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Stability of ellagitannins in unclarified juices and purees of raspberry and blackberry fruit during one-year storage period 覆盆子和黑莓未澄清果汁和果泥中一年内鞣花丹宁的稳定性
NFS Journal Pub Date : 2023-11-01 DOI: 10.1016/j.nfs.2023.100155
Agnieszka Hejduk, Michał Sójka, Robert Klewicki
{"title":"Stability of ellagitannins in unclarified juices and purees of raspberry and blackberry fruit during one-year storage period","authors":"Agnieszka Hejduk,&nbsp;Michał Sójka,&nbsp;Robert Klewicki","doi":"10.1016/j.nfs.2023.100155","DOIUrl":"https://doi.org/10.1016/j.nfs.2023.100155","url":null,"abstract":"<div><p>The paper presents the stability of ellagitannins (ETs), ellagic acid and conjugates (EAC) in unclarified juices and purees obtained from raspberries and blackberries. The innovation was to compare 2 different products with a variable composition in quantity and quality ETs coming from two different fruits. The preserves were stored for 12 months at three temperatures: −20, 4 and 20 °C (±2 °C). Analysis was performed every 3 months, using HPLC-DAD and LC-MS. In the presented research the degree of degradation of the overall of ETs + EAC was determined and the transformation of individual ETs was described. The ratio of monomeric, dimeric, trimeric and tetrameric compounds with respect to the sum of ETs and EAC and changes in their concentration over time were also determined. Additionally, the influence of time and temperature on the stability of ETs + EAC of different molecular weights was investigated using the Spearman correlation. Moreover, the stability of the oligomers characteristic of raspberries and blackberries was determined.</p><p>Purees were characterized by 5–6 times higher content of ETs + EAC, however, these compounds were decreased much faster compared to juices. In purees, the decrease of individual high-molecular ETs was much faster than in juices and was dependent on temperature and storage time. A difference in the decrease rate of the oligomers lambertianin C (LC) and sanguiin H-6 (SH-6) was observed. The highest degree of decrease was recorded at the highest temperature; after a year, in blackberry puree, 36% of SH-6 and over 60% of LC were decrease, in raspberry puree - 29% SH-6 and 50% LC.</p></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2352364623000342/pdfft?md5=dd5e09e614fca0938128d081d67ab886&pid=1-s2.0-S2352364623000342-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92024590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of herbal teas in reducing the starch digestibility of cooked rice (Oryza sativa L.): An in vitro co-digestion study 凉茶在降低稻米淀粉消化率中的作用:体外共消化研究
NFS Journal Pub Date : 2023-10-14 DOI: 10.1016/j.nfs.2023.100154
Thiraphong Aumasa , Yukiharu Ogawa , Jaspreet Singh , Worawan Panpipat , Natthawuddhi Donlao
{"title":"The role of herbal teas in reducing the starch digestibility of cooked rice (Oryza sativa L.): An in vitro co-digestion study","authors":"Thiraphong Aumasa ,&nbsp;Yukiharu Ogawa ,&nbsp;Jaspreet Singh ,&nbsp;Worawan Panpipat ,&nbsp;Natthawuddhi Donlao","doi":"10.1016/j.nfs.2023.100154","DOIUrl":"https://doi.org/10.1016/j.nfs.2023.100154","url":null,"abstract":"<div><p>Herbal teas are well known for their antidiabetic effects due to the abundance of phenolic acids, flavonoids, and tannins. An <em>in vitro</em> co-digestion test was conducted to observe influence of herbal teas (HTs) <em>i.e.