Neurosciences最新文献_第7页

Unraveling morphology, methylation profiling, and diagnostic challenges in BRAF-Mutant pediatric glial and glioneuronal tumors. 揭示 BRAF 突变小儿神经胶质和神经胶质细胞肿瘤的形态学、甲基化分析和诊断难题。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-07-01 DOI: 10.17712/nsj.2024.3.20230108

Murad Alturkustani

{"title":"Unraveling morphology, methylation profiling, and diagnostic challenges in BRAF-Mutant pediatric glial and glioneuronal tumors.","authors":"Murad Alturkustani","doi":"10.17712/nsj.2024.3.20230108","DOIUrl":"10.17712/nsj.2024.3.20230108","url":null,"abstract":"Objectives: To elucidate the relationship between DNA methylation profiling (DMP) and pathological diagnosis (PD) in pediatric glial and glioneuronal tumors with B-Raf proto-oncogene, serine/threonine kinase (BRAF) mutations, addressing their diagnostic challenges.Methods: This retrospective study, conducted in Saudi Arabia, analyzed 47 cases from the Children's Brain Tumor Network online database using scanned images, next-generation sequencing data, and methylation profiles processed using the Heidelberg methylation brain tumor classifiers v12.5 and v12.8. The data was last access on 10 November 2023.Results: The highest prevalence of BRAF mutations was observed in pilocytic astrocytoma and ganglioglioma. The DMP was consistent with PD in 23 cases, but discrepancies emerged in others, including diagnostic changes in diffuse leptomeningeal glioneuronal tumor and polymorphous low-grade neuroepithelial tumor of the young. A key inconsistency appeared between a pilocytic astrocytoma MC and a glioneuronal tumor PD. Two high-grade astrocytomas were misclassified as pleomorphic xanthoastrocytomas. Additionally, low variant allelic frequency in gangliogliomas likely contributed to misclassifications as control in 5 cases.Conclusion: This study emphasized the importance of integrating DMP with PD in diagnosing pediatric glial and glioneuronal tumors with BRAF mutations. Although DMP offers significant diagnostic insights, its limitations, particularly in cases with low tumor content, necessitate cautious interpretation, as well as its use as a complementary diagnostic tool, rather than a definitive method.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"168-176"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

More than what meets the eye in COVID-19 critical illness: A case report of bilateral femoral neuropathy due to psoas hematomas. COVID-19危重症患者的病症远不止这些：腰肌血肿导致双侧股神经病变的病例报告。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01 DOI: 10.17712/nsj.2024.2.20230072

Ameerah K Alsaqobi, Brouj A Miskin, Biju Gopinath, Ghada Elgohary

{"title":"More than what meets the eye in COVID-19 critical illness: A case report of bilateral femoral neuropathy due to psoas hematomas.","authors":"Ameerah K Alsaqobi, Brouj A Miskin, Biju Gopinath, Ghada Elgohary","doi":"10.17712/nsj.2024.2.20230072","DOIUrl":"10.17712/nsj.2024.2.20230072","url":null,"abstract":"Bilateral femoral neuropathy is rare, especially that caused by bilateral compressive iliopsoas, psoas, or iliacus muscle hematomas. We present a case of bilateral femoral neuropathy due to spontaneous psoas hematomas developed during COVID-19 critical illness. A 41-year-old patient developed COVID-19 pneumonia, and his condition deteriorated rapidly. A decrease in the hemoglobin level prompted imaging studies during his intensive care unit (ICU) stay. Bilateral psoas hematomas were identified as the source of bleeding. Thereafter, the patient complained of weakness in both upper and lower limbs and numbness in the lower limb. He was considered to have critical illness neuropathy and was referred to rehabilitation. Electrodiagnostic testing suggested bilateral femoral neuropathy because of compression due to hematomas developed during the course of his ICU stay. The consequences of iliopsoas hematomas occurring in the critically ill can be catastrophic, ranging from hemorrhagic shock to severe weakness, highlighting the importance of recognizing this entity.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 2","pages":"133-138"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Review of the spectrum of tuberous sclerosis complex: The Saudi Arabian Experience. 回顾结节性硬化症复合病谱：沙特阿拉伯的经验。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01 DOI: 10.17712/nsj.2024.2.20230061

Mohammed Almuqbil, Waad Aldoohan, Sara Alhinti, Nora Almahmoud, Imad Abdulmajeed, Rayan Alkhodair, Amna Kashgari, Duaa Baarmah, Waleed Altwaijri, Ahmad Alrumayyan

