NeurosciencesPub Date : 2025-04-01DOI: 10.17712/nsj.2025.30.4.20240037
Kaya S Sancar, Çelik Şeref, Göksu Hamit, Akçaboy E Yavuz, Şahin Şaziye
{"title":"Does the severity of facet joint osteoarthritis affect facet medial branch radiofrequency thermocoagulation results?","authors":"Kaya S Sancar, Çelik Şeref, Göksu Hamit, Akçaboy E Yavuz, Şahin Şaziye","doi":"10.17712/nsj.2025.30.4.20240037","DOIUrl":"10.17712/nsj.2025.30.4.20240037","url":null,"abstract":"<p><strong>Objectives: </strong>To assess how facet medial branch radiofrequency thermocoagulation (FMB-RFT) outcomes are affected by severe facet joint osteoarthritis (FJO).</p><p><strong>Methods: </strong>This retrospective study involved 91 individuals with lumbar facet joint disease-related chronic lower back pain (CLBP), all of whom underwent FMB-RFT. The patients were assigned to 3 groups using the Weishaupt facet grading system (WFGS). Pain scores were assessed prior to treatment, as well as at the 1-, 6-, and 12-month marks.</p><p><strong>Results: </strong>Based on the WFGS, 38 of the 91 patients were assigned a grade 1 FJO, 28 a grade 2 FJO, and 25 a grade 3 FJO. The percentage of patients in each group who saw a 50% or greater improvement in their pain scores at 1, 6, and 12 months did not differ significantly.</p><p><strong>Conclusion: </strong>For patients with CLBP, FMB-RFT has been shown to be safe and effective in both the short and long terms. The results from FMB-RFT do not seem to be affected by the severity of FJO.</p>","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"30 2","pages":"144-149"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurosciencesPub Date : 2025-04-01DOI: 10.17712/nsj.2025.2.20240127
{"title":"Comment on: Sleep patterns and quality depend not only on gender and the time of year, but also on a variety of other influencing factors.","authors":"","doi":"10.17712/nsj.2025.2.20240127","DOIUrl":"10.17712/nsj.2025.2.20240127","url":null,"abstract":"","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"30 2","pages":"162-163"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurosciencesPub Date : 2025-04-01DOI: 10.17712/nsj.2025.2.20240097
Faisal A Al-Suwaidan, Hajer Y Almudaiheem, Haifa F Alotaibi, Waleed A Alhazzani, Khalid W Al-Quliti, Khalidah A Alenzi, Bedor A Al-Omari, Majed M Alabdali, Abubker W Omaer, Saleh M Alrajhi, Ali N Alshoaiby, Ahmed H Al-Jedai
{"title":"Saudi clinical practice guidelines for the treatment and prevention of migraine headache.","authors":"Faisal A Al-Suwaidan, Hajer Y Almudaiheem, Haifa F Alotaibi, Waleed A Alhazzani, Khalid W Al-Quliti, Khalidah A Alenzi, Bedor A Al-Omari, Majed M Alabdali, Abubker W Omaer, Saleh M Alrajhi, Ali N Alshoaiby, Ahmed H Al-Jedai","doi":"10.17712/nsj.2025.2.20240097","DOIUrl":"10.17712/nsj.2025.2.20240097","url":null,"abstract":"<p><strong>Objective: </strong>To develop clinical practice guidelines based on evidence based medicine on the use of abortive and preventive therapies for managing migraine headaches. We formulated these guidelines to offer evidence-based recommendations to improve the knowledge of physicians, healthcare professionals, and policymakers in migraine headache management.</p><p><strong>Method: </strong>A panel of 11 experts from different sectors in Saudi Arabia approved 26 questions on abortive and preventive therapies for migraines. To develop each question, we searched \"PubMed\" and \"Cochrane Library\" databases for recent relevant systematic reviews published between 2013 and 2024. We employed the Grading Recommendations, Assessment, Development, and Evaluation methodological approach to ensure the certainty of the collated evidence and to formulate the recommendations. The expert panel voted electronically on each recommendation, and a consensus was defined as >70% agreement.