发布求助
文献互助 智能选刊 最新文献

Nature Reviews. Drug Discovery最新文献

筛选
英文 中文
Pulsatile FXR agonism 脉动性FXR激动作用。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-29 DOI: 10.1038/d41573-026-00108-3
Sarah Crunkhorn
{"title":"Pulsatile FXR agonism","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-026-00108-3","DOIUrl":"10.1038/d41573-026-00108-3","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 8","pages":"594-594"},"PeriodicalIF":91.2,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148352698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Designing GPCR-targeted miniproteins 设计gpcr靶向小蛋白。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-29 DOI: 10.1038/d41573-026-00109-2
Sarah Crunkhorn
{"title":"Designing GPCR-targeted miniproteins","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-026-00109-2","DOIUrl":"10.1038/d41573-026-00109-2","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 8","pages":"594-594"},"PeriodicalIF":91.2,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148352762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inflammatory bowel disease-on-a-chip 炎症性肠病-芯片
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-29 DOI: 10.1038/d41573-026-00110-9
Sarah Crunkhorn
{"title":"Inflammatory bowel disease-on-a-chip","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-026-00110-9","DOIUrl":"10.1038/d41573-026-00110-9","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 8","pages":"594-594"},"PeriodicalIF":91.2,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148352684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CRISPR strategy tackles bacterial toxin CRISPR策略处理细菌毒素。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-29 DOI: 10.1038/d41573-026-00112-7
Katie Kingwell
{"title":"CRISPR strategy tackles bacterial toxin","authors":"Katie Kingwell","doi":"10.1038/d41573-026-00112-7","DOIUrl":"10.1038/d41573-026-00112-7","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 8","pages":"593-593"},"PeriodicalIF":91.2,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148352700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
p38α inhibition restores axonal transport P38α抑制恢复轴突运输。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-29 DOI: 10.1038/d41573-026-00111-8
Sarah Crunkhorn
{"title":"p38α inhibition restores axonal transport","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-026-00111-8","DOIUrl":"10.1038/d41573-026-00111-8","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 8","pages":"594-594"},"PeriodicalIF":91.2,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148352746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New antibiotic targets novel ribosomal site 新的抗生素靶向新的核糖体部位。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-18 DOI: 10.1038/d41573-026-00105-6
Sarah Crunkhorn
{"title":"New antibiotic targets novel ribosomal site","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-026-00105-6","DOIUrl":"10.1038/d41573-026-00105-6","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 8","pages":"591-591"},"PeriodicalIF":91.2,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148278209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can multispecific biologics break the efficacy ceiling? 多特异性生物制剂能否打破疗效上限？
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-18 DOI: 10.1038/d41573-026-00106-5
Asher Mullard
{"title":"Can multispecific biologics break the efficacy ceiling?","authors":"Asher Mullard","doi":"10.1038/d41573-026-00106-5","DOIUrl":"10.1038/d41573-026-00106-5","url":null,"abstract":"A growing pipeline of multispecific antibody therapies are in clinical trials, showcasing novel biological effects as well as potential improvements over multi-agent cocktails. A growing pipeline of multispecific antibody therapies are in clinical trials, showcasing novel biological effects as well as potential improvements over multi-agent cocktails.","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 7","pages":"497-500"},"PeriodicalIF":91.2,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148278178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multispecific T-cell engagers attract cancer drug developers 多特异性t细胞接合物吸引癌症药物开发人员。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-18 DOI: 10.1038/d41573-026-00107-4
Asher Mullard
{"title":"Multispecific T-cell engagers attract cancer drug developers","authors":"Asher Mullard","doi":"10.1038/d41573-026-00107-4","DOIUrl":"10.1038/d41573-026-00107-4","url":null,"abstract":"Multispecific T-cell engagers that bind three or more targets on cancer and immune cells promise to address the shortcomings of their bispecific predecessors.","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 8","pages":"579-582"},"PeriodicalIF":91.2,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148278145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Upcoming FDA approval decisions in Q3 2026 FDA将于2026年第三季度做出批准决定。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-12 DOI: 10.1038/d41573-026-00103-8
Swetha Kota
{"title":"Upcoming FDA approval decisions in Q3 2026","authors":"Swetha Kota","doi":"10.1038/d41573-026-00103-8","DOIUrl":"10.1038/d41573-026-00103-8","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 7","pages":"506-506"},"PeriodicalIF":91.2,"publicationDate":"2026-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41573-026-00103-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148239698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The unglamourous AI wins that are quietly transforming drug discovery and development 平淡无奇的人工智能正在悄然改变药物的发现和开发。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-12 DOI: 10.1038/d41573-026-00099-1
Asher Mullard
{"title":"The unglamourous AI wins that are quietly transforming drug discovery and development","authors":"Asher Mullard","doi":"10.1038/d41573-026-00099-1","DOIUrl":"10.1038/d41573-026-00099-1","url":null,"abstract":"David Reese, Amgen’s inaugural Chief Technology Officer, discusses how inconspicuous AI achievements stand to transform drug discovery. David Reese, Amgen’s inaugural Chief Technology Officer, discusses how inconspicuous AI achievements stand to transform drug discovery.","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 7","pages":"507-508"},"PeriodicalIF":91.2,"publicationDate":"2026-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41573-026-00099-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148239686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书