{"title":"Review of the spectrum of tuberous sclerosis complex: The Saudi Arabian Experience.","authors":"Mohammed Almuqbil, Waad Aldoohan, Sara Alhinti, Nora Almahmoud, Imad Abdulmajeed, Rayan Alkhodair, Amna Kashgari, Duaa Baarmah, Waleed Altwaijri, Ahmad Alrumayyan","doi":"10.17712/nsj.2024.2.20230061","DOIUrl":"10.17712/nsj.2024.2.20230061","url":null,"abstract":"Objectives: To determine the prevalence of tuberous sclerosis complex (TSC) in the paediatric Saudi population and to characterise the range of clinical symptoms, neurocutaneous findings, neuroimaging results, and complications of the disease.Methods: A total of 61 genetically confirmed TSC patients from the National Guard Health Affairs (NGHA) in Saudi Arabia were the subject of this retrospective descriptive analysis. The data were presented using descriptive measures.Results: The mean age at diagnosis was found to be 4.9 years. Subependymal nodules (86.9%), numerous cortical tubers and/or radial migration lines (63.9%), and hypomelanotic macules (63.9%) were the 3 most common significant criteria. The vast majority (86.9%) of those diagnosed had epilepsy, of which 50% were considered medically intractable. Nearly half of our subjects underwent genetic testing, which revealed that TSC2 predominated over TSC1. Symptoms of Tuberous Sclerosis Complex-Associated Neuropsychiatric Disorders (TAND) were present in 66.7% of TSC1 patients and 73.9% of TSC2 patients.Conclusion: The findings of this study demonstrate that the clinical spectrum of TSC among Saudi children is consistent with the body of existing literature. The TSC2 was more prevalent than TSC1. The most frequent signs were cutaneous and neurological. Monitoring TSC patients regularly is crucial to identify any issues as soon as possible.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 2","pages":"113-121"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sporadic subependymal giant cell astrocytoma with somatic TSC2 mutation: A case report. 散发性巨细胞星形细胞瘤伴有体细胞TSC2突变：病例报告。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01 DOI: 10.17712/nsj.2024.2.20230089

Ali H Alassiri, Turki M Alfayea, Tariq I Aljared, Khaled R Alenezi

{"title":"Sporadic subependymal giant cell astrocytoma with somatic TSC2 mutation: A case report.","authors":"Ali H Alassiri, Turki M Alfayea, Tariq I Aljared, Khaled R Alenezi","doi":"10.17712/nsj.2024.2.20230089","DOIUrl":"10.17712/nsj.2024.2.20230089","url":null,"abstract":"Subependymal giant cell astrocytoma (SEGA) is a rare circumscribed astrocytic glioma that occurs in approximately 25% of all tuberous sclerosis (TSC) cases. Herein, we discuss an atypical presentation of SEGA, including the genetic alterations, impact on clinical presentation, and the determinants of each medical and surgical treatment option. A 14-year-old girl presented with intermittent headache and a right intraventricular mass originating near the foramen of Monro. The tumor's proximity to critical structures necessitated maximum safe resection, which improved her symptoms. Histological findings indicated SEGA, and genetic sequencing revealed a TSC2 mutation. However, complete clinical and radiological evaluations failed to reveal TSC. Two months later, a new subependymal nodule was incidentally found. She had a recurrent left occipital horn lesion and diffuse smooth leptomeningeal enhancement with no spine drop metastases. She was administered everolimus as the tumor was considered unresectable. Subsequent imaging revealed a reduction in both residual and new lesions.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 2","pages":"139-143"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The protective effect of Astaxanthin on scopolamine - induced Alzheimer's model in mice. 虾青素对东莨菪碱诱导的阿尔茨海默氏症小鼠模型的保护作用。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01 DOI: 10.17712/nsj.2024.2.20230060

Rania Magadmi, Sara Nassibi, Fatemah Kamel, Aziza R Al-Rafiah, Duaa Bakhshwin, Maha Jamal, Mohammed Alsieni, Abdulhadi S Burzangi, M A F Zaher, Mohammed Bendary