</p><p><strong>Results: </strong>We formulated a total of 26 recommendations. Of these, 14 are focused on abortive therapy for acute migraine attacks, whereas 12 are focused on the prevention of episodic or chronic migraines. These guidelines strongly recommend the use of paracetamol and ibuprofen as the first-line treatment for mild to moderate migraine. Furthermore, we concluded that propranolol should be considered as the first-line preventive intervention for migraine.</p><p><strong>Conclusion: </strong>The Saudi clinical practice guidelines offer systematically validated recommendations of migraine headaches in adults. The recommendations are potentially beneficial for all healthcare professionals managing patients with migraine headaches.</p>","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"30 2","pages":"77-91"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurosciencesPub Date : 2025-04-01DOI: 10.17712/nsj.2025.2.20240089
Shaden S Alfayez, Muddathir H Hamad, Amal Y Kentab, Ahmad A Alanezi, Daniah M Kurdi, Hanady A Almuhideb, Fahad A Bashiri
{"title":"Risk factors, clinical characteristics, and outcomes of perinatal stroke in a Tertiary University Hospital.","authors":"Shaden S Alfayez, Muddathir H Hamad, Amal Y Kentab, Ahmad A Alanezi, Daniah M Kurdi, Hanady A Almuhideb, Fahad A Bashiri","doi":"10.17712/nsj.2025.2.20240089","DOIUrl":"10.17712/nsj.2025.2.20240089","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the risk factors, clinical characteristics, and neurodevelopmental outcomes associated with perinatal stroke, as well as to assess the risk of epilepsy, seizure control, and cognitive function in children with perinatal stroke.</p><p><strong>Methods: </strong>Data from 32 patients diagnosed with perinatal stroke between October 2007 and October 2020 were retrospectively reviewed.</p><p><strong>Results: </strong>Of 32 patients, 27 were born after normal pregnancies, and 20 (62.5%) had consanguineous parents. Family histories of stroke, haematological disease, and epilepsy were noted in 3.13%, 3.13%, and 21.88%, respectively. Initial symptoms included hemiparesis (56.25%), seizures (37.5%), respiratory distress (3.13%), and tiptoe walking (3.13%). Epilepsy was diagnosed in 22 patients, with 72.72% achieving seizure control. Among 12 patients who underwent IQ testing, 15.63% had borderline impairment, 9.37% average IQ, 3.13% below-average IQ, and 6.26% moderate-to-severe impairment.</p><p><strong>Conclusion: </strong>Hemiparesis was the most frequent presenting symptom, followed by seizures. Many patients developed epilepsy, with most achieving satisfactory seizure control. IQ testing revealed varying degrees of cognitive impairment, highlighting the complex neurodevelopmental effects of perinatal stroke.</p>","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"30 2","pages":"138-143"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"WHO PREQUALIFIES DIAGNOSTIC TEST TO SUPPORT SAFER ADMINISTRATION OF P. VIVAX MALARIA TREATMENTS.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"30 2","pages":"167-168"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DOES SLEEP APNEA TREATMENT INFLUENCE PATIENTS' RISK OF GETTING INTO CAR ACCIDENTS?","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"30 2","pages":"166"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurosciencesPub Date : 2025-04-01DOI: 10.17712/nsj.2025.2.20240101
Abdulmohsen H Al-Zalabani
{"title":"The association between cigarette smoking and sleep deprivation among adolescents in Gulf Cooperation Council countries: analysis of national surveys.","authors":"Abdulmohsen H Al-Zalabani","doi":"10.17712/nsj.2025.2.20240101","DOIUrl":"10.17712/nsj.2025.2.20240101","url":null,"abstract":"<p><strong>Objectives: </strong>To examine the association between sleep deprivation and cigarette smoking among adolescents in the \"Gulf Cooperation Council (GCC)\" countries, accounting for relevant sociodemographic and behavioral factors.