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Integrating Use Frequency, Vaping, and Dependence to Characterize Nicotine-Cannabis Co-Use in Young Adults: A Latent Class Analysis. 整合使用频率,电子烟和依赖性来表征年轻人尼古丁-大麻共同使用:潜在类分析。
IF 2.7 2区 医学
Nicotine & Tobacco Research Pub Date : 2026-08-31 DOI: 10.1093/ntr/ntag194
Wura Jacobs, Michael Peck, Maria Parker
{"title":"Integrating Use Frequency, Vaping, and Dependence to Characterize Nicotine-Cannabis Co-Use in Young Adults: A Latent Class Analysis.","authors":"Wura Jacobs, Michael Peck, Maria Parker","doi":"10.1093/ntr/ntag194","DOIUrl":"https://doi.org/10.1093/ntr/ntag194","url":null,"abstract":"<p><strong>Introduction: </strong>Tobacco and cannabis co-use is an increasingly complex public health challenge shaped by rapid expansion of vaping technologies and product diversity. To inform prevention and intervention efforts, behavioral typologies that incorporate use frequency, vaping, dependence/disordered use indicators are needed.</p><p><strong>Methods: </strong>We analyzed pooled 2022-2023 National Survey on Drug Use and Health data from 14,500 U.S. young adults aged 18-29 who reported tobacco/nicotine or cannabis use. Latent class analysis identified subgroups based on past 30-day tobacco use frequency, nicotine vaping frequency, cannabis use frequency, nicotine dependence (Nicotine Dependence Syndrome Scale), and cannabis use disorder (DSM-5 criteria).</p><p><strong>Results: </strong>A four-class model optimally balanced fit and interpretability. The largest subgroup was the nicotine-dominant use class (38.6%), marked by high tobacco use and minimal cannabis involvement. Three distinct co-use classes were identified: low co-use (17.4%), characterized by the lowest levels of tobacco product use, nicotine vaping, and cannabis use and comparatively low nicotine dependence and cannabis use disorder; cannabis-dominant co-use (32.3%), characterized by near-daily cannabis use with relatively low tobacco product use, nicotine vaping, and nicotine dependence; and high-frequency co-use (11.7%), characterized by frequent use of both nicotine products and cannabis and elevated nicotine dependence and cannabis use disorder. Serious psychological distress was associated with nearly twice the risk of cannabis-dominant co-use relative to nicotine-dominant use.</p><p><strong>Conclusion: </strong>Incorporating use frequency, vaping behaviors, and validated dependence and disordered use measures revealed distinct, tobacco-cannabis co-use behavioral phenotypes among young adults. Findings underscore the need for integrated prevention and cessation approaches tailored to heterogeneous co-use patterns.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Socioeconomic, psychological distress, and social norm correlates of youth smoking and vaping: a multilevel pooled cross-sectional analysis. 社会经济、心理困扰和社会规范与青少年吸烟和电子烟的相关性:一项多水平汇集横断面分析。
IF 2.7 2区 医学
Nicotine & Tobacco Research Pub Date : 2026-08-29 DOI: 10.1093/ntr/ntag191
Christopher Cambron, Christine M Steeger
{"title":"Socioeconomic, psychological distress, and social norm correlates of youth smoking and vaping: a multilevel pooled cross-sectional analysis.","authors":"Christopher Cambron, Christine M Steeger","doi":"10.1093/ntr/ntag191","DOIUrl":"10.1093/ntr/ntag191","url":null,"abstract":"<p><strong>Introduction: </strong>Cigarette smoking among youth has continued to decline in recent years as vaping product use has become increasingly popular. Lower socioeconomic status (SES), psychological distress, and exposure to more permissive smoking norms are associated with higher rates of cigarette smoking. It remains unclear the extent to which SES, psychological distress, and smoking norms may represent common correlates for youth smoking and vaping.</p><p><strong>Methods: </strong>The current study estimated pooled, cross-sectional, generalized linear mixed models to examine associations between SES, psychological distress, and smoking norms with lifetime and recent smoking and vaping among statewide samples of Utah youth from 2011 to 2019 (N=231,972). Moderation analyses investigated changes in the strength of association between SES, psychological distress, and smoking norms with outcomes over time.