Neurosciences最新文献_第8页

Comment on: Diagnosis of autoimmune epilepsy requires documentation of a causal relationship between the immune response and seizures. 评论：诊断自身免疫性癫痫需要证明免疫反应与癫痫发作之间存在因果关系。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01 DOI: 10.17712/nsj.2024.2.20230126

S Zarrouk, Sounira Mehri, Josef Finsterer

引用次数: 0

WHO prequalifies a second malaria vaccine, a significant milestone in prevention of the disease. 世卫组织对第二种疟疾疫苗进行资格预审，这是预防疟疾的一个重要里程碑。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01

引用次数: 0

Urgent action needed to protect children and prevent the uptake of e-cigarettes. 需要采取紧急行动保护儿童，防止他们吸食电子烟。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01

引用次数: 0

Risk factors for cerebral edema following aneurysm clipping in patients with aneurysmal subarachnoid hemorrhage. 动脉瘤性蛛网膜下腔出血患者动脉瘤夹闭术后出现脑水肿的风险因素。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01 DOI: 10.17712/nsj.2024.2.20230082

Shifeng Xu, Baodong Chen, Hui Qi, Hongbin Liu

{"title":"Risk factors for cerebral edema following aneurysm clipping in patients with aneurysmal subarachnoid hemorrhage.","authors":"Shifeng Xu, Baodong Chen, Hui Qi, Hongbin Liu","doi":"10.17712/nsj.2024.2.20230082","DOIUrl":"10.17712/nsj.2024.2.20230082","url":null,"abstract":"Objectives: To investigate the factors that contribute to the development of cerebral edema after aneurysm clipping in individuals with aneurysmal subarachnoid hemorrhage (aSAH).Methods: A total of 232 patients with aSAH caused by rupture and treated with aneurysm clipping were included in the retrospective analysis of clinical data. Postoperatively, the participants were categorized into two groups based on the presence or absence of cerebral edema: a complication group (n=33) and a non-complication group (n=199).A comparison was made between the overall data of the 2 groups.Results: In the complication group, there were higher proportions of patients experiencing recurrent bleeding, aneurysm in the posterior circulation, Fisher grade III-IV, World Federation of Neurosurgical Societies (WFNS) grade II, Hunt-Hess grade III-IV, concomitant hypertension, duration from onset to operation ≥12 h, and concomitant hematoma compared to the non-complication group (p<0.05). Cerebral edema after aneurysm clipping was associated with several risk factors including repeated bleeding, aneurysm in the back of the brain, Fisher grade III-IV, WFNS grade II, Hunt-Hess grade III-IV, simultaneous high blood pressure and hematoma, and a duration of at least 12 hours from the start of symptoms to the surgical procedure (p<0.05).Conclusion: In patients with aSAH, the risk of cerebral edema after aneurysm clipping is increased by recurrent bleeding, aneurysm in the posterior circulation, Fisher grade III-IV, WFNS grade II, Hunt-Hess grade III-IV, concomitant hypertension and hematoma, and duration of ≥12 h from onset to operation.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 2","pages":"90-95"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic effectiveness of deep learning-based MRI in predicting multiple sclerosis: A meta-analysis. 基于深度学习的磁共振成像在预测多发性硬化症方面的诊断效果：荟萃分析

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01 DOI: 10.17712/nsj.2024.2.20230103

Tareef S Daqqaq, Ayman S Alhasan, Hadeel A Ghunaim

{"title":"Diagnostic effectiveness of deep learning-based MRI in predicting multiple sclerosis: A meta-analysis.","authors":"Tareef S Daqqaq, Ayman S Alhasan, Hadeel A Ghunaim","doi":"10.17712/nsj.2024.2.20230103","DOIUrl":"10.17712/nsj.2024.2.20230103","url":null,"abstract":"Objectives: The brain and spinal cord, constituting the central nervous system (CNS), could be impacted by an inflammatory disease known as multiple sclerosis (MS). The convolutional neural networks (CNN), a machine learning method, can detect lesions early by learning patterns on brain magnetic resonance image (MRI). We performed this study to investigate the diagnostic performance of CNN based MRI in the identification, classification, and segmentation of MS lesions.Methods: PubMed, Web of Science, Embase, the Cochrane Library, CINAHL, and Google Scholar were used to retrieve papers reporting the use of CNN based MRI in MS diagnosis. The accuracy, the specificity, the sensitivity, and the Dice Similarity Coefficient (DSC) were evaluated in this study.Results: In total, 2174 studies were identified and only 15 articles met the inclusion criteria. The 2D-3D CNN presented a high accuracy (98.81, 95% CI: 98.50-99.13), sensitivity (98.76, 95% CI: 98.42-99.10), and specificity (98.67, 95% CI: 98.22-99.12) in the identification of MS lesions. Regarding classification, the overall accuracy rate was significantly high (91.38, 95% CI: 83.23-99.54). A DSC rate of 63.78 (95% CI: 58.29-69.27) showed that 2D-3D CNN-based MRI performed highly in the segmentation of MS lesions. Sensitivity analysis showed that the results are consistent, indicating that this study is robust.Conclusion: This metanalysis revealed that 2D-3D CNN based MRI is an automated system that has high diagnostic performance and can promptly and effectively predict the disease.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 2","pages":"77-89"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PSYCHEDELIC PSILOCYBIN-ASSISTED THERAPY REDUCES DEPRESSIVE SYMPTOMS IN ADULTS WITH CANCER AND DEPRESSION. 迷幻药迷幻药辅助疗法可减轻癌症和抑郁症成人患者的抑郁症状。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01

