Journal of Natural Sciences and Mathematics Research最新文献

{"title":"Bioactivity mapping of secondary metabolite compounds of Pandanus amaryllifolius leaves as anti-inflammatory using in silico","authors":"Robiatush Sholichah Arrohmah, Afina Anjani Ibtisam, Siti Malihatus Sa’adah, Fensy Rania Putri, Fitriyah Fitriyah","doi":"10.21580/jnsmr.2023.9.1.16215","DOIUrl":"https://doi.org/10.21580/jnsmr.2023.9.1.16215","url":null,"abstract":"Inflammation is one of the primary responses of the immune system to infection and irritation. Anti-inflammatory drugs generally cause side effects. Anti-inflammatory developed by reducing side effects use many natural materials such as plants. The parts of the plant used include fruits, leaves, stem bark, rhizomes, and flowers. One of the plants that can be used as an anti-inflammatory is Pandanus amaryllifolius. P. amaryllifolius leaves contain several materials, such as flavonoids, alkaloids, saponins, tannins, polyphenols, and dyes. This study aimed to determine the anti-inflammatory potential of the secondary metabolites of Pandanus amaryllifolius leaves using the in silico method. The research used a descriptive exploratory method and was conducted from December 2022 – January 2023. In silico mapping of the bioactivity of active compounds was carried out using several software or websites: knapsack database (www.knapsackfamily.com), NCBI PubChem database (https://pubchem.ncbi.nlm.nih.gov/), PASS Online Way 2 Drug (http://www.way2drug.com/passonline/) and ADME Swiss Analysis (http://www.swissadme.ch/). The result shows P. amarylifolius has 31 active compounds. The compounds were then analyzed using Pass Online with 18 anti-inflammatory parameters. It explained that 3 compounds met the rules for Pa values 0.7, namely compounds 6E-Pandanamine (0.758), Pandamenyamine (0.735), and Pandamarilactone 1 (0.709). The results of pharmacokinetic tests using Lipinski","PeriodicalId":191192,"journal":{"name":"Journal of Natural Sciences and Mathematics Research","volume":"55 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139181797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical analysis of secondary metabolite compounds of Pandanwangi leaf extract (Pandanus amaryllifolius)","authors":"Siti Malihatus Sa’adah, Fensy Rania Putri, Afina Anjani Ibtisam, Robiatush Sholichah Arrohmah, Fitriyah Fitriyah","doi":"10.21580/jnsmr.2023.9.2.16421","DOIUrl":"https://doi.org/10.21580/jnsmr.2023.9.2.16421","url":null,"abstract":"The majority of people use pandan as a dye, food fragrance, and natural medicine because it contains secondary metabolites such as alkaloids, saponins, and phenolics. Therefore, this research aims to explore the secondary metabolites of Pandanus amaryllifolius using qualitative and quantitative methods. The research begins by taking samples of pandan leaves, which are then extracted and tested qualitatively and quantitatively. The qualitative test results showed that pandan leaf extract contained flavonoids, polyphenols, and tannins. In the quantitative test of pandan leaf phenolic compounds using a UV-Vis spectrometer with gallic acid concentrations of 80 ppm, 100 ppm, 120 ppm, and 140 ppm, Based on the quantitative test, the total phenolic content of pandan extract is 114 mg/L.","PeriodicalId":191192,"journal":{"name":"Journal of Natural Sciences and Mathematics Research","volume":"9 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139180699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Industrial wastewater treatment using venture injector type Micro-bubble aeration as a reduction of dissolved Iron (Fe2+) levels","authors":"Dimas Amirul Mukminin Nur Efendi, Adityas Agung Ramandani, Děvy Cendekia, Windia Hanifah","doi":"10.21580/jnsmr.2023.9.2.17594","DOIUrl":"https://doi.org/10.21580/jnsmr.2023.9.2.17594","url":null,"abstract":"Water quality problems that are often encountered, especially by-product wastewater resulting from industrial processes that do not meet the requirements for wastewater quality standards. Iron levels in wastewater can cause the water to turn brownish yellow and produce an unpleasant odor, which of course has a big impact on the environment. Therefore, it is necessary to implement a treatment process to reduce the iron level in the water, ensuring that the water is safe when discharged into the environment. The purpose of this research is to analyze the initial parameters of temperature, pH, TDS, TSS, dissolved