</p><p><strong>Results: </strong>Lower area-level SES was significantly associated with increased odds of smoking and reduced odds of vaping while higher household SES was significantly associated with decreased odds of both smoking and vaping. Greater psychological distress and more permissive smoking norms were associated with increased odds of both smoking and vaping. Moderation analyses indicated that, over time, the association between SES and vaping strengthened, the effects of psychological distress on smoking and vaping strengthened, and the effects of smoking norms on smoking and vaping weakened.</p><p><strong>Conclusions: </strong>Results of this study suggest that SES, psychological distress, and smoking norms represent common correlates for smoking and vaping. Interventions to improve health literacy, reduce psychological distress, improve health literacy, and influence social norms may reduce long-term tobacco-related health risks.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148857540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of cessation aids on sustained quitting and weight gain among adults with a quit attempt in the PATH study. 在PATH研究中,戒烟辅助对持续戒烟和体重增加的影响。
IF 2.7 2区 医学
Nicotine & Tobacco Research Pub Date : 2026-08-29 DOI: 10.1093/ntr/ntag189
Cara M Murphy, Alexander W Sokolovsky, Cameron Cooper, Lauren Micalizzi
{"title":"The impact of cessation aids on sustained quitting and weight gain among adults with a quit attempt in the PATH study.","authors":"Cara M Murphy, Alexander W Sokolovsky, Cameron Cooper, Lauren Micalizzi","doi":"10.1093/ntr/ntag189","DOIUrl":"10.1093/ntr/ntag189","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to compare cessation and weight gain among US adults in Wave 6 of the PATH Study.</p><p><strong>Methods: </strong>Participants reporting a past year quit attempt (n = 2454) were grouped by cessation aid used: (1) medication (Rx), (2) nicotine replacement therapy (NRT), (3) e-cigarettes (EC), (4) Rx + NRT, (5) Rx or NRT plus EC, or (6) None/no aid. Past-year smoking cessation and cessation-related eating/weight gain were regressed onto cessation aid, adjusting for relevant covariates. The impact of flavor was also tested among those using e-cigarettes to quit.</p><p><strong>Results: </strong>In adjusted models, those using e-cigarettes were less likely to quit than those using no aid. Among successful quitters, all cessation aids, except exclusive e-cigarette use, were associated with increased eating/weight gain in unadjusted models, but not in adjusted models. Use of novel e-cigarette flavors did not increase cessation likelihood.</p><p><strong>Conclusions: </strong>Commonly used cessation aids did not improve cessation outcomes or prevent weight gain among US adults in real-world quit attempts. People using e-cigarettes to quit were less successful and had comparable weight gain to those using no aid, with no impact of e-cigarette flavor, suggesting additional support may be needed for people trying to use e-cigarettes to quit.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148857521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Relationship Between Racial Bullying Victimization and Adolescent E-cigarette Use in California. 探索种族欺凌受害与加州青少年电子烟使用之间的关系。
IF 2.7 2区 医学
Nicotine & Tobacco Research Pub Date : 2026-08-28 DOI: 10.1093/ntr/ntag195
Andrew H Vu, Brittany N Morey, David S Timberlake, Andrew Odegaard, Sora P Tanjasiri