</p><p><strong>Methods: </strong>The present study was conducted between June and August 2024 using data from the most recent \"Global School-based Student Health Survey (GSHS)\" conducted in 5 GCC countries. The study included 21,105 adolescents aged 11-18 years. Multiple logistic regression models were used to examine the association in each country. A random-effects meta-analysis was conducted to synthesize results across countries.</p><p><strong>Results: </strong>Overall, 17.9% of adolescents reported sleep deprivation. The pooled adjusted odds ratio for the association between cigarette smoking and sleep deprivation was 1.75 (95% CI: 1.56-1.96), indicating that adolescents who smoked cigarettes had 75% higher odds of experiencing sleep deprivation compared to non-smokers. This association was consistent across all 5 GCC countries, with low heterogeneity (I² = 18.1%).</p><p><strong>Conclusion: </strong>This study provides evidence of a significant positive association between sleep deprivation and cigarette smoking among adolescents in GCC countries. These findings emphasize the need for comprehensive public health interventions promoting both smoking prevention and sleep health among adolescents in the region.</p>","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"30 2","pages":"117-123"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MILESTONE: COVID-19 FIVE YEARS AGO.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"30 2","pages":"167"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"STUDY REVEALS LINKS BETWEEN MANY PESTICIDES AND PROSTATE CANCER.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"30 2","pages":"165"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977578/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurosciencesPub Date : 2025-04-01DOI: 10.17712/nsj.2025.2.20240094
Yaser M Al Malik, Awad S Alharbi, Mohammed A Alfurayh, Abdulaziz A Aldalaan, Abdulazeez M Alzailaie, Eid D Alanazi, Ahmad A Abulaban, Seraj O Makkawi, Asma A Alanazi
{"title":"Do people with multiple sclerosis in Saudi Arabia want to know their prognosis? A cross-sectional nationwide study.","authors":"Yaser M Al Malik, Awad S Alharbi, Mohammed A Alfurayh, Abdulaziz A Aldalaan, Abdulazeez M Alzailaie, Eid D Alanazi, Ahmad A Abulaban, Seraj O Makkawi, Asma A Alanazi","doi":"10.17712/nsj.2025.2.20240094","DOIUrl":"10.17712/nsj.2025.2.20240094","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate whether Persons with MS (pwMS) in Saudi Arabia want to discuss their long-term prognosis (LTP) and the factors influencing this decision using a self-administered online questionnaire.</p><p><strong>Methods: </strong>In this cross-sectional study, an online questionnaire was distributed from December 2022 to July 2023 across Saudi Arabia to determine pwMS interest in discussing their LTP. Participants included patients over 18 years, of any gender, diagnosed with MS. A nonprobability convenience sampling technique was used, with questionnaires sent through MS organizations and channels.</p><p><strong>Results: </strong>Almost two-thirds (66-68%) of the 375 respondents reported that their LTP had never been discussed during neurologist appointments and expressed uncertainty about it. Additionally, 23.5% noted discrepancies in information provided by different neurologists. Most (81.6%) expressed a desire for a prognostic tool at diagnosis. In this study, MS patients' desire to learn about a tool for assessing long-term prognosis was significantly associated with age, education level (<i>p</i><0.001), and gender (<i>p</i>=0.02). A higher percentage of women (65.7%) showed interest in learning about the tool compared to men (34.3%).</p><p><strong>Conclusion: </strong>While more than half of pwMS are curious about their prognosis, only about one-third have optimal discussions about LTP with neurologists. Many desire information on prognostic tools. Further research is needed to assess patients' knowledge of their prognosis and improve communication with physicians.</p>","PeriodicalId":19284,"journal":{"name":"Neurosciences","volume":"30 2","pages":"108-116"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}