NFS JournalPub Date : 2025-03-01Epub Date: 2025-01-31DOI: 10.1016/j.nfs.2025.100219
Jonas Pospiech, Johanita Kruger, Jan Frank
{"title":"Plant-based burger patties are a source of bioaccessible iron and zinc","authors":"Jonas Pospiech, Johanita Kruger, Jan Frank","doi":"10.1016/j.nfs.2025.100219","DOIUrl":"10.1016/j.nfs.2025.100219","url":null,"abstract":"<div><h3>Background</h3><div>The consumption of plant-based meat alternatives has increased substantially in recent years. However, due to the presence of absorption inhibitors, such as phytate, oxalate, and condensed tannins, the uptake of zinc and iron from plant foods may be low. We therefore quantified minerals (Fe, Zn), inhibitors (phytate, oxalate, condensed tannins), and enhancers (ascorbic acid, carotenoids) of mineral absorption in pea protein-, soy protein-, soy flour-, and sunflower protein-based burger patties and the resulting bioaccessibility of the contained iron and zinc conducting <em>in vitro</em> digestion experiments.</div></div><div><h3>Results</h3><div>The soy flour-based burger had nearly complete bioaccessibility for zinc (105 ± 6 %) and iron (101 ± 11 %), while the three other plant burgers had significantly lower bioaccessibilities (zinc, 9–12 %; iron, 43–57 %). The phytate but not the oxalate and condensed tannin contents of the patties were negatively correlated with the bioaccessibility of iron and zinc (<em>p</em> < 0.05).</div></div><div><h3>Conclusion</h3><div>Plant-based meat alternatives may be an important source of bioaccessible iron and zinc, if they contain low amounts of phytate, and may contribute to an adequate supply of these minerals.</div></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":"38 ","pages":"Article 100219"},"PeriodicalIF":4.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Changes in vitamin D2 content and physicochemical characteristics of food products enriched with UV-B irradiated oyster mushroom powder during cooking and storage","authors":"Chutikarn Kapcum , Nongnuch Sungayuth , Thitipak Theeratadsanakul , Wishita Sutthi , Kunchit Judprasong , Piyanut Sridonpai , Konpong Boonyingsathit , Rungtiwa Wongsagonsup","doi":"10.1016/j.nfs.2024.100203","DOIUrl":"10.1016/j.nfs.2024.100203","url":null,"abstract":"<div><div>UV-B irradiation has been shown to increase vitamin D<sub>2</sub> content in oyster mushrooms. This study investigated changes in vitamin D<sub>2</sub> content and the physicochemical properties of food products (i.e., alkaline noodles, Mantous, cookies, and extruded snacks) enriched with 10 % UV-B irradiated oyster mushroom powder during cooking and storage. After cooking, alkaline noodles and Mantous were stored at 4 °C for 8 days, while cookies and snacks were stored in an accelerated condition at 45 °C for 90 days. Vitamin D<sub>2</sub> content in alkaline noodles and Mantous remained unchanged after cooking, but declined in cookies and extruded snacks by 27 % and 55 %, respectively. During storage, vitamin D<sub>2</sub> content in Mantous and cookies did not change, but decreased in alkaline noodles and snacks by 19–38 % and 26–51 %, respectively. The total phenolic content and antioxidant activities of the food products generally increased after cooking, except for alkaline noodles, and generally decreased during storage, except for Mantous. The texture properties of all products also changed during storage, which could be related to moisture content within the products. This study illustrated that significant amounts of vitamin D<sub>2</sub> and phenolic compounds remained in the food products after cooking and storage, especially in Mantous and cookies, thereby promoting human health benefits.</div></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":"38 ","pages":"Article 100203"},"PeriodicalIF":4.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143172310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NFS JournalPub Date : 2025-03-01Epub Date: 2025-03-03DOI: 10.1016/j.nfs.2025.100221
Junhyo Cho , Eun-Ho Lee , Young-Je Cho , Yeonhwa Park
{"title":"Jatrorrhizine, an alkaloid isolated from Phellodendron amurense, reduces melanogenesis in mouse B16F10 melanoma cells","authors":"Junhyo Cho , Eun-Ho Lee , Young-Je Cho , Yeonhwa Park","doi":"10.1016/j.nfs.2025.100221","DOIUrl":"10.1016/j.nfs.2025.100221","url":null,"abstract":"<div><div>Jatrorrhizine isolated from <em>Phellodendron amurense</em> has been reported as one of the major phenolic alkaloid compounds. Previous studies indicated that jatrorrhizine has potential health benefits. In this study, we used jatrorrhizine isolated from <em>P. amurense</em> to determine its effects on melanogenesis using B16F10 mouse melanoma cells. Jatrorrhizine at 20–100 μM inhibited α-melanocyte-stimulating hormone-induced melanin biosynthesis without cytotoxicity. Treatment with jatrorrhizine inhibited melanocortin 1 receptor, increased transforming growth factor-β1, and inhibited microphthalmia transcription factor, tyrosinase-related protein-1, tyrosinase-related protein-2, tyrosinase expression, and tyrosinase activity compared to the α-MSH-treated control. In addition, treatment with jatrorrhizine inhibited <em>RAB27A</em> and <em>MYO5A</em>, which are key components of melanosome transport. The current results suggest that jatrorrhizine has the potential to be used in functional cosmetics and beauty foods to improve skin tone. Further <em>in vivo</em> studies using jatrorrhizine would be needed to support the current observations.