{"title":"The protective effect of Astaxanthin on scopolamine - induced Alzheimer's model in mice.","authors":"Rania Magadmi, Sara Nassibi, Fatemah Kamel, Aziza R Al-Rafiah, Duaa Bakhshwin, Maha Jamal, Mohammed Alsieni, Abdulhadi S Burzangi, M A F Zaher, Mohammed Bendary","doi":"10.17712/nsj.2024.2.20230060","DOIUrl":"10.17712/nsj.2024.2.20230060","url":null,"abstract":"Objectives: To investigate the fundamental mechanisms of the neuroprotective impact of Astaxanthin (AST) in a mouse model of Alzheimer's disease (AD) induced by scopolamine.Methods: This research constituted an in vivo animal study encompassing 36 adult male mice, divided into 6 groups: Control, 100 mg/kg AST, 2 mg/kg scopolamine (AD group), 100 mg/kg AST+2 mg/kg scopolamine, 3 mg/kg galantamine+2 mg/kg scopolamine, and 100 mg/kg AST+3 mg/kg galantamine+2 mg/kg scopolamine. After 14 days, the mice's short-term memory, hippocampus tissue, oxidative and inflammatory markers were evaluated.Results: The AST demonstrated a beneficial influence on short-term memory and a reduction in acetylcholinesterase activity in the brain. It exhibited neuroprotective and anti-amyloidogenic properties, significantly decreased pro-inflammatory markers and oxidative stress, and reversed the decline of the Akt-1 and phosphorylated Akt pathway, a crucial regulator of abnormal tau. Furthermore, AST enhanced the effect of galantamine in reducing inflammation and oxidative stress.Conclusion: The findings indicate that AST may offer therapeutic benefits against cognitive dysfunction in AD. This is attributed to its ability to reduce oxidative stress, control neuroinflammation, and enhance Akt-1 and pAkt levels, thereby underscoring its potential in AD treatment strategies.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 2","pages":"103-112"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epilepsia partialis continua: A review. 癫痫部分性持续状态：综述。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01 DOI: 10.17712/nsj.2024.2.20230074

Osama Y Muthaffar, Anas S Alyazidi

{"title":"Epilepsia partialis continua: A review.","authors":"Osama Y Muthaffar, Anas S Alyazidi","doi":"10.17712/nsj.2024.2.20230074","DOIUrl":"10.17712/nsj.2024.2.20230074","url":null,"abstract":"Epilepsia partialis continua (EPC) is a rare type of focal motor seizure characterized by continuous, involuntary muscle contractions in a specific part of the body. These contractions usually involve rhythmic, twitching movements and can last for several hours to days. The seizures are usually limited to one part of the body and can be clonic or dystonic. EPC can affect people of all ages but is more common in children and adolescents. The pathophysiology of EPC is complex and depends on the cause. There are several possible causes of EPC including structural brain abnormalities, infections, metabolic and genetic disorders, inflammatory conditions, traumatic brain injury, and vascular causes. The work-up of EPC includes electroencephalography (EEG), magnetic resonance imaging (MRI) of the brain, position emission tomography (PET) scan of the brain, autoimmune antibodies, infection work-up, and metabolic and genetic work-up. The management of EPC can be challenging. Antiseizure medications (ASDs) including benzodiazepines are an integral part of the management of EPC. Immunotherapy trials are recommended in resistant cases. Epilepsy surgery is one of the effective modalities in some surgically amenable cases. This article reviews the topic of EPC and summarizes diagnostic and .treatment recommendations.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 2","pages":"71-76"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305367/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Normative parameters of the Evans Index using Computer Tomography in the Saudi population. 在沙特人口中使用计算机断层扫描测量埃文斯指数的标准参数。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01 DOI: 10.17712/nsj.2024.2.20230097

Soha A Alomar, Aliaa H Ghoneim

{"title":"Normative parameters of the Evans Index using Computer Tomography in the Saudi population.","authors":"Soha A Alomar, Aliaa H Ghoneim","doi":"10.17712/nsj.2024.2.20230097","DOIUrl":"10.17712/nsj.2024.2.20230097","url":null,"abstract":"Objectives: To calculate The Evans Index (EI) in normal Individuals. Ventricular enlargement is referred to as hydrocephalus. Computer tomography (CT) scans are commonly used to investigate such intracranial pathologies. The EI is an important parameter for diagnosing hydrocephalus.Methods: We included all patients who underwent Computer tomography (CT) scan of the brain that was reported as normal. The mean EI was calculated for the whole sample stratified by age, gender, and ethnicity. Patients with an initial report indicating any intracranial pathology, such as hydrocephalus, tumors, hemorrhages, or neurodegenerative disorders, were excluded.Results: A total of 1,330 brain CT scans carried out at our institution were reviewed retrospectively from August 2021 to December 2021. A total of 423 CT scans were screened after excluding 25 patients with abnormal imaging findings and 14 repeated images for the same patients. A total of 384 patients were included. The mean EI for the entire sample was 0.2550±0.0277. There was a minimal but statistically significant difference based on gender, with a mean EI of 0.2588±0.0274 for males and 0.2517±0.0276 for females (p=0.012). There was no statistically significant difference between Saudi and non-Saudi patients. EI increased progressively with age in both genders.Conclusion: Our EI values were similar to many of those reported in other countries, which supports the use of the 0.3 cutoff for the diagnosis of hydrocephalus, regardless of gender, age, or ethnicity.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 2","pages":"122-127"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemopatch^® as a primary dural sealant in cranial neurosurgery: Technical note and a retrospective study. Hemopatch® 作为颅神经外科的主要硬脑膜密封剂：技术说明和回顾性研究。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01 DOI: 10.17712/nsj.2024.2.20230109

