A systematic review.","authors":"Ritu Panchal, Divya Kumari, Priya Chaudhary, Pracheta Janmeda, Anand Prakash","doi":"10.1177/02601060261491806","DOIUrl":"https://doi.org/10.1177/02601060261491806","url":null,"abstract":"<p><p>BackgroundThe effects of lack of vitamin D, calcium, obesity, age, and endocrine factors, as well as lifestyle-related factors like physical activity, tobacco use, alcohol, cigarettes, or adverse effects of medications such as corticosteroids, result in osteoporosis.AimThe proposed study intends to assess the role of hormonal changes and other related factors in the development of osteoporosis in women, as well as to highlight possible prevention and treatment options, such as nutritional supplementation and antioxidant strategies.MethodsThe signs and symptoms of osteoporosis include decreased bone mass and bone microarchitecture deterioration, resulting in an increased fragility of bone and greater susceptibility to fractures. A reduction in estrogen in postmenopausal women increases the activity of osteoclasts, leading to an increase in bone resorption and progressive bone loss. During this process, two kinds of cells, osteoclasts and osteoblasts, which are rigorously coordinated by various cytokines and hormones, are balanced. The primary component is the superoxide radical, which is one of the highly reactive species that osteoblasts must replenish when osteoclasts create tiny holes. This study contains a brief outline of the awareness of the mechanism for the reversal of bone loss, gender-, physiological-, and age-related skeletal osteopenia resulting in osteoporosis, and the function of antioxidants in bone repair and in bone loss.SummaryThis review is the report of a systematic review on the pervasiveness of osteoporosis worldwide.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261491806"},"PeriodicalIF":1.4,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional crackers from tiger nut, unripe plantain, and sorghum flours improve vascular and sexual health in hypertensive rats.","authors":"Ayokunle Ademosun, Adekemi Olusola-Ajamu, Ganiyu Oboh, Adeniyi Adebayo","doi":"10.1177/02601060261492018","DOIUrl":"https://doi.org/10.1177/02601060261492018","url":null,"abstract":"<p><p>BackgroundHypertension, erectile dysfunction, and dyslipidemia are interrelated conditions strongly driven by poor dietary habits dominated by refined carbohydrate snacks and high-fat fast foods.AimThis study investigated the potential of functional crackers formulated from tiger nut, unripe plantain, and sorghum flours to ameliorate N-nitro-l-arginine methyl ester and high-fat diet-induced hypertension and erectile dysfunction in Wistar rats.MethodsComposite crackers were prepared in different proportions and evaluated for effects on blood pressure, sexual behavior, lipid profile, nitric oxide (NO) bioavailability, and key enzymes linked to vasodilation including angiotensin-1 converting enzyme (ACE), phosphodiesterase-5 (PDE-5), and arginase in the kidney, penile, and heart tissues.SummaryFunctional crackers, particularly the 50% tiger nut + 25% unripe plantain + 25% sorghum formulation, significantly lowered systolic and diastolic blood pressure, improved sexual performance, and corrected dyslipidemia. The functional crackers enhanced NO production and modulated ACE, PDE-5, and arginase. The functional crackers were also richer in polyphenols and potassium but lower in sodium than conventional crackers. These findings highlight composite functional crackers as a promising, food-based strategy for managing hypertension and erectile dysfunction.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261492018"},"PeriodicalIF":1.4,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of coenzyme Q10 supplementation on in vitro fertilization outcomes in infertile patients with polycystic ovary syndrome.","authors":"Latife Mutlu Özmen, Neriman İnanç, Ahmet Emin Mutlu, Aslı Gizem Çapar","doi":"10.1177/02601060261491431","DOIUrl":"https://doi.org/10.1177/02601060261491431","url":null,"abstract":"<p><p>BackgroundPolycystic ovary syndrome (PCOS) is a leading cause of anovulatory infertility, but evidence regarding coenzyme Q10 (CoQ10) supplementation remains limited and inconsistent.AimTo evaluate associations between pre-IVF CoQ10 supplementation and embryological and reproductive outcomes in women with PCOS.MethodsThis retrospective cohort included 154 women receiving CoQ10 (100 mg/day for four weeks before IVF; <i>n</i> = 75) or no CoQ10 (<i>n</i> = 79), as documented in medical records. Embryological and reproductive outcomes were compared, and logistic regression analyses adjusted for age and BMI.SummaryMedian age was 27 years (IQR, 24-30) in both groups. Body weight was higher with CoQ10 [74 (64-86) vs. 68 (60-80) kg; <i>p</i> = 0.029], whereas BMI did not differ. CoQ10 recipients had higher median MII oocyte counts [18 (12-22) vs. 12 (10-16)], and 2PN oocyte counts [15 (11-20) vs. 10 (8-13); both <i>p</i> < 0.001]. Both medians were 50.0% higher with CoQ10. Pregnancy occurrence was 56.0% versus 30.4% (OR = 2.92, 95% CI: 1.50-5.65), clinical pregnancy was 46.7% versus 16.5% (OR = 4.44, 95% CI: 2.10-9.39), and live birth was 30.7% versus 6.3% (OR = 6.55, 95% CI: 2.34-18.34). Absolute between-group differences were 25.6, 30.2, and 24.4 percentage points, respectively. After adjustment, CoQ10 remained associated with pregnancy occurrence (aOR = 3.01, 95% CI: 1.54-5.90), clinical pregnancy (aOR = 4.82, 95% CI: 2.24-10.36), and live birth (aOR = 6.86, 95% CI: 2.42-19.47; all <i>p</i> ≤ 0.001). Pre-IVF CoQ10 supplementation was associated with better embryological and reproductive outcomes in this cohort. Given the retrospective, non-randomized design, prospective randomized trials are required to confirm efficacy and mechanisms. Selection bias, confounding by indication, and residual confounding therefore cannot be excluded.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261491431"},"PeriodicalIF":1.4,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}