{"title":"Exploring the Relationship Between Racial Bullying Victimization and Adolescent E-cigarette Use in California.","authors":"Andrew H Vu, Brittany N Morey, David S Timberlake, Andrew Odegaard, Sora P Tanjasiri","doi":"10.1093/ntr/ntag195","DOIUrl":"https://doi.org/10.1093/ntr/ntag195","url":null,"abstract":"<p><strong>Introduction: </strong>Higher prevalence of adolescent e-cigarette use among racially marginalized communities remains an issue in the United States. Experiences of racial bullying victimization may contribute to increased vulnerability to e-cigarette use and initiation. Although previous studies have looked at bullying and traditional tobacco products, fewer studies have examined the relationship between bullying and e-cigarette use, especially within racial and ethnic groups.</p><p><strong>Methods: </strong>We used data from the 2021-2022 California Healthy Kids Survey, a survey of 7th, 9th, and 11th-grade public school adolescents (ages 12-17) in California. Lifetime and current e-cigarette use were self-reported outcomes. Racial bullying victimization was assessed by self-report of harassment or bullying due to race or ethnicity. We used multivariable logistic regressions stratified by race and ethnicity to examine associations between racial bullying victimization and e-cigarette use, controlling for grade, gender identity, parental education, and clustering within schools.</p><p><strong>Results: </strong>Across all races and ethnic groups in the full analytic sample, adolescents had higher odds of lifetime and current e-cigarette use when exposed to racial bullying. Elevated odds were most pronounced among Native Hawaiian or Other Pacific Islander, American Indian or Alaska Native, and Asian adolescents, though confidence intervals overlapped with non-Hispanic White adolescents. Non-Hispanic White and Hispanic adolescents exhibited lower but still increased odds.</p><p><strong>Conclusion: </strong>Racial bullying victimization is consistently associated with increased likelihood of adolescent e-cigarette use across racial and ethnic groups. These findings highlight the potential importance of addressing race-based bullying to reduce disparities in adolescent e-cigarette use.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perceptions of Harm, Addiction, and Cessation Support among People Who Use Non-Cigarette Tobacco Products in England: A Qualitative Study. 在英国,使用非卷烟烟草产品的人对危害、成瘾和戒烟支持的认知:一项定性研究。
IF 2.7 2区 医学
Nicotine & Tobacco Research Pub Date : 2026-08-28 DOI: 10.1093/ntr/ntag193
Eve Taylor, Harry Tattan-Birch, Jamie Brown, Lion Shahab, Sharon Cox, Masuma Mishu, Katherine East, Hazel Cheeseman, Sarah Jackson
{"title":"Perceptions of Harm, Addiction, and Cessation Support among People Who Use Non-Cigarette Tobacco Products in England: A Qualitative Study.","authors":"Eve Taylor, Harry Tattan-Birch, Jamie Brown, Lion Shahab, Sharon Cox, Masuma Mishu, Katherine East, Hazel Cheeseman, Sarah Jackson","doi":"10.1093/ntr/ntag193","DOIUrl":"https://doi.org/10.1093/ntr/ntag193","url":null,"abstract":"<p><strong>Introduction: </strong>England provides comprehensive support for cigarette smoking cessation, and some services also assist people who use non-cigarette tobacco products (e.g., cigars/cigarillos, shisha, and chewing tobacco). Little is known about whether users are interested in quitting, their willingness to engage with cessation services, or beliefs shaping these intentions.</p><p><strong>Methods: </strong>Five semi-structured focus groups and two interviews were conducted with adults who use non-cigarette tobacco in England (N=25). Topic guides covered harm perceptions, interest in quitting, and knowledge of, interest in, and barriers to using services for quitting. Data were prepared and analysed using iterative categorisation and abductive thematic analysis.</p><p><strong>Results: </strong>Participants often recognised health harms and some reported experiencing addiction. Many participants had never considered quitting, whereas others described multiple attempts. Interest in quitting was shaped by perceptions of addiction and socio-cultural roles of non-cigarette tobacco. Participants were rarely asked about non-cigarette tobacco use by healthcare professionals and were unaware of whether cessation services could support non-cigarette tobacco use. Although some expressed interest in using services, many preferred to rely on willpower and online support, or felt insufficiently dependent to use services. Participants suggested improving awareness of support through community outreach and routinely asking about all forms of tobacco use in healthcare settings.</p><p><strong>Conclusions: </strong>People who use non-cigarette tobacco show varied interest in quitting, which appears to be shaped by perceived addiction and social factors. Limited awareness of cessation support and low engagement by healthcare professionals may represent missed opportunities for intervention.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Awareness and use of oral tobacco and nicotine products among people who smoke or recently stopped smoking: Descriptive findings from the 2024 EASE/ITC New Zealand Survey. 吸烟或最近戒烟的人对口服烟草和尼古丁产品的认识和使用:2024年EASE/ITC新西兰调查的描述性结果。