引用次数: 0

A review of the gastrointestinal, olfactory, and skin abnormalities in patients with Parkinson's disease. 回顾帕金森病患者的胃肠道、嗅觉和皮肤异常。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-01-01 DOI: 10.17712/nsj.2024.1.20230062

Mohannad A Almikhlafi

引用次数: 0

Evaluation of gene-gene interaction between the interleukin (IL)-2 and IL-2RA gene polymorphisms in schizophrenia patients in the Turkish Population. 评估土耳其人群中精神分裂症患者的白细胞介素（IL）-2 和 IL-2RA 基因多态性之间的基因-基因相互作用。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-01-01 DOI: 10.17712/nsj.2024.1.20230075

Kursat Ozdilli, Hasan Mervan Aytac, Fatima Ceren Tuncel, Yasemin Oyaci, Mustafa Pehlivan, Sacide Pehlivan

{"title":"Evaluation of gene-gene interaction between the interleukin (IL)-2 and IL-2RA gene polymorphisms in schizophrenia patients in the Turkish Population.","authors":"Kursat Ozdilli, Hasan Mervan Aytac, Fatima Ceren Tuncel, Yasemin Oyaci, Mustafa Pehlivan, Sacide Pehlivan","doi":"10.17712/nsj.2024.1.20230075","DOIUrl":"10.17712/nsj.2024.1.20230075","url":null,"abstract":"Objectives: To evaluate the genetic polymorphisms in IL-2 and IL-2RA genes in schizophrenia (SCZ) patients by comparing them with healthy controls.Methods: A sample of 127 patients with SCZ and 100 healthy volunteers were included in the case-control study. These individuals were consecutively selected from the Malazgirt State Hospital Psychiatry Outpatient Clinic in Mus, Turkey, over the three months from October 2020 to December 2020. The Structured Clinical Interview for DSM-5 Disorders, Clinician Version (SCID-5-CV) was used to confirm the diagnosis according to the DSM-5 criteria. In addition, polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to determine gene polymorphisms from DNA material.Results: Our findings indicated significant differences in the IL-2 genotype and allele frequencies between SCZ patients and the healthy control group. Specifically, the frequency of the homozygous GG genotype was notably higher in SCZ patients compared to the control group. Conversely, when comparing the IL-2RA genotype and allele frequencies of SCZ patients with the control group, no statistically significant differences were observed between the 2 groups. When compared to individuals with other genotypes, interaction analysis indicated that carriers of the GG/AG (IL-2/IL-2RA) genotype demonstrated a significantly increased risk of SCZ.Conclusion: In light of the analyses, our study indicates that while the IL-2 genotype polymorphism may be considered a risk factor for developing SCZ, the IL-2RA variant was not associated with SCZ among Turkish patients.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 1","pages":"51-56"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139403751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of radiology modalities in diagnosing and characterizing brain disorders. 放射学模式在诊断和描述脑部疾病方面的有效性。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-01-01 DOI: 10.17712/nsj.2024.1.20230048

Sadeem Aljahdali, Ghofran Azim, Waad Zabani, Saeed Bafaraj, Jaber Alyami, Ahmed Abduljabbar

{"title":"Effectiveness of radiology modalities in diagnosing and characterizing brain disorders.","authors":"Sadeem Aljahdali, Ghofran Azim, Waad Zabani, Saeed Bafaraj, Jaber Alyami, Ahmed Abduljabbar","doi":"10.17712/nsj.2024.1.20230048","DOIUrl":"10.17712/nsj.2024.1.20230048","url":null,"abstract":"Objectives: To observe the accuracy of Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) scans in evaluating neurological disorders.Methods: This retrospective research used CT or MRI to diagnose and characterize brain disorders. Patients' records suffering from neurological disorders were considered eligible for inclusion, regardless of the time of appearance of symptoms, the severity of their symptoms, or their final clinical diagnosis. The exclusion criteria for this study involved patients who did not undergo either a CT or MRI scan. A chi-square test was performed to observe the association between the study variables. A total of 3155 cases were analyzed.Results: The most prevalent comorbid was dyslipidemia 670 (21.6%) followed by hypertension 548 (17.6%). Overall brain disorders were confirmed in 2426 (77%) patients. It was observed that half of the patients 1543 (48.9%) were diagnosed with stroke. It was found that the accuracy of CT and MRI was 78% and 74% respectively. The association of modalities, patient type, and gender with the confirmation of diseases was not found significant (p=>0.05).Conclusion: Our study revealed that CT and MRI were accurate by more than 75% and no difference was between both techniques to detect neurological disorders.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 1","pages":"37-43"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139403749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Working under the sun causes 1 in 3 deaths from non-melanoma skin cancer, say WHO AND ILO. 世界卫生组织和国际劳工组织表示，在阳光下工作导致每 3 人中就有 1 人死于非黑色素瘤皮肤癌。

IF 0.9 4区医学

Neurosciences Pub Date : 2024-01-01

引用次数: 0