Neurosciences最新文献_第10页

Antibiogram data of urinary tract infection in spinal cord injury patients in an outpatient setting. 门诊脊髓损伤患者尿路感染的抗生素图谱数据。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-01-01 DOI: 10.17712/nsj.2024.1.20230063

Saeed Alshahri, Abdullah Alghaiheb, Abdullah Alanazi, Sultanah Alshammari, Abdullah Alomair

{"title":"Antibiogram data of urinary tract infection in spinal cord injury patients in an outpatient setting.","authors":"Saeed Alshahri, Abdullah Alghaiheb, Abdullah Alanazi, Sultanah Alshammari, Abdullah Alomair","doi":"10.17712/nsj.2024.1.20230063","DOIUrl":"10.17712/nsj.2024.1.20230063","url":null,"abstract":"Objectives: To establish antibiogram data for patients with spinal cord injury (SCI) that would help differentiate the organisms commonly present depending on the voiding method and antibiotic sensitivity for empirical treatment.Methods: A total of 499 urine culture results were obtained from 151 SCI patients with symptomatic urinary tract infection (UTI) with significant bacteriuria and pyuria with more than 10 white blood cells per high power field. The voiding method was categorized as follows: self-intermittent catheterization (SIC), suprapubic catheter (SPC), Foley catheter, condom catheter, or voiding freely.Results: The demographic data were as follows: male, n=124 (82.2%); female, n=27 (17.8%); mean age, 39; paraplegic n=105 (69.5%); and tetraplegic, n=45 (29.8%). The SIC was the most common voiding method (n=64, 42.3%), followed by Foley catheter (n=39, 25.8%). Escherichia coli was the most common organism overall (29%) and more frequent in patients using SIC as the voiding method. Proteus mirabilis was present more frequently in patients using SPC (33%), and Klebsiella pneumoniae in voiding freely cultures (30%). Antibiotic sensitivity was as follows Gentamicin (44.1%), Nitrofurantoin (39.1%), Augmentin (33.5%), and Ciprofloxacin (31.5%).Conclusion: Increased preference of the local population to foley catheter as a voiding method which needs to be investigated more. The type of voiding methods in patients with SCI results in different common causative organisms of UTI. Ciprofloxacin resistance profile increased overall except in patients voiding with SPC. Nitrofurantoin is the most overall sensitive oral antibiotic in our sample followed by Augmentin then Cefuroxime.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 1","pages":"57-62"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827016/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139403743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial Message. 编辑信息。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-01-01 DOI: 10.17712/nsj.2024.1.20230200

Waleed Khoja, Khalid Hundallah, Mashael Al-Askar

引用次数: 0

Hemorrhagic fever with renal syndrome and reversible splenial lesion syndrome. 伴有肾综合征和可逆性脾损伤综合征的出血热。

IF 1.2 4区医学

Neurosciences Pub Date : 2023-10-01 DOI: 10.17712/nsj.2023.4.202300133

Xulei Zhang, Yimin Ma, Renchen Cai, Zhenguo Qiao

引用次数: 0

The role of MicroRNA as a potential diagnostic and prognostic biomarker for cerebral aneurysms. 微小核糖核酸作为脑动脉瘤潜在诊断和预后生物标志物的作用。

IF 1.2 4区医学

Neurosciences Pub Date : 2023-10-01 DOI: 10.17712/nsj.2023.4.20230028

Hosam M Al-Jehani, Alaa N Turkistani, Majd M Alrayes, May A AlHamid, Arwa S AlShamikh, Zhra M Al Sadah, Faisal M Alabbas, Cyril Cyrus, Amein K Al-Ali

