Neurosciences最新文献_第7页

The Effects of cervical mobilization and clinical pilates exercises in cervicogenic headache: randomized controlled trial. 颈椎活动和临床普拉提运动对颈源性头痛的影响：随机对照试验。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-10-01 DOI: 10.17712/nsj.2024.4.20240012

Meltem Uzun, Yasemin Ekmekyapar Fırat, Nevin Ergun, Türkan Akbayrak

{"title":"The Effects of cervical mobilization and clinical pilates exercises in cervicogenic headache: randomized controlled trial.","authors":"Meltem Uzun, Yasemin Ekmekyapar Fırat, Nevin Ergun, Türkan Akbayrak","doi":"10.17712/nsj.2024.4.20240012","DOIUrl":"10.17712/nsj.2024.4.20240012","url":null,"abstract":"Objectives: To investigate the effects of Cervical Mobilization (CM) and Clinical Pilates Exercises (CPE) in Cervigogenic Headache (CHA).Methods: The 37 patients were randomized into the 3 groups. The CM for 1st group, CPE for 2nd group and CM+CPE for 3rd group were applied 3 days/a week for 6 weeks. Pain frequency, pain intensity, number of analgesic, were recorded. The posture was measured by Posture Screen application, the cervical range of motion by the CROM device, deep neck flexor muscle endurance by the pressurized biofeedback device. Evaluations were applied 2 times as pre-post treatment.Results: In within-group comparison a decrease in pain parameters, neck-shoulder postural deviation and an increase DNFE and CROM were observed in all groups (p<0.05). In between-group comparison pain frequency, intensity and number of analgesics were significant changes in the CM and CM+CPE groups according to CPE (respectively p<0,001, p=0,001, p=0,018). Head and shoulder angulation were significant in the CPE and CM+CPE groups according to CM (respectively p=0.009, p=0,011). It was determined that the cervical right lateral flexion range of motion and right rotation were significant changes in the CM and CM+CPE groups according to CPE (respectively p=0,026, p=0,040). DNFE were significantly increased in CM+CPE according to CM and CPE (p=0.001).Conclusion: This study suggests that it would be beneficial to add CM and CPE to the treatment plans of patients with CHA.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 4","pages":"231-238"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical outcomes of optic neuritis: A retrospective study at a tertiary medical center in Saudi Arabia. 视神经炎的临床结果：沙特阿拉伯一家三级医疗中心的回顾性研究。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-10-01 DOI: 10.17712/nsj.2024.4.20230119

Yousra M Alturki, Hala T Jawa, Ghidaa A Alghamdi, Teyf M Althubiani, Mohammed T Bakhsh, Hassan M Alqurashi, Ahmed A Imam, Yaser M Elhams, Ahmed R Algethami, Omar M Babateen, Abdullah A Tawakul

{"title":"Clinical outcomes of optic neuritis: A retrospective study at a tertiary medical center in Saudi Arabia.","authors":"Yousra M Alturki, Hala T Jawa, Ghidaa A Alghamdi, Teyf M Althubiani, Mohammed T Bakhsh, Hassan M Alqurashi, Ahmed A Imam, Yaser M Elhams, Ahmed R Algethami, Omar M Babateen, Abdullah A Tawakul","doi":"10.17712/nsj.2024.4.20230119","DOIUrl":"10.17712/nsj.2024.4.20230119","url":null,"abstract":"Objectives: To investigate the clinical results of optic neuritis (ON) patients in a tertiary medical facility in Makkah, Kingdom of Saudi Arabia.Methods: The data of patients assessed for ON at Makkah, Saudi Arabia's King Abdullah Medical Center (KAMC), was examined retrospectively.Results: We identified 15 patients with ON. The ON was caused by multiple sclerosis (MS) in 73.3% of patients and neuromyelitis optica spectrum disorder (NMOSD) in 26.7% of patients. The disease was bilateral in 60% of patients and unilateral in 40% of patients. Additionally, 60% of patients had 2 or more episodes of ON, whereas 40% had a single episode. Patients with ON who presented with painful eye movements had a significantly longer disease duration (p=0.032). Moreover, patients whose disease duration was 11-15 days did not achieve a complete resolution of their symptoms and experienced some residual vision loss compared to 30.8% who had continued visual changes (p=0.049).Conclusion: In the studied population, multiple sclerosis was the most prevalent cause of ON. Women were more likely to have ON. The prognosis for eyesight was substantially connected with the length of ON.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 4","pages":"224-230"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on: Critically ill neuropathy alone is sufficient to explain proximal limb weakness and femoral nerve damage in severe SARS-CoV-2 infection. 评论仅重症神经病变就足以解释严重 SARS-CoV-2 感染者的近端肢体无力和股神经损伤。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-10-01 DOI: 10.17712/nsj.2024.4.20240071

