Neurosciences最新文献_第9页

Vagus nerve stimulation in medically refractory epilepsy: Adverse effects and clinical correlates. 迷走神经刺激治疗药物难治性癫痫：不良反应和临床相关性。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-01-01 DOI: 10.17712/nsj.2024.1.20230006

Khaled A Alshehri, Shaima H Abuhulayqah, Mohammed A Asiry, Suad A Alyamani

{"title":"Vagus nerve stimulation in medically refractory epilepsy: Adverse effects and clinical correlates.","authors":"Khaled A Alshehri, Shaima H Abuhulayqah, Mohammed A Asiry, Suad A Alyamani","doi":"10.17712/nsj.2024.1.20230006","DOIUrl":"10.17712/nsj.2024.1.20230006","url":null,"abstract":"Objectives: To assess the frequency of adverse effects among pediatric and adult patients and the clinical variables associated with a higher probability of developing side effects.Methods: This retrospective study enrolled pediatric and adult patients who underwent Vagus nerve stimulation (VNS) implantation at our institution and had documented follow-up during clinic visits for at least 6 months after implantation. Data collected included demographic information, epilepsy diagnosis, and device data.Results: A total of 43 patients with drug-resistant epilepsy who received a VNS device at our institution were enrolled. The median follow-up period was 12 months. Fourteen patients (32.55%) reported no side effects from VNS therapy. Side effects ranged from mild to severe, with significant side effects observed in 8 patients. Data on therapy efficacy were collected, and 10 patients (23.26%) reported no change in seizure frequency following device implantation.Conclusion: This study demonstrates that VNS is an important adjunct treatment option for epilepsy patients. Dysphagia and dyspnea can be significant adverse effects leading to treatment discontinuation, aspiration pneumonia, intensive care unit (ICU) admission, and prolonged hospital stay. These effects are more frequent in patients with symptomatic generalized epilepsy, global developmental delay at baseline, previous ICU admissions, abnormal brain magnetic resonance imaging findings, and seizures with multiple semiologies.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 1","pages":"10-17"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139403756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on: A relapse of Guillain-Barre syndrome caused by SARS-CoV-2 is not uncommon. 评论由 SARS-CoV-2 引起的格林-巴利综合征复发并不少见。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-01-01 DOI: 10.17712/nsj.2024.1.20230104

Sounira Mehri, Josef Finsterer, Vladimir S Jankovic

引用次数: 0

Comment on: Hydrodiscectomy is not indicated in patients with chronic radicular pain as long as all differentials have been ruled out. 评论：只要排除了所有鉴别因素，慢性根性疼痛患者就不适合进行水动力切除术。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-01-01 DOI: 10.17712/nsj.2024.1.20230101

Josef Finsterer, Mohamed A Elkhalifa

引用次数: 0

Do allergic conditions increase the risk of developing Long-COVID after SARS-CoV-2 infection? 过敏性疾病是否会增加感染 SARS-CoV-2 后患 Long-COVID 的风险？

IF 0.9 4区医学

Neurosciences Pub Date : 2024-01-01

引用次数: 0

HbA1c and risk factors' prevalence in patients with stroke: a retrospective study in a tertiary care hospital in Saudi Arabia. 中风患者的 HbA1c 和风险因素流行率：沙特阿拉伯一家三级医院的回顾性研究。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-01-01 DOI: 10.17712/nsj.2024.1.20230037

Faisal K Alfakeeh, Yazeed M Alghamdi, Bassam F Alharbi, Abdulaziz M Alotaibi, Khalid A Alsaleh, Abdullah M Alshubaili, Ryan H Mcrabi, Farhan K Alenazi, Awad Almuklass

