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Postprandial glucose-lowering effects by sago (Metroxylon sagu Rottb.) resistant starch in spontaneously type 2 diabetes, Goto-Kakizaki rat. 西米(Metroxylon sagu Rottb.)抗性淀粉对自发性 2 型糖尿病后藤柿崎大鼠的餐后降糖作用。
IF 1.9
Nutrition and health Pub Date : 2025-03-01 Epub Date: 2023-02-08 DOI: 10.1177/02601060231152060
Ezarul Faradianna Lokman, Sal Hazreen Bugam, Aina Shafiza Ibrahim, Nurleyna Yunus, Fazliana Mansor, Vimala Balasubramaniam, Khairul Mirza Mohamad, Rabizah Md Lazim, Awang Zulfikar Rizal Awang Seruji
{"title":"Postprandial glucose-lowering effects by sago (<i>Metroxylon sagu Rottb.</i>) resistant starch in spontaneously type 2 diabetes, Goto-Kakizaki rat.","authors":"Ezarul Faradianna Lokman, Sal Hazreen Bugam, Aina Shafiza Ibrahim, Nurleyna Yunus, Fazliana Mansor, Vimala Balasubramaniam, Khairul Mirza Mohamad, Rabizah Md Lazim, Awang Zulfikar Rizal Awang Seruji","doi":"10.1177/02601060231152060","DOIUrl":"10.1177/02601060231152060","url":null,"abstract":"<p><p><b>Introduction:</b> The beneficial effects of resistant starch (RS) consumption on health in terms of reducing postprandial hyperglycaemia are evident. However, the potential of local Sarawak sago RS in regulating glucose has not been extensively studied. <b>Objectives:</b> This study aims to identify glucose-lowering effects of Sarawak sago RS, namely native (RS2) and chemically modified (RS4). <b>Methodology:</b> An oral glucose tolerance test (OGTT) was performed before and after 1 month treatment with sago RS2 and RS4 in spontaneously type 2 diabetes (T2D), Goto-Kakizaki (GK) rat. The mechanisms involved were further explored by screening the <i>in vitro</i> inhibitory activities of α-glucosidase and dipeptidyl peptidase (DPP)-IV. Histopathology examination for pancreas, kidney and liver tissues was done in response to sago RS intake using haematoxylin and eosin (H&E) staining. <b>Results and discussion:</b> The incremental area under the curve (iAUC) for blood glucose in RS-treated groups was decreased and significant in RS2-treated group (<i>p</i> < 0.05). Improved iAUC for insulin and higher glucagon-like peptide (GLP-1) levels were observed in all RS-treated groups (<i>p</i> < 0.05). Both sago RS may have potential roles in regulating glucose via α- glucosidase and DPP-IV inhibitory activities by reducing intestinal glucose absorption. For histopathology, although insignificant, sago RS2 and RS4 attenuated lesion scores of pancreatic tissue whereas the liver and kidney tissues significantly showed lesser lesion scores compared to the control diabetic group suggesting the potential of RS in reducing cell degeneration. <b>Conclusion:</b> Findings of this study indicates that RS2 showed greater glucose-lowering effect when compared to RS4, thus the therapeutic potential in the T2D management should be further explored.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"101-110"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10848014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What nutrition advice is freely available for gymnasts, coaches and parents on their member National Governing Body webpages? 体操运动员、教练员和家长可在其国家管理机构成员的网页上免费获得哪些营养建议?