Sinda Zarrouk, Josef Finsterer, Ameerah Alsaqobi

引用次数: 0

A rare case of pituitary dysfunction with Moyamoya disease. 一例罕见的垂体功能障碍并发 Moyamoya 病的病例。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-10-01 DOI: 10.17712/nsj.2024.4.20230118

Raseel A Aljthalin, Rawan A Albalawi, Ali H Alwadei, Atheer A Aljthalin

{"title":"A rare case of pituitary dysfunction with Moyamoya disease.","authors":"Raseel A Aljthalin, Rawan A Albalawi, Ali H Alwadei, Atheer A Aljthalin","doi":"10.17712/nsj.2024.4.20230118","DOIUrl":"10.17712/nsj.2024.4.20230118","url":null,"abstract":"Moyamoya disease is an idiopathic chronic and progressive vaso-occlusive disease ofthe bilateral intracranial branches of the internal carotid artery. Growth hormone failure, thyroid dysfunction, and low cortisol hormones are consequences of hypopituitarism. A 14-year-old girl with short stature presented with right-sided weakness associated with dysarthria. Ahormonal assay test showed abnormality ofthe anterior pituitary hormones. Magnetic resonance imaging of the brain and pituitary gland showed a reduction in the size of the adenohypophysis. A cerebral vessel angiogram showed multiple areas of stenosis in the right internal carotid artery. Magnetic resonance angiography demonstrated stenosis at the suprasellar region of the bilateral internal carotid artery. Pituitary dysfunction associated with moyamoya disease is rare but must be considered as adifferential diagnosis for any patient with hypopituitarism. Hypothalamopituitary dysfunction as result of carotid ischemia might be associated with moyamoya disease. Such patients require close follow-up and hormonal assay tests.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 4","pages":"288-291"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of clinician adherence to Fingolimod instructions and its effect on patient safety. 评估临床医生遵守芬戈莫德说明书的情况及其对患者安全的影响。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-07-01 DOI: 10.17712/nsj.2024.3.20240040

Alaa A Alhubaishi, Lolwa M Alsharekh, Haya F Almoharb, Faisal A Alqarni, Abdalhadi M Alqahtani, Mohammed K Alghazwni, Modhi A Alfuraydi, Abdulmajed Z Alsadi, Raad Y Altalhi, Tariq M Almutairi, Ghadah H Alshehri

{"title":"Assessment of clinician adherence to Fingolimod instructions and its effect on patient safety.","authors":"Alaa A Alhubaishi, Lolwa M Alsharekh, Haya F Almoharb, Faisal A Alqarni, Abdalhadi M Alqahtani, Mohammed K Alghazwni, Modhi A Alfuraydi, Abdulmajed Z Alsadi, Raad Y Altalhi, Tariq M Almutairi, Ghadah H Alshehri","doi":"10.17712/nsj.2024.3.20240040","DOIUrl":"10.17712/nsj.2024.3.20240040","url":null,"abstract":"Objectives: To assess clinicians' adherence to fingolimod's effective use according to the prescribed recommendations to reduce safety risk, identify the consequences, and highlight areas for improvement to policy makers for the benefit of both patient and care-giver.Methods: A retrospective observational study conducted at a tertiary hospital targeting multiple sclerosis patients on fingolimod from January 2017 to December 2021. The physicians' adherence to the manufacturer's instructions was assessed and categorized into good, moderate, and poor based on adherence to fingolimod instructions and monitoring measures. Four monitoring measures were assessed: bradycardia observation, ophthalmic examination, liver enzymes, and infections. In addition, the impact of adherence on patient safety was also assessed.Results: A total of 140 patients were included. Seventy-twopatients (51.4%) had physician with poor adherence (followed only one instruction or none). Sixty-five patients (46.4%) had 2-3 manufacture recommendations where physician's adherence was moderate. Three patients (2.10%) had all manufacturer's recommendations. In terms of fingolimod complications, 18 patients found to have bradycardia after the first does, macular oedema and infections was reported in 4 patients, and the elevation in hepatic enzymes was reported in 6 patients. Poor physician's adherence has resulted in treatment incompleteness and highest fingolimod discontinuation or switching to other treatment options.Conclusion: Adherence to fingolimod instructions was poor among physicians which resulted in highest drug switching or discontinuing rate.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"184-189"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leveraging multivariate analysis and adjusted mutual information to improve stroke prediction and interpretability. 利用多变量分析和调整后的互信息改进中风预测和可解释性。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-07-01 DOI: 10.17712/nsj.2024.3.20230100