</div></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":"38 ","pages":"Article 100221"},"PeriodicalIF":4.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143561885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NFS JournalPub Date : 2025-03-01Epub Date: 2025-01-23DOI: 10.1016/j.nfs.2025.100217
Ewa Korzeniewska , Ilona Gałązka-Czarnecka , Joanna Sekulska-Nalewajko , Jarosław Gocławski , Tomasz Dróźdż , Paweł Kiełbasa
{"title":"Assessment of changes in vitamin content and morphological characteristics in strawberries modified with a pulsed electric field using chromatography and optical coherence tomography","authors":"Ewa Korzeniewska , Ilona Gałązka-Czarnecka , Joanna Sekulska-Nalewajko , Jarosław Gocławski , Tomasz Dróźdż , Paweł Kiełbasa","doi":"10.1016/j.nfs.2025.100217","DOIUrl":"10.1016/j.nfs.2025.100217","url":null,"abstract":"<div><div>Vitamins B and C are crucial for maintaining human health, so it is important to develop effective methods to support their extraction from products of plant origin. The research conducted by the authors focused on modifying the content of these vitamins in dessert strawberries using a pulsed electric field (PEF) with an intensity of 1, 3 or 5 kV/cm. Experiments have shown that PEF treatment with an intensity of 1 kV/cm and 10 pulses for 10 s resulted in a significant improvement in vitamin content and extraction efficiency of vitamin C by 22 %, folic acid by 24 %, thiamine by more than 50 % and riboflavin by more than 60 %.</div><div>Optical coherence tomography imaging revealed texture changes in fruit pulp under the influence of PEF, related to the release of additional vitamins detected by chromatography methods.</div><div>Additionally, PEF treatment offers significant benefits in fruit processing, including improved dehydration characteristics, reduced time and energy required for freeze-drying, increased extraction efficiency, and potential improvements in bioactive compound content and antioxidant properties.</div><div>The research results may have practical applications in the analytical determination of vitamins C and B by improving the extraction efficiency. Moreover, the use of the PEF method can be important for producers of fruit products (including strawberries), as it enables them to improve the nutritional value of their products.</div></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":"38 ","pages":"Article 100217"},"PeriodicalIF":4.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143172498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of microencapsulation using β-cyclodextrin and β-glucan as coating agents on physicochemical properties and phytocannabinoids retention of cannabis flower oil extract","authors":"Worakrit Saiyasombat, Chanittha Yimpetch, Wimonphan Chathiran, Jaruwan Chimasangkanan, Warangkana Srichamnong","doi":"10.1016/j.nfs.2024.100209","DOIUrl":"10.1016/j.nfs.2024.100209","url":null,"abstract":"<div><div>Phytocannabinoids possess various biological activities; however, their limited aqueous solubility and poor stability present problems for effective utilization. Encapsulation is a highly effective method to improve the stability and solubility of cannabis extracts. The potential of β-glucan as a coating material for cannabis extract has not been extensively studied. This study aimed to investigate encapsulation of cannabis extracts by freeze-drying using β-glucan or β-cyclodextrin as coating agents. The extract was mixed with coating agent, with core-to-coating ratio of 1:1 and 1:2 (<em>w</em>/w). Tween 20 or 40 % ethanol were employed for preparing emulsion. Characterization was performed using contact angle, SEM, FT-IR, NMR and TGA. Phytocannabinoids and antioxidant properties were analyzed using LC-MS/MS and three antioxidant assays (DPPH, FRAP and ORAC). Results showed that different encapsulation conditions affect the phytocannabinoids contents and their morphology. The microencapsulation with Tween 20 at core-to-coating ratio of 1:1 can retain CBD and THC at 0.19 μg/g oil and 0.04–0.07 μg/g oil. SEM image showed granular structure in β-glucan encapsulated products. FT-IR, NMR and TGA confirmed microencapsulation formation. These microcapsules demonstrated high thermal stability with encapsulation efficiency ranging from 13.38 % to 64.80 %. All microcapsules exhibited various antioxidant activity. This study demonstrates the potential for developing water-soluble cannabinoids for food and pharmaceutical applications.</div></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":"38 ","pages":"Article 100209"},"PeriodicalIF":4.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143173324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NFS JournalPub Date : 2025-03-01Epub Date: 2024-12-16DOI: 10.1016/j.nfs.2024.100204