IF 2.7 2区 医学
Nicotine & Tobacco Research Pub Date : 2026-08-27 DOI: 10.1093/ntr/ntag190
Jude Ball, Jane Zhang, Janet Hoek, James Stanley, Andrew Waa, El-Shadan Tautolo, Thomas Agar, Anne C K Quah, Geoffrey T Fong, Richard Edwards
{"title":"Awareness and use of oral tobacco and nicotine products among people who smoke or recently stopped smoking: Descriptive findings from the 2024 EASE/ITC New Zealand Survey.","authors":"Jude Ball, Jane Zhang, Janet Hoek, James Stanley, Andrew Waa, El-Shadan Tautolo, Thomas Agar, Anne C K Quah, Geoffrey T Fong, Richard Edwards","doi":"10.1093/ntr/ntag190","DOIUrl":"https://doi.org/10.1093/ntr/ntag190","url":null,"abstract":"<p><strong>Introduction: </strong>Aotearoa New Zealand (NZ) disallows sales of oral tobacco and nicotine products, although importation for personal use is permitted. The government proposes legalising sales, claiming this will aid smoking cessation among \"older, long-term smokers.\" We examined awareness and use of tobacco-free oral nicotine products (ONPs), snus, and other oral tobacco products among adults who smoke or who recently stopped smoking.</p><p><strong>Methods: </strong>We analysed Wave 5 (2024) data from the EASE/International Tobacco Control (ITC) NZ Survey (N=1,371) of adults who smoke or recently stopped smoking. We examined prevalence of awareness, ever, and current (at least monthly) use of oral tobacco and nicotine products, overall and by demographic factors and smoking status/cessation intentions.</p><p><strong>Results: </strong>Awareness was 41.3% (95% confidence interval 37.7, 45.0) for ONPs, 31.5% (28.1, 35.2) for snus, and 70.2% (66.6, 73.5) for other oral tobacco products. Ever use was 12.5% (10.5, 14.8), 7.0% (5.5, 8.8), and 11.6% (9.6, 14.0) respectively. Current use was 4.1% (3.1, 5.6), 2.4% (1.5, 3.6), and 2.6% (1.9, 3.7) respectively. Weighted point estimates for awareness and use of snus and any oral product overall were lower among adults aged ≥45 than those aged 18-24 or 25-44. Current use of oral products was 5.8% (3.3, 10.1) among those who smoked daily with no intention to stop.</p><p><strong>Conclusions: </strong>Current policy settings allow meaningful levels of oral product use in NZ. Use is uncommon among adults aged ≥45 years and occurs among people without cessation intentions, highlighting the risk that use may complement rather than replace smoking.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148840889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Smoking and vaping trends among active-duty U.S. Navy and Marine Corps personnel: results from the Annual Periodic Health Assessment, 2017-2021. 美国海军和海军陆战队现役人员吸烟和电子烟趋势:2017-2021年年度定期健康评估结果
IF 2.7 2区 医学
Nicotine & Tobacco Research Pub Date : 2026-08-26 DOI: 10.1093/ntr/ntag188
James K Romine, Amber L Dougherty, Eyal Oren, Giovanni Appolon, Andrew J MacGregor
{"title":"Smoking and vaping trends among active-duty U.S. Navy and Marine Corps personnel: results from the Annual Periodic Health Assessment, 2017-2021.","authors":"James K Romine, Amber L Dougherty, Eyal Oren, Giovanni Appolon, Andrew J MacGregor","doi":"10.1093/ntr/ntag188","DOIUrl":"https://doi.org/10.1093/ntr/ntag188","url":null,"abstract":"<p><strong>Introduction: </strong>This study compared annual prevalences of traditional cigarette smoking versus e-cigarette vaping among active-duty U.S. Navy or Marine Corps personnel from 2017 to 2021.</p><p><strong>Methods: </strong>Trends were estimated using the annual Periodic Health Assessment (PHA), a standardized evaluation of medical readiness for military duties. We estimated crude and age-adjusted prevalences of tobacco-use type for each annual PHA and plotted linear trends.