{"title":"HbA1c and risk factors' prevalence in patients with stroke: a retrospective study in a tertiary care hospital in Saudi Arabia.","authors":"Faisal K Alfakeeh, Yazeed M Alghamdi, Bassam F Alharbi, Abdulaziz M Alotaibi, Khalid A Alsaleh, Abdullah M Alshubaili, Ryan H Mcrabi, Farhan K Alenazi, Awad Almuklass","doi":"10.17712/nsj.2024.1.20230037","DOIUrl":"10.17712/nsj.2024.1.20230037","url":null,"abstract":"Objectives: To determine the relationship between hemoglobin A1c (HbA1c) and different types of stroke, and how different comorbidities and risk factors are related to the occurrence of stroke in a Saudi Arabian tertiary care hospital.Methods: This retrospective study was conducted at King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia. The study included patients who experienced either hemorrhagic stroke (HS), ischemic stroke (IS), or transient ischemic attack (TIA) between 2015 and 2020.Results: In total, 976 patients were included, of whom 670 were males (68.6%). The incidence of HS was significantly higher in males compared to females (14.2% vs. 6.9%), whereas the incidence of IS was higher in females (76.8% vs. 74.6%) (p=0.001). Ischemic stroke was significantly higher in the 65 years or older age group, whereas HS was comparatively higher among those aged <65 years. The means HbA1c levels in all three types of stroke were abnormally high. However, HbA1c levels were significantly higher in IS than in the other 2 stroke types (p=0.017). The HbA1c levels showed statistically significant differences between the different types of stroke, where the estimated marginal means were higher in patients with IS with a small effect size. Heart disease was also more prevalent in the IS group. Stroke-related mortality was reported in 16 patients and was significantly higher in the IS group than in the HS group.Conclusion: The HbA1c levels were elevated in all types of stroke, significantly in IS. Controlling patients' HbA1c and other modifiable risk factors could significantly reduce the risk of stroke.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 1","pages":"18-24"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139403752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pioglitazone and barriers to effective post-stroke comorbidity management in stroke survivors with diabetes. 吡格列酮与中风后糖尿病幸存者有效管理并发症的障碍。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-01-01 DOI: 10.17712/nsj.2024.1.20230043

Hala Azhari, Jonathan Hewitt, Alexander Smith, Martin O'Neill, Terence Quinn, Jesse Dawson

{"title":"Pioglitazone and barriers to effective post-stroke comorbidity management in stroke survivors with diabetes.","authors":"Hala Azhari, Jonathan Hewitt, Alexander Smith, Martin O'Neill, Terence Quinn, Jesse Dawson","doi":"10.17712/nsj.2024.1.20230043","DOIUrl":"10.17712/nsj.2024.1.20230043","url":null,"abstract":"Objectives: To explore the barriers preventing pioglitazone use in stroke survivors and primary and secondary stroke care services.Methods: A qualitative grounded theory approached design was used to assess post-stroke diabetes treatments and to assess clinical applicability of pioglitazone as a preventive treatment to minimize its side effects (SEs) associated. Three focus groups were established with 48 participants from Scotland and Wales health board centers during January 2019 to July 2022.Results: A qualitative grounded theory approached design was used to assess post-stroke diabetes treatments and to assess clinical applicability of pioglitazone as a preventive treatment to minimize its SEs associated. Three focus groups were established with 48 participants from Scotland and Wales health board centers during January 2019 to July 2022.Conclusion: These strategies might allow greater treatment adherence by stroke survivors and increased confidence of the health care professionals in their practice. The findings suggest that further research will be needed to facilitate wider usage of pioglitazone in treating people with stroke and health education is necessitate when using diabetes drugs post-stroke.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 1","pages":"44-50"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827012/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139403754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical trial in pregnant women addresses detection of heart disorder in the fetus. 对孕妇进行临床试验，以检测胎儿的心脏疾病。

IF 0.9 4区医学

Neurosciences Pub Date : 2024-01-01

引用次数: 0

Effects of decompressive craniectomy combined with edaravone on postoperative neurological functions and hemodynamics of patients with severe traumatic brain injury. 颅骨减压术联合依达拉奉对严重脑外伤患者术后神经功能和血液动力学的影响。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-01-01 DOI: 10.17712/nsj.2024.1.20230057

