Nutrition & Metabolism最新文献

{"title":"Association of pericardial fat volume with risk of incident type 2 diabetes mellitus or major adverse cardiovascular events: Evidence from UK Biobank cohort study.","authors":"Feng Hu, Jing Wang, Xinjie Zeng, Hui Chen, Chaoyang Lin, Fayuan Fu, Lin Fan","doi":"10.1186/s12986-026-01127-y","DOIUrl":"https://doi.org/10.1186/s12986-026-01127-y","url":null,"abstract":"<p><strong>Background: </strong>This study seeks to investigate the relationship between pericardial fat volume and the risk of developing type 2 diabetes mellitus (T2DM) and major adverse cardiovascular events (MACE).</p><p><strong>Methods: </strong>The analysis included a cohort of 39, 125 participants from the UK Biobank. The associations between the mean estimate pericardial fat area (MEPFA), as measured by cardiac magnetic resonance imaging, and the incidence of T2DM and MACE were evaluated using multivariable Cox proportional hazards regression models and Kaplan-Meier survival curves.</p><p><strong>Results: </strong>There were 343 occurrences of new-onset T2DM and 1, 894 occurrences of new-onset MACE over a median follow-up period of 55 months. Compared with patients with MEPFA ≤ 13.80 cm², there was a significantly higher risk of new-onset T2DM (adjusted-HR: 2.09, 95% CI 1.38 to 3.18, P < 0.001) and MACE (adjusted-HR: 1.19, 95% CI 1.02 to 1.39, P = 0.027) in the highest MEPFA quartiles. The survival analysis further substantiated this discrepancy, with a log-rank test yielding P < 0.001. Participants exhibiting higher levels of MEPFA demonstrated poorer left ventricular morphology, systolic function, and global strain.</p><p><strong>Conclusions: </strong>The findings indicated that elevated MEPFA levels were significantly and independently associated with the onset of T2DM and MACE. Preliminary results suggested that increased levels of pericardial fat might enhance the predictive capability for cardio-metabolic risk.</p>","PeriodicalId":19196,"journal":{"name":"Nutrition & Metabolism","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147856501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthy diet scores and ultra-processed foods with incident coronary heart disease: a prospective study.","authors":"Mahdieh Golzarand, Ali Nikparast, Golnaz Khodayari, Nastaran Vakilbashi, Parvin Mirmiran, Fereidoun Azizi","doi":"10.1186/s12986-026-01134-z","DOIUrl":"https://doi.org/10.1186/s12986-026-01134-z","url":null,"abstract":"<p><strong>Background: </strong>The extent to which adherence to healthy dietary patterns impacts the association between ultra-processed food (UPF) intake and coronary heart disease (CHD) remains uncertain, particularly in Middle Eastern populations undergoing rapid nutritional transitions. We examined the independent and joint associations of several healthy diet scores and UPF consumption with incident CHD in Iranian adults.</p><p><strong>Methods: </strong>We analyzed 2,921 men and women from the Tehran Lipid and Glucose Study who were free of cardiovascular disease at baseline. Diet was assessed using a food-frequency questionnaire, and the Mediterranean diet (MeDi), Dietary Approaches to Stop Hypertension (DASH), the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND), and the healthful Plant-based Diet Index (hPDI) scores were calculated. UPF intake was also calculated. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>Over a median follow-up of 10.6 years, higher UPF intake was associated with increased CHD risk (HR: 1.57; 95% CI: 1.02-2.43); in contrast, higher MeDi, DASH, and MIND scores were inversely associated with CHD. The associations for the hPDI were weaker. Joint analyses revealed that participants with low UPF consumption in combination with healthy diet scores had a significantly reduced risk of CHD. The hazard ratios were 0.47 (95% CI: 0.29-0.75) for the MeDi, 0.56 (95% CI: 0.37-0.85) for the DASH, 0.59 (95% CI: 0.38-0.90) for the MIND, and 0.59 (95% CI: 0.38-0.93) for the hPDI scores. Furthermore, high MeDi (HR: 0.50; 95% CI: 0.31-0.83) and high DASH (HR: 0.58; 95% CI: 0.36-0.92) scores were associated with a lower CHD risk even among participants with high UPF intake.