Nordic Journal of Psychiatry最新文献_第7页

Somatic health perception among in-patients with severe mental illness: a comparison of self-rated and clinically assessed health. 重度精神疾病住院患者的躯体健康感知：自我评估与临床评估的比较

IF 1.5 4区医学

Nordic Journal of Psychiatry Pub Date : 2026-01-01 Epub Date: 2025-11-04 DOI: 10.1080/08039488.2025.2582163

Nikoline Busk, Christian Jentz, Morten Deleuran Terkildsen, Harry Kennedy, Anneli Sandbæk, Anette Andersen, Lisbeth Uhrskov Sørensen

{"title":"Somatic health perception among in-patients with severe mental illness: a comparison of self-rated and clinically assessed health.","authors":"Nikoline Busk, Christian Jentz, Morten Deleuran Terkildsen, Harry Kennedy, Anneli Sandbæk, Anette Andersen, Lisbeth Uhrskov Sørensen","doi":"10.1080/08039488.2025.2582163","DOIUrl":"10.1080/08039488.2025.2582163","url":null,"abstract":"Purpose: To investigate somatic health burden and self-rated health (SRH) among forensic psychiatric (FP) patients and the concordance between these two health measurements. Additionally, the study evaluates how different binary groupings of SRH responses impact concordance.Methods: In a cross-sectional study, 67 inpatients from two Danish forensic psychiatric hospitals were assessed. SRH was measured using a single-item question from the validated and widely used SF-12 scale, and clinical evaluation was performed by a general physician using the Clinical Frailty Scale (CFS). SRH responses were dichotomised in two different ways to test concordance with clinical assessment, and detailed somatic health data were collected from consultations with health care professionals and patient records.Results: Seventy-nine percent of FP patients assessed their own health as \"good\" or better despite the presence of risk factors such as history of smoking (median pack years = 20) and 25% having hypertension, 84% being overweight, and 55% having metabolic syndrome when assessed by a physician. We found a total of 195 somatic diagnoses with no clear trend in either diagnosis or organ system. Regardless of grouping, concordance between self-reported health and clinician-rated CFS remained low, ranging from 58 to 61%.Conclusion: This study reveals discrepancies between forensic psychiatric patients' subjective and clinically assessed health. The findings underscore the need to interpret SRH with caution in populations with severe mental illness, where discrepancies between SRH, physician-rated health and diagnoses burden are pronounced. Clinicians and researchers should approach SRH critically to avoid underestimating patients' health risks.","PeriodicalId":19201,"journal":{"name":"Nordic Journal of Psychiatry","volume":" ","pages":"18-26"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145438596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristics of people who died by suicide in a hospital district providing open dialogue-based psychiatric services: a nationwide cluster analysis. 在提供公开对话精神科服务的医院区自杀的人的特征：一项全国性聚类分析。

IF 1.5 4区医学

Nordic Journal of Psychiatry Pub Date : 2026-01-01 Epub Date: 2025-09-06 DOI: 10.1080/08039488.2025.2548235

Tomi Bergström, Selma Gaily-Luoma, Mia Kurtti, Jouko Miettunen, Timo Partonen, Jaana Suvisaari, Jyri J Taskila, Antti Alaräisänen

{"title":"Characteristics of people who died by suicide in a hospital district providing open dialogue-based psychiatric services: a nationwide cluster analysis.","authors":"Tomi Bergström, Selma Gaily-Luoma, Mia Kurtti, Jouko Miettunen, Timo Partonen, Jaana Suvisaari, Jyri J Taskila, Antti Alaräisänen","doi":"10.1080/08039488.2025.2548235","DOIUrl":"10.1080/08039488.2025.2548235","url":null,"abstract":"Objective: Suicide rates vary regionally in Finland, with Western Lapland (WL) being a high-risk area. WL is also known for developing the Open Dialogue (OD)-based psychiatric services. This study aimed to compare the characteristics of suicide cases in WL to the rest of Finland to better understand the elevated suicide rate.Materials and methods: Register-based data on all suicides (n = 4502) in Finland from 2017 to 2022 were used for clustering of demographic and clinical characteristics. Principal Component Analysis was applied for dimensionality reduction, followed by K-means clustering. Logistic regression was used to examine the association between WL and the clusters.Results: WL recorded 66 suicides, with an average annual rate of 18 per 100,000, compared to 13.5 per 100,000 in the rest of Finland. Five clusters were identified from national data: (1) younger men with low service use, (2) individuals with repeated suicide attempts likely dying by self-poisoning, (3) socially integrated men with internalizing disorders, (4) older men with low service use more likely dying by firearm, and (5) individuals treated for severe mental disorders. WL suicides were more likely to belong to Cluster 4 (OR: 2, 95%CI: 1.2-3.3), with no other significant associations.Conclusions: The Finnish hospital district providing OD-based psychiatric services had a higher suicide rate among older men using firearms with lower service contact, emphasizing the need for tailored prevention strategies. There was no indication that the region's elevated suicide rate could be explained by a higher rate of suicides in OD service users.","PeriodicalId":19201,"journal":{"name":"Nordic Journal of Psychiatry","volume":" ","pages":"2-9"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early-onset trans-sensitive therapy as part of gender dysphoria care-a pilot randomized controlled trial. 早发性跨敏感疗法作为性别焦虑症治疗的一部分——一项随机对照试验。

