Nutrition and health最新文献

{"title":"<i>Lactococcus cremoris</i> YRC3780 improves subjective sleep quality in adults with sleep dissatisfaction: A randomized double-blind placebo-controlled study.","authors":"Ikumi Fujioka, Kenji Uchida","doi":"10.1177/02601060261476102","DOIUrl":"10.1177/02601060261476102","url":null,"abstract":"<p><p>Background<i>Lactococcus cremoris</i> YRC3780 (previously <i>Lactococcus lactis</i> subsp. <i>cremoris</i> YRC3780), isolated from kefir, has been suggested to improve sleep quality by acting on intestinal immune cells and promoting cytokine production and has been shown to improve subjective sleep quality in healthy young men without sleep problems.AimWe examined the effects of YRC3780 in subjects dissatisfied with their sleep.MethodsWe investigated the effects of daily YRC3780 intake for 8 weeks on sleep in a randomized, placebo-controlled, double-blind, parallel-group study involving 105 healthy Japanese adults with baseline Athens Insomnia Scale (AIS) scores of ≥6.SummaryAfter 8 weeks, the AIS score and the change from baseline score were significantly better in the YRC3780 group than in the placebo group. The YRC3780 group showed significant improvements compared with the placebo group in the scores for the individual AIS items related to \"sleep induction\" at 4 weeks and in those for \"functioning capacity during the day\" at 8 weeks. The percentage changes from baseline at 4 weeks for the Oguri-Shirakawa-Azumi Sleep Inventory Middle-aged and Aged version question \"fell asleep quickly\" and for the Japanese version of the Epworth Sleepiness Scale question about sleepiness while watching TV were significantly better in the YRC3780 group than in the placebo group. In conclusion, daily YRC3780 intake significantly improved sleep quality and alleviated daytime sleepiness and difficulty falling asleep in healthy Japanese adults with sleep complaints (UMIN-CTR, https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno = R000060004, UMIN000052586).</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261476102"},"PeriodicalIF":1.4,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148722157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are dietary plant cell wall polysaccharides key components to prevent/avert breast cancer?","authors":"María E Vago, Helena A Sterle, Marina Ciancia, Graciela A Cremaschi","doi":"10.1177/02601060261478370","DOIUrl":"10.1177/02601060261478370","url":null,"abstract":"<p><p>BackgroundPlant cell wall's polysaccharides constitute a fundamental source of energy, influencing voluntary intake and digestibility of food, and also affecting peristalsis and health of the digestive tract in animals and people. Because herbivores are less prone to cancer than meat eaters, over the last decades, different teams have investigated the role of plant polysaccharides in immune system activation.AimIn this work, we examine this research seeking to understand if dietary carbohydrates from plant cell walls can be justifiably considered effective components for preventing breast cancer, specifically as it's the most common type of cancer for women.MethodsWe evaluate results from <i>in vitro</i> and <i>in vivo</i> experiments, observational studies (prospective cohort studies) conducted on people (nonvegetarian and vegetarian), and research studies on animals (monogastric herbivores and ruminants).SummarySpecific studies evaluating fiber intake and quality over long periods are scarce, inconclusive, or show mixed results regarding the plant cell polysaccharides present in the diet (structural and storage polysaccharides). We conclude that at the moment, there is not enough causal evidence to justify a recommendation that plant cell walls can be justifiably considered effective components for preventing breast cancer. Proposed steps to follow: a people prospective cohort study with special emphasis on retrieving information about fiber intake and composition of the ingested fiber to better elucidate a causal link in the prevention of breast cancer. Furthermore, a long-life, systematic study on mammalian herbivorous animals for addressing the link specifically between plant cell wall polysaccharides and breast cancer incidence.