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Nature Reviews. Drug Discovery最新文献

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The unglamourous AI wins that are quietly transforming drug discovery and development 平淡无奇的人工智能正在悄然改变药物的发现和开发。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-12 DOI: 10.1038/d41573-026-00099-1
Asher Mullard
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引用次数: 0
Novel drug targets in 2025 2025年的新药物目标。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-12 DOI: 10.1038/d41573-026-00102-9
Sorin Avram,  Liliana Halip,  Ramona Curpan,  Alex Aliper,  Feng Ren,  Alex Zhavoronkov,  Tudor I. Oprea
{"title":"Novel drug targets in 2025","authors":"Sorin Avram, \u0000 Liliana Halip, \u0000 Ramona Curpan, \u0000 Alex Aliper, \u0000 Feng Ren, \u0000 Alex Zhavoronkov, \u0000 Tudor I. Oprea","doi":"10.1038/d41573-026-00102-9","DOIUrl":"10.1038/d41573-026-00102-9","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 7","pages":"503-503"},"PeriodicalIF":91.2,"publicationDate":"2026-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41573-026-00102-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148239704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antiviral peptide nabs FDA approval for hepatitis delta virus infection 抗病毒肽获FDA批准用于丁型肝炎病毒感染。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-11 DOI: 10.1038/d41573-026-00101-w
Asher Mullard
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引用次数: 0
First CD123-targeted ADC secures FDA approval for rare blood cancer 首个靶向cd123的ADC获FDA批准用于治疗罕见血癌
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-11 DOI: 10.1038/d41573-026-00100-x
Asher Mullard
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引用次数: 0
Evolution of the psoriasis therapy landscape 银屑病治疗前景的演变。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-10 DOI: 10.1038/d41573-026-00097-3
Kritika Chaudhari
{"title":"Evolution of the psoriasis therapy landscape","authors":"Kritika Chaudhari","doi":"10.1038/d41573-026-00097-3","DOIUrl":"10.1038/d41573-026-00097-3","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 10","pages":"752-753"},"PeriodicalIF":91.2,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148218767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancing ferroptosis-targeted therapies 推进铁中毒靶向治疗。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-10 DOI: 10.1038/d41573-026-00098-2
M. Teresa Villanueva
{"title":"Advancing ferroptosis-targeted therapies","authors":"M. Teresa Villanueva","doi":"10.1038/d41573-026-00098-2","DOIUrl":"10.1038/d41573-026-00098-2","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 7","pages":"513-513"},"PeriodicalIF":91.2,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148218830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implantable hydrogel encapsulates ‘living therapeutics’ 植入式水凝胶封装了“活疗法”。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-09 DOI: 10.1038/d41573-026-00096-4
Katie Kingwell
{"title":"Implantable hydrogel encapsulates ‘living therapeutics’","authors":"Katie Kingwell","doi":"10.1038/d41573-026-00096-4","DOIUrl":"10.1038/d41573-026-00096-4","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 7","pages":"514-514"},"PeriodicalIF":91.2,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148211907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of a decade of post-authorisation studies for medicines approved by the EMA EMA批准的药物10年的授权后研究分析。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-09 DOI: 10.1038/d41573-026-00082-w
Caroline Voltz-Girolt,  Guillem Wetherell Mateu,  Carla Torre,  Bruno Sepodes,  Harald Enzmann
{"title":"Analysis of a decade of post-authorisation studies for medicines approved by the EMA","authors":"Caroline Voltz-Girolt, \u0000 Guillem Wetherell Mateu, \u0000 Carla Torre, \u0000 Bruno Sepodes, \u0000 Harald Enzmann","doi":"10.1038/d41573-026-00082-w","DOIUrl":"10.1038/d41573-026-00082-w","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 7","pages":"504-505"},"PeriodicalIF":91.2,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41573-026-00082-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148218752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ASO sustains microglial neural repair activity ASO维持小胶质神经修复活动。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-08 DOI: 10.1038/d41573-026-00095-5
Alex Eccleston
{"title":"ASO sustains microglial neural repair activity","authors":"Alex Eccleston","doi":"10.1038/d41573-026-00095-5","DOIUrl":"10.1038/d41573-026-00095-5","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 7","pages":"511-511"},"PeriodicalIF":91.2,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148205673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply to ‘Stimulating medicines repurposing in the EU: a pilot project’ 回复“在欧盟刺激药物再利用：一个试点项目”。
IF 91.2 1区 医学
Nature Reviews. Drug Discovery Pub Date : 2026-06-08 DOI: 10.1038/s41573-026-01473-9
Pan Pantziarka, Patricia Vandamme, Alicia Soler, Gauthier Bouche, Donald C. Lo
{"title":"Reply to ‘Stimulating medicines repurposing in the EU: a pilot project’","authors":"Pan Pantziarka, Patricia Vandamme, Alicia Soler, Gauthier Bouche, Donald C. Lo","doi":"10.1038/s41573-026-01473-9","DOIUrl":"10.1038/s41573-026-01473-9","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 7","pages":"576-576"},"PeriodicalIF":91.2,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148205691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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