</p><p><strong>Conclusion: </strong>In this Iranian cohort, MeDi, DASH, and MIND were more informative than hPDI for CHD risk. The favorable CHD risk profile was shown in participants with high adherence to the MeDi and DASH scores combined with either low or high UPF intake. Adherence to the MIND and hPDI scores is effective only in those with low UPF consumption.</p>","PeriodicalId":19196,"journal":{"name":"Nutrition & Metabolism","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147840863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the perfect workout: exercise modalities and dosages to combat visceral adipose tissue in individuals with overweight and obesity - a systematic review with pairwise, network, and dose-response meta-analyses.","authors":"Yuanbo Chang, Lu Wang, Hai Wang, Enyan Zhan","doi":"10.1186/s12986-026-01129-w","DOIUrl":"https://doi.org/10.1186/s12986-026-01129-w","url":null,"abstract":"<p><strong>Background: </strong>Visceral adipose tissue (VAT) plays a crucial role in obesity-related metabolic diseases, making its reduction an important target for obesity treatment. Although exercise has been shown to significantly reduce visceral fat, the specific mechanisms underlying the effects of different exercise modalities and exercise doses on VAT reduction remain unclear, particularly regarding the dose-response relationship, which has not been systematically explored.</p><p><strong>Objective: </strong>This study aims to systematically compare the effects of different exercise modalities on visceral adipose tissue (VAT) reduction and to explore in depth the dose-response relationship between exercise dose and VAT decrease, thereby providing scientific evidence for optimizing individualized exercise prescriptions in obesity treatment.</p><p><strong>Methods: </strong>A systematic search of randomized controlled trials (RCTs) up to November 2024 was conducted (search updated in September 2025). Network meta-analysis (NMA) was employed to compare the effects of different exercise interventions on VAT, while Bayesian network meta-analysis (MBNMA) was used for dose-response analysis to evaluate the impact of exercise intensity, frequency, and duration on VAT reduction.</p><p><strong>Results: </strong>This study included 61 RCTs involving 4,136 participants. The NMA results indicated that all exercise interventions significantly reduced VAT compared to the control group. Among them, HIIT was the most effective in reducing VAT (SMD = -0.84, 95% CI [-1.08, -0.61], p < 0.0001, GRADE: Moderate; SUCRA = 99.3%, GRADE: High), followed by AE + RT (SMD = -0.54, 95% CI [-0.75, -0.32], p < 0.0001, GRADE: Moderate; SUCRA = 59.1%, GRADE: High), AE (SMD = -0.53, 95% CI [-0.68, -0.38], p < 0.001, GRADE: Low; SUCRA = 58.9%, GRADE: High), and RT (SMD = -0.41, 95% CI [-0.63, -0.20], p < 0.001, GRADE: Moderate; SUCRA = 32.7%, GRADE: High). The dose-response analysis showed a significant nonlinear dose-response relationship between total exercise volume and VAT, with the minimum effective dose being 730 METs min/week. Furthermore, the minimum effective doses for different exercise types varied. Specifically, HIIT significantly reduced VAT at a lower dose (400 METs min/week), while AE and AE + RT required a higher dose (1100 METs min/week) for significant reduction.</p><p><strong>Conclusion: </strong>This study reveals a nonlinear dose-response relationship between exercise dose and VAT reduction, demonstrating that HIIT is the most effective exercise modality for reducing VAT, with significant effects at low doses. AE and AE + RT are also effective but require higher doses (1100 METs min/week) to achieve significant VAT reduction. These findings provide specific dosage recommendations for exercise prescriptions for individuals with obesity, helping to optimize treatment plans and improve obesity management outcomes.</p>","PeriodicalId":19196,"journal":{"name":"Nutrition & Metabolism","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147840858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher salivary nitrite is associated with improved glycemic control and insulin sensitivity in patients with type 2 diabetes.","authors":"Zahra Bahadoran, Reza Norouzirad, Sajad Jeddi, Asghar Ghasemi","doi":"10.1186/s12986-026-01104-5","DOIUrl":"https://doi.org/10.1186/s12986-026-01104-5","url":null,"abstract":"<p><strong>Background and aim: </strong>Salivary nitrite (SNO₂), a marker of oral nitrate-reducing capacity and nitric oxide (NO) bioavailability, often impaired in type 2 diabetes (T2DM). This study aimed to investigate the associations between SNO₂ concentration, and metabolic, vascular, and renal parameters in patients with T2DM.