IF 1.9
Nutrition and health Pub Date : 2025-03-01 Epub Date: 2024-08-28 DOI: 10.1177/02601060241274440
Jessica Riman, Karen M Keane, Kirsty M Hicks, Georgia Allen, Daniel J Peart
{"title":"What nutrition advice is freely available for gymnasts, coaches and parents on their member National Governing Body webpages?","authors":"Jessica Riman, Karen M Keane, Kirsty M Hicks, Georgia Allen, Daniel J Peart","doi":"10.1177/02601060241274440","DOIUrl":"10.1177/02601060241274440","url":null,"abstract":"<p><p>The purpose of this content analysis was to ascertain what nutrition advice or information is freely available on a global scale through each National Governing Body (NGB) webpage. In total, 52 NGBs and the International Federation of Gymnastics (FIG) were identified based on the FIG November 2022 world rankings for both male and female athletes in all disciplines. Concluding observations were that publicly available nutrition advice is limited across the global gymnastics platforms. Conflicting advice was also identified within some organisations surrounding the weighing of gymnasts for hydration purposes and some macronutrient discrepancies thus, potentially impacting the clarity of the message for the reader. Based on this content analysis recommendations for future practice include providing clarity and provision of tools to measure hydration, dietary recommendations should be clear and specific, and a more centralised approach to standardise advice and publicly available information.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"39-46"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of celiac disease and its related factors in children aged 2-6 years old: A case-control study. 2-6岁儿童乳糜泻患病率及其相关因素:一项病例对照研究
IF 1.9
Nutrition and health Pub Date : 2025-03-01 Epub Date: 2023-04-02 DOI: 10.1177/02601060231167456
Mohsen Maleki, Farzaneh MontazeriFar, Abolfazl Payandeh, Zahra Azadbakht
{"title":"Prevalence of celiac disease and its related factors in children aged 2-6 years old: A case-control study.","authors":"Mohsen Maleki, Farzaneh MontazeriFar, Abolfazl Payandeh, Zahra Azadbakht","doi":"10.1177/02601060231167456","DOIUrl":"10.1177/02601060231167456","url":null,"abstract":"<p><p><b>Background:</b> Celiac disease (CD) is an immune-genetic disorder associated with the small intestine. <b>Aim:</b> The aim of this study was to determine the prevalence of CD and its related factors in children aged 2-6 years in southeastern Iran. <b>Methods:</b> In the present case-control research, the study groups were selected by convenience sampling method in Zahedan city, Sistan-and-Baluchestan province, southeastern Iran, from January 2021 till January 2022. Social-demographic status and personal information about the child, family, as well as the feeding pattern of children and mothers in the first six months of breastfeeding were examined. Frequency Food Questionnaire (FFQ) was also used for data collection. <b>Results:</b> The prevalence of CD was estimated at 9.2 per 10,000. Our findings showed that child age, birth weight, location of living, child birth type, child digestive disease, and child FFQ score played a significant role in the development of CD (<i>p</i> < 0.05). Children with CD consumed less bread and cereals, meat, eggs and legumes, dairy products, and fruits and vegetables (<i>p</i> = 0.004). In the first six months of breastfeeding, the mean intake of mothers with celiac children and mothers with healthy children was almost the same (<i>p</i> = 0.75). <b>Conclusion:</b> Nutrition in the first six months of lactation, gastrointestinal diseases, birth weight, and type of delivery played a significant role in causing CD in children aged 2-6 years, but mothers' diets in the first six months of lactation had no significant effect on CD incidence in their infants.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"247-254"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9234288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Weight gain, poor mental health and increased sedentary hours among Malaysian adults during the COVID-19 pandemic. 在2019冠状病毒病大流行期间,马来西亚成年人体重增加、心理健康状况不佳以及久坐时间增加。
IF 1.9
Nutrition and health Pub Date : 2025-03-01 Epub Date: 2023-03-20 DOI: 10.1177/02601060231164434
Guo Fu Ng, Shi-Hui Cheng