Homoud A Aldahash, Muhammad A Ansary, Hana M Hallak, Meshari R Alhuthayl, Faisal A Alotaibi

{"title":"Hemopatch® as a primary dural sealant in cranial neurosurgery: Technical note and a retrospective study.","authors":"Homoud A Aldahash, Muhammad A Ansary, Hana M Hallak, Meshari R Alhuthayl, Faisal A Alotaibi","doi":"10.17712/nsj.2024.2.20230109","DOIUrl":"10.17712/nsj.2024.2.20230109","url":null,"abstract":"Objectives: To determine the effectiveness and safety of Hemopatch® as a primary dural sealant in preventing CSF leakage following cranial surgery. Cerebrospinal fluid (CSF) leaks occur in cranial operations and are associated with significant patient burden and expense. The use of Hemopatch® as a dural sealant in cranial neurosurgical procedures is described and analyzed in this study.Methods: Data were retrospectively collected from all patients who underwent a craniotomy for various neurosurgical indications where Hemopatch® was used as the primary dural sealant between June 2017 and June 2022. Infection and CSF leak were the main indicators evaluated after surgery.Results: A total of 119 consecutive patients met our inclusion criteria. The median was age 41.5 years, and 52.5% were female. The mean follow-up period was 2.3 years (7 months to 6 years). There were 110 (92.44%) supratentorial and 9 (7.56%) infratentorial craniotomies. Postoperative CSF leak was reported in 2 patients (1.68%), one in each cohort. Postoperative infection occurred in one patient (0.84%).Conclusion: The results suggest that using Hemopatch® as a dural sealant in cranial surgery is effective and safe. After supra-/infratentorial craniotomies, the rate of postoperative adverse events in our sample was within the range of known surgical revision rates. Future randomized clinical studies are required to confirm our encouraging findings.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 2","pages":"128-132"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305368/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurophobia: challenges and solutions. 神经恐惧症：挑战与解决方案。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01 DOI: 10.17712/nsj.2024.2.20230127

Tarig Abkur, Zahir Satti, Daniel G Di Luca, Ibrahim Alhashyan, Hanin Algethami

引用次数: 0

Atypical meningiomas compared to other WHO Grade 2 meningiomas: Histological features and prognosis. 非典型脑膜瘤与其他世卫组织 2 级脑膜瘤的比较：组织学特征和预后。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-05-01 DOI: 10.17712/nsj.2024.2.20230091

Abdulrazag Ajlan, Saif Almeshari, Sarah Basindwah, Majed Aljohani, Yazed Alharbi, Fahad Aldhowaihy, Hisham Alkhaldi, Ashwag Alqurashi

{"title":"Atypical meningiomas compared to other WHO Grade 2 meningiomas: Histological features and prognosis.","authors":"Abdulrazag Ajlan, Saif Almeshari, Sarah Basindwah, Majed Aljohani, Yazed Alharbi, Fahad Aldhowaihy, Hisham Alkhaldi, Ashwag Alqurashi","doi":"10.17712/nsj.2024.2.20230091","DOIUrl":"10.17712/nsj.2024.2.20230091","url":null,"abstract":"Objectives: To study each atypical feature in atypical meningioma versus other grade 2 meningiomas and its possible relation to recurrence.Methods: This is a retrospective study of patients with WHO grade 2 meningioma operated in our institution between 01/2008 and 12/2020. The rate of recurrence, reoperation and readmission were recorded during the follow-up period. A statistical analysis was done to determine the significance of each pathological feature in regard to recurrence.Results: A total of 74 patients were included as WHO grade 2 meningioma with 60 (81%) patients having an AM and 14 (19%) patients with chordoid or clear cell meningioma. The mean age was 51 years±14. The most common location was meningioma abutting the frontal lobe (convexity). Major atypical features were more noted in the AM, however, there was no significant difference between AM and other types of meningioma. Increased Nuclear cytoplasmic ratio and cellularity were found significantly more in AM. The recurrence rate was 16.2%. No specific pathology feature (major or minor) nor the type of Grade 2 meningioma was significantly related to recurrence.Conclusion: The types of WHO grade 2 meningiomas have similar prognosis and recurrence rates. There is no significant difference between the atypical features in indicating a more aggressive nature or risk of recurrence in grade 2 meningiomas.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 2","pages":"96-102"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0