oxygen (DO) and dissolved iron (Fe2+) in industrial waste water and then wanted to know whether the venture injector type micro bubble aeration process was able to increase the value of dissolved oxygen (DO) and decrease the dissolved iron content (Fe2+) in wastewater and to know the micro bubble type aeration process Venture injectors are the best to use. The research was conducted with an experimental design using a completely randomized design (RAL) with two factors: air flow (2 LPM, 4 LPM, and 6 LPM) and aeration time (0 minutes, 15 minutes, 30 minutes, 45 minutes, and 60 minutes), each with two repetitions. In the results of the initial parameter analysis, the pH value was 8.02 (alkaline), the temperature value was 28°C, the TDS value was 1548.3 mg/L, the TSS value was 291 mg/L, the DO value was 0.1 mg/L and dissolved iron (Fe2+) of 7.453 mg/L. After conducting research, it was found that the venture injector type micro bubble aeration process was able to increase the value of dissolved oxygen (DO) and reduce dissolved iron (Fe2+) in industrial waste water, the best increase in dissolved oxygen (DO) at 6 LPM air flow for 60 minutes was able to increase oxygen dissolved (DO) to 2.40 mg/L. The most efficient and effective reduction in the value of dissolved iron (Fe2+) at 6 LPM air flow with a time of 15 minutes was able to reduce the value of dissolved iron by 84.42%.","PeriodicalId":191192,"journal":{"name":"Journal of Natural Sciences and Mathematics Research","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139181288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formulation and analysis of physical properties of Turi leaf extract suspension (Sesbania grandiflora L.)","authors":"Wilda Amananti, ‪Rosaria Ika Pratiwi‬","doi":"10.21580/jnsmr.2023.9.1.13901","DOIUrl":"https://doi.org/10.21580/jnsmr.2023.9.1.13901","url":null,"abstract":"Sesbania Grandiflora .L is a type of plant that has so many benefits in the treatment of various kinds Diseases include laxatives, pain relievers (analgesics), fever reducers (antipyretic), laxative urine (diuretic), and others. Almost all parts of This plant belonging to the genus Sesbania Grandiflora is efficacious as a medicine covering the skin stems, flowers, leaves and roots. Sesbania Grandiflora .L  contains alkaloid compounds, glycosides, flavonoids, saponins, tannins and phenols which give a positive reaction in the phytochemical screening assay. Turi leaf extract need to be made in the form of pharmaceutical dosage forms for ease of use. One preparation that can be applied is a suspension.In this study, turi leaf extract was used as the active substance. The suspension was made in 3 formulas with different concentrations of turi leaf extract. The finished suspension was tested for physical characteristics including organoleptic test, homogeneity test, pH test, density test and viscosity test.Based on the results of secondary metabolite tests, turi leaves contain alkaloids, flavonoids, tannins and saponins. Based on the results of testing the physical properties of the suspension, it showed that all formulas met SNI standards based on organoleptic, homogeneity, pH and density tests. while based on the viscosity test the suspension made does not meet SNI standards.","PeriodicalId":191192,"journal":{"name":"Journal of Natural Sciences and Mathematics Research","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129919439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scalar fields as dark matter candidates in the modified left-right symmetry model","authors":"I. Istikomah, N. Isnawati","doi":"10.21580/jnsmr.2023.9.1.17481","DOIUrl":"https://doi.org/10.21580/jnsmr.2023.9.1.17481","url":null,"abstract":"Dark matter is about 25% of the universe, but its existence is still a mystery. The Modified Left-Right Symmetry Model with the extension of the scalar field, is expected to explain dark matter candidate. The dark matter candidates were analyzed using the Higgs Potential and Lagrangian Yukawa to obtain information on decay and scattering interactions. The generation of dark matter can be determined by analyzing the temperature evolution of the universe, which is divided into three stages post-inflation reheating, symmetry breaking first step, and symmetry breaking second step. The analysis results show that the right-sector scalar field  can be Cold Dark Matter (CDM) candidate because it has non-relativistic characteristics, is