IF 1.5 4区医学

Nordic Journal of Psychiatry Pub Date : 2026-01-01 Epub Date: 2025-11-23 DOI: 10.1080/08039488.2025.2589850

Helga Mannerström, Henrik Mannerström, Mia Holi, Noor Assad, Katinka Tuisku, Niina Puustinen

{"title":"Early-onset trans-sensitive therapy as part of gender dysphoria care-a pilot randomized controlled trial.","authors":"Helga Mannerström, Henrik Mannerström, Mia Holi, Noor Assad, Katinka Tuisku, Niina Puustinen","doi":"10.1080/08039488.2025.2589850","DOIUrl":"10.1080/08039488.2025.2589850","url":null,"abstract":"Objective: Psychosocial support plays a crucial role in gender-affirming treatments. This pilot randomized controlled trial, conducted in Finland, aimed to determine whether early-onset psychotherapy affects the mental distress and well-being of individuals seeking gender-affirming treatment.Methods: Participants (N = 58) were enrolled from individuals seeking gender-affirming treatment referred to the Gender Identity Clinic at Helsinki University Hospital. Participants were randomized into two groups: early therapy or the standard evaluation process. Evaluations using the General Health Questionnaire-12 items (GHQ-12) and Short Warwick-Edinburgh Mental Well-Being Scale (SWEMWBS) were conducted at baseline and at the end of the evaluation period, approximately one year after enrollment. The effectiveness of the treatment was assessed with analysis of covariance (ANCOVA). In addition, participants reported their experiences through written and oral feedback.Results: The group that received early-onset psychotherapy showed a significant change in GHQ-12 score compared with the control (p < 0.05). The estimated effect of the intervention was a change of -4.0 (95% Cl -7.9, -0.2), indicating lower mental distress. According to feedback collected from participants, psychotherapeutic support was perceived as significant and was particularly desired at the beginning of the gender-affirming process, where the need for self-reflection was greatest. Additionally, psychosocial support was also desired to aid the transition process.Conclusions: A complete RCT study with larger intervention and control groups is needed to make definitive conclusions about the effectiveness of early- onset trans- sensitive therapy. However, the results of this pilot trial support the continuation of the current clinical use of trans-sensitive psychotherapy in Finland.","PeriodicalId":19201,"journal":{"name":"Nordic Journal of Psychiatry","volume":" ","pages":"49-58"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145588206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measuring attitudes toward self-harm among mental health care staff: psychometric evaluation of the Self-Harm Antipathy Scale (SHAS) in Denmark. 测量心理保健人员对自我伤害的态度：丹麦自我伤害反感量表（SHAS）的心理测量评估

IF 1.5 4区医学

Nordic Journal of Psychiatry Pub Date : 2026-01-01 Epub Date: 2025-11-27 DOI: 10.1080/08039488.2025.2589478

Kristine Høst Poulsen, Bo Bach, Carsten Hjorthøj, Erik Simonsen, Stephen Fitzgerald Austin, Mickey T Kongerslev