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261478370"},"PeriodicalIF":1.4,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148724280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are sustainable plant-based diets suitable for all? A nutrigenetic perspective.","authors":"Eren Terzioğlu, Indrani Kalkan","doi":"10.1177/02601060261478364","DOIUrl":"10.1177/02601060261478364","url":null,"abstract":"<p><p>BackgroundWhile global nutrition policies increasingly promote plant-based diets for environmental sustainability, this approach may implicitly assume biological homogeneity and overlook interindividual genetic variability in nutrient metabolism.AimThis review evaluates potential molecular bottlenecks and genetic variations that may influence individual adaptation to plant-based dietary patterns, based on recent literature in nutrigenetics and micronutrient metabolism.MethodsPeer-reviewed literature published primarily between 2015 and 2025 was searched across PubMed, Web of Science, and Scopus using nutrigenetics- and plant-based nutrition-related terms; Google Scholar was additionally consulted for supplementary citation tracking. Foundational studies were included where mechanistically relevant. Studies lacking genotypic data, in vitro models without clinical relevance, and non-English publications were excluded.SummaryCurrent evidence suggests that the conversion efficiency of plant-derived precursors into biologically active forms differs according to polymorphisms in genes including fatty acid desaturases (<i>FADS1/FADS2</i>), beta-carotene oxygenase-1 (<i>BCO1</i>), and phosphatidylethanolamine N-methyltransferase (<i>PEMT</i>). Moreover, phytate-mediated constraints and variations affecting mineral absorption-transmembrane serine protease 6 (<i>TMPRSS6</i>) and solute carrier family 39 member 4 (<i>SLC39A4</i>)-and vitamin B12 transport-fucosyltransferase-2 (<i>FUT2</i>) and transcobalamin-2 (<i>TCN2</i>)-may increase susceptibility to subclinical micronutrient insufficiencies in genetically predisposed individuals. Although many associations reach statistical significance, their clinical impact varies across populations and depends on the overall dietary context. These genetic influences are not deterministic and may potentially be mitigated through targeted dietary planning and personalized supplementation. Precision nutrition frameworks incorporating genetic variability may improve dietary personalization; however, future large-scale longitudinal trials are required before these findings can address consensus clinical guidelines.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261478364"},"PeriodicalIF":1.4,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148723404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrition transition and hypertension in Latin America and the Caribbean: A systematic review.","authors":"Danladi C Husaini, Marianny Guerra, Griselda Cruz, Tomasa Vasquez, Garba M Sani","doi":"10.1177/02601060261477993","DOIUrl":"https://doi.org/10.1177/02601060261477993","url":null,"abstract":"<p><p>BackgroundThe nutrition transition in Latin America and the Caribbean (LAC) is shifting from traditional diets to Westernized patterns high in ultra-processed foods, coinciding with a growing hypertension epidemic. A synthesis of region-specific evidence is needed to inform culturally appropriate public health strategies.AimThis systematic review evaluates evidence from 2017 to 2025 on the association between dietary patterns and hypertension in LAC adults, analyzing socioecological determinants within the nutrition transition framework.MethodsFollowing Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we searched PubMed, Scopus, LILACS, and other databases for observational and intervention studies in LAC. Two reviewers independently performed screening, data extraction, and quality assessment using NIH and Cochrane tools. A narrative synthesis was conducted due to heterogeneity.SummaryTwelve studies were included. Traditional diets were associated with lower blood pressure (beta: -1.85 mmHg) and reduced hypertension prevalence (prevalence ratio (PR): 0.57), while Westernized diets and ultra-processed foods increased risk (beta: +2.09 mmHg; risk ratio: 1.35). Food insecurity was linked to 39% higher uncontrolled hypertension prevalence (PR: 1.39), while higher education was protective (odds ratio: 0.66). One randomized controlled trial showed a culturally tailored nutrition intervention improved dietary quality. The nutrition transition drives hypertension in LAC. Effective mitigation requires dual strategies: structural policies regulating ultra-processed foods and promoting healthy food environments, alongside culturally adapted interventions addressing socioecological barriers.