stable, does not interact with fermions, and has an abundance of 0.004. The right-sector atom can also be a CDM candidate because it has non-relativistic characteristics, is neutral, and consists of the right nucleons and right electrons. The singlet scalar field  can be the Warm Dark Matter (WDM) candidate because it can decay into fermion, interact in the left and right sectors, is neutrally charged and does not interact with other particles electromagnetically and has an abundance of 0.003. Thus, based on the modified left-right symmetry model, the particle that can be a candidate for dark matter is the scalar field.","PeriodicalId":191192,"journal":{"name":"Journal of Natural Sciences and Mathematics Research","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125558620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precipitated calcium oxide nanosize from limestone and blood clam shells","authors":"C. Pujiastuti, Srie Muljani, K. Sumada","doi":"10.21580/jnsmr.2023.9.1.13209","DOIUrl":"https://doi.org/10.21580/jnsmr.2023.9.1.13209","url":null,"abstract":"Calcium oxide (CaO) is a product that is needed by various types of industries such as the pharmaceutical, chemical, agricultural and health industries. CaO is generally produced by the calcination method of CaCO3 materials such as calcium carbonate rocks or from various types of shells. The calcination method requires a large amount of energy because the operating temperature is above 1000 C and the resulting calcium oxide product is still micrometer size. This study developed nanosize precipitated CaO from two calcium sources, namely blood clam shells and limestone. For clam shells using hydrochloric acid as a solvent and sodium hydroxide as a precipitating agent, while for limestone using phosphoric acid as a solvent and potassium hydroxide as a precipitating agent. The effect of acidity (pH) and calcination temperature on the characteristics of the precipitated CaO was observed. The blood calm shell produces precipitated CaO 85-92 % with a particle size of 200-250 Nm and the limestone produces precipitated CaO 42-66% with a particle size of 250-300 Nm ","PeriodicalId":191192,"journal":{"name":"Journal of Natural Sciences and Mathematics Research","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127810696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioplastic from Cassava peel and eggshell waste","authors":"Nila Tanyela Berghuis, Diah Kemala Mutmainah, Meliana Nur Savitri, Meri Arizki, Dyas Dwi Yunita, Fahdly Awaluddin, Rehan Rizkyta Peranginangin, Athirah Nursalsabila, Ris Kevin Bramasta","doi":"10.21580/jnsmr.2022.8.2.13696","DOIUrl":"https://doi.org/10.21580/jnsmr.2022.8.2.13696","url":null,"abstract":"The accumulation of plastic waste and excessive use of plastic is a common environmental issue in Indonesia. Plastics are synthetic polymers that are stable, water-resistant, light, flexible, and firm but very difficult to break down by microorganisms. Decomposition of plastic waste by burning can cause other environmental issues and, during the combustion process can produce dioxin compounds that are harmful to health. An available and affordable alternative to reduce the use of plastic is by using bioplastics. Bioplastics are plastics made from natural materials that microorganisms can break down, so they are more environmentally friendly than commercial plastics. Generally, the main ingredients for making bioplastics are starch or chitosan. The source of starch used in this project comes from cassava peel waste. In this project, researchers also utilize waste from chicken eggshells. The function of adding eggshell waste is to give biodegradable plastic complex characteristics. The ratio between cassava peel and eggshell used was 1:0, 1:1, 1:3, and 1:5. With a 1:1 ratio is the most optimal. The addition of eggshells with the correct ratio (1:1) increased the ability of biodegradation of bioplastics. The results of the Tensile Strength Test of Bioplastic Samples with a ratio of 1:0, 1:1, 1:3, and 1:5 are 9.2 x10-3kgf/cm2, 4.4 x10-3 kgf/cm2, 2 x10-3 kgf/cm2, and 2 x10-3 kgf/cm2.