{"title":"Measuring attitudes toward self-harm among mental health care staff: psychometric evaluation of the Self-Harm Antipathy Scale (SHAS) in Denmark.","authors":"Kristine Høst Poulsen, Bo Bach, Carsten Hjorthøj, Erik Simonsen, Stephen Fitzgerald Austin, Mickey T Kongerslev","doi":"10.1080/08039488.2025.2589478","DOIUrl":"10.1080/08039488.2025.2589478","url":null,"abstract":"Background: Negative attitudes among mental health professionals toward individuals who self-harm can impact the quality of care and contribute to antipathy and stigma. This study aimed to investigate the psychometric properties of a Danish version of the Self-Harm Antipathy Scale (SHAS-DR), designed to measure mental health professions attitudes toward patients who self-harm.Methods: The SHAS-D was administered to 261 mental health professionals. Confirmatory factor analysis (CFA) was used to examine dimensionality and structural validity. Internal consistency was evaluated using Cronbach's alpha reliability and McDonald's omega coefficients, and discriminant validity was assessed via factor intercorrelations.Results: Neither a unidimensional global factor nor the originally proposed six-factor model, based on all 30 items, were supported. Consistent with a previous study, a 17-item three-factor solution and a 19-item five-factor solution showed acceptable model fit. Internal consistency was acceptable for most subscale scores. The three-factor model was superior to the five-factor model in terms of internal consistency and discriminant validity.Conclusions: The 17-item form of the SHAS-DR, capturing three subscales, is a structurally valid and reliable tool for assessing attitudes toward self-harm in Danish mental health care. The three factors of 'Sympathy and Support', 'Judgmental Perception', and 'Acceptance and Understanding' point to central areas of antipathy and may be important targets for future training and stigma-reduction efforts among mental health care staff working with patients who engage in self-harm.","PeriodicalId":19201,"journal":{"name":"Nordic Journal of Psychiatry","volume":" ","pages":"42-48"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145636777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic accuracy of the alcohol use disorders identification test (AUDIT) in Swedish young adult outpatients in general psychiatry. 酒精使用障碍鉴定试验（AUDIT）在瑞典普通精神科青年门诊患者中的诊断准确性

IF 1.5 4区医学

Nordic Journal of Psychiatry Pub Date : 2026-01-01 Epub Date: 2025-11-06 DOI: 10.1080/08039488.2025.2584271

Sofia Lenninger, Johan Isaksson, Mia Ramklint, Adriana Ramirez

{"title":"Diagnostic accuracy of the alcohol use disorders identification test (AUDIT) in Swedish young adult outpatients in general psychiatry.","authors":"Sofia Lenninger, Johan Isaksson, Mia Ramklint, Adriana Ramirez","doi":"10.1080/08039488.2025.2584271","DOIUrl":"10.1080/08039488.2025.2584271","url":null,"abstract":"Aims: The Alcohol Use Disorders Identification Test (AUDIT) is a widely used screening instrument for harmful alcohol use. Comorbidity between alcohol use disorders and other mental disorders is common, but there is a shortage of studies investigating AUDIT's diagnostic accuracy in young adult psychiatric patients. The aim of this study was to examine AUDIT's diagnostic accuracy and psychometric properties in young adult psychiatric outpatients.Methods: In data from two samples of young adults (18-25 years) from general psychiatric outpatient clinics in Sweden, recruited in 2002-2003 (n = 197) and 2012-2016 (n = 283) psychiatric diagnoses were assessed using the Structured Clinical Interview for DSM-IV, axis I disorders, clinical version (SCID-I-CV) or the Mini International Neuropsychiatric Interview (MINI 6.0). Internal consistency of AUDIT, sensitivity, specificity, positive and negative predictive values (PPV and NPV), receiver operator characteristic (ROC) curves, and area under the curve (AUC) were calculated.Results: The internal consistency of AUDIT was acceptable (Cronbach's alpha = 0.76). For the samples combined the optimal cut-off was 10, sensitivity 87% and specificity 82%, PPV 0.28 and NPV 0.99. For Sample 2002-2003, the optimal cut-off point was nine For Sample 2012-2016, the optimal cut-off point was 10. ROC curves are presented, with an AUC of 0.88 (95% CI= 0.81-0.95) for both samples combined, 81.1% for Sample 2002-2003 (95% CI = 0.63-0.99) and an AUC of 90.6% for Sample 2012-2016 (95% Cl = 0.85-0.96).Conclusion: The full version of AUDIT is a reliable and valid screening instrument for alcohol use disorders, as shown in two samples of young adult psychiatric outpatients.","PeriodicalId":19201,"journal":{"name":"Nordic Journal of Psychiatry","volume":" ","pages":"27-34"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145452506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alcohol use, daily smoking, clozapine use and psychiatric symptom profile in persons with schizophrenia spectrum disorder. 精神分裂症谱系障碍患者的酒精使用、每日吸烟、氯氮平使用和精神症状概况

IF 1.5 4区医学

Nordic Journal of Psychiatry Pub Date : 2026-01-01 Epub Date: 2025-11-30 DOI: 10.1080/08039488.2025.2590578

