Nicotine & Tobacco Research最新文献

{"title":"Advancing Science, Improving Health, and Saving Lives in an Evolving Research Landscape.","authors":"Mariel S Bello, Brandon Henderson, Megan Passey, Bruce Wheeler, Eric C Donny, Christie D Fowler","doi":"10.1093/ntr/ntaf093","DOIUrl":"https://doi.org/10.1093/ntr/ntaf093","url":null,"abstract":"","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144033989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Note on Ordinal Modeling of Smoking Rate Data.","authors":"Donald Hedeker, Robin J Mermelstein, Juned Siddique","doi":"10.1093/ntr/ntaf087","DOIUrl":"https://doi.org/10.1093/ntr/ntaf087","url":null,"abstract":"<p><strong>Introduction: </strong>This paper discusses statistical models for ordinal data that may be more appropriate for smoking rate outcomes than are models that assume continuous measurement and normality. Smoking rate outcomes often have distributions that make them inappropriate for many popular statistical models that assume normality, and are more appropriately considered ordinal outcomes. This article describes how the ordinal logistic regression model can be used to obtain estimates of means, and comparisons of means, for smoking rate outcomes.</p><p><strong>Methods: </strong>Analyses of the daily smoking rate of a sample of 383 subjects are presented using linear regression and ordinal logistic regression. From the latter, we derive regression estimates (intercepts and slopes) in terms of the mean response without having to assume any distributional form for the smoking rate outcome variable. Regressors considered are the subject's gender and their level of dependency as assessed by the nicotine dependence symptom scale (NDSS).</p><p><strong>Results: </strong>Estimated regression coefficients were similar, but the linear regression model indicated a significant gender effect, such that females had a higher smoking rate than males. Though similar, this effect was not quite significant (at the 0.05 level) in the ordinal model. The effect of dependency was significant in both models, with more dependent smokers having a higher smoking rate.</p><p><strong>Conclusions: </strong>Results and conclusions can depend on the assumptions of a statistical model. Methods relaxing the assumption of normality are useful to examine how robust effects are to this common assumption.</p><p><strong>Implications: </strong>Modeling of smoking rate outcomes can be performed without having to rely on methods that assume a normal distribution. The ordinal model can provide estimates relating to mean differences in smoking rate for the effects of regressors.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Low-Dose Computed Tomography Findings on Cigarette Smoking Cessation Among High-Risk Adults Participating in Lung Cancer Screening.","authors":"Evangelos Katsampouris, Amyn Bhamani, Fanta Bojang, Jennifer L Dickson, Helen Hall, Carolyn Horst, Priyam Verghese, Andrew Creamer, Ruth Prendecki, Chuen Khaw, Sophie Tisi, John McCabe, Kylie Gyertson, Anne-Marie Hacker, Laura Farrelly, Neal Navani, Allan Hackshaw, Sam M Janes, Samantha L Quaife","doi":"10.1093/ntr/ntaf010","DOIUrl":"https://doi.org/10.1093/ntr/ntaf010","url":null,"abstract":"<p><strong>Introduction: </strong>Integrating effective smoking cessation strategies for individuals undergoing lung cancer screening stands to significantly increase the impact of lung screening programmes. We assessed the impact of low-dose computed tomography (LDCT) findings on smoking cessation among high-risk adults who currently smoked.</p><p><strong>Aims and methods: </strong>13 035 individuals, aged 55-77 years, attended a lung health check appointment, as part of a prospective observational cohort study (the SUMMIT Study), prior to undergoing a baseline LDCT scan. Logistic regressions examined the likelihood of smoking cessation at a 1-year follow-up appointment and its association with LDCT findings.</p><p><strong>Results: </strong>12.6% (n = 647/5135) of individuals self-reported smoking cessation at 1-year follow-up. Higher odds of quitting were found in those receiving indeterminate pulmonary nodule findings requiring a 3-month interval LDCT (aOR = 1.27; 1.01, 1.61), those with urgent findings requiring referral to secondary care (aOR = 1.55; 1.05, 2.32), and those with a possible new chronic obstructive pulmonary disease diagnosis (aOR = 1.60; 1.23, 2.06), compared to those receiving no actionable LDCT findings. Older age, Asian ethnic background, current high smoking intensity, motivation and number of quit attempts, and low nicotine dependence were associated with increased odds of quitting.</p><p><strong>Conclusions: </strong>Individuals currently smoking, at high lung cancer risk, participating in LDCT screening, and receiving incidental findings requiring a 1-year interval LDCT or primary care follow-up might therefore need additional behavioral support to quit. Tailored communication strategies depending on the severity of the LDCT findings, including additional behavioral support for those with less clinical concerning or negative findings, could increase quit rates and reduce smoking-related morbidity.