Mustapha Mbye , Abdelmoneim H. Ali , Afaf Kamal-Eldin , Fawzi Banat
{"title":"The impact of camel milk and its products on diabetes mellitus management: A review of bioactive components and therapeutic potential","authors":"Mustapha Mbye , Abdelmoneim H. Ali , Afaf Kamal-Eldin , Fawzi Banat","doi":"10.1016/j.nfs.2024.100204","DOIUrl":"10.1016/j.nfs.2024.100204","url":null,"abstract":"<div><div>Diabetes mellitus (DM) is a global health challenge with increasing prevalence. Camel milk (CM) and its derivatives have emerged as promising candidates for managing DM due to their unique composition and bioactive components, such as insulin-like proteins, lactoferrin, immunoglobulins, and oligosaccharides. These components exhibit hypoglycemic and anti-inflammatory properties, improving glycemic control, insulin sensitivity, and lipid profiles in individuals with DM. CM products, including fermented yogurt and powder formulations, have also shown beneficial effects on glucose metabolism and insulin regulation. The therapeutic effects of CM on DM are mediated through enhanced pancreatic β-cell function, modulation of insulin signaling pathways, and reduction of oxidative stress. Despite its potential, camel milk therapy in diabetes management faces several limitations. These include a lack of standardization in composition, limited clinical evidence, unclear mechanisms of action, and uncertainty regarding the optimal dose and duration of use. Comprehensive and robust clinical studies are essential to fully validate the therapeutic potential of camel milk and its derivatives. Previous reviews focus on using raw CM, with limited to no study on transformed camel milk products, such as fermented products, powder, and whey protein powders, which also possess anti-diabetic properties. This review discusses the effects of whole CM and its products, which form an effective, more practical, and easier to access than raw camel milk, and the mechanisms underlying the therapeutic potential of CM and its products in combating DM.</div></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":"38 ","pages":"Article 100204"},"PeriodicalIF":4.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143173323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NFS JournalPub Date : 2025-03-01Epub Date: 2024-12-16DOI: 10.1016/j.nfs.2024.100210
In Ho Cho , RanRan Cheng , Cheol Woon Jung , Tae Hyung Won , Daijie Wang , Hwan-Hee Jang , In Guk Hwang , Sung Won Kwon
{"title":"Effects of 1-Deoxynojirimycin on glycemic control: A systematic review and meta-analysis","authors":"In Ho Cho , RanRan Cheng , Cheol Woon Jung , Tae Hyung Won , Daijie Wang , Hwan-Hee Jang , In Guk Hwang , Sung Won Kwon","doi":"10.1016/j.nfs.2024.100210","DOIUrl":"10.1016/j.nfs.2024.100210","url":null,"abstract":"<div><div>This meta-analysis investigates the effects of 1-Deoxynojirimycin (DNJ), derived from mulberry leaves, on glycemic control in individuals with impaired glucose tolerance and type 2 diabetes. DNJ significantly reduced postprandial plasma glucose (PPG) at 30 min, postprandial plasma insulin (PPI) at 30 min, and both glucose and insulin incremental area under the curve (iAUC) at 120 min, with substantial heterogeneity across studies. These findings align with DNJ's role as an inhibitor of α-glucosidase and sucrase, delaying carbohydrate digestion and glucose absorption in the small intestine. However, the effects were short-lived, indicating DNJ's limited prolonged efficacy due to low bioavailability and rapid clearance. Future research is needed to further investigate its long-term effects and improve its therapeutic potential.</div></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":"38 ","pages":"Article 100210"},"PeriodicalIF":4.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143173326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NFS JournalPub Date : 2025-03-01Epub Date: 2025-01-16DOI: 10.1016/j.nfs.2025.100213
Nelly Fioroni , Maria Del Carmen Ponce de León Rodríguez , Nicolas Leconte , Claire Mouquet-Rivier , Caroline Guzman , Frédéric Boudard , Claudie Dhuique-Mayer , Myriam Collin , Anaïs Deglos , Emmanuelle Reboul , Ángela Bravo-Núñez , Caroline Laurent-Babot