Jonna Levola, Sari Lång-Tonteri, Solja Niemelä, Jaana Suvisaari, Saana Eskelinen

{"title":"Alcohol use, daily smoking, clozapine use and psychiatric symptom profile in persons with schizophrenia spectrum disorder.","authors":"Jonna Levola, Sari Lång-Tonteri, Solja Niemelä, Jaana Suvisaari, Saana Eskelinen","doi":"10.1080/08039488.2025.2590578","DOIUrl":"10.1080/08039488.2025.2590578","url":null,"abstract":"Purpose: Alcohol use and daily smoking are common among individuals with schizophrenia spectrum disorder but less is known about their relationship to psychotic symptom profile and severity, and how clozapine use may affect this relationship.Materials and methods: Among a clinical sample of 276 Finnish outpatients with schizophrenia spectrum disorder (68.8% schizophrenia), the Brief Psychiatric Rating Scale (BPRS) and the Scale for the Assessment of Negative Symptoms (SANS) were used to determine severity of psychotic symptoms. Information regarding alcohol use was collected with questionnaires including the Alcohol Use Disorders Identification Test-Concise (AUDIT-C) and information of smoking. Associations between psychiatric symptoms and substance use were studied using linear regression separately for those with or without clozapine use. Age, gender, marital status, living situation and education were adjusted for in the final analyses.Results: In the multivariable models, heavy alcohol use and binge drinking were less frequent among participants with clozapine use (n = 115) compared to those without (n = 161). Differences in some symptoms were observed in bivariate analyses when comparing the participants with and without heavy or binge drinking, or daily smoking. Heavy and binge drinking were associated with more severe grandiosity symptoms even after controlling for potential confounders. Daily smoking was associated with more severe hostility, elated mood, unusual thought content and uncooperativeness, but less severe emotional withdrawal.Conclusions: Symptom profiles and severity differed according to alcohol use or smoking. The possible explanations for the role of clozapine are discussed.","PeriodicalId":19201,"journal":{"name":"Nordic Journal of Psychiatry","volume":" ","pages":"66-73"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145636701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Open Dialogue: innovation without evidence? 公开对话：没有证据的创新？

IF 1.5 4区医学

Nordic Journal of Psychiatry Pub Date : 2026-01-01 Epub Date: 2025-10-31 DOI: 10.1080/08039488.2025.2579615

Merete Nordentoft

引用次数: 0

The power of social capital-social capital and depressive symptoms in the Northern Finland Birth Cohort 1966. 社会资本的力量-社会资本与芬兰北部出生队列的抑郁症状1966。

IF 1.5 4区医学

Nordic Journal of Psychiatry Pub Date : 2026-01-01 Epub Date: 2025-10-28 DOI: 10.1080/08039488.2025.2577344

Johanna Kemppainen, Paula Pesonen, Jouko Miettunen, Markku Timonen

{"title":"The power of social capital-social capital and depressive symptoms in the Northern Finland Birth Cohort 1966.","authors":"Johanna Kemppainen, Paula Pesonen, Jouko Miettunen, Markku Timonen","doi":"10.1080/08039488.2025.2577344","DOIUrl":"10.1080/08039488.2025.2577344","url":null,"abstract":"Background: Social capital theory is predominantly built around social networks, relationships, and functions of society. Social capital dimensions have been found to be inversely associated with depressive symptoms. This study aimed to investigate the association between cognitive and structural dimensions of social capital and depressive symptoms (outcome variable) at an epidemiological level.Methods: Social capital consisted of cognitive (actual support, emotional support and generalized trust) and structural (taking care of family members) dimensions. Depressive symptoms were calculated using the Hopkins Symptoms Checklist- 15. Data used was derived from the Northern Finland Birth Cohort 1966, utilizing a sample of 46-year-old participants (N = 6522). The study used cross-sectional design. Binary logistic regression analyses were used to explore the association between these dimensions of social capital and depressive symptoms after adjusting for gender, education level, and marital status.Results: Cognitive social capital variables were associated with depressive symptoms: those who received 'not at all' emotional or actual support from their partners were significantly more likely to exhibit depressive symptoms (odd ratios (OR) being 2.04 (95% CI = 1.57, 2.65) and 2.29 (95% CI = 1.76, 2.98), respectively) than those whose partners supported them a lot/quite a lot. Furthermore, those having extra low generalized trust had over 7-fold (OR = 7.55, 95% CI= 5.42, 10.53) increased risk of exhibiting depressive symptoms. Structural social capital was not associated with depressive symptoms.Conclusions: A significant association between cognitive social capital and depressive symptoms was found, suggesting that social capital may play a significant role in the trajectory of depressive symptoms.","PeriodicalId":19201,"journal":{"name":"Nordic Journal of Psychiatry","volume":" ","pages":"10-17"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145378012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of sex and depressive symptoms on diagnostic delay of attention deficit hyperactivity disorder in adolescent psychiatric patients. 性别和抑郁症状对青少年精神病患者注意缺陷多动障碍诊断延迟的影响