©2022 JNSMR UIN Walisongo. All rights reserved.","PeriodicalId":191192,"journal":{"name":"Journal of Natural Sciences and Mathematics Research","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128436641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fermion mass formulation in the Modified Left-Right Symmetry Model","authors":"N. Isnawati, I. Istikomah, Muhammad Ardhi Khalif","doi":"10.21580/jnsmr.2022.8.2.13633","DOIUrl":"https://doi.org/10.21580/jnsmr.2022.8.2.13633","url":null,"abstract":"The Modified Left Right Symmetry Model is an extension of the Standard Model. This model introduces left-handed neutrinos to the right sector and a doublet scalar field to the left sector. This model cannot yet explain the mass generation of fermions and neutrinos. This study is theoretical research using the literature review method. Generating the masses of fermions (quark up-down) and electrons through spontaneous symmetry breaking in Yukawa's Lagrangian term produces a particle mass in the left sector, the same as the calculations in the Standard Model. The masses of fermions (up-down quarks) and electrons for the right sector produced in this study are much more massive than those of fermions (up-down quarks) and the left sector. The neutrino masses produced in this study are by following the Seesaw Mechanism. That is, if one neutrino mass is massive, then the other neutrino masses will be light.©2022 JNSMR UIN Walisongo. All rights reserved.","PeriodicalId":191192,"journal":{"name":"Journal of Natural Sciences and Mathematics Research","volume":"293 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132279768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Second kind Chebyshev collocation technique for Volterra-Fredholm fractional order integro-differential equations","authors":"T. Oyedepo, A. A. Ayoade, I. Otaide, A. Ayinde","doi":"10.21580/jnsmr.2022.8.2.13021","DOIUrl":"https://doi.org/10.21580/jnsmr.2022.8.2.13021","url":null,"abstract":"In this work, we present the numerical solution of fractional order Volterra–Fredholm integro-differential equations using the second kind of Chebyshev collocation technique. First, we transformed the problem into a system of linear algebraic equations, which are then solved using matrix inversion to obtain the unknown constants. Furthermore, numerical examples are used to outline the method’s accuracy and efficiency using tables and figures. The results show that the method performed better in terms of improving accuracy and requiring less rigorous work.©2022 JNSMR UIN Walisongo. All rights reserved.","PeriodicalId":191192,"journal":{"name":"Journal of Natural Sciences and Mathematics Research","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128992352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of alteration zone and gold mineralization based on magnetic anomaly and 3D model of geomagnetic satellite data inversion of Mount Pongkor Area, West Java","authors":"N. R. Permana, B. Gunawan, A. A. Primastika, Dias Shafa, Dhika Faiz Fadrian, Fardhan Rafshan Zani","doi":"10.21580/jnsmr.2022.8.2.13177","DOIUrl":"https://doi.org/10.21580/jnsmr.2022.8.2.13177","url":null,"abstract":"Mount Pongkor is one of the areas in Indonesia with the largest gold mineralization potential in Java. One of the geophysical methods to identify the distribution of gold mineralization zones is the geomagnetic method that utilizes magnetic properties in the subsurface due to the influence of rock magnetization. Geomagnetic research has been conducted at Mount Pongkor, Bogor Regency, West Java with an area of 22 x 17 km as much as 793 magnetic satellite data from the National Oceanic and Atmospheric Administration (NOAA) website that has been corrected daily. This study aims to determine the distribution of alteration zones and mineralization of the study area. The results showed that the RTP map shows the distribution of magnetic anomalies ranging from -4.786 – 4.663 nT, with high anomalies in the north-south direction associated with mineralization zones with anomaly values ranging from 1.881 – 4.663 nT and low anomalies in the north-south direction associated with rock alteration zones with anomaly values ranging from -4,786 - (-2.174) nT.  In the 3D inversion model, the alteration zone has an average depth of 350 - 2600 m from topography with susceptibility contrast values ranging from -0.35 - (- 0.25) SI and the mineralization zone has an average depth of 350 - 2800 m from topography with susceptibility contrast values of 0.25 - 0.35 SI.©2022 JNSMR UIN Walisongo. All rights reserved.","PeriodicalId":191192,"journal":{"name":"Journal of Natural Sciences and Mathematics Research","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127817498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}