</em>, beal fruit (BA), mulberry leaf (MB), gymnema leaf (GM), and chrysanthemum flower (CS) on starch digestibility of cooked rice and to elucidate correlation analysis of phytochemicals and their antioxidant activities during <em>in vitro</em> starch hydrolysis (SH). HTs prepared from GM and MB showed highest reduction of SH, kinetic constant and estimated glycemic index (eGI) of cooked rice, followed by BA and CS. Besides, MB and GM teas decreased the eGI of cooked rice up to 15%, followed by BA and CS teas, respectively. Phytochemicals and their antioxidant activities were positively correlated to SH, with both parameters displaying a higher decrease in intestinal phase when compared to gastric phase during <em>in vitro</em> co-digestion. These results indicate a strong interaction among phytochemicals and α-amylase in influencing glycaemic parameters. Thus, HTs has the potential to provide functional health benefits in lowering postprandrial hyperglycemia.</p></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50176667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolation and identification of a bioactive compound from Japanese red pine (Pinus densiflora) tea and its antioxidative effects on vascular endothelial cells 赤松茶活性成分的分离鉴定及其对血管内皮细胞的抗氧化作用
NFS Journal Pub Date : 2023-10-10 DOI: 10.1016/j.nfs.2023.100153
WenQian Jiang , Yuka Hattori , WonJune Lee , YiQian Zhang , KaiNing Zhang , Shojiro Hishiyama , Tomoko Shimokawa , Hitoshi Miyazaki , Shigeki Yoshida
{"title":"Isolation and identification of a bioactive compound from Japanese red pine (Pinus densiflora) tea and its antioxidative effects on vascular endothelial cells","authors":"WenQian Jiang ,&nbsp;Yuka Hattori ,&nbsp;WonJune Lee ,&nbsp;YiQian Zhang ,&nbsp;KaiNing Zhang ,&nbsp;Shojiro Hishiyama ,&nbsp;Tomoko Shimokawa ,&nbsp;Hitoshi Miyazaki ,&nbsp;Shigeki Yoshida","doi":"10.1016/j.nfs.2023.100153","DOIUrl":"https://doi.org/10.1016/j.nfs.2023.100153","url":null,"abstract":"<div><p>The bioactive compound, which showed a potent nitric oxide production stimulation effect, was isolated from Japanese red pine tea and identified as (+)-catechin. Compared with (−)-epigallocatechin 3-<em>O</em>-gallate and (−)-catechin, (+)-catechin exhibited greater NO production promotion and protection from H<sub>2</sub>O<sub>2</sub>-induced oxidative stress in vascular endothelial cells. The (+)-catechin content of Japanese red pine tea was found to be higher than that of buckwheat or green tea, both of which are known to contain (+)-catechin. This study indicated that (+)-catechin could be used as a potential functional ingredient for endothelium function protection and provides a basis for the use of red pine tea in endothelium dysfunction prevention in the future.</p></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50176671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytochemical composition, anti-amylase and anti-acetylcholinesterase activities of leaf extracts and herbal tea of Dolichandrone serrulata (DC.) seem 细叶多力雄酮叶提取物和凉茶的植物化学成分、抗淀粉酶和抗乙酰胆碱酯酶活性
NFS Journal Pub Date : 2023-09-27 DOI: 10.1016/j.nfs.2023.100152
Sirikul Thummajitsakul , Kullanat Nattee , Pornapa Nathunli , Chompoonick Promprieng , Rujisaya Anekwasinchai , Kun Silprasit
{"title":"Phytochemical composition, anti-amylase and anti-acetylcholinesterase activities of leaf extracts and herbal tea of Dolichandrone serrulata (DC.) seem","authors":"Sirikul Thummajitsakul ,&nbsp;Kullanat Nattee ,&nbsp;Pornapa Nathunli ,&nbsp;Chompoonick Promprieng ,&nbsp;Rujisaya Anekwasinchai ,&nbsp;Kun Silprasit","doi":"10.1016/j.nfs.2023.100152","DOIUrl":"https://doi.org/10.1016/j.nfs.2023.100152","url":null,"abstract":"<div><p>The number of elderly population is continually growing in Thailand. Major health problems mostly occurred in the elder are non-communicable diseases namely Alzheimer's disease and type 2 diabetes mellitus. In current study, phytochemical composition, anti-amylase and anti-acetylcholinesterase activities of leaf extracts and herbal tea from <em>Dolichandrone serrulata</em> (DC.) Seem were determined. The result showed that extracts and herbal