Moutasem S Aboonq, Saeed A Alqahtani

{"title":"Leveraging multivariate analysis and adjusted mutual information to improve stroke prediction and interpretability.","authors":"Moutasem S Aboonq, Saeed A Alqahtani","doi":"10.17712/nsj.2024.3.20230100","DOIUrl":"10.17712/nsj.2024.3.20230100","url":null,"abstract":"Objectives: To develop a machine learning model to accurately predict stroke risk based on demographic and clinical data. It also sought to identify the most significant stroke risk factors and determine the optimal machine learning algorithm for stroke prediction.Methods: This cross-sectional study analyzed data on 438,693 adults from the 2021 Behavioral Risk Factor Surveillance System. Features encompassed demographics and clinical factors. Descriptive analysis profiled the dataset. Logistic regression quantified risk relationships. Adjusted mutual information evaluated feature importance. Multiple machine learning models were built and evaluated on metrics like accuracy, AUC ROC, and F1 score.Results: Key factors significantly associated with higher stroke odds included older age, diabetes, hypertension, high cholesterol, and history of myocardial infarction or angina. Random forest model achieved the best performance with accuracy of 72.46%, AUC ROC of 0.72, and F1 score of 0.74. Cross-validation confirmed its reliability. Top features were hypertension, myocardial infarction history, angina, age, diabetes status, and cholesterol.Conclusion: The random forest model robustly predicted stroke risk using demographic and clinical variables. Feature importance highlighted priorities like hypertension and diabetes for clinical monitoring and intervention. This could help enable data-driven stroke prevention strategies.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"190-196"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CAN PROBIOTICS PLUS VITAMIN D SUPPLEMENTS BENEFIT PEOPLE WITH SCHIZOPHRENIA? 益生菌加维生素 D 补充剂对精神分裂症患者有益吗？

IF 1.2 4区医学

Neurosciences Pub Date : 2024-07-01

引用次数: 0

Comment on: Effectiveness of radiology modalities in diagnosing and characterizing brain disorders. 评论：放射学模式在诊断和描述脑部疾病方面的有效性。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-07-01 DOI: 10.17712/nsj.2024.3.20240021

Sounira Mehri, Josef Finsterer, Saeed Bafaraj

引用次数: 0

WHO REPORTS WIDESPREAD OVERUSE OF ANTIBIOTICS IN PATIENTS HOSPITALIZED WITH COVID-19. 该研究报告指出，在患有 covid-19 的住院病人中普遍存在过度使用抗生素的现象。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-07-01

引用次数: 0

Optic disc characteristics on digital fundus photographs in Saudi children. 沙特儿童数字眼底照片上的视盘特征。

IF 1.2 4区医学

Neurosciences Pub Date : 2024-07-01 DOI: 10.17712/nsj.2024.3.20230124

Lina H Raffa, Esraa A Basalem

{"title":"Optic disc characteristics on digital fundus photographs in Saudi children.","authors":"Lina H Raffa, Esraa A Basalem","doi":"10.17712/nsj.2024.3.20230124","DOIUrl":"10.17712/nsj.2024.3.20230124","url":null,"abstract":"Objectives: To assess the optic disc parameters in healthy Saudi children.Methods: This study recruited 85 children who were medically free, born full-term, cooperative, and aged 3-17 years. The children underwent a thorough ophthalmological examination (visual acuity, refraction post-cycloplegia, fundus photography) at the ophthalmology clinic of King Abdulaziz University Hospital, Jeddah. Fundus photographs obtained by a fundus camera were evaluated by the Retinal Size Tool program.Results: Forty-eight participants were male (56.5%). The mean birth weight was 2.97±0.8 kg and the median gestational age was 39 weeks (range, 37-40 weeks). The median areas of the neuroretinal rim, cup, and optic disc were 1.82 mm2 (range, 0.84-2.83 mm2), 0.47 mm2 (range, 0.18-1.25 mm2), and 2.33 mm2 (range, 1.15-3.52 mm2), respectively. The older age group had smaller neuroretinal areas compared to the younger age groups. The variables demonstrated no apparent correlation to axial length, refraction, or birth parameters. The cup size increased together with the optic disc (r=0.659, p<0.001). Sex and refraction did not correlate with any of the studied factors.Conclusion: This study yielded normative data for the optic disc parameters of healthy Saudi children. The data can be used as a reference in the pediatric ophthalmology clinic to aid the identification of optic disc abnormalities.","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"161-167"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0