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Nature Reviews. Drug Discovery最新文献

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Novel drug candidates for hard-to-treat hypertension vie for blockbuster positioning 治疗难治性高血压的新候选药物争夺重磅定位
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-08 DOI: 10.1038/d41573-025-00150-7
Asher Mullard
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引用次数: 0
FDA approves anti-prekallikrein drug for hereditary angioedema FDA批准用于遗传性血管性水肿的抗prekallikrein药物
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-08 DOI: 10.1038/d41573-025-00151-6
Asher Mullard
{"title":"FDA approves anti-prekallikrein drug for hereditary angioedema","authors":"Asher Mullard","doi":"10.1038/d41573-025-00151-6","DOIUrl":"10.1038/d41573-025-00151-6","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"732-732"},"PeriodicalIF":101.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41573-025-00151-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145009260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AbbVie bets on psychedelic drugs in Gilgamesh buy out 艾伯维在吉尔伽美什收购迷幻药
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-05 DOI: 10.1038/d41573-025-00149-0
Asher Mullard
{"title":"AbbVie bets on psychedelic drugs in Gilgamesh buy out","authors":"Asher Mullard","doi":"10.1038/d41573-025-00149-0","DOIUrl":"10.1038/d41573-025-00149-0","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"732-732"},"PeriodicalIF":101.8,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41573-025-00149-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144995212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First protease activator secures FDA approval for rare brain cancer 首个蛋白酶激活剂获FDA批准用于治疗罕见脑癌
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-05 DOI: 10.1038/d41573-025-00148-1
Asher Mullard
{"title":"First protease activator secures FDA approval for rare brain cancer","authors":"Asher Mullard","doi":"10.1038/d41573-025-00148-1","DOIUrl":"10.1038/d41573-025-00148-1","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"730-730"},"PeriodicalIF":101.8,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41573-025-00148-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144995436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combination therapy alleviates AD-related pathologies 联合治疗可减轻ad相关病理
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-03 DOI: 10.1038/d41573-025-00146-3
Sarah Crunkhorn
{"title":"Combination therapy alleviates AD-related pathologies","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-025-00146-3","DOIUrl":"10.1038/d41573-025-00146-3","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"742-742"},"PeriodicalIF":101.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Towards a broad-spectrum antiviral agent 研制广谱抗病毒药物
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-03 DOI: 10.1038/d41573-025-00145-4
Sarah Crunkhorn
{"title":"Towards a broad-spectrum antiviral agent","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-025-00145-4","DOIUrl":"10.1038/d41573-025-00145-4","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"742-742"},"PeriodicalIF":101.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potentiating the integrated stress response 增强综合应力反应
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-03 DOI: 10.1038/d41573-025-00147-2
Sarah Crunkhorn
{"title":"Potentiating the integrated stress response","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-025-00147-2","DOIUrl":"10.1038/d41573-025-00147-2","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"742-742"},"PeriodicalIF":101.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prime editing treats childhood neurological disease 主要编辑治疗儿童神经系统疾病
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-03 DOI: 10.1038/d41573-025-00144-5
Sarah Crunkhorn
{"title":"Prime editing treats childhood neurological disease","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-025-00144-5","DOIUrl":"10.1038/d41573-025-00144-5","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"742-742"},"PeriodicalIF":101.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Soluble Notch agonists drive T cell production 可溶性Notch激动剂驱动T细胞生成
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-09-02 DOI: 10.1038/d41573-025-00143-6
M. Teresa Villanueva
{"title":"Soluble Notch agonists drive T cell production","authors":"M. Teresa Villanueva","doi":"10.1038/d41573-025-00143-6","DOIUrl":"10.1038/d41573-025-00143-6","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"741-741"},"PeriodicalIF":101.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144928591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epigenetic inhibitor silences KRAS-driven oncogenes 表观遗传抑制剂沉默kras驱动的癌基因
IF 101.8 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2025-08-28 DOI: 10.1038/d41573-025-00142-7
Alex Eccleston
{"title":"Epigenetic inhibitor silences KRAS-driven oncogenes","authors":"Alex Eccleston","doi":"10.1038/d41573-025-00142-7","DOIUrl":"10.1038/d41573-025-00142-7","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"740-740"},"PeriodicalIF":101.8,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144911025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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