</p><p><strong>Results: </strong>The study included 496,079 active-duty service members who completed ≥1 PHA between 2017 and 2021. Trends of cigarette smoking were inversely related to e-cigarette vaping; as smoking decreased, vaping increased. The age-adjusted annual prevalence of cigarette smoking (single-product use) declined from 7.7% to 4.2%. In contrast, the age-adjusted annual prevalence of e-cigarette vaping increased from 2.8% to 8.3%.</p><p><strong>Conclusions: </strong>By the end of the study period, single-product use of e-cigarettes (vaping) was nearly twice as prevalent as cigarette smoking-a striking reversal in the dominant form of tobacco use within 5 years. This finding illustrates how rapidly vaping has supplanted traditional smoking among Navy and Marine Corps personnel, marking a fundamental shift in nicotine consumption with implications for military health monitoring and tobacco cessation programs.</p><p><strong>Implications: </strong>The study shows e-cigarette vaping rapidly supplanting traditional cigarette smoking among Navy and Marine Corps personnel. It marks a fundamental shift in nicotine consumption with implications for military health monitoring and tobacco cessation programs. Historically, military personnel have been high-risk for cigarette addiction, yet the uptake of e-cigarettes (vaping) is relatively new. Estimating trends of nicotine-use is important for allocating resources and prioritizing cessation interventions or other programs.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148818541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of very low nicotine cigarettes on cannabis and alcohol use during a 12-week clinical trial. 在为期12周的临床试验中,极低尼古丁香烟对大麻和酒精使用的影响。
IF 2.7 2区 医学
Nicotine & Tobacco Research Pub Date : 2026-08-24 DOI: 10.1093/ntr/ntag070
Emily E Hackworth, Jacob Lastovich, Dana Mowls Carroll, Xianghua Luo, Jennifer Tidey, Suzanne M Colby, Andrew A Strasser, F Joseph McClernon, Neal Benowitz, Rachel Denlinger-Apte, Eric C Donny, Dorothy K Hatsukami
{"title":"The impact of very low nicotine cigarettes on cannabis and alcohol use during a 12-week clinical trial.","authors":"Emily E Hackworth, Jacob Lastovich, Dana Mowls Carroll, Xianghua Luo, Jennifer Tidey, Suzanne M Colby, Andrew A Strasser, F Joseph McClernon, Neal Benowitz, Rachel Denlinger-Apte, Eric C Donny, Dorothy K Hatsukami","doi":"10.1093/ntr/ntag070","DOIUrl":"10.1093/ntr/ntag070","url":null,"abstract":"<p><strong>Introduction: </strong>In January 2025, the US Food and Drug Administration announced a proposed rule for a reduced nicotine standard (RNS) in cigarettes. Evidence suggests that the use of very low nicotine content (VLNC) cigarettes decreases cigarette use and tobacco toxicant exposure; however, unintended consequences, such as a resulting increase in use of other reinforcing substances (eg, cannabis, alcohol), are a concern. This secondary analysis aims to provide an ecologically valid assessment of the impact of RNS on alcohol and cannabis use.</p><p><strong>Methods: </strong>During 2018-2022, participants were randomized to VLNC or normal nicotine content cigarettes for 12 weeks. All participants had access to non-combusted nicotine products through an experimental tobacco marketplace. We examined the association between cigarette condition and alcohol or cannabis use, among participants reporting (1) use of each substance at baseline, to examine whether condition impacted frequency of use and (2) non-use at baseline, to examine differences in uptake during the study.</p><p><strong>Results: </strong>Study condition did not affect frequency of alcohol or cannabis use among those reporting baseline use (mean differencealcohol = 0.90, 95% CI, -5.33 to 7.03; mean differencecannabis = 0.87, 95% CI, -8.00 to 9.24), nor did it affect the frequency among those reporting baseline non-use (mean differencealcohol = 0.83, 95% CI, -0.14 to 1.80; mean differencecannabis = -1.92, 95% CI, -5.02 to 1.19) or likelihood of uptake (adjusted odds ratio [AOR]alcohol = 1.09, 95% CI, 0.85 to 1.38; AORcannabis = 1.20, 95% CI, 0.97 to 1.45).