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261477993"},"PeriodicalIF":1.4,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148707416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of diet quality and supplement use on fatigue, sleep, and quality of life in adults: A cross-sectional study.","authors":"Nour Batarseh, Anfal Al-Dalaeen, Fuad A Abdulla, Nadine N Abdelhadi","doi":"10.1177/02601060261477833","DOIUrl":"https://doi.org/10.1177/02601060261477833","url":null,"abstract":"<p><p>BackgroundPoor diet quality and fatigue adversely affect daily functioning and quality of life.AimThe present study explored associations between dietary patterns, sleep quality, and fatigue, with a focus on potential associations with supplement use.MethodsA cross-sectional study recruited 400 adults (276 females). Data were collected via a face-to-face survey using validated Arabic questionnaires.Summary35.5% of participants were aged 18-24 years, and the overall mean BMI was 25.9 ± 4.54 kg/m². The average daily energy intake was 2057.5±563.9 kcal. Mean Food Group Diversity Score (FGDS) and Global Dietary Recommendations (GDR) scores were 3.25 ± 2.60 and 9.86 ± 2.25, respectively. Only 22.5% of participants reported taking vitamins and minerals. Supplement users had higher mean GDR scores than non-users (10.53 ± 2.38 vs. 9.66 ± 2.17). Overall, 40.9% of participants reported fairly good subjective sleep quality. Females reported a higher fatigue score than males (26.29 ± 19.17 vs. 16.96 ± 20.10, <i>P</i>< 0.001). FGDS was negatively associated with fatigue (β = -0.121, <i>P</i> = 0.028) among participants and positively associated with sleep quality score (β = 0.200, <i>P</i> = 0.009) among males. Also, GRD was positively and significantly associated with quality of life (β = 0.092, <i>P</i> = 0.031). Finally, poor sleep quality and fatigue were significant predictors of lower quality of life (β= -0.267, <i>P</i>< 0.001 vs. β = -0.427, <i>P</i>< 0.001). In conclusion, poor sleep quality and fatigue are highly prevalent among Jordanian adults, particularly women. Higher diet quality was associated with better sleep quality and quality of life, highlighting the potential role of dietary patterns as a modifiable lifestyle factor.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261477833"},"PeriodicalIF":1.4,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148707457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy drink consumption among undergraduate students: Prevalence, regional variations, associated factors, and adverse effects - A systematic review and meta-analysis.","authors":"Zoriah Aziz, Sehrish Khalid, Muhammad Danish Badrul Hisham","doi":"10.1177/02601060261473065","DOIUrl":"https://doi.org/10.1177/02601060261473065","url":null,"abstract":"<p><p>BackgroundEnergy drink (ED) consumption is common among undergraduate students and has been linked with adverse health outcomes, including sleep disturbances, cardiovascular effects, and risk-related behaviours.AimThis study aimed to estimate the prevalence of ED consumption among undergraduate students and examine regional variations, associated factors, and reported adverse effects.MethodsA systematic review and meta-analysis were conducted in accordance with PRISMA guidelines. PubMed, Scopus, CINAHL, and Web of Science were searched from database inception to August 2025, with additional screening of Google Scholar and grey literature. Cross-sectional studies reporting ED consumption among undergraduate students were included. Three reviewers independently screened studies, extracted data, and assessed risk of bias using the Joanna Briggs Institute checklist. A random-effects meta-analysis was used to estimate the pooled prevalence.SummaryFifty-eight studies were included. The pooled prevalence of ED consumption among undergraduate students was 49.6% (95% CI: 39.8%-59.5%), although substantial heterogeneity was observed (<i>I</i>² = 99.6%). Subgroup analyses showed the highest prevalence in Africa (61%), followed by Asia (50%), North America (47%), and Europe (37%). Common motivations for consumption included staying awake, enhancing academic performance, and improving energy levels, while peer influence, marketing, affordability, and availability were identified as important contributing factors. Reported adverse effects primarily involved cardiovascular, neurological, and psychological symptoms. Overall, ED consumption appears to be common among undergraduate students and is associated with behavioural and environmental factors and a range of self-reported adverse effects. As the evidence is derived from cross-sectional studies, causal inferences cannot be made, highlighting the need for longitudinal research to better understand long-term health outcomes and inform targeted interventions.