Wael Sh Basri, Razaz Waheeb Attar, Salem Albagmi, Daneah Alibrahim, Fahad Alanezi, Saud Asman Almutairi, Hoda M AboAlsamh, Ibrahim Tawfeeq Alsedrah, Wejdan M Arif, Abeer Abdullah Alsadhan, Duha Sami AlSanad, Wala Sultan Alsultan, Hafsa Alabdullateef, Miznah Hizam AlShammary, Amal Mubarak Bakhshwain, Afnan Fahd Almuhanna, Munerah Almulhem, Norah Alnaim, Amal Hassan Alhazmi
{"title":"Effectiveness of ChatGPT for educators professional development: An empirical study with medical faculty.","authors":"Wael Sh Basri, Razaz Waheeb Attar, Salem Albagmi, Daneah Alibrahim, Fahad Alanezi, Saud Asman Almutairi, Hoda M AboAlsamh, Ibrahim Tawfeeq Alsedrah, Wejdan M Arif, Abeer Abdullah Alsadhan, Duha Sami AlSanad, Wala Sultan Alsultan, Hafsa Alabdullateef, Miznah Hizam AlShammary, Amal Mubarak Bakhshwain, Afnan Fahd Almuhanna, Munerah Almulhem, Norah Alnaim, Amal Hassan Alhazmi","doi":"10.1177/02601060251315795","DOIUrl":"https://doi.org/10.1177/02601060251315795","url":null,"abstract":"<p><p>Study purposethis study aims to investigate the extent to which ChatGPT enhances medical educators' pedagogical practices, fosters reflective teaching, and contributes to their ongoing learning and growth.Methodsthis cross-sectional survey study assessed ChatGPT's efficacy in contributing to professional development among medical educators. Utilizing purposive and convenience sampling, a questionnaire was administered to 309 medical educators. Statistical analyses, including t-tests and ANOVA, were conducted to evaluate perceptions of ChatGPT's effectiveness, considering demographic factors and impairment types.Resultsresource recommendations received the highest mean score (4.08), while continuing education had the lowest (3.62). T-tests showed no significant gender differences (<i>p</i> > .05), while ANOVA indicated significant variances across job roles (<i>p</i> < .0001) and age groups (<i>p</i> < .0001). Lecturers consistently rated ChatGPT's support highest, followed by assistant professors and associate professors, with professors providing lower ratings.ConclusionChatGPT's efficacy in providing personalized feedback, resource recommendations, pedagogical guidance, and other forms of support. However, addressing challenges such as ethical considerations and ensuring accuracy remains imperative for its effective integration into educational contexts.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060251315795"},"PeriodicalIF":1.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is there a sex difference in response to FODMAP diet group education for IBS? A clinical practice service evaluation.","authors":"Yifan Xing, Lee Martin","doi":"10.1177/02601060251324235","DOIUrl":"https://doi.org/10.1177/02601060251324235","url":null,"abstract":"<p><p><b>Background:</b> While the low fermentable oligosaccharides, disaccharides, monosaccharides and polyols diet, low FODMAP diet (LFD) has demonstrated effectiveness in managing irritable bowel syndrome (IBS) symptoms, little is known about sex-specific responses to this dietary intervention. <b>Aim:</b> This study evaluates the role of sex differences in symptom improvement following a dietitian-led, group education session on the LFD for IBS patients. <b>Methods:</b> A total of 305 patients, including 249 with a diagnosis of IBS and 56 classified as having suspected IBS, were enrolled in this study (79.7% female). Patients attended two group education sessions on the LFD. Primary outcomes were measured using the IBS Symptom Severity Score (IBS-SSS) and the Global Symptom Question (GSQ). Secondary outcomes included stool frequency, stool consistency and individual symptoms assessed by the Gastrointestinal Symptom Rating Scale. Statistical analyses were performed to compare baseline and follow-up data within and between sexes. <b>Results:</b> Both male and female patients experienced significant reductions in IBS-SSS scores and improvements in GSQ satisfactory relief, stool frequency, stool consistency and individual gastrointestinal (GI) symptoms following the LFD (<i>p</i> < 0.05). There were no significant between-sex differences in the extent of symptom relief (<i>p</i> > 0.05). <b>Conclusion:</b> The study found no significant sex-based differences in symptom reduction or GI relief following the intervention. These findings suggest that, despite differing symptom profiles and IBS prevalence, both male and female patients achieve similar relief with the LFD group education.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060251324235"},"PeriodicalIF":1.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Domenico Azzolino, Ivan Baldassari, Simone Perna, Emma Caneva, Giulia Carla Immacolata Spolidoro, Matteo Cesari, Tiziano Lucchi