{"title":"Weight gain, poor mental health and increased sedentary hours among Malaysian adults during the COVID-19 pandemic.","authors":"Guo Fu Ng, Shi-Hui Cheng","doi":"10.1177/02601060231164434","DOIUrl":"10.1177/02601060231164434","url":null,"abstract":"<p><p>BackgroundThe Movement Control Orders (MCO) in Malaysia due to the COVID-19 pandemic had a profound impact on the lifestyle behaviours, weight changes, and mental health of the population.AimTo determine the changes in physical activity, sedentary behaviour, body weight status and mental health status among Malaysian adults before and during the pandemic.MethodsA total of 338 Malaysian adults participated in this cross-sectional online study. Sociodemographic and anthropometric data were self-reported. Physical activity and sedentary behaviour were assessed using International Physical Activity Questionnaire-Short Form (IPAQ-SF) while the Perceived Stress Scale (PSS-10), Patient Health Questionnaire (PHQ-9) and Generalised Anxiety Disorder Assessment (GAD-7) were used to examine stress, depression and anxiety, respectively. All statistical analysis was performed using SPSS version 28.0.ResultsThe results showed an average weight gain of 0.6 kg among the participants with 45.5% of them experiencing weight gain. In addition, sedentary behaviour (<i>p</i> < 0.001), PSS-10 score (<i>p</i> < 0.001), PHQ-9 score (<i>p</i> = 0.002) and GAD-7 score (<i>p</i> = 0.001) were significantly increased during the COVID-19 pandemic whereas the level of physical activity was significantly decreased (<i>p</i> = 0.003) during the pandemic. Weight changes during the pandemic were found to be associated with age, sedentary hours, and PHQ-9 score. Through binary logistic regression, sedentary hours (AOR = 1.068, 95% CI = 1.002-1.139, <i>p</i> = 0.043) were identified to be a risk factor for weight gain during the pandemic.ConclusionThe findings suggested that public health interventions to prevent weight gain should focus on strategies to increase physical activity for sedentary lifestyles.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"187-196"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9149864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding the relationship between WASH and malnutrition: Analysis of anthropometric data of children attending WASH-supported schools in Ogun State, Nigeria. 了解讲卫生运动与营养不良之间的关系:对尼日利亚奥贡州讲卫生运动支持的学校中儿童的人体测量数据进行分析。
IF 1.9
Nutrition and health Pub Date : 2025-03-01 Epub Date: 2023-04-24 DOI: 10.1177/02601060231168007
Hammed Oladeji Mogaji, Oladunni Nimota Adekunle, Olaitan Olamide Omitola, Clement Ameh Yaro, Ayodele Samuel Babalola, Simon Nnayere Odoemene, Dorcas Olufunke Adeaga, Taiwo Oluwakemi Adubi, Uwem Friday Ekpo
{"title":"Understanding the relationship between WASH and malnutrition: Analysis of anthropometric data of children attending WASH-supported schools in Ogun State, Nigeria.","authors":"Hammed Oladeji Mogaji, Oladunni Nimota Adekunle, Olaitan Olamide Omitola, Clement Ameh Yaro, Ayodele Samuel Babalola, Simon Nnayere Odoemene, Dorcas Olufunke Adeaga, Taiwo Oluwakemi Adubi, Uwem Friday Ekpo","doi":"10.1177/02601060231168007","DOIUrl":"10.1177/02601060231168007","url":null,"abstract":"<p><p>BackgroundThere has been a growing interest in better understanding the association between water, sanitation, and hygiene (WASH) and malnutrition.AimWe analysed anthropometric data of children attending WASH intervention schools and those from non-intervention schools in Ogun State, Nigeria.MethodsA total of 353 children across six schools (three interventions and three non-interventions) participated in this study. WASH conditions were assessed using WHO standardized tools and anthropometric data of children were analysed in WHO AnthroPlus and R Software.ResultsThe prevalence of stunting was 26.2% in the intervention group, and 29.4% in the control group (<i>p</i> = 0.045). Underweight was lower in the intervention group (3.9% vs. 10.1%) (<i>p</i> = 0.45). However, wasting was higher in the intervention group (32.3% vs. 8.2%) (<i>p</i> = 0.001). Of the variables included in our multivariate model (age, gender, and school category, i.e. intervention/control and class grade), only age was selected, and negatively associated with underweight, stunting and wasting (<i>p</i> = 0.000).ConclusionRegardless of WASH programming status, nutritional outcomes were significantly influenced by age of the children. Children are more likely to have lower <i>z</i>-scores as they grow older.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"255-262"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9423103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of iron-folic acid supplementation on maternal and neonatal outcomes: A systematic review & meta-analysis. 补充铁-叶酸对产妇和新生儿预后的影响:系统回顾与荟萃分析。
IF 1.9
Nutrition and health Pub Date : 2025-03-01 Epub Date: 2024-11-21 DOI: 10.1177/02601060241299010
Manyata Srivastava, Annu Gulia, Ashish Datt Upadhyay, Kamalesh Kumar Patel, Mari Jeeva Sankar, Anju Sinha, Pradeep Kumar
