James F. Demarest, Ruxandra Draghia-Akli, Tomas Cihlar, Kenneth Bradley, John A. T. Young, Richa Chandra, Sujata Vaidyanathan, Margaret Chu-Moyer, Christopher L. Lynch, Andrew Campbell, Kumar Singh Saikatendu, John P. Bilello, Yoshihiko Murata, Marnix van Loock, Aeron C. Hurt, Timothy Tellinghuisen, Lee Ruggiero, Richard Mackman, Nina M. Hill, John C. Pottage
{"title":"Antiviral target compound profile for pandemic preparedness","authors":"James F. Demarest, Ruxandra Draghia-Akli, Tomas Cihlar, Kenneth Bradley, John A. T. Young, Richa Chandra, Sujata Vaidyanathan, Margaret Chu-Moyer, Christopher L. Lynch, Andrew Campbell, Kumar Singh Saikatendu, John P. Bilello, Yoshihiko Murata, Marnix van Loock, Aeron C. Hurt, Timothy Tellinghuisen, Lee Ruggiero, Richard Mackman, Nina M. Hill, John C. Pottage","doi":"10.1038/s41573-024-01102-3","DOIUrl":null,"url":null,"abstract":"<p>The recent experiences with the pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have demonstrated the urgent need for a structured approach towards accelerated and more effective discovery, development and delivery of vaccines, therapeutics, and diagnostics to minimize the overall impact of the next pandemic (see Related links). This urgency is further highlighted by the recent World Health Organization (WHO) declaration of a public health emergency of international concern for mpox (see Related links).</p>","PeriodicalId":18847,"journal":{"name":"Nature Reviews Drug Discovery","volume":"11 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Drug Discovery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1038/s41573-024-01102-3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The recent experiences with the pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have demonstrated the urgent need for a structured approach towards accelerated and more effective discovery, development and delivery of vaccines, therapeutics, and diagnostics to minimize the overall impact of the next pandemic (see Related links). This urgency is further highlighted by the recent World Health Organization (WHO) declaration of a public health emergency of international concern for mpox (see Related links).