IF 1.5 4区医学

Nordic Journal of Psychiatry Pub Date : 2026-01-01 Epub Date: 2025-11-18 DOI: 10.1080/08039488.2025.2588759

Iordana Ntini, Kent Nilsson, Mia Ramklint, Gustafsson Sa, Karin Sonnby

{"title":"Influence of sex and depressive symptoms on diagnostic delay of attention deficit hyperactivity disorder in adolescent psychiatric patients.","authors":"Iordana Ntini, Kent Nilsson, Mia Ramklint, Gustafsson Sa, Karin Sonnby","doi":"10.1080/08039488.2025.2588759","DOIUrl":"10.1080/08039488.2025.2588759","url":null,"abstract":"Background: Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in adolescence resulting in functional impairment that often persist to adulthood. Girls seem to be diagnosed with ADHD later in life than boys and more often have a comorbid major depressive disorder (MDD). It has been suggested that comorbidity with MDD can interfere with early identification of ADHD.Aims: The aim of the study was to investigate the diagnostic delay for boys and girls with ADHD in child and adolescent outpatient settings as well the interference of self-reported symptoms of MDD.Methods: Adolescent psychiatric outpatients were assessed with DSRS-A Screener (version of Depression Self-Rating Scale for Adolescents) at intake. Diagnostic delay for ADHD was estimated with Kaplan-Meier survival curve with separated analysis for boys/girls and for negative/positive MDD screening. Cox regression analysis was used to examine the association of sex and MDD screening.Results: Diagnostic delay for N = 252 (41% boys, mean age =15.23 years) was 3.5 years, 1.4 for boys and 4.9 for girls (p = 0.004). Positive MDD screening was associated with prolonged diagnostic delay (from 1.4 to 4.9 years p = 0.002), which in separated analyses was statistically significant only for girls from 1.8 to 4.9 years (p = 0.018). In Cox regression male sex was associated with decreased diagnostic delay (p = 0.023) while positive MDD screening with prolonged diagnostic delay (p = 0.015).Conclusions: The diagnostic delay of ADHD was more than three times longer for girls. Co-occurring symptoms of MDD prolonged diagnostic delay significantly only for girls.","PeriodicalId":19201,"journal":{"name":"Nordic Journal of Psychiatry","volume":" ","pages":"35-41"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145550278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Affective illness onset in women during the pre-, peri-, and post-menopausal phases. 情感性疾病在妇女绝经前、围绝经期和绝经后发病。

IF 1.5 4区医学

Nordic Journal of Psychiatry Pub Date : 2026-01-01 Epub Date: 2025-11-27 DOI: 10.1080/08039488.2025.2589851

Alexia Koukopoulos, Leonardo Tondo, Gabriele Sani, Delfina Janiri, Lavinia De Chiara, Ross J Baldessarini

{"title":"Affective illness onset in women during the pre-, peri-, and post-menopausal phases.","authors":"Alexia Koukopoulos, Leonardo Tondo, Gabriele Sani, Delfina Janiri, Lavinia De Chiara, Ross J Baldessarini","doi":"10.1080/08039488.2025.2589851","DOIUrl":"10.1080/08039488.2025.2589851","url":null,"abstract":"Background: Many reports associate particular phases of the human reproductive cycle with psychiatric symptoms including depression, although details of associations of morbidity of depressive, bipolar, and anxiety disorders with pre-, peri-, and post-menopausal phases require further clarification. This naturalistic study evaluated the timing of onset and morbidity of mood and anxiety disorders in women during these menopausal phases.Methods: Women (N = 928) with a primary diagnosis of BD type I or II (BD1 or BD2), major depressive disorder (MDD) or an anxiety disorder were clinically evaluated after menopause to determine the onset of affective illness during the pre, peri-, or post-menopausal phases. Psychometric scales were used to assess affective illness and multivariable regression modeling was used to compare menopausal phases.Results: Many descriptive and clinical measures differed significantly with illnesses starting in the three menstrual phases. Women with onset of affective illness in the perimenopause phase spent 1.33 more time ill than those starting in the premenopausal phase and 1.46 more time ill than women with postmenopausal onset, with corresponding differences in illness episodes/year as well as suicidal risks.Conclusions: Study findings are consistent with the view that onset in the peri-menopausal phase may be associated with an excess of affective morbidity in both MDD and BD and that the post-menopausal phase may involve less morbidity.","PeriodicalId":19201,"journal":{"name":"Nordic Journal of Psychiatry","volume":" ","pages":"59-65"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145636717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0