{"title":"Food allergies in older people: Protocol for a systematic review and meta-analysis.","authors":"Domenico Azzolino, Ivan Baldassari, Simone Perna, Emma Caneva, Giulia Carla Immacolata Spolidoro, Matteo Cesari, Tiziano Lucchi","doi":"10.1177/02601060251321561","DOIUrl":"https://doi.org/10.1177/02601060251321561","url":null,"abstract":"<p><p><b>Background:</b> Although the global prevalence of food allergies has been reported as increasing, its study is still largely confined to children and young adults. Nevertheless, several age-related factors (e.g., gastrointestinal changes, inflammation, and immunosenescence), responsible for the so-called 'anorexia of aging', may potentially mask, mediate, and/or enhance food allergies symptoms in older people. Although still neglected, the topic is critical for older persons who might be exposed to the risk of nutritional deficiencies and undernutrition if the primary and safest strategy for the food allergies management (i.e., allergen avoidance) is inappropriately conducted. <b>Aim:</b> To describe the protocol of a systematic review and meta-analysis aimed at estimating the prevalence of food allergies in older people. <b>Methods:</b> The literature search will consider multiple databases including PubMed/MEDLINE, Scopus, EMBASE, and Web of Science. Search dates will be from the inception. Studies reporting the prevalence of food allergies in individuals aged 60 years and older will be considered. Only English-language studies will be included. The Joanna Briggs Institute Critical Appraisal Checklists for Prevalence and Cohort Studies will be used to evaluate the quality of the included studies. The Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines will be followed in the reporting. This protocol is registered in PROSPERO (CRD42023445399). Given the expected clinical and methodological heterogeneity among the primary studies, meta-analyses will be performed using a random-effect model. <b>Results:</b> Not applicable. <b>Conclusions:</b> The present article describes the protocol of a systematic review and meta-analysis to estimate the prevalence of food allergies in older people.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060251321561"},"PeriodicalIF":1.9,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition and healthPub Date : 2025-03-01Epub Date: 2024-10-07DOI: 10.1177/02601060241282357
Marietou Khouma, Mamadou Diallo, Doudou Sow, Steve Allen, Babacar Faye
{"title":"Efficacy of prebiotic, probiotic, and synbiotics in improving growth in children under age five years in Africa: A protocol for a systematic review.","authors":"Marietou Khouma, Mamadou Diallo, Doudou Sow, Steve Allen, Babacar Faye","doi":"10.1177/02601060241282357","DOIUrl":"10.1177/02601060241282357","url":null,"abstract":"<p><p><b>Background:</b> Stunting is among the main obstacles to human development affecting millions of children worldwide, particularly in the sub-Saharan Africa region. Randomized clinical trials have shown the positive effects of prebiotics, probiotics, and synbiotics in improving growth in children and toddlers. However, although the global mobilization to tackle its challenges in their different aspects is visible, it remains to define effective large-scale up interventions and strategies to obtain long-lasting impacts. <b>Objective:</b> The objective of this review is to re-evaluate the efficacy of prebiotics, probiotics, and/or synbiotics on growth in children 0 to 5 years in Africa including recently published studies. <b>Methods:</b> Systematic search will be carried out in Pubmed, Science Direct, clinicaltrial.org, and Google Scholar. Both randomized and observational studies that assess the association between prebiotics, probiotics, and synbiotics, and health benefits and growth in children under 5 years of age will be included in the review. PRISMA-P (preferred reporting items for systematic review and meta-analysis protocols) will be used used for this protocol, and PRISMA will be used for the systematic review. The Cochrane Risk Assessment Tool will be used to assess the quality of eligible studies. If the compiled data are appropriate and sufficient enough, we will perform a meta-analysis using RevMan software. <b>Conclusion:</b> This review will provide up-to-date and reliable information on the efficacy of prebiotics, probiotics, and synbiotics on the growth of children under 5 years of age especially in developing countries. PROSPERO registration number CRD42022343138.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"23-29"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition and healthPub Date : 2025-03-01Epub Date: 2023-03-14DOI: 10.1177/02601060231163922