</p><p><strong>Methods: </strong>Sixty-four adults with T2DM (53.9 ± 7.2 years, 45.3% men, diabetes duration 8.3 ± 6.2 years) participated in this cross-sectional study. Salivary NO₂ concentrations, glycemic parameters, blood pressure (BP) indices, renal function, lipid profiles, liver function, and systemic NO metabolites were measured. Participants with high- and low-SNO₂ (< and ≥ 69.3 µmol/L) were compared for cardiometabolic parameters.</p><p><strong>Results: </strong>Compared with the low-SNO₂ group, participants with higher SNO₂ had lower HbA1c (6.2% vs. 6.9%, P = 0.040), fasting insulin (6.1 vs. 8.2 µU/mL, P = 0.007), HOMA-IR (2.1 vs. 3.3, P = 0.003), and C-peptide (1.3 vs. 1.7 ng/mL, P = 0.023), with higher QUICKI (0.34 vs. 0.32, P = 0.003). Fasting serum glucose was marginally lower (142 vs. 167 mg/dL, P = 0.069) in the high- compared to the low-SNO₂ group. Median serum nitric oxide metabolites (NOx) concentrations were higher in the high-SNO₂ group (51.1 vs. 29.1 µmol/L, P = 0.015). Salivary nitrate (NO₃) (694 vs. 463 µmol/L, P = 0.035) and NO₂ (153 vs. 20.6, P = 0.001) were also higher in the high- compared to low-SNO₂ group. No significant difference was observed in BP measures, lipid profile, and liver and renal function test across groups.</p><p><strong>Conclusions: </strong>High-SNO₂ levels were associated with greater glycemic control, insulin sensitivity, and NO bioavailability in patients with T2DM.</p>","PeriodicalId":19196,"journal":{"name":"Nutrition & Metabolism","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147840883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of regular consumption of a β-glucan-rich oyster mushroom powder on cholesterol metabolism in adults with moderately elevated LDL-cholesterol concentrations: a double-blind randomized controlled trial.","authors":"Jana Johnen, Julia Waizenegger, Jörg Ellinger, Dieter Lütjohann, Kristina E Steffens, Karl G Wagner, Birgit Stoffel-Wagner, Ramona Dolscheid-Pommerich, Sabine Ellinger","doi":"10.1186/s12986-026-01122-3","DOIUrl":"10.1186/s12986-026-01122-3","url":null,"abstract":"<p><strong>Background: </strong>Oyster mushrooms (Pleurotus ostreatus, PO) are rich in β-glucans and other ingredients with cholesterol-lowering potential. While human intervention studies suggest that PO intake may reduce total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and triglycerides, current evidence remains limited due to methodological limitations of the studies. Thus, this study investigated whether regular intake of PO powder affects LDL-C concentrations in adults with moderately elevated LDL-C (primary aim). Moreover, the study explored the effect on other lipids (TC, high-density lipoprotein cholesterol, triglycerides), on apolipoproteins A1 and B and possible underlying mechanisms of action (secondary aims).</p><p><strong>Methods: </strong>In a double-blind, randomized controlled trial, 46 adults (37 female, 9 male) with moderately elevated LDL-C (116-190 mg/dL) consumed a beverage containing 8.4 g PO powder providing 3 g of β-glucans or a beverage without PO daily over 4 weeks. Plasma concentrations of LDL-C, other lipids and apolipoproteins were measured before and after intervention. The concentrations of noncholesterol sterols in serum, normalized to cholesterol, were determined as validated surrogate markers for cholesterol absorption (sitosterol, campesterol, and 5α-cholestanol), cholesterol synthesis (lathosterol), and bile-acid synthesis (7α-hydroxycholesterol), along with ergosterol, a fungal-specific sterol. Expression of selected target genes involved in cholesterol metabolism was analyzed in blood. Statistical analysis included comparisons of the changes between the groups (treatment effect) and linear modeling.