{"title":"Development of an in vitro triculture model of intestine inflammation to assess the immunomodulatory properties of cassava and roselle, two African green leafy vegetables","authors":"Nelly Fioroni , Maria Del Carmen Ponce de León Rodríguez , Nicolas Leconte , Claire Mouquet-Rivier , Caroline Guzman , Frédéric Boudard , Claudie Dhuique-Mayer , Myriam Collin , Anaïs Deglos , Emmanuelle Reboul , Ángela Bravo-Núñez , Caroline Laurent-Babot","doi":"10.1016/j.nfs.2025.100213","DOIUrl":"10.1016/j.nfs.2025.100213","url":null,"abstract":"<div><div>The intestine integrity and function are crucial for nutrient absorption and to prevent the entry of harmful antigens. In sub-Saharan Africa, frequent infections and enteric dysfunction can cause intestinal inflammation that is associated with stunting. Therefore, to study the anti-inflammatory effects of cassava and roselle leaves, commonly consumed as sauces, we developed an <em>in vitro</em> triculture model of intestine inflammation using intestinal Caco-2 (colorectal adenocarcinoma) and HT29-MTX (goblet cell-like) together with the macrophage-like THP-1 cells. Stimulation of this model with lipopolysaccharide/interferon-γ resulted in mucus over-production, higher pro-inflammatory cytokine release and loss of intestinal barrier integrity due to increased permeability. Polar/non-polar extracts and digested sauces from cassava and roselle leaves reduced cytokine production in both intestinal and THP-1 cells to different extents and restored barrier integrity and permeability. The developed and validated triculture model of inflamed intestine thus demonstrated the anti-inflammatory properties of cassava and roselle leaves, despite moderate responses.</div></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":"38 ","pages":"Article 100213"},"PeriodicalIF":4.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143173329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NFS JournalPub Date : 2025-03-01Epub Date: 2025-03-04DOI: 10.1016/j.nfs.2025.100222
Masayuki Yamaga , Masakatsu Nohara , Akihisa Hata , Takashi Ito , Kayo Furumoto , Naomi Ohta , Jiro Miyamae , Hiroko Tani , Ayanori Yamaki , Noboru Fujitani
{"title":"Tissue distribution and accumulation of cinnamic acid derivatives from Brazilian green propolis in mice","authors":"Masayuki Yamaga , Masakatsu Nohara , Akihisa Hata , Takashi Ito , Kayo Furumoto , Naomi Ohta , Jiro Miyamae , Hiroko Tani , Ayanori Yamaki , Noboru Fujitani","doi":"10.1016/j.nfs.2025.100222","DOIUrl":"10.1016/j.nfs.2025.100222","url":null,"abstract":"<div><div>Cinnamic acid derivatives, particularly prenylated derivatives, are characteristic components of Brazilian green propolis (BGP) and have been attracting attention for their health benefits. However, few reports have investigated their tissue distribution. This study aimed to elucidate the tissue distribution of cinnamic acid derivatives and examine the effects of prenylation by administering BGP to mice. The distribution level of <em>p</em>-coumaric acid was higher in the kidneys than in the liver or intestine. Artepillin C was detected at higher levels in the liver and intestine than in the kidney, and was also distributed in the brain, muscle, spleen, pancreas, and adipose tissue. These results suggested that prenylation enhanced the tissue uptake of cinnamic acid derivatives, which may facilitate the understanding of their functional mechanisms and promote their use in pharmaceuticals and functional foods.</div></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":"38 ","pages":"Article 100222"},"PeriodicalIF":4.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143601374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NFS JournalPub Date : 2025-03-01Epub Date: 2025-03-07DOI: 10.1016/j.nfs.2025.100223
Patryk Adamski, Arkadiusz Zakrzewski, Patryk Wiśniewski, Wioleta Chajęcka-Wierzchowska, Anna Zadernowska
{"title":"High-pressure processing (HPP) alters tetracycline resistance in Listeria monocytogenes: A phenotypic and genotypic study","authors":"Patryk Adamski, Arkadiusz Zakrzewski, Patryk Wiśniewski, Wioleta Chajęcka-Wierzchowska, Anna Zadernowska","doi":"10.1016/j.nfs.2025.100223","DOIUrl":"10.1016/j.nfs.2025.100223","url":null,"abstract":"<div><div>This study insights into the effects of high-pressure processing (HPP) on the phenotypic resistance and expression of tetracycline resistance genes (<em>tetA</em>_1, <em>tetA</em>_2, <em>tetA</em>_3, <em>tetC</em>, <em>tetR</em>) in <em>Listeria monocytogenes</em> strains. A total of 29 strains were tested for minimum inhibitory concentration values (MIC) of tetracycline before and after HPP treatment (200 MPa/5 min). Results showed a significant increase in MIC values post-treatment, with 7 % of the strains exhibiting resistance. Gene expression analysis revealed overexpression of <em>tetA</em>_1 and <em>tetA</em>_2 genes, while <em>tetA</em>_3, <em>tetC</em>, and <em>tetR</em> showed varied responses, suggesting a strain specific expression pattern. These findings indicate that HPP induced stress may influence the development of antibiotic resistance in L. <em>monocytogenes</em>, highlighting the importance of monitoring resistance genes in food safety protocols.</div></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":"38 ","pages":"Article 100223"},"PeriodicalIF":4.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}