{"title":"The role of MicroRNA as a potential diagnostic and prognostic biomarker for cerebral aneurysms.","authors":"Hosam M Al-Jehani, Alaa N Turkistani, Majd M Alrayes, May A AlHamid, Arwa S AlShamikh, Zhra M Al Sadah, Faisal M Alabbas, Cyril Cyrus, Amein K Al-Ali","doi":"10.17712/nsj.2023.4.20230028","DOIUrl":"10.17712/nsj.2023.4.20230028","url":null,"abstract":"Objectives: To identify the dysregulated functional miRNAs, miRNA-16, miRNA-143, and miRNA-200 as potential biomarkers of cerebral aneurysms(CAs) to aid in diagnosis and prognosis.Methods: This is a prospective case-control study conducted among patients with CA. All patients' computed tomography angiography (CTA) and interventional angiogram were assessed and studied. The miRNAs were isolated and quantified from peripheral blood samples and the expression profiling was done using TaqMan chemistry on Real-Time PCR.Results: A total of 37 samples were included. Three cases had double aneurysms and 10 cases presented with aneurysmal rupture. miRNA-16, miRNA-143, and miRNA-200 were upregulated with an absolute fold-change of >8 in the CA group in comparison to controls (p<0.05). miRNA-200 showed double expression in patients with single aneurysm. A statically significant increase was observed in the expression of miRNA-143 in patients who had an aneurysmal rupture with p<0.05. Diabetic patients showed an obvious increase in miRNA-200 (13.03 folds) and miRNA-16 (26.82 folds) expression. Also, there was a notable elevation in miRNA-16, miRNA-143, and miRNA-200 in patients who had hypertension in comparison to those who did not.Conclusion: miRNA-16, miRNA-143, and miRNA-200 showed statically significant higher expression among cases with cerebral aneurysms in comparison to controls. Thus, these preliminary results of miRNAs biomarkers are promising future tool to be used for aneurysmal screening.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"28 4","pages":"250-257"},"PeriodicalIF":1.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41237267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative effectiveness of dual antiplatelet therapy versus monotherapy in patients with ischemic stroke. 双抗血小板治疗与单药治疗缺血性脑卒中患者的疗效比较。

IF 1.2 4区医学

Neurosciences Pub Date : 2023-10-01 DOI: 10.17712/nsj.2023.4.20230021

Rahmah A Algarni, Abdulhamid A Althagafi, Samah Alshehri, Mohannad Alshibani, Omar Alshargi

{"title":"Comparative effectiveness of dual antiplatelet therapy versus monotherapy in patients with ischemic stroke.","authors":"Rahmah A Algarni, Abdulhamid A Althagafi, Samah Alshehri, Mohannad Alshibani, Omar Alshargi","doi":"10.17712/nsj.2023.4.20230021","DOIUrl":"10.17712/nsj.2023.4.20230021","url":null,"abstract":"Objectives: To compare the effectiveness of aspirin-clopidogrel dual antiplatelet therapy (DAPT) with aspirin or clopidogrel antiplatelet monotherapy (AM) in patients with ischemic stroke.Methods: It was a single-center, retrospective cross-sectional study of medical records of ischemic stroke patients admitted at King Abdulaziz University Hospital between January 2015 and October 2019. The primary endpoints were ischemic stroke recurrence, rehospitalization, and all-cause mortality between DAPT and AM. Kaplan-Meier and Cox proportional hazard analyses were employed in univariate and multivariate time-to-event analyses.Results: The median time to recurrence of ischemic stroke was 15.0 months (95% confidence interval [CI], 8.586-23.01) for DAPT and 20.4 months (95% CI, 9.872-30.928) for the AM. The median survival time until all-cause mortality was 8.0 months (95% CI, 2.893-13.107) for DAPT and 14.1 months (95% CI, 8.173-19.97) for the AM. No statistically significant reductions in the instantaneous risks of recurrence (hazard ratio [HR], 1.27; 95% CI, 0.59-2.72; p=0.54), re-hospitalization (HR, 0.95; 95% CI, 0.59-1.48; p= 0.77), and mortality (HR, 1.04; 95% CI, 0.48-2.26; p=0.92) were found between the DAPT and AM groups.Conclusion: The DAPT was not superior to AM in reducing recurrence and mortality events in patients with ischemic stroke. Rehospitalization due to the sequelae of the composite of stroke, angina, and myocardial infarction was higher in the DAPT group.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"28 4","pages":"220-226"},"PeriodicalIF":1.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41237254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reccurent guillain barré syndrome after COVID-19. 新冠肺炎后格林-巴利综合征复发。

IF 1.2 4区医学

Neurosciences Pub Date : 2023-10-01 DOI: 10.17712/nsj.2023.4.20230012

Svetlana D Miletic Drakulic, Snezana R Lazarevic, Ivana P Miloradovic, Vladimir S Jankovic