</p><p><strong>Implications: </strong>This study reports high odds of self-reported complete smoking cessation in adults who currently smoked after receiving their LDCT findings. Though the impact of specific types of LDCT findings on smoking cessation was positive for high lung cancer risk individuals, reception of incidental findings could potentially be perceived as less severe to encourage individuals who currently smoked to quit. Clearly communicating the severity of LDCT findings along with the delivery of behavioral smoking cessation support targeted to high-risk individuals may increase their chances of complete smoking cessation and reduce lung cancer mortality.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Letter to the Editor: Stepwise rather than linear trend in prevalence of secondhand tobacco exposure among children.","authors":"Yudai Tamada, Kenji Takeuchi, Takahiro Tabuchi","doi":"10.1093/ntr/ntaf090","DOIUrl":"https://doi.org/10.1093/ntr/ntaf090","url":null,"abstract":"","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in Electronic Nicotine Delivery Systems and Cigarette Use Among Texas College Students, 2015-2024.","authors":"Caroline North, Hien Nguyen, Xiaoyin Li, Alexandra Loukas","doi":"10.1093/ntr/ntaf086","DOIUrl":"https://doi.org/10.1093/ntr/ntaf086","url":null,"abstract":"<p><strong>Introduction: </strong>We examined trends in past 30-day electronic nicotine delivery systems (ENDS) and past 30-day cigarette use among Texas college students from 2015-2024. We hypothesized that ENDS use would a) decline from 2015-2017 similar to national surveillance research, b) increase from 2017-2019 after the surging popularity of JUUL and similar pod-vapes, and then c) decline again from 2019-2024 after the enactment of federal tobacco policies and the onset of the COVID-19 pandemic. We also hypothesized that cigarette smoking would decline steadily over the ten-year period.</p><p><strong>Methods: </strong>Participants were 45,129 18-25-year-old Texas college students who participated in at least one of ten repeated cross-sectional surveys from 2015-2024. Discontinuous growth curve models were used to analyze trends in past 30-day ENDS use and cigarette smoking across the 10-year period.</p><p><strong>Results: </strong>Results indicated that ENDS use decreased from 2015-2017 (AOR=0.88, 95%CI: 0.81, 0.96), increased from 2017-2019 (AOR=2.08, 95%CI: 1.96, 2.20), and then decreased from 2019-2024 (AOR=0.95, 95%CI: 0.93, 0.97). Past 30-day cigarette smoking decreased steadily across the ten-year study period (AOR = 0.82, 95%CI: 0.80, 0.83).</p><p><strong>Conclusions: </strong>Findings suggest that while cigarette use has declined over the past decade among Texas college students, there have been inconsistent changes in ENDS use. Although the present study cannot infer causaility, these changes align with the timing of tobacco legislation and FDA regulations. The sharp increase in ENDS between 2017-2019 highlights the need to remain vigilant about new products and marketing strategies from tobacco companies, as they may undermine the effectiveness of tobacco control efforts.</p><p><strong>Implications: </strong>The present study provides new information on trends in cigarette and ENDS use among college students in Texas, a state with minimal tobacco control efforts. While cigarette use has steadily decreased over the past decade, ENDS use has fluctuated, and remains high. Policy efforts made at the national level may aid in tobacco prevention and cessation efforts in states with minimal tobacco control efforts.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Stop-Smoking Strategy After Cervical Cancer Screening: Results of a Cluster-Randomized Controlled Trial in Dutch General Practice.","authors":"Marthe B L Mansour, Mathilde R Crone, Henk C van Weert, Niels H Chavannes, Kristel M van Asselt","doi":"10.1093/ntr/ntae285","DOIUrl":"10.1093/ntr/ntae285","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to assess whether brief stop-smoking advice given to women who smoke and visit their general practice for cervical cancer screening improves smoking cessation outcomes.</p><p><strong>Aims and methods: </strong>This two-arm cluster-randomized controlled trial was conducted in 75 Dutch general practices. Participants in the intervention group received brief stop-smoking advice based on the Ask-Advise-Connect method, delivered by a practice assistant. Patient-reported outcomes were measured at 6 months: undertaking a serious quit attempt of at least 24 hours during follow-up (primary outcome), 7-day point prevalence abstinence at 6 months, reduction in number of cigarettes smoked, increase in motivation to quit smoking, exposure to advice or support, and other psychological and behavioral measurements.