Xinjing Yang

{"title":"Effects of decompressive craniectomy combined with edaravone on postoperative neurological functions and hemodynamics of patients with severe traumatic brain injury.","authors":"Xinjing Yang","doi":"10.17712/nsj.2024.1.20230057","DOIUrl":"10.17712/nsj.2024.1.20230057","url":null,"abstract":"Objectives: To assess the effects of decompressive craniectomy combined with edaravone on the postoperative neurological functions and hemodynamics of patients with severe traumatic brain injury (STBI).Methods: The subjects included totally 186 STBI patients admitted during January 2018 and January 2021. The random number table method was adopted to set an operation group (n=82) and a combined medication group (n=104) for the subjects. The changes of the clinical indicators were observed.Results: Compared with the operation group, the combined medication group had higher Neurobehavioral Cognitive Status Examination score, Barthel index score, total response rate and heart rate (p<0.05). Besides, by contrast to those of the operation group, the mean arterial pressure, myocardial zymogram indicators, postoperative neurological function indicators and total incidence rate of complications of the combined medication group were reduced (p<0.05). In comparison with the operation group, the combined medication group exhibited raised ipsilateral contralateral blood velocities (p<0.05). Furthermore, the combined medication group had a better postoperative 1-year prognosis than the operation group (p<0.05).Conclusion: Edaravone in combination with decompressive craniectomy benefits the postoperative improvement of neurological functions of STBI patients, effectively stabilizes the hemodynamics, induces few complications and improves the prognosis.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 1","pages":"25-31"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139403750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quitting smoking cuts your risk of developing type 2 diabetes by 30-40. 戒烟可将罹患 2 型糖尿病的风险降低 30-40。

IF 0.9 4区医学

Neurosciences Pub Date : 2024-01-01

引用次数: 0

Outcomes and complications of patients with cerebral venous thrombosis: a retrospective study. 脑静脉血栓患者的预后和并发症：一项回顾性研究。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-01-01 DOI: 10.17712/nsj.2024.1.20230050

Mosaad O Almegren, Saleh H Alharbi, Turki A Alshuaibi, Mohammed M Almansour, Khalid A Alharbi, Bader Al Rawahi, Abdulmajeed K Al Balushi, Abdulrahman A Alraizah, Farjah H Alqahtani

{"title":"Outcomes and complications of patients with cerebral venous thrombosis: a retrospective study.","authors":"Mosaad O Almegren, Saleh H Alharbi, Turki A Alshuaibi, Mohammed M Almansour, Khalid A Alharbi, Bader Al Rawahi, Abdulmajeed K Al Balushi, Abdulrahman A Alraizah, Farjah H Alqahtani","doi":"10.17712/nsj.2024.1.20230050","DOIUrl":"10.17712/nsj.2024.1.20230050","url":null,"abstract":"Objectives: To assess outcomes and complications of patients with cerebral venous thrombosis (CVT).Methods: This multicenter retrospective study was conducted at 2 health care centers in Saudi Arabia and Oman. Adult patients diagnosed with CVT in radiological imaging between 2006 and 2020 were included. Data were collected from medical records and analyzed using the software IBM® SPSS version 22. Neurological disability occurring after CVT was graded according to the modified Rankin scale (mRS).Results: The study included 103 patients, of which the majority (68%) were female. The mean age was 39.12±12.96 years. Two-thirds of patients received low-molecular-weight heparin (LMWH) in acute treatment, while 76% of discharged patients used warfarin. The majority of patients had no or mild neurological disability during follow-up, and 6 patients had an mRS score ≥3, implying significant neurological disability. There were 55 patients (52.3%) who had complications from CVT, including seizures in 17 (16.5%) patients and one mortality. Follow-up imaging of 55 patients showed complete thrombus resolution in 20 patients (36%).Conclusion: Anticoagulation is the mainstay treatment for CVT patients. Approximately half of patients experience complications. Prospective studies are needed to assess the long-term neurological outcomes in such patients.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 1","pages":"32-36"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827010/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139403753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0