{"title":"Impact of iron-folic acid supplementation on maternal and neonatal outcomes: A systematic review & meta-analysis.","authors":"Manyata Srivastava, Annu Gulia, Ashish Datt Upadhyay, Kamalesh Kumar Patel, Mari Jeeva Sankar, Anju Sinha, Pradeep Kumar","doi":"10.1177/02601060241299010","DOIUrl":"10.1177/02601060241299010","url":null,"abstract":"<p><p><b>Background & Aims:</b> Iron-folic acid (IFA) supplementation is widely recommended as both a preventive and therapeutic measure for pregnant women. Despite its widespread use, there is limited research exploring adherence to IFA supplementation during pregnancy and its impact on maternal and neonatal outcomes. This study aims to assess the effectiveness of IFA supplementation in improving pregnancy and neonatal outcomes. <b>Methods:</b> A comprehensive search on PubMed, Google Scholar, EMbase and Trip databases was conducted for relevant studies published up to May 31, 2024. Outcomes measured were preterm birth (PTB), low birth weight (LBW), neonatal mortality, perinatal mortality, small for gestational age (SGA) and stillbirth. Pooled risk ratios (RRs) with 95% confidence intervals (CIs), sensitivity analysis, publication bias, trial sequential analysis and quality assessment of the included studies were performed. <b>Results:</b> Eleven studies involving a total of 42,458 pregnant women who received IFA supplementation and 16,351 women who received folic acid (FA) alone or Control (no supplementation) were included. A significant reduction in overall neonatal mortality (RR = 0.73, 95% CI: 0.61-0.87) as well as in subgroup analyses (IFA vs. control and IFA vs. FA) was observed. However, a decrease in incidence of LBW was noted only in IFA vs. control group (RR = 0.79, 95% CI: 0.69-0.90). No significant association was found for overall LBW (RR = 0.48, 95% CI: 0.08-2.76), PTB (RR = 0.56, 95% CI: 0.09-3.50), perinatal mortality (RR = 0.85, 95% CI: 0.69-1.04), SGA (RR = 0.98, 95% CI: 0.86-1.12) and stillbirth (RR = 0.75, 95% CI: 0.48-1.16) when comparing to IFA vs. control and IFA vs. FA group. <b>Conclusions:</b> Our findings provide strong evidence supporting the effectiveness of IFA supplementation in reducing neonatal mortality and LBW among pregnant women, highlighting its importance in prenatal care.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"81-90"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of malnutrition and main-meal- and snack-predominant intake among female adolescent students in boarding schools in Tasikmalaya, Indonesia. 印度尼西亚Tasikmalaya寄宿学校女青少年学生营养不良与以正餐和零食为主的摄入的关系。
IF 1.9
Nutrition and health Pub Date : 2025-03-01 Epub Date: 2023-03-27 DOI: 10.1177/02601060231166224
Lilik Hidayanti, Mohammad Zen Rahfiludin, Sri Achadi Nugraheni, Retno Murwani
{"title":"Association of malnutrition and main-meal- and snack-predominant intake among female adolescent students in boarding schools in Tasikmalaya, Indonesia.","authors":"Lilik Hidayanti, Mohammad Zen Rahfiludin, Sri Achadi Nugraheni, Retno Murwani","doi":"10.1177/02601060231166224","DOIUrl":"10.1177/02601060231166224","url":null,"abstract":"<p><p><b>Background:</b> Balanced dietary intake is needed to prevent malnutrition which is one of the nutritional problems faced by adolescents. <b>Aim:</b> To study the association between predominant dietary intake and nutritional status of female adolescent students in boarding schools in Tasikmalaya, Indonesia. <b>Method:</b> This cross-sectional study was conducted on 323 female adolescent students residing full-time in eight boarding schools in Tasikmalaya, West Java. Students' dietary intake was measured using the 3-non-consecutive-day 24-h recall method. The association between the predominant dietary intake and nutritional status was evaluated using binary logistic regression. <b>Results:</b> Of the 323 students, 59 (18.3%) were overweight/obese (OW/OB) and 102 (31.6%) had stunted growth. The predominant dietary intake in the OW/OB group was snacks, whereas, in the stunted group, it was main meals. Snack-predominant dietary intake was a risk factor for overweight and obesity (<i>p</i>  =  0.008; adjusted odds ratio [AOR]: 2.276; 95% confidence interval [CI]: 1.244-4.164), but it was a protective factor against stunting (<i>p</i>  =  0.008; AOR: 0.521; 95% CI: 0.322-0.842). <b>Conclusion:</b> The predominance of main meals and snacks as components of total dietary intake affected the nutritional status of female adolescent students living in boarding schools. Therefore, the dietary intake interventions should tailor and design the nutritional contents of main meals and snacks according to the nutritional status of the targeted individuals.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"235-246"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9561650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of dietary patterns on maternal anaemia in North Shewa, Ethiopia: A case-control study with Propensity Score Analysis. 饮食模式对埃塞俄比亚北谢瓦地区孕产妇贫血症的影响:利用倾向得分分析法进行的病例对照研究。
IF 1.9
Nutrition and health Pub Date : 2025-03-01 Epub Date: 2023-01-23 DOI: 10.1177/02601060231152345
Kelemu Tilahun Kibret, Catherine Chojenta, Ellie D'Arcy, Deborah Loxton