</p><p><strong>Conclusions: </strong>This study adds to the evidence that that unintended consequences of an RNS as it relates to significant increases in alcohol or cannabis use among people who smoke are unlikely.</p><p><strong>Implications: </strong>This secondary analysis provides an ecologically valid assessment of the impact of a reduced nicotine standard on alcohol and cannabis use. Results add to the evidence suggesting that increases in alcohol or cannabis use as a consequence of a reduced nicotine standard are unlikely, providing further evidence that implementing a reduced nicotine standard would have public health benefit.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":"1604-1609"},"PeriodicalIF":2.7,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147618899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association between self-reported vaping and the human oral microbiome: a systematic review. 自我报告的尼古丁雾化与人类口腔微生物群之间的关系:一项系统综述。
IF 2.7 2区 医学
Nicotine & Tobacco Research Pub Date : 2026-08-24 DOI: 10.1093/ntr/ntag103
Joseph Sidhom, Sudheer Babu Balla, Santosh Kumar Tadakamadla, Jyothi Tadakamadla
{"title":"The association between self-reported vaping and the human oral microbiome: a systematic review.","authors":"Joseph Sidhom, Sudheer Babu Balla, Santosh Kumar Tadakamadla, Jyothi Tadakamadla","doi":"10.1093/ntr/ntag103","DOIUrl":"10.1093/ntr/ntag103","url":null,"abstract":"<p><strong>Introduction: </strong>Vapes, with or without nicotine, have experienced a rise in their popularity, and our understanding of how vapes affect our oral microbiome remains to be reviewed. This systematic review explores whether the use of vapes is associated with measurable alterations in the diversity and taxonomic composition of the oral microbiome compared to non-vapers or conventional cigarette smokers.</p><p><strong>Methods: </strong>A comprehensive and systematic search of 6 databases was meticulously conducted, covering published literature up to the end of August 2024. The data was then extracted and underwent a qualitative analysis. Studies' risk of bias was assessed using Newcastle Ottawa Scale. Eligible studies needed to have a comparison group of either non-smokers or tobacco users or both and a group of sole e-cigarette users.</p><p><strong>Results: </strong>The search yielded 18 articles, with sixteen being cross-sectional and the remaining two were cohort studies. There were 1418 participants across the studies, ranging from 30-125 participants in each study. Majority of the included literature indicated e-cigarettes can alter the taxonomic composition and diversity of their user's oral microbiome.</p><p><strong>Conclusions: </strong>Vaping was found to be associated with changes in oral microbiome. Since, the majority of the existing literature relied on self-reporting to see if participants were sole vapers, and mainly focused on bacterial genera, the exact impact of these changes are difficult to ascertain. However, the existing literature demonstrates a relationship in a few bacterial genera associated with periodontal disease among e-cigarette users, highlighting the need for further comprehensive studies with sound methodological approach to recruit sole e-cigarette users.</p><p><strong>Implications: </strong>This study concludes that vapes do have a demonstratable impact on the oral microbiome that is unique to vapes. E-cigarette use may be associated with an increase periodontal pathogens which may predispose e-cigarette users to worse periodontal disease, however, further research is required.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":"1480-1488"},"PeriodicalIF":2.7,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13500349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147949004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to letter "misleading incomplete results about dual use when using e-cigarettes as cessation aid": taking stock of the evidence. 对“使用电子烟作为戒烟辅助时双重用途的误导性不完整结果”的回复:评估证据。
IF 2.7 2区 医学
Nicotine & Tobacco Research Pub Date : 2026-08-24 DOI: 10.1093/ntr/ntag072
Angela S Attwood
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