</p><p><strong>Results: </strong>There was no significant difference in undertaking a serious quit attempt between the intervention (39.8% of n = 266) and control group (36.0% of n = 214), odds ratio 1.18 (95% confidence intervals: 0.80-1.72, p = .41). Neither did the point prevalence abstinence significantly differ between groups: 21.1% versus 16.3%, odds ratio 1.38 (95% confidence interval: 0.83-2.29, p = .21). Although nonsignificant, the direction of effects for the aforementioned outcomes was in favor of the intervention group. The reduction in the number of cigarettes smoked and increase in motivation to quit did not differ between groups. The uptake of cessation counseling was higher in the intervention (14.7%) than in the control group (2.8%).</p><p><strong>Conclusions: </strong>A brief stop-smoking strategy after the smear test for cervical screening might encourage women who smoke to attempt quitting and seek cessation counseling, but a significant effect could not be demonstrated in this trial.</p><p><strong>Implications: </strong>The results of this cluster-randomized trial suggest that brief advice to stop-smoking delivered by a practice assistant after routine cervical screening in general practice might encourage women who smoke to attempt quitting, but a significant effect could not be proven. Also, women who receive advice show a higher uptake of professional cessation counseling compared to their controls. Providing brief advice after the cervical smear might therefore be a useful opportunistic approach to stimulate cessation in women who smoke.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":"805-814"},"PeriodicalIF":3.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Nicotine Pharmacokinetics of New-Generation Tobacco Products and Conventional Cigarettes: A Systematic Review and Meta-analysis.","authors":"Yue Cao, Xinru Liu, Zhongyi Hu, Jiaxuan Li, Xi Chen, Yuming Xiong, Fangzhen Zheng, Jianqiang Zhang, Lin Zhang, Xiaona Liu","doi":"10.1093/ntr/ntae199","DOIUrl":"10.1093/ntr/ntae199","url":null,"abstract":"<p><strong>Introduction: </strong>New-generation tobacco products (NGPs) hold promises as modified-risk alternatives to conventional cigarettes (CCs), given their comparable characteristics. This study investigated the nicotine pharmacokinetics (PK) of NGPs, encompassing closed pod systems, refillable e-cigarettes (ECs), and heated tobacco products (HTPs), in comparison to CCs through systematic review and meta-analysis.</p><p><strong>Aims and methods: </strong>A comprehensive search was conducted on PubMed, Embase, and Web of Science for articles published between January 2013 and July 2023. Maximum nicotine concentration (Cmax), time to peak concentration (Tmax), and total nicotine exposure (area under the concentration-time curve, AUC) were extracted to evaluate nicotine delivery PK. Random effects meta-analyses were performed to determine pooled standardized mean differences, facilitating a comparison of PK profiles between NGPs and CCs. Subgroup analyses exploring flavors and nicotine concentrations across NGPs, and CCs were also conducted.</p><p><strong>Results: </strong>The meta-analysis incorporated 30 articles with 2728 participants. Cmax and AUC were significantly lower for NGPs, while Tmax demonstrated statistical similarity compared to CCs. Among three NGPs, Cmax, and AUC were lower for closed pod systems and refillable ECs. In HTPs, Cmax was statistically similar while AUC was lower compared to CCs. Tmax was statistically similar in closed pod systems and HTPs compared to that of CCs. No significant difference was observed in the comparisons of PK between each type of NGPs versus CCs.</p><p><strong>Conclusions: </strong>NGPs delivered less nicotine than CCs but reached Cmax over a similar timeframe, indicating that NGPs may serve as modified-risk alternatives with lower nicotine delivery to CCs for craving relief and smoking cessation.</p><p><strong>Implications: </strong>This study suggested that NGPs, such as the closed pod systems, the refillable ECs, and the HTPs, delivered either lower or comparable nicotine levels and achieved peak nicotine concentration at a similar rate as CCs. Our findings carry implications that NGPs can serve as modified-risk nicotine alternatives to CCs in helping smokers manage cravings and potentially quit smoking, thereby highlighting their value in the field of tobacco harm reduction.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":"783-793"},"PeriodicalIF":3.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142004826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clarification on the National Institute of Public Health's Independence from the Tobacco Industry.","authors":"Tomofumi Sone","doi":"10.1093/ntr/ntae265","DOIUrl":"10.1093/ntr/ntae265","url":null,"abstract":"","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":"942"},"PeriodicalIF":3.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142624976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Generating Campaign Awareness With Digital Media: Exploring Factors Associated With Awareness of and Receptivity to FDA's Fresh Empire Tobacco Prevention Campaign.","authors":"Amy Henes, Laurel Curry, Matthew Farrelly, Jamie Guillory, Andrew Crichton, McKinley Saunders, Anna MacMonegle, Debra Mekos, Xiaoquan Zhao, James Nonnemaker, Merrybelle Guo, Dana E Wagner","doi":"10.1093/ntr/ntae269","DOIUrl":"10.1093/ntr/ntae269","url":null,"abstract":"<p><strong>Introduction: </strong>We explore factors that were associated with awareness of and receptivity to U.S. Food and Drug Administration's Fresh Empire tobacco public education campaign.