{"title":"The effect of dietary patterns on maternal anaemia in North Shewa, Ethiopia: A case-control study with Propensity Score Analysis.","authors":"Kelemu Tilahun Kibret, Catherine Chojenta, Ellie D'Arcy, Deborah Loxton","doi":"10.1177/02601060231152345","DOIUrl":"10.1177/02601060231152345","url":null,"abstract":"<p><p>ObjectiveThis study aimed to assess the effect of dietary patterns during pregnancy on anaemia.Design, Setting and ParticipantsA case-control study with propensity score analysis was conducted among pregnant women selected from five health facilities in North Shewa Zone, Ethiopia from November 2018 to March 2019. A multivariable conditional logistic regression model was applied after propensity score matching to assess the effect of dietary patterns on anaemia, and a <i>p</i> < 0.05 was taken as significant. Four hundred and seventeen pregnant women were included (105 cases and 312 controls) with a 1:3 case-to-control ratio. Cases were pregnant women with a haemoglobin level <11 gram/Deci litter (g/dL), and controls were pregnant women with a haemoglobin level ≥11.0 g/dL.ResultsA low dietary diversity score (adjusted odd ratio (AOR) = 2.14; 95% confidence interval (CI): 1.24, 3.69), reducing food intake (AOR = 6.89; 95% CI: 3.23, 14.70) and having no formal education (AOR = 3.13; 95% CI: 1.18, 8.32) were associated with higher odds of anaemia among pregnant women.ConclusionsDuring pregnancy, intake of a low diversified diet, reduced food intake and low educational status were associated with higher odds of anaemia. Dietary counselling should be emphasised and strengthened in the existing prenatal health service program, with women strongly encouraged to increase their diversified food intake instead of reducing it during pregnancy.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"121-131"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9113016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The metabolic hypothesis for restrictive eating behaviors: A computational and evolutionary approach. 限制性饮食行为的代谢假说:计算和进化方法。
IF 1.9
Nutrition and health Pub Date : 2025-03-01 Epub Date: 2024-12-18 DOI: 10.1177/02601060241307104
Livio Tarchi, Giuseppe Pierpaolo Merola, Gaia Maiolini, Eleonora D'Areglia, Valdo Ricca, Giovanni Castellini
{"title":"The metabolic hypothesis for restrictive eating behaviors: A computational and evolutionary approach.","authors":"Livio Tarchi, Giuseppe Pierpaolo Merola, Gaia Maiolini, Eleonora D'Areglia, Valdo Ricca, Giovanni Castellini","doi":"10.1177/02601060241307104","DOIUrl":"10.1177/02601060241307104","url":null,"abstract":"<p><p>BackgroundRestrictive eating behaviors, widespread in humans and animals, are often conceptualized as maladaptive, but may serve adaptive purposes under specific circumstances.AimTo investigate the adaptive potential of restrictive eating behaviors.MethodsComputational models explored the relationship between food availability, basal metabolic rate, and restrictive eating behaviors. The evolutionary conservation of genes associated with both basal metabolic rate and restrictive eating behaviors was evaluated.ResultsThe propensity to engage in restrictive eating behaviors protected against negative energy balances at times of food volatility, implying ecological fitness potential. A high degree of conservation across species was observed in retrieved genes, implying selective evolutionary constraints.ConclusionRestrictive eating behaviors may represent a maladaptive outcome of evolutionary constraints on protective metabolic mechanisms. The higher prevalence of restrictive eating in women could stem from a greater reliance on protective strategies, highlighting the need for further exploration of sex-specific genetic and environmental interactions.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"9-14"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydrogen as an innovative nootropic in health and disease. 氢在健康和疾病中作为一种创新的营养素。
IF 1.9
Nutrition and health Pub Date : 2025-03-01 Epub Date: 2024-07-23 DOI: 10.1177/02601060241266389
Nikola Todorović, Sergej M Ostojic
{"title":"Hydrogen as an innovative nootropic in health and disease.","authors":"Nikola Todorović, Sergej M Ostojic","doi":"10.1177/02601060241266389","DOIUrl":"10.1177/02601060241266389","url":null,"abstract":"<p><p>Molecular hydrogen (H<sub>2</sub>, dihydrogen) is an antioxidant and signaling molecule with potent antioxidative, antiapoptotic, and anti-inflammatory properties. Despite the growing interest in H2 as a potential therapeutic agent, the evidence regarding its potential as a nootropic remains limited. Only a handful of studies on the human population have evaluated its effects, although there are suggestive indications of its efficacy. The present paper overviews H<sub>2</sub>'s potential as a novel agent for improving cognitive functions in health and disease contexts, highlighting its mechanisms of action and areas for further investigation. Current evidence suggests that H<sub>2</sub> improves executive function, alertness and memory in several clinical trials, from healthy young and elderly individuals to individuals with altered circadian rhythms, neurodegenerative disorders, and cancer. Further investigations are needed to confirm the potential positive effects of dihydrogen as a nootropic agent in both health and disease.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"59-64"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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