tea samples of <em>D. serrulata</em> leaves had effective in inhibition of amylase (an effective concentration at half maximum (EC<sub>50</sub>) = 1.21 to 23.80 mg/ml) and acetylcholinesterase activities (EC<sub>50</sub> = 2.63 to 49.55 mg/ml). The effect of infusion time on the inhibition of amylase indicated that the best infusion time for preparing herbal tea beverage was 3 min, while the inhibition of acetylcholinesterase was 5 min. The fourier transform infrared spectroscopy (FTIR) and gas chromatograph - mass spectrometer (GC–MS) data indicated the presence of phytochemicals in the extracts and herbal tea samples related to phenolic compounds and flavonoids. The principal component analysis (PCA) result from FTIR data could discriminate herbal tea samples from the ethanol and aqueous extracts better than the PCA biplot of anti-amylase activity and anti-acetylcholinesterase activity.</p></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50176668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Micronutrients and the evolution of the human brain 微量营养素与人类大脑的进化
NFS Journal Pub Date : 2023-09-22 DOI: 10.1016/j.nfs.2023.100150
Hans K. Biesalski
{"title":"Micronutrients and the evolution of the human brain","authors":"Hans K. Biesalski","doi":"10.1016/j.nfs.2023.100150","DOIUrl":"https://doi.org/10.1016/j.nfs.2023.100150","url":null,"abstract":"<div><p>Several theories describe the increasing enlargement of the human brain because of environmental changes or dietary alterations. The environmental changes led to a change in diet quality (micronutrient density) because of changes in food foraging, which ensured that a growing brain was adequately supplied with energy and essential micronutrients for growth. The hippocampus is a direct link between nutrition and the environment, which is necessary for adapting to a changing climate. The adaptation then improves foraging success and enables better food quality and thus favors the development of the hippocampus, which in turn influences the development of other brain regions.</p><p>The extraordinary ability of our ancestors for persistent running not only favored hunting but also had direct effects on hormones that support brain development. The connection between physical exercise, nutrition, and plasticity of the hippocampus and the resulting adaptation to changing environmental conditions is essential for triggering or stimulating brain development. As the <em>variability selection hypothesis</em> proposes, fluctuations in environmental conditions need a short adaptive answer, which may become genetically fixed and selected. The presented hypothesis allows a meaningful combination of the different theories of brain development (pulse climate, variability selection, amplifier lakes) and nutrition theories (aquatic, cooking, energy).</p><p>The assumption that the hippocampus, as a “central sensory organ”, detects new events and enables an adaptive response is not an isolated assumption for the hippocampus since other brain regions can also react similarly with synaptic plasticity. Through adult hippocampal neurogenesis (AHN), which is unique only in the hippocampus and synaptic plasticity, there is the possibility of detection and (neurological) storage of previously unknown events and linking them to other cortical areas, which may increase cortical volume.</p></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50176670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selected lactobacilli isolated from Thai foods for production of fermented dairy products with cholesterol lowering potential 从泰国食品中分离的乳酸杆菌用于生产具有降低胆固醇潜力的发酵乳制品
NFS Journal Pub Date : 2023-09-22 DOI: 10.1016/j.nfs.2023.100151
Pornchanok Paongphan , Srivikorn Ditudompo , Porntipha Vitheejongjaroen , Ulisa Pachekrepapol , Malai Taweechotipatr