引用次数: 0

Erratum. 勘误表。

IF 0.9 4区医学

Neurosciences Pub Date : 2023-10-01 DOI: 10.17712/nsj.2023.4.20234444

引用次数: 0

IF 1.2 4区医学

Neurosciences Pub Date : 2023-10-01 DOI: 10.17712/nsj.2023.4.20230026

Alaa Eskandrani, Eman Almusallam, Asmaa Alenizi, Safiyyah Asiri, Fawziah Bamogaddam, Majed Alhameed, Mubarak M Aldosari

{"title":"Health related quality of life in a Saudi population of patients with epilepsy.","authors":"Alaa Eskandrani, Eman Almusallam, Asmaa Alenizi, Safiyyah Asiri, Fawziah Bamogaddam, Majed Alhameed, Mubarak M Aldosari","doi":"10.17712/nsj.2023.4.20230026","DOIUrl":"10.17712/nsj.2023.4.20230026","url":null,"abstract":"Objectives: To assess the quality of life for epilepsy patients in Saudi Arabia. Epilepsy, one of the most prevalent chronic neurological conditions in the world, frequently results in a low quality of life.Methods: This cross-sectional study analyzed data between September 2020 and September 2021 from 102 adult patients with epilepsy in outpatient clinics department of Epilepsy Program at King Fahad Medical City compared it to 108 healthy controls during the same study period. Sociodemographics and clinical data were gathered using the Arabic version of the Rand 36-Item Short Form Survey (SF-36) questionnaire and the Quality of Life in Epilepsy Inventory (QOLIE-31).Results: Patients with epilepsy had lower SF-36 scores when compared to the control for role limitation due to physical health, role limitations due to emotional health, and general health. The QOLIE-31 revealed that gender was associated with energy/fatigue (p=0.028), medication effect (p=0.016), and social function (p=0.003); only social functioning showed a significant association (p=0.023) with employment.Conclusion: Quality of life for patients with epilepsy was found to be significantly impacted in Saudi Arabia. Certain factors found in this study differentiate it from data that has already been released. This might be due to Arab differences in family support as well as cultural and religious beliefs.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"28 4","pages":"234-242"},"PeriodicalIF":1.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827025/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41237256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Higher education student perceptions regarding the practice of telemental health services in Kingdom of Saudi Arabia. 沙特阿拉伯王国高等教育学生对远程心理健康服务实践的看法。

IF 1.2 4区医学

Neurosciences Pub Date : 2023-10-01 DOI: 10.17712/nsj.2023.4.20230011

Bussma A Bugis, Leena Z Alzayed, Manar H Bin Helabi, Heba A Alqurashi

{"title":"Higher education student perceptions regarding the practice of telemental health services in Kingdom of Saudi Arabia.","authors":"Bussma A Bugis, Leena Z Alzayed, Manar H Bin Helabi, Heba A Alqurashi","doi":"10.17712/nsj.2023.4.20230011","DOIUrl":"10.17712/nsj.2023.4.20230011","url":null,"abstract":"Objectives: To study higher education student perceptions regarding the practice of telemental health services in Saudi Arabia.Methods: The study conducted a cross-sectional descriptive design through an online self-administered survey. The targeted number of responses was set to at least 385 convenience-sample students who were enrolled in different degree programs at the selected university for the Spring 2022 semester. Data collection was done during March 2022.Results: The sample population was 401 eligible responses. Most respondents Most respondents were from Riyadh (39.15%), females (66.33%), single (64.83%) at the time of data collection. Forty-five percent of participants did not use any telemental health services in the past. Moreover, 34.41% of the participants reported that they preferred to use mixed methods of mental services that combined face-to-face and distanced interactions. Telemental services that can be provided based on students' perceptions were consultations (75.81%), followed by education and promotion (64.33%). Almost half of the participants reported that the internet and culture are among the factors that have shaped their perceptions of telemental health in Saudi Arabia, while the least important factor was their experience with providers.Conclusion: The current study showed that the higher education students perceived telemental health positively and were willing to use telemental health in the future; in addition, the most essential technologies related to telemental health services were videoconferences, audio-visuals, and telephones.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"28 4","pages":"227-233"},"PeriodicalIF":1.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41237258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Robust analysis challenges theory that depression and anxiety increase cancer risk. 稳健的分析挑战了抑郁症和焦虑会增加癌症风险的理论。

IF 0.9 4区医学

Neurosciences Pub Date : 2023-10-01

引用次数: 0