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261473065"},"PeriodicalIF":1.4,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148685290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal and newborn health in vegan and omnivore pregnancies: A prospective pilot study (PREGGIE).","authors":"Christian Koeder, Katharina Feuerlein, Virginie Stanislas, Tim Zerback, Stine Weder, Alfred Längler, Ute Alexy, Markus Keller","doi":"10.1177/02601060261474598","DOIUrl":"https://doi.org/10.1177/02601060261474598","url":null,"abstract":"<p><p>BackgroundFew studies have assessed health outcomes in pregnant vegans and their newborns.AimThis study aimed to examine this evidence gap.MethodsThis pilot study compared health parameters of pregnant vegans (<i>n = </i>32) and omnivores (<i>n = </i>13), as well as their newborns, in Germany (2019-2022). Maternal body mass index, weight and blood pressure were measured at gestational weeks 9-16 (t1) and 35-38 (t2). Additional assessments included maternal weight gain and excessive weight gain (from the beginning of pregnancy to t2), delivery method, gestational age, preterm birth, sex ratio, birth weight and length, small/large for gestational age, low birth weight, macrosomia, head circumference, and Apgar scores.SummaryNo significant differences were observed between the vegan and omnivore groups for any newborn outcomes, birth characteristics, or maternal health parameters. No preterm births occurred. Small for gestational age was observed in 2 vegan (6%) and 3 omnivore newborns (23%). Low birth weight (<2500 g) occurred in 1 vegan newborn (3%) and in no omnivore newborns. An Apgar score <10 at 10 min was recorded in 1 vegan (3%) and 1 (8%) omnivore newborn (both scoring 8).This study detected no clear adverse effects of a supplemented vegan diet (vitamin B12, iodine, vitamin D, omega-3 fatty acids) during pregnancy. Differences between vegans and omnivores cannot be excluded. The study was underpowered and baseline differences limit group comparability, validity, and generalizability. The study highlights key parameters and underscores the need to maximize group comparability in future research.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261474598"},"PeriodicalIF":1.4,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148664277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential effects of cayenne pepper in modulating cardiovascular risk markers in rats fed an atherogenic diet and exposed to inflammation.","authors":"Rachel S Goldberg, Deva S Plumlee, Kyrie Bloem, Nicole Hite, Mee Young Hong","doi":"10.1177/02601060261471743","DOIUrl":"https://doi.org/10.1177/02601060261471743","url":null,"abstract":"<p><p>BackgroundObesity, oxidative stress, and inflammation are major contributors to cardiovascular disease (CVD), the leading global cause of death. Capsaicin, the active compound in chili peppers, including cayenne pepper, has shown anti-inflammatory effects and may help reduce CVD risk. However, research on cayenne pepper's specific impact on CVD-related biomarkers is limited.AimThis study aimed to evaluate the effects of cayenne pepper on lipid metabolism, inflammation, and antioxidant capacity in dextran sodium sulfate (DSS)-treated rats fed an atherogenic diet.MethodsForty male Sprague-Dawley rats (21 days old) were randomly assigned to four groups (<i>n</i> = 10/group) in a 2 × 2 factorial design: atherogenic diet ± cayenne pepper (2.9%) for 28 days, with or without 3% DSS (an inflammation-inducing agent) for 24 h.SummaryRats fed cayenne pepper-supplemented diet showed lower body weight gain (<i>P</i> = 0.022) and epididymal fat mass (<i>P</i> = 0.037), along with increased high-density lipoprotein cholesterol levels (<i>P</i> = 0.029) and decreased low-density lipoprotein cholesterol (<i>P</i> = 0.002) and triglyceride levels (<i>P</i> = 0.048). C-reactive protein levels showed a decreasing trend (<i>P</i> = 0.056), while antioxidant enzyme activities, including superoxide dismutase, glutathione S-transferase, and glutathione peroxidase, were significantly higher (<i>P</i> < 0.001) in cayenne pepper-fed rats. Hepatic gene expression of inflammation marker cyclooxygenase-2 (<i>P</i> = 0.026), as well as the lipogenic genes fatty acid synthase (<i>P</i> = 0.002) and sterol regulatory element-binding protein 1 (<i>P</i> = 0.003), were decreased with cayenne pepper. These results suggest that cayenne pepper may modulate CVD-related risk factors through anti-inflammatory, lipid-modulating, and antioxidant mechanisms.