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Nature Reviews. Drug Discovery最新文献

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Embracing the avoid-ome. 拥抱逃避者。
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-10-15 DOI: 10.1038/d41573-025-00169-w
Asher Mullard
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引用次数: 0
FDA new drug approvals in Q3 2025. 2025年第三季度FDA新药批准。
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-10-13 DOI: 10.1038/d41573-025-00170-3
Paul Verdin
{"title":"FDA new drug approvals in Q3 2025.","authors":"Paul Verdin","doi":"10.1038/d41573-025-00170-3","DOIUrl":"https://doi.org/10.1038/d41573-025-00170-3","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":" ","pages":""},"PeriodicalIF":101.8,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Designer peptide retunes channel function. 设计肽恢复通道功能。
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-10-07 DOI: 10.1038/d41573-025-00163-2
Katie Kingwell
{"title":"Designer peptide retunes channel function.","authors":"Katie Kingwell","doi":"10.1038/d41573-025-00163-2","DOIUrl":"https://doi.org/10.1038/d41573-025-00163-2","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":" ","pages":""},"PeriodicalIF":101.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Designing new antibiotics. 设计新的抗生素。
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-23 DOI: 10.1038/d41573-025-00160-5
Sarah Crunkhorn
{"title":"Designing new antibiotics.","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-025-00160-5","DOIUrl":"https://doi.org/10.1038/d41573-025-00160-5","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":" ","pages":""},"PeriodicalIF":101.8,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A degrader of oncoprotein SKP2. 致癌蛋白SKP2的降解物。
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-23 DOI: 10.1038/d41573-025-00159-y
Sarah Crunkhorn
{"title":"A degrader of oncoprotein SKP2.","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-025-00159-y","DOIUrl":"https://doi.org/10.1038/d41573-025-00159-y","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":" ","pages":""},"PeriodicalIF":101.8,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blocking SLC38A2 lowers blood pressure. 阻断SLC38A2可降低血压。
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-23 DOI: 10.1038/d41573-025-00157-0
Sarah Crunkhorn
{"title":"Blocking SLC38A2 lowers blood pressure.","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-025-00157-0","DOIUrl":"https://doi.org/10.1038/d41573-025-00157-0","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":" ","pages":""},"PeriodicalIF":101.8,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Targeting GPR31 to treat MASH. 靶向GPR31治疗MASH。
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-23 DOI: 10.1038/d41573-025-00158-z
Sarah Crunkhorn
{"title":"Targeting GPR31 to treat MASH.","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-025-00158-z","DOIUrl":"https://doi.org/10.1038/d41573-025-00158-z","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":" ","pages":""},"PeriodicalIF":101.8,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Upcoming FDA approval decisions in Q4 2025 FDA将于2025年第四季度做出批准决定
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-15 DOI: 10.1038/d41573-025-00152-5
Kaniaw Dilzer
{"title":"Upcoming FDA approval decisions in Q4 2025","authors":"Kaniaw Dilzer","doi":"10.1038/d41573-025-00152-5","DOIUrl":"10.1038/d41573-025-00152-5","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"735-735"},"PeriodicalIF":101.8,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41573-025-00152-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New US$3.1 billion foundation takes big, long-term bets on bioscience, AI and the environment 新成立的31亿美元基金会对生物科学、人工智能和环境进行了长期的重大投资
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-12 DOI: 10.1038/d41573-025-00154-3
Asher Mullard
{"title":"New US$3.1 billion foundation takes big, long-term bets on bioscience, AI and the environment","authors":"Asher Mullard","doi":"10.1038/d41573-025-00154-3","DOIUrl":"10.1038/d41573-025-00154-3","url":null,"abstract":"Lynda Stuart, president and CEO of the newly launched Fund for Science and Technology, discusses the philanthropic organization’s plans for bioscience and AI. Lynda Stuart, president and CEO of the newly launched Fund for Science and Technology, discusses the philanthropic organization’s plans for bioscience and AI.","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"736-737"},"PeriodicalIF":101.8,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41573-025-00154-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145035705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breakthrough therapy designations in China and the United States 突破性疗法在中国和美国的指定
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-12 DOI: 10.1038/d41573-025-00153-4
Xiangyun Mao,  Yi Li,  Aaron S. Kesselheim,  Yi Ba,  Guanqiao Li
{"title":"Breakthrough therapy designations in China and the United States","authors":"Xiangyun Mao, \u0000 Yi Li, \u0000 Aaron S. Kesselheim, \u0000 Yi Ba, \u0000 Guanqiao Li","doi":"10.1038/d41573-025-00153-4","DOIUrl":"10.1038/d41573-025-00153-4","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"733-734"},"PeriodicalIF":101.8,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41573-025-00153-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145035753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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