{"title":"CAN PROBIOTICS PLUS VITAMIN D SUPPLEMENTS BENEFIT PEOPLE WITH SCHIZOPHRENIA?","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"210"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurosciencesPub Date : 2024-07-01DOI: 10.17712/nsj.2024.3.20240021
Sounira Mehri, Josef Finsterer, Saeed Bafaraj
{"title":"Comment on: Effectiveness of radiology modalities in diagnosing and characterizing brain disorders.","authors":"Sounira Mehri, Josef Finsterer, Saeed Bafaraj","doi":"10.17712/nsj.2024.3.20240021","DOIUrl":"10.17712/nsj.2024.3.20240021","url":null,"abstract":"","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"207-209"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"WHO REPORTS WIDESPREAD OVERUSE OF ANTIBIOTICS IN PATIENTS HOSPITALIZED WITH COVID-19.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"213-214"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurosciencesPub Date : 2024-07-01DOI: 10.17712/nsj.2024.3.20230124
Lina H Raffa, Esraa A Basalem
{"title":"Optic disc characteristics on digital fundus photographs in Saudi children.","authors":"Lina H Raffa, Esraa A Basalem","doi":"10.17712/nsj.2024.3.20230124","DOIUrl":"10.17712/nsj.2024.3.20230124","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the optic disc parameters in healthy Saudi children.</p><p><strong>Methods: </strong>This study recruited 85 children who were medically free, born full-term, cooperative, and aged 3-17 years. The children underwent a thorough ophthalmological examination (visual acuity, refraction post-cycloplegia, fundus photography) at the ophthalmology clinic of King Abdulaziz University Hospital, Jeddah. Fundus photographs obtained by a fundus camera were evaluated by the Retinal Size Tool program.</p><p><strong>Results: </strong>Forty-eight participants were male (56.5%). The mean birth weight was 2.97±0.8 kg and the median gestational age was 39 weeks (range, 37-40 weeks). The median areas of the neuroretinal rim, cup, and optic disc were 1.82 mm<sup>2</sup> (range, 0.84-2.83 mm<sup>2</sup>), 0.47 mm<sup>2</sup> (range, 0.18-1.25 mm<sup>2</sup>), and 2.33 mm<sup>2</sup> (range, 1.15-3.52 mm<sup>2</sup>), respectively. The older age group had smaller neuroretinal areas compared to the younger age groups. The variables demonstrated no apparent correlation to axial length, refraction, or birth parameters. The cup size increased together with the optic disc (r=0.659, <i>p</i><0.001). Sex and refraction did not correlate with any of the studied factors.</p><p><strong>Conclusion: </strong>This study yielded normative data for the optic disc parameters of healthy Saudi children. The data can be used as a reference in the pediatric ophthalmology clinic to aid the identification of optic disc abnormalities.</p>","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"161-167"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurosciencesPub Date : 2024-07-01DOI: 10.17712/nsj.2024.3.20230111
Yaser M Al Malik
{"title":"Tumefactive demyelinating lesions: A literature review of recent findings.","authors":"Yaser M Al Malik","doi":"10.17712/nsj.2024.3.20230111","DOIUrl":"10.17712/nsj.2024.3.20230111","url":null,"abstract":"<p><p>Tumefactive demyelinating lesion is a variant of multiple sclerosis that is a diagnostic challenge. Tumefactive demyelinating lesion requires extensive work-up as its clinical and radiological features are often indistinguishable from other central nervous system lesions, such as tumors. Diagnosis is further complicated by the increasing recognition that tumefactive demyelinating lesions can occur alongside, evolve into, or develop from numerous conditions other than multiple sclerosis, pointing to a possible overlapping etiology. We review herein relevant studies from 2017 onwards to provide a current view on the pathogenesis, clinical and imaging findings, novel diagnostic techniques for differential diagnoses, and management of tumefactive demyelinating lesions.