Büşra Demirer, Hülya Yardımcı
{"title":"Nutritional literacy levels of university academic and administrative staff: A cross-sectional study from Turkey.","authors":"Büşra Demirer, Hülya Yardımcı","doi":"10.1177/02601060231163922","DOIUrl":"10.1177/02601060231163922","url":null,"abstract":"<p><p>AimThis study aimed to evaluate the nutritional literacy levels of university academic and administrative staff.MethodsData were collected with a questionnaire including sociodemographic variables, some eating habits, and the Nutritional Literacy Assessment Tool of Adults. A total of 413 individuals, 211 women (51.1%) and 202 men (48.9%), aged 23-64 (mean: 37.41 ± 10.04 years), were included in the study. The data obtained were evaluated with the SPSS 25.0 statistical package program.ResultsIt was found that the nutritional literacy level of 18.15% of the participants is at the borderline, 81.85 are sufficient. Women's nutrition literacy scores are significantly higher than men's (<i>p</i> = 0.034). A significant relationship was found between nutritional literacy, socioeconomic status, and some eating habits (<i>p</i> < 0.05). The average daily water consumption of individuals with sufficient nutritional literacy is statistically significantly higher than those with borderline nutritional literacy (<i>p</i> < 0.001). It was determined that individuals with borderline nutritional literacy skipped meals more frequently (<i>p</i> < 0.05).ConclusionThe present study suggests that nutritional literacy may be effective in developing healthy eating behaviors. The study's results can guide the determination of methods that will improve nutritional literacy and increase awareness in the future.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"147-154"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9103570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition and healthPub Date : 2025-03-01Epub Date: 2023-03-20DOI: 10.1177/02601060231163365
Md Mehedi Hasan
{"title":"Sex difference and socioeconomic inequality of underweight, overweight and obesity among adult population in Bangladesh.","authors":"Md Mehedi Hasan","doi":"10.1177/02601060231163365","DOIUrl":"10.1177/02601060231163365","url":null,"abstract":"<p><p><b>Background:</b> Due to rapid socioeconomic development and epidemiological transition, socioeconomic inequality of underweight, overweight, and obesity are becoming a public health concern in Bangladesh. There is a need for country-specific evidence of nutrition inequalities in Bangladesh. <b>Aim:</b> The aim of the study was to measure socioeconomic inequality and decomposition analysis along with the sex differences in underweight, overweight, and obesity among the adult population. <b>Methods:</b> A secondary data analysis was performed in the Bangladesh Demographic and Health Survey (BDHS) 2017-18, a cross-sectional survey used a multi-stage cluster sampling technique. Sociodemographic variables including age, sex, education, socioeconomic status, marital status, and anthropometric data of height and weight were considered for analysis. Body mass index was used for defining underweight, overweight, and obesity. Concentration index (CI) and decomposition analysis were performed for underweight, overweight, and obesity. <b>Results:</b> The proportion of underweight was 15.0%, overweight (23.0%), and obese (5.0%). Underweight was higher in males, whereas overweight and obesity were higher in females. The CI of underweight was -0.121 (<i>p</i> < 0.001), indicating socioeconomic inequality concentrated on lowering socioeconomic status; living in rural areas contributed 14.2% to this inequality. The CI of overweight and obesity was 0.213 (<i>p</i> < 0.001) and 0.142 (<i>p</i> < 0.001), respectively, indicating that inequalities of overweight and obesity concentrated in higher socioeconomic status; urban residency contributed 14.1% and 18.0% to socioeconomic inequality of overweight and obesity. <b>Conclusion:</b> Underweight remains a significant problem for poor people in rural areas, but overweight and obesity were highly prevalent in the higher socioeconomic status of urban areas. Education level and young age group significantly contribute to the socioeconomic inequality of malnutrition. A more detailed epidemiological study is required to understand the causes of socioeconomic disparities of nutritional status in Bangladesh.