Nature Communications最新文献_第10页

Field-resilient supercurrent diode in a multiferroic Josephson junction. 多铁Josephson结中的场弹性超电流二极管。

IF 15.7 1区综合性期刊

Nature Communications Pub Date : 2025-10-21 DOI: 10.1038/s41467-025-63698-3

Hung-Yu Yang, Joseph J Cuozzo, Anand Johnson Bokka, Gang Qiu, Christopher Eckberg, Yanfeng Lyu, Shuyuan Huyan, Ching-Wu Chu, Kenji Watanabe, Takashi Taniguchi, Kang L Wang

{"title":"Field-resilient supercurrent diode in a multiferroic Josephson junction.","authors":"Hung-Yu Yang, Joseph J Cuozzo, Anand Johnson Bokka, Gang Qiu, Christopher Eckberg, Yanfeng Lyu, Shuyuan Huyan, Ching-Wu Chu, Kenji Watanabe, Takashi Taniguchi, Kang L Wang","doi":"10.1038/s41467-025-63698-3","DOIUrl":"https://doi.org/10.1038/s41467-025-63698-3","url":null,"abstract":"<p><p>The research on supercurrent diodes has surged rapidly due to their potential applications in electronic circuits at cryogenic temperatures. To unlock this functionality, it is essential to find supercurrent diodes that can work consistently at zero magnetic field and under ubiquitous stray fields generated in electronic circuits. However, a supercurrent diode with robust field tolerance is currently lacking. Here, we demonstrate a field-resilient supercurrent diode by incorporating a 2D multiferroic material into a Josephson junction, and observed a pronounced supercurrent diode effect at zero magnetic field. More importantly, the supercurrent rectification persists over a wide and bipolar magnetic field range beyond industrial standards for field tolerance. By theoretically modeling a multiferroic Josephson junction, we unveil that the interplay between spin-orbit coupling and multiferroicity underlies the unusual field resilience of the observed diode effect. This work introduces multiferroic Josephson junctions as a new field-resilient superconducting device for cryogenic electronics.</p>","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"16 1","pages":"9287"},"PeriodicalIF":15.7,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145346343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Superintegrated conformable organic transistors based on a universal microlithographic strategy. 基于通用微光刻策略的超集成适形有机晶体管。

IF 16.6 1区综合性期刊

Nature Communications Pub Date : 2025-10-20 DOI: 10.1038/s41467-025-64284-3

Yanping Ni,Xiaoli Zhao,Chuang Xue,Jing Sun,Fanjunjie Han,Junru Zhang,Pengbo Xi,Yanhong Tong,Qingxin Tang,Yichun Liu

{"title":"Superintegrated conformable organic transistors based on a universal microlithographic strategy.","authors":"Yanping Ni,Xiaoli Zhao,Chuang Xue,Jing Sun,Fanjunjie Han,Junru Zhang,Pengbo Xi,Yanhong Tong,Qingxin Tang,Yichun Liu","doi":"10.1038/s41467-025-64284-3","DOIUrl":"https://doi.org/10.1038/s41467-025-64284-3","url":null,"abstract":"Conformable organic thin-film transistors (OTFTs) are identified as a core electronic component for next-generation wearable and implantable electronics. However, the lack of high-level integration of high-performance conformable devices remains a major obstacle to the commercialization of organic transistors. Here, a universal and non-destructive dual protective layer photolithography strategy is proposed, which is compatible with all organic materials, including conductors, semiconductors and insulators, with pattern precision of 0.5 µm. This approach enables the fabrication of ultrahigh-density OTFTs that demonstrate a mobility of 2.21 cm2V-1s-1 at a density of 64,288 transistors/cm2, scalable to scaled up to 5,120,000 transistors/cm2 while maintaining a mobility of ~1 cm2V-1s-1. Moreover, the devices show remarkable stability (10,000 switching cycles/100,000 folding cycles) and have been successfully integrated into sub-micron circuits and flexible displays, demonstrating strong application potential. This work offers a universal wafer-level manufacturing and integration pathway for ultrahigh-density, high-performance conformable devices, advancing the industrialization of conformable electronics.","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"1 1","pages":"9246"},"PeriodicalIF":16.6,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145331934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physics-based evolution of transmembrane helices reveals mechanisms of cholesterol attraction. 跨膜螺旋的物理进化揭示了胆固醇吸引的机制。

IF 16.6 1区综合性期刊

Nature Communications Pub Date : 2025-10-20 DOI: 10.1038/s41467-025-63769-5

Jeroen Methorst,Nino Verwei,Christian Hoffmann,Paweł Chodnicki,Roberto Sansevrino,Partha Pyne,Han Wang,Niek van Hilten,Dennis Aschmann,Alexander Kros,Loren Andreas,Jacek Czub,Dragomir Milovanovic,Herre Jelger Risselada

{"title":"Physics-based evolution of transmembrane helices reveals mechanisms of cholesterol attraction.","authors":"Jeroen Methorst,Nino Verwei,Christian Hoffmann,Paweł Chodnicki,Roberto Sansevrino,Partha Pyne,Han Wang,Niek van