</p><p><strong>Aims and methods: </strong>Evaluation data were 10 674 survey responses from 5129 unique respondents who identified with the Hip Hop peer crowd between 2016 and 2019. The sample was predominantly non-Hispanic Black and Hispanic youth. We assessed the outcomes of brand awareness, ad awareness, and perceived ad effectiveness. We used panel regression models to test which demographic and other characteristics-including potential campaign exposure, as measured by impressions assigned to respondents based on their media market of residence and survey completion date-were associated with these outcomes.</p><p><strong>Results: </strong>Black, non-Hispanic youth; Hispanic youth; and youth with additional non-Hispanic or multiracial identities were more likely to be aware of the Fresh Empire brand and reported higher ad awareness and perceived effectiveness scores than White, non-Hispanic respondents. Among the full sample, respondents with higher Hip Hop scores-indicating greater identification with the Hip Hop peer crowd-reported higher ad awareness. Compared with nonsusceptible never smokers, youth susceptible to smoking reported lower ad awareness and perceived effectiveness scores. Higher potential exposure to campaign broadcast and digital media were both associated with higher ad awareness.</p><p><strong>Conclusions: </strong>Fresh Empire reached and appealed to a racially and ethnically diverse group of Hip Hop youth. Our findings highlight the ability of digital media to generate campaign awareness among specific youth audiences.</p><p><strong>Implications: </strong>Understanding factors that contribute to awareness of and positive reactions to the Fresh Empire campaign can inform the development and implementation of future campaigns focused on Hip Hop youth, youth of color, and other underrepresented audiences. Fresh Empire's success in reaching its audience using primarily digital media demonstrates the potential of digital media campaigns to be effective at reaching specific audiences with tobacco prevention messages.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":"864-872"},"PeriodicalIF":3.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"E-Cigarette Brand Use by Race/Ethnicity in a US Sample of Adolescent and Young Adult E-Cigarette Users, 2022-2023.","authors":"Jennifer M Kreslake, Adrian Bertrand, Tyler Minter, Barbara A Schillo","doi":"10.1093/ntr/ntae174","DOIUrl":"10.1093/ntr/ntae174","url":null,"abstract":"<p><strong>Introduction: </strong>To determine whether e-cigarette brand use varies according to race/ethnicity among adolescent and young adult e-cigarette users.</p><p><strong>Aims and methods: </strong>Data are from a cross-sectional online survey of respondents aged 15-24 years (January 2022-June 2023; 300 unique respondents/week). The analytic sample was restricted to current e-cigarette users (n = 6387). Respondents selected their usual brand and reported frequency of past 30-day e-cigarette use (in days). ANOVAs measured differences in frequency of use by usual brand, stratified by race/ethnicity. Linear regression identified changes in usual brand over time by race/ethnicity, controlling for age and use of other tobacco/nicotine products.</p><p><strong>Results: </strong>One-quarter (25.6%) of Black and 22.2% of Hispanic e-cigarette users reported JUUL as their usual brand, compared to those who are White (15.7%) or another race (16.5%). Puff Bar was the second-most reported brand among Black (15.1%) or Hispanic (16.6%) e-cigarette users, to a greater extent than White (7.8%) e-cigarette users. Frequency of use varied significantly according to respondents' usual brand when stratified by race/ethnicity (p < .001).</p><p><strong>Conclusions: </strong>Across all racial and ethnic categories, frequency of use was greater for brands marketed with more flavor options and containing nicotine (EB Design, SMOK, Hyde, and Vuse). Despite declines in popularity, Black or Hispanic respondents report using JUUL and Puff Bar to a greater extent than other respondents, and vape less frequently than White non-Hispanic respondents regardless of brand. As e-cigarette brands continue to proliferate, monitoring e-cigarette brand selection by race/ethnicity can inform studies of nicotine exposure, polyuse, and health disparities.</p><p><strong>Implications: </strong>Our study demonstrates the importance of research methods to detect rapidly changing patterns of e-cigarette use by race/ethnicity and age. The inclusion of measures capturing brand use can detect evidence of product features and targeted marketing that may have consequences for patterns of tobacco use and nicotine exposure among these groups.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":"849-855"},"PeriodicalIF":3.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142143140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}