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"155-163"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9139540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Postprandial glucose-lowering effects by sago (<i>Metroxylon sagu Rottb.</i>) resistant starch in spontaneously type 2 diabetes, Goto-Kakizaki rat.","authors":"Ezarul Faradianna Lokman, Sal Hazreen Bugam, Aina Shafiza Ibrahim, Nurleyna Yunus, Fazliana Mansor, Vimala Balasubramaniam, Khairul Mirza Mohamad, Rabizah Md Lazim, Awang Zulfikar Rizal Awang Seruji","doi":"10.1177/02601060231152060","DOIUrl":"10.1177/02601060231152060","url":null,"abstract":"<p><p><b>Introduction:</b> The beneficial effects of resistant starch (RS) consumption on health in terms of reducing postprandial hyperglycaemia are evident. However, the potential of local Sarawak sago RS in regulating glucose has not been extensively studied. <b>Objectives:</b> This study aims to identify glucose-lowering effects of Sarawak sago RS, namely native (RS2) and chemically modified (RS4). <b>Methodology:</b> An oral glucose tolerance test (OGTT) was performed before and after 1 month treatment with sago RS2 and RS4 in spontaneously type 2 diabetes (T2D), Goto-Kakizaki (GK) rat. The mechanisms involved were further explored by screening the <i>in vitro</i> inhibitory activities of α-glucosidase and dipeptidyl peptidase (DPP)-IV. Histopathology examination for pancreas, kidney and liver tissues was done in response to sago RS intake using haematoxylin and eosin (H&E) staining. <b>Results and discussion:</b> The incremental area under the curve (iAUC) for blood glucose in RS-treated groups was decreased and significant in RS2-treated group (<i>p</i> < 0.05). Improved iAUC for insulin and higher glucagon-like peptide (GLP-1) levels were observed in all RS-treated groups (<i>p</i> < 0.05). Both sago RS may have potential roles in regulating glucose via α- glucosidase and DPP-IV inhibitory activities by reducing intestinal glucose absorption. For histopathology, although insignificant, sago RS2 and RS4 attenuated lesion scores of pancreatic tissue whereas the liver and kidney tissues significantly showed lesser lesion scores compared to the control diabetic group suggesting the potential of RS in reducing cell degeneration. <b>Conclusion:</b> Findings of this study indicates that RS2 showed greater glucose-lowering effect when compared to RS4, thus the therapeutic potential in the T2D management should be further explored.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"101-110"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10848014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition and healthPub Date : 2025-03-01Epub Date: 2024-08-28DOI: 10.1177/02601060241274440
Jessica Riman, Karen M Keane, Kirsty M Hicks, Georgia Allen, Daniel J Peart
{"title":"What nutrition advice is freely available for gymnasts, coaches and parents on their member National Governing Body webpages?","authors":"Jessica Riman, Karen M Keane, Kirsty M Hicks, Georgia Allen, Daniel J Peart","doi":"10.1177/02601060241274440","DOIUrl":"10.1177/02601060241274440","url":null,"abstract":"<p><p>The purpose of this content analysis was to ascertain what nutrition advice or information is freely available on a global scale through each National Governing Body (NGB) webpage. In total, 52 NGBs and the International Federation of Gymnastics (FIG) were identified based on the FIG November 2022 world rankings for both male and female athletes in all disciplines. Concluding observations were that publicly available nutrition advice is limited across the global gymnastics platforms. Conflicting advice was also identified within some organisations surrounding the weighing of gymnasts for hydration purposes and some macronutrient discrepancies thus, potentially impacting the clarity of the message for the reader. Based on this content analysis recommendations for future practice include providing clarity and provision of tools to measure hydration, dietary recommendations should be clear and specific, and a more centralised approach to standardise advice and publicly available information.