{"title":"Selected lactobacilli isolated from Thai foods for production of fermented dairy products with cholesterol lowering potential","authors":"Pornchanok Paongphan ,&nbsp;Srivikorn Ditudompo ,&nbsp;Porntipha Vitheejongjaroen ,&nbsp;Ulisa Pachekrepapol ,&nbsp;Malai Taweechotipatr","doi":"10.1016/j.nfs.2023.100151","DOIUrl":"https://doi.org/10.1016/j.nfs.2023.100151","url":null,"abstract":"<div><p>One of the benefits of probiotics is reduction of cholesterol by bile salt hydrolase (BSH) enzyme. This study aims to investigate the BSH activity of probiotics derived from fermented foods and to investigate the potential use of selected isolates in fermented dairy products. In this study, 55 isolates of lactic acid bacteria (LAB) were evaluated for their potential BSH activity. Three isolates identified as <em>Lactiplantibacillus paraplantarum</em> MN, <em>Lactiplantibacillus plantarum</em> MN2 and <em>Lactobacillus gasseri</em> SM were selected for their strong BSH activity. All three strains exhibited resistance to pH 3.0 and 4.0 with the number of survival cells around 7.8 and 8.1 log CFU/ml, respectively. They also survived in bile concentration of 0.3% and 0.8% and possessed moderate hydrophobicity. The selected strains and the mixed of three strains at ratio 1:1:1 were used in the production of fermented milk products. All strains and the mixture of three could maintain BSH activity in fermented milk products and survived throughout the storage duration of 28 days. With the properties of good probiotics, these strains could be potentially used in functional dairy products with cholesterol reduction property.</p></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50176669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mung bean seed coat water extract restores insulin sensitivity via upregulation of antioxidant defense system and downregulation of inflammation in insulin-resistant HepG2 cells 绿豆种皮水提取物通过上调抗胰岛素HepG2细胞的抗氧化防御系统和下调炎症来恢复胰岛素敏感性
NFS Journal Pub Date : 2023-08-01 DOI: 10.1016/j.nfs.2023.100145
Vipawanee Pavasutti , Chomdao Sinthuvanich , Ngampuk Tayana , Sumet Kongkiatpaiboon , Sudathip Sae-tan
{"title":"Mung bean seed coat water extract restores insulin sensitivity via upregulation of antioxidant defense system and downregulation of inflammation in insulin-resistant HepG2 cells","authors":"Vipawanee Pavasutti ,&nbsp;Chomdao Sinthuvanich ,&nbsp;Ngampuk Tayana ,&nbsp;Sumet Kongkiatpaiboon ,&nbsp;Sudathip Sae-tan","doi":"10.1016/j.nfs.2023.100145","DOIUrl":"10.1016/j.nfs.2023.100145","url":null,"abstract":"<div><p>Insulin resistance is the main cause of type 2 diabetes. Mung bean possesses many health benefits mainly related to polyphenols, which is abundant in mung bean seed coat. Total phenolic content in mung bean seed coat water extract (MSWE) was 0.62 ± 0.00 mg gallic acid equivalents (GAE)/g extract with antioxidant activity (IC<sub>50</sub> = 0.16 ± 0.01 mg/mL). Vitexin and isovitexin were the major flavonoids in MSWE. MSWE increased cellular glucose uptake and reduced intracellular reactive oxygen species (ROS) in insulin-resistant HepG2 cells. MSWE upregulated IRS-1, FGFR1, PI3K, and AKT expression, while downregulated FOXO1, PEPCK, and GSK3. MSWE modulated the expression of antioxidant genes including NRF2, KEAP1, HO-1, and NQO1. MSWE also downregulated genes related to inflammation (IL-6, IL-1β, TNF-α, PTP<img>1B, and p53). In conclusion, MSWE restored insulin sensitivity possibly through the reduction of ROS-associated inflammation by regulating GSK3/NRF2/KEAP1, downregulating PTP-1B and p53, as well as upregulating IRS-1/FGFR1/PI3K/AKT in insulin-resistant HepG2 cells.</p></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43520150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Supplementation of drinkable yogurt (Laban) from Camel milk with fruit purees improves its quality and sensory properties 从骆驼奶中添加水果泥的可饮用酸奶(拉班)可以改善其质量和感官特性