</p><p><strong>Results: </strong>PO treatment did not modulate LDL-C; no treatment effect was observed for other lipids, apolipoproteins or gene expression (P ≥ 0.05 for all). However, after adjustment for sex, linear model analysis showed a reduction in markers of cholesterol absorption, especially in females (P < 0.05 for all). No effects were observed on markers of cholesterol and bile-acid synthesis (P ≥ 0.05 for all). Ergosterol was detectable in all serum samples after PO intake, confirming high compliance with PO treatment.</p><p><strong>Conclusions: </strong>Daily consumption of 8.4 g of PO powder over 4 weeks has no impact on LDL-C concentrations in adults with moderately elevated LDL-C concentrations. However, post-hoc analysis indicates a sex-dependent reduction in cholesterol absorption by PO consumption, especially in females, suggesting that PO may have the potential to beneficially modulate cholesterol metabolism.</p><p><strong>Trial registration: </strong>Registration at German Clinical Trials Register; DRKS-ID: DRKS00033943; registration date: 21/03/2024. https://drks.de/search/de/trial/DRKS00033943 .</p>","PeriodicalId":19196,"journal":{"name":"Nutrition & Metabolism","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13147704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147818223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary index for gut microbiota and risk of hypertension: the mediating role of HOMA-IR in a five-year prospective cohort study in Iranian adults.","authors":"Ali Nikparast, Mohsen Maleki, Nazanin Zamanian, Leila Sheikhi, Elahe Etesami, Gholamali Javdan, Reza Homayounfar, Jalaledin Mirzay Razaz","doi":"10.1186/s12986-026-01121-4","DOIUrl":"https://doi.org/10.1186/s12986-026-01121-4","url":null,"abstract":"<p><strong>Background: </strong>Diet-microbiota interactions may influence blood pressure via metabolic pathways, but prospective evidence on microbiota-supportive dietary patterns and incident hypertension, particularly in Middle Eastern populations, is limited. We examined the association between a Dietary Index for Gut Microbiota (DI-GM) and incident hypertension, and assessed whether insulin resistance, measured by homeostatic model assessment for insulin resistance (HOMA-IR), mediates this relationship.</p><p><strong>Methods: </strong>This prospective cohort included 5,185 Iranian adults free of hypertension at baseline. Usual dietary intake was assessed using a validated 125-item food-frequency questionnaire, and a 12-component DI-GM was computed. Incident hypertension over five years was defined according to JNC-7 criteria. Multivariable logistic regression estimated odds ratios (ORs) and 95% confidence intervals (CIs) for hypertension across DI-GM quartiles and per one-unit increment. Mediation by HOMA-IR was evaluated using bootstrapped mediation analysis with 10,000 resamples.</p><p><strong>Results: </strong>During follow-up, 2,150 participants experienced incident hypertension (41.5%). In fully adjusted models, participants in the highest DI-GM quartile had 21% lower odds of hypertension than those in the lowest quartile (OR 0.79, 95% CI 0.66-0.95), and each one-unit higher DI-GM was associated with 4% lower odds (OR 0.96, 95% CI 0.93-0.99). Results were robust in multiple sensitivity analyses. Approximately 34.5% of the association between DI-GM and hypertension was mediated by HOMA-IR.</p><p><strong>Conclusions: </strong>A microbiota-supportive dietary pattern is prospectively associated with a lower risk of incident hypertension, and about one-third of this relationship appears to operate through reduced insulin resistance. These findings support the promotion of gut-friendly dietary patterns in strategies for hypertension prevention.</p>","PeriodicalId":19196,"journal":{"name":"Nutrition & Metabolism","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147818306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"B vitamins and cardiovascular health: mechanisms, clinical evidence, and precision prevention strategies.","authors":"Ameer Awashra, Mohammed AbuBaha, Kareem Istetieh, Dana Sandouka, Samia Aldwaik, Bara AbuBaha, Sarah Saife, Ahmed Emara, Anwar Zahran, Mohamed S Elgendy, Abdalhakim Shubietah, Muath A Baniowda","doi":"10.1186/s12986-026-01125-0","DOIUrl":"https://doi.org/10.1186/s12986-026-01125-0","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular diseases is the most common cause of mortality in the world. B vitamins (B₁-B₁₂) control how mitochondria make energy, how nitric oxide is made, how one-carbon is used, and how genes work. A deficiency leads to hyperhomocysteinemia, oxidative stress, and endothelial dysfunction, all of which are important to vascular disease. Observational studies consistently associate low B-vitamin levels with an elevated risk of cardiovascular diseases; nevertheless, randomized supplementation trials have demonstrated only modest reductions in significant events.