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"39-46"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does oral iron and folate supplementation during pregnancy protect against adverse birth outcomes and reduced neonatal and infant mortality in Africa: A protocol for a systematic review and meta-analysis?","authors":"Yibeltal Bekele, Claire Gallagher, Mehak Batra, Melissa Buultjens, Senem Eren, Bircan Erbas","doi":"10.1177/02601060241256200","DOIUrl":"10.1177/02601060241256200","url":null,"abstract":"<p><p><b>Background:</b> Globally, one-third of pregnant women are at risk of iron deficiency, particularly in the African region. While recent findings show that iron and folate supplementation can lower the risk of adverse birth outcomes and childhood mortality, our understanding of its impact in Africa remains incomplete due to insufficient evidence. This protocol outlines the systematic review steps to investigate the impact of oral iron and folate supplementation during pregnancy on adverse birth outcomes, neonatal mortality and infant mortality in Africa. <b>Methods and analysis:</b> MEDLINE, PsycINFO, Embase, Scopus, CINAHL, Web of Science, and Cochrane databases were searched for published articles. Google Scholar and Advanced Google Search were used for gray literature and nonindexed articles. Oral iron and/or folate supplementation during pregnancy is the primary exposure. The review will focus on adverse birth outcomes, neonatal mortality and infant mortality. Both Cochrane Effective Practice and Organization of Care and Newcastle-Ottawa Scale risk of bias assessment tools will be used. Meta-analysis will be conducted if design and data analysis methodologies permit. This systematic review and meta-analysis will provide up-to-date evidence about iron and folate supplementation's role in adverse birth outcomes, neonatal mortality and infant mortality in the African region. <b>Ethics and dissemination:</b> This review will provide insights that help policymakers, program planners, researchers, and public health practitioners interested in working in the region. <b>PROSPERO registration number:</b> CRD42023452588.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"15-22"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141081991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition and healthPub Date : 2025-03-01Epub Date: 2024-11-21DOI: 10.1177/02601060241299010
Manyata Srivastava, Annu Gulia, Ashish Datt Upadhyay, Kamalesh Kumar Patel, Mari Jeeva Sankar, Anju Sinha, Pradeep Kumar
{"title":"Impact of iron-folic acid supplementation on maternal and neonatal outcomes: A systematic review & meta-analysis.","authors":"Manyata Srivastava, Annu Gulia, Ashish Datt Upadhyay, Kamalesh Kumar Patel, Mari Jeeva Sankar, Anju Sinha, Pradeep Kumar","doi":"10.1177/02601060241299010","DOIUrl":"10.1177/02601060241299010","url":null,"abstract":"<p><p><b>Background & Aims:</b> Iron-folic acid (IFA) supplementation is widely recommended as both a preventive and therapeutic measure for pregnant women. Despite its widespread use, there is limited research exploring adherence to IFA supplementation during pregnancy and its impact on maternal and neonatal outcomes. This study aims to assess the effectiveness of IFA supplementation in improving pregnancy and neonatal outcomes. <b>Methods:</b> A comprehensive search on PubMed, Google Scholar, EMbase and Trip databases was conducted for relevant studies published up to May 31, 2024. Outcomes measured were preterm birth (PTB), low birth weight (LBW), neonatal mortality, perinatal mortality, small for gestational age (SGA) and stillbirth. Pooled risk ratios (RRs) with 95% confidence intervals (CIs), sensitivity analysis, publication bias, trial sequential analysis and quality assessment of the included studies were performed. <b>Results:</b> Eleven studies involving a total of 42,458 pregnant women who received IFA supplementation and 16,351 women who received folic acid (FA) alone or Control (no supplementation) were included. A significant reduction in overall neonatal mortality (RR = 0.73, 95% CI: 0.61-0.87) as well as in subgroup analyses (IFA vs. control and IFA vs. FA) was observed. However, a decrease in incidence of LBW was noted only in IFA vs. control group (RR = 0.79, 95% CI: 0.69-0.90). No significant association was found for overall LBW (RR = 0.48, 95% CI: 0.08-2.76), PTB (RR = 0.56, 95% CI: 0.09-3.50), perinatal mortality (RR = 0.85, 95% CI: 0.69-1.04), SGA (RR = 0.98, 95% CI: 0.86-1.12) and stillbirth (RR = 0.75, 95% CI: 0.48-1.16) when comparing to IFA vs. control and IFA vs. FA group. <b>Conclusions:</b> Our findings provide strong evidence supporting the effectiveness of IFA supplementation in reducing neonatal mortality and LBW among pregnant women, highlighting its importance in prenatal care.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"81-90"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}