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261471743"},"PeriodicalIF":1.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between dietary diversity and caries in preschool-age children.","authors":"Akane Kojima, Yuri Akiyama, Kanae Wada, Yuka Tanaka, Suzuka Gokyu, Haruka Yoshino, Takamitsu Natori, Kuniyasu Kamiya, Masahiko Kato","doi":"10.1177/02601060261471998","DOIUrl":"https://doi.org/10.1177/02601060261471998","url":null,"abstract":"<p><p>BackgroundFew studies have reported an association between dietary diversity and caries among preschool children.AimThis study aimed to clarify the association between dietary diversity and caries in preschoolers.MethodsThe data for this cross-sectional study were obtained by distributing questionnaires to the parents of preschool children (aged 3-6 years) in 2024, and 420 participants were analyzed. Children's dietary diversity was assessed using the dietary diversity score (DDS), which is the sum of the intake frequency of eight food groups (cereals, fish and shellfish, meat, eggs, soybeans and soy products, vegetables, fruits, and dairy products). Consumption of food at least once and less than once daily was scored as 1 and 0, respectively, for a maximum of 8 points. The DDS obtained was classified into three groups: low (0-2 points), moderate (3-5 points), and high (6-8 points). The presence or absence of caries was reported by the parents. Odds ratios and 95% confidence intervals were estimated using logistic regression analysis.SummaryCaries were present in 69 of the 420 children (16.4%). After adjustment for sex, age, frequency of consuming sweetened beverages, frequency of consuming sweets, sleep duration, and maternal education level, the odds ratios for the moderate- and high-DDS groups, compared with the low-DDS group, were 0.64 (95% confidence interval: 0.35-1.17) and 0.40 (95% confidence interval: 0.17-0.99), respectively. Dietary diversity was associated with caries independent of sex, age, frequency of sweetened beverages, frequency of sweets, sleep duration, and maternal education level among preschool children.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261471998"},"PeriodicalIF":1.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary intake and blood biomarker changes with a one-week pesco-vegetarian diet intervention supplemented with varying dose of ginger and curcumin: A single-blinded randomized clinical trial.","authors":"Kim Mossburg, Jerod Benjamin Matheny, Hisako Masuda","doi":"10.1177/02601060261468994","DOIUrl":"https://doi.org/10.1177/02601060261468994","url":null,"abstract":"<p><p>BackgroundThe pesco-vegetarian diet has been associated with favorable health outcomes. Ginger and curcumin are herbs with antioxidative properties and therapeutic effects.AimThe aim of this study was to conduct a preliminary investigation to study the health benefits of the short-term pesco-vegetarian diet intervention supplemented with ginger and curcumin.MethodsHealthy human volunteers were recruited to participate in a 1-week intervention with the pesco-vegetarian diet. Participants were divided into three subgroups to partake of 0, 1, or 2 doses of ginger and curcumin supplements (500 mg) per day. The adherence to the diet and its efficacy on changing macro- and micro-nutrient intake were investigated. Health benefits were assessed via blood analysis, diagnostic tests, and interviews.ResultsIntake of fiber increased while that of cholesterol was reduced in all three groups. Most notably, a significant decrease in blood high-density lipoprotein cholesterol (HDL-C) levels was observed in the 0 dose group but not in 1 or 2 dose groups. In addition, specific micro- and macro-nutrients whose levels were associated with changes in blood lipid levels, weight changes, and blood pressures were identified. For example, the level of omega-3 fatty acid intake was correlated to the reduction of blood low-density lipoprotein cholesterol and total cholesterol.ConclusionsUptake of herbal supplements in conjunction with the pesco-vegetarian diet appears to exert positive health impacts, such as lowering some blood lipid levels, even within a 1-week period. Additionally, our study suggests that ginger and curcumin supplements may have blunted the decrease in HDL-C levels associated with vegetarian diets.</p>","PeriodicalId":19352,"journal":{"name":"Nutrition and health","volume":" ","pages":"2601060261468994"},"PeriodicalIF":1.4,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}