</p><p><strong>Methods: </strong>This narrative review summarizes molecular, epidemiological, and clinical evidence on the role of B vitamins in cardiovascular health. Special focus was paid to functional biomarkers and gene-nutrient interactions that affect how well a therapy works. The literature was identified through targeted searches of PubMed, Scopus, and Google Scholar. Priority was given to high-quality evidence, including mechanistic studies, observational cohorts, randomized controlled trials, meta-analyses, and major review articles relevant to cardiovascular outcomes.</p><p><strong>Results: </strong>Functional indicators, such as methylmalonic acid and holotranscobalamin, offer superior accuracy compared to blood levels in assessing vitamin status. Nutrigenetic interactions, particularly the effects of folate and riboflavin on methylenetetrahydrofolate reductase polymorphisms, exhibit blood pressure-lowering and stroke-preventive advantages. The clinical efficacy of B-vitamin supplementation is highly dependent on baseline nutritional status and regional food fortification policies. For example, folic acid supplementation significantly reduces stroke incidence in populations who lack mandatory folate fortification, whereas trials conducted in folate-sufficient cohorts generally demonstrated no added cardiovascular benefit. Recognizing this population-specific variability helps explain the historical discrepancy between the strong mechanistic potential of B-vitamins and the mixed results observed in large-scale clinical trials.</p><p><strong>Conclusion: </strong>While adequate B-vitamin status remains mechanistically essential for cardiovascular homeostasis, the clinical benefits of routine supplementation are nuanced and highly population-dependent. Consequently, ubiquitous supplementation is unlikely to produce extensive advantages. A precision strategy that combines biomarkers, genotype stratification, and population context can help find their therapeutic potential. Future methods should integrate diet with precision cardiology to enhance vascular prevention.</p>","PeriodicalId":19196,"journal":{"name":"Nutrition & Metabolism","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147818295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between low phase angle and impaired healing of diabetic foot ulcer: a retrospective cohort study.","authors":"Zhimin Yuan, Guojuan Lao, Jiande Liu, Ying Jian, Jianmin Ran, Chaogang Chen, Ping Zhu","doi":"10.1186/s12986-026-01126-z","DOIUrl":"https://doi.org/10.1186/s12986-026-01126-z","url":null,"abstract":"","PeriodicalId":19196,"journal":{"name":"Nutrition & Metabolism","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender-specific associations of diet quality and dietary patterns with metabolic syndrome: evidence from Korea National Health and Nutrition Examination Survey (KNHANES) VI.","authors":"Haeng Jeon Hur, Hye Jeong Yang, Min Jung Kim, Hyun-Jun Jang, Byung-Kook Lee, Myung-Sunny Kim, Sunmin Park","doi":"10.1186/s12986-026-01116-1","DOIUrl":"https://doi.org/10.1186/s12986-026-01116-1","url":null,"abstract":"","PeriodicalId":19196,"journal":{"name":"Nutrition & Metabolism","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiometabolic health and all-cause and cause-specific mortality in the general US adult population.","authors":"Chuxian Guo, Xiaomei Hu, Shaojie Han, Bin Li, Huimin Zhu, Panpan Li, Lei Xu, Zenghui Zhang, Jun Guo","doi":"10.1186/s12986-026-01085-5","DOIUrl":"https://doi.org/10.1186/s12986-026-01085-5","url":null,"abstract":"","PeriodicalId":19196,"journal":{"name":"Nutrition & Metabolism","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}