NFS Journal Pub Date : 2023-08-01 DOI: 10.1016/j.nfs.2023.100143
Bhawna Sobti, Rayyan Mohamed Saeed Alhefeiti, Fatima Alsayedahmed Alahdali, Maitha Ali Mohammed Al Samri, Afaf Kamal-Eldin
{"title":"Supplementation of drinkable yogurt (Laban) from Camel milk with fruit purees improves its quality and sensory properties","authors":"Bhawna Sobti,&nbsp;Rayyan Mohamed Saeed Alhefeiti,&nbsp;Fatima Alsayedahmed Alahdali,&nbsp;Maitha Ali Mohammed Al Samri,&nbsp;Afaf Kamal-Eldin","doi":"10.1016/j.nfs.2023.100143","DOIUrl":"10.1016/j.nfs.2023.100143","url":null,"abstract":"<div><h3>Background</h3><p>Camel milk (CM) and its fermentation products have acclaimed nutritional and health benefits, although they are often associated with low marketability because of a unique flavor, which is unpleasant to certain consumers. Incorporating fruit purees is an attractive method of adding a pleasant taste and masking the undesirable flavor in such dairy products.</p></div><div><h3>Methods</h3><p>We investigated the effects of supplementing plain fermented CM laban with pectin (0.2%) and a fruit puree (apricot, blueberry, mango, peach, pineapple, or strawberry) of varying concentrations (0%, 5%, 15%, and 25%) on the products' physicochemical, rheological, antioxidant, and sensory properties. The labans were analyzed for dry matter content, color (L*, a*, b*), pH, titratable acidity, and rheology. Total phenolic content and antioxidant property were determined using Folin–Ciocalteu and ABTS methods and sensory profile was studied using quantitative descriptive analysis.</p></div><div><h3>Results and discussion</h3><p>The labans fortified with 15% and 25% purees had higher dry matter content than the control samples. Addition of fruit purees darkened the color of the laban samples and lowered the L* value but did not affect their titratable acidity, except for the apricot puree. Labans containing blueberry, pineapple, and strawberry purees had higher whey-off than those containing peach, apricot, mango, or the control samples. The storage and loss moduli, and viscosity values of laban samples supplemented with peach or pineapple puree (at 15% and 25%, and at 25%, respectively) were increased compared to the other samples. The power law model sufficiently explained the flow of all labans, indicating a shear-thinning behavior. The addition of purees increased the total phenolic content and antioxidant activities of all labans, while peach puree in particular, improved the sensory quality of the CM laban, owing to its high fiber and protein content and low total soluble solids.</p></div><div><h3>Conclusion</h3><p>A 25% peach puree significantly improved all sensory properties of CM labans.</p></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44442355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Compositional analysis of phytochemicals and polysaccharides from Senegalese plant ingredients: Adansonia digitata (baobab), Moringa oleifera (moringa) and Hibsicus sabdariffa (hibiscus) 塞内加尔产猴面包树(猴面包树)、辣木(辣木)和木槿(芙蓉)中植物化学成分和多糖的组成分析
NFS Journal Pub Date : 2023-08-01 DOI: 10.1016/j.nfs.2023.100144
Hawi Debelo , Chelsey Fiecke , Anton Terekhov , Bradley Reuhs , Bruce Hamaker , Mario G. Ferruzzi