</p>","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"153-160"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intracerebral benign fibrous histiocytoma.","authors":"Liusong Yang, Mingzhe Zheng, Yingfeng Zhu, Zhongqing Chen","doi":"10.17712/nsj.2024.3.202300116","DOIUrl":"10.17712/nsj.2024.3.202300116","url":null,"abstract":"<p><p>Benign fibrous histiocytoma (BFH) within the intracerebral region is remarkably rare. Our report details 2 cases of unusual BFH instances that exhibit no adhesion to the dura mater or cerebral falx, accompanied by a comprehensive literature review. While magnetic resonance imaging demonstrates specific characteristics for BFH, it does not readily differentiate BFH from more common brain neoplasms like gliomas and metastatic tumors. The definitive diagnosis of BFH depends primarily on histopathological and immunohistochemical examinations. Total surgical resection is considered an efficacious therapeutic approach, emphasizing the necessity for prolonged postoperative surveillance to detect any potential tumor recurrence or metastasis.</p>","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"201-206"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Can artificial intelligence techniques help clinicians assess and treat patients with bone fractures?","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"211"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurosciencesPub Date : 2024-07-01DOI: 10.17712/nsj.2024.3.20230003
Shanshan Chen, Hongrong Cheng, Guohua Zhao
{"title":"The genetic spectrum of <i>NF1</i> variants in 10 unrelated Chinese families with neurofibromatosis type 1.","authors":"Shanshan Chen, Hongrong Cheng, Guohua Zhao","doi":"10.17712/nsj.2024.3.20230003","DOIUrl":"10.17712/nsj.2024.3.20230003","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the clinical and genetic features in a cohort of Chinese families with neurofibromatosis type 1 (NF1).</p><p><strong>Methods: </strong>The clinical information of 21 patients with <i>NF1</i> in 10 families was retrospectively analyzed. To broaden the genetic spectrum of <i>NF1</i>, multiplex ligation-dependent probe amplification analysis was performed first, followed by the whole-exome sequencing, in order to identify pathogenic or potentially pathogenic variants of <i>NF1</i> gene in 10 unrelated Chinese families.</p><p><strong>Results: </strong>Nine different <i>NF1</i> variants were identified in all 10 families. Of these, 7 were known pathogenic variants and included the exon 1 deletion, exons 1-58 deletion, c.5401C>T (p.Q1801*), c.2291-2A>C, c.484C>T (p.Q162*), c.4922G>A (p.W1641*) and c.1019_1020del (p.S340Cfs*25). The 2 novel variants were c.5197T>C (p.S1733P) and c.783_797delinsC (p.K261Nfs*25). The p.S1733P variant was classified as a variant of uncertain significance, while p.K261Nfs*25 was classified as pathogenic. Hence, the positive detection rate of <i>NF1</i> variants was 100% (10/10). While the truncating variants were responsible for 60.0% (6/10) of the cases, the splicing variant was responsible for 10% (1/10) of the cases.</p><p><strong>Conclusion: </strong>We identified 2 novel heterozygous variants (c.5197T>C and c.783_797delinsC) in the <i>NF1</i> gene, which broadens the genetic spectrum of the <i>NF1</i> gene.</p>","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"177-183"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurosciencesPub Date : 2024-07-01DOI: 10.17712/nsj.2024.3.20230086
Walaa A Aldarwish, Rakan F Alshammari, Bader A AlEnzi
{"title":"Traumatic vertebral artery dissection associated with cervical neck traction devices.","authors":"Walaa A Aldarwish, Rakan F Alshammari, Bader A AlEnzi","doi":"10.17712/nsj.2024.3.20230086","DOIUrl":"10.17712/nsj.2024.3.20230086","url":null,"abstract":"<p><p>Cervical arterial dissection (CAD) is a common cause of stroke in young people which can be classified as either spontaneous or traumatic. The primary initial symptoms are headache, neck pain, and dizziness. Recently, a 57-year-old woman experienced a severe headache after using a cervical neck traction device. Radiological examination of the head and neck revealed right vertebral artery dissection, which emphasizes the importance of recognizing that using cervical neck traction devices increases the risk of traumatic vertebral artery dissection.</p>","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"197-200"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"STRENGTHENED GLOBAL CAPACITIES ON CLIMATE CHANGE AND HEALTH: WHO TRAINING IN MADRID.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"29 3","pages":"212-213"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}