{"title":"Compositional analysis of phytochemicals and polysaccharides from Senegalese plant ingredients: Adansonia digitata (baobab), Moringa oleifera (moringa) and Hibsicus sabdariffa (hibiscus)","authors":"Hawi Debelo ,&nbsp;Chelsey Fiecke ,&nbsp;Anton Terekhov ,&nbsp;Bradley Reuhs ,&nbsp;Bruce Hamaker ,&nbsp;Mario G. Ferruzzi","doi":"10.1016/j.nfs.2023.100144","DOIUrl":"10.1016/j.nfs.2023.100144","url":null,"abstract":"<div><p>Certain indigenous African plant materials, including <em>Adansonia digitata</em> (baobab), <em>Moringa oleifera</em> (moringa), and <em>Hibiscus sabdariffa</em> (hibiscus) could be leveraged in food-to-food fortification strategies due to their high content of nutrients, dietary fiber, and phenolic compounds. However, more studies are needed to understand the nutritional composition of commercially available food ingredients. The objective of this study was to examine the phytochemical and polysaccharide compositions of commercially available baobab, moringa, and hibiscus ingredients from Senegal. Characterization of carotenoids, tocopherols, phenolic compounds, monosaccharide composition, and glycosyl linkage was carried out. We observed that moringa contained the greatest content of carotenoids and tocopherols. Moringa also contained significant amounts of the flavonols quercetin 3-<em>O</em>-glucoside and quercetin 3-<em>O</em>-rutinoside, while baobab had greater concentrations of flavan-3-ols. Substantial content of anthocyanins was observed for hibiscus, but not moringa or baobab. The predominant monosaccharide in baobab was xylose, while hibiscus was a combination of xylose, galactose, and glucose. The primary monosaccharides in moringa were galactose and glucose. Based on our glycosyl linkage analysis, (1 → 2)- and (1 → 2,4)-linked rhamnose were attributed to rhamnogalacturonan-I, while (1 → 4)-linked glucose and (Terminal →)-linked xylose were attributed to xyloglucans. The phytochemical and polysaccharide characterization of baobab, moringa, and hibiscus suggested that delivery of micronutrients, such as iron and carotenoids, could be impacted when applied as functional food ingredients.</p></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44813467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aronia juice improves working memory and suppresses δ-secretase activity in 5XFAD mice 野荆芥汁改善5XFAD小鼠的工作记忆并抑制δ-分泌酶活性
NFS Journal Pub Date : 2023-08-01 DOI: 10.1016/j.nfs.2023.100146
Takuya Yamane , Momoko Imai , Satoshi Handa , Hideo Ihara , Tatsuji Sakamoto , Tetsuo Ishida , Takenori Nakagaki , Susumu Uchiyama
{"title":"Aronia juice improves working memory and suppresses δ-secretase activity in 5XFAD mice","authors":"Takuya Yamane ,&nbsp;Momoko Imai ,&nbsp;Satoshi Handa ,&nbsp;Hideo Ihara ,&nbsp;Tatsuji Sakamoto ,&nbsp;Tetsuo Ishida ,&nbsp;Takenori Nakagaki ,&nbsp;Susumu Uchiyama","doi":"10.1016/j.nfs.2023.100146","DOIUrl":"10.1016/j.nfs.2023.100146","url":null,"abstract":"<div><p>Asparagine endopeptidase (AEP) cleaves amyloid precursor protein to facilitate amyloid β (Aβ) production in the brain. Aronia berry (<em>Aronia melanocarpa</em>) has various beneficial effects on health through inhibition of enzymes such as dipeptidyl peptidase IV. In this study, to examine neuroprotective effects of aronia juice (AJ), AJ was given to male 5XFAD Alzheimer's disease model mice via drinking bottles over a period from 2 weeks to 12 weeks of age. AJ intake improved the performance of Y-maze test in 5XFAD mice, and suppressed the δ-secretase activity in the mouse brains. AJ intake reduced significantly Aβ deposition in the brain. AJ reduced δ-secretase activity in human neuroblastoma SH-SY5Y cells. Out of five fractions (F1–F5) obtained from AJ, only F5 reduced δ-secretase activity in SH-SY5Y cells in a dose-dependent manner. LC-MS/MS analysis suggested that F5 contains three quercetin glycosides. AJ has neuroprotective function through inhibition of δ-secretase activity of AEP.</p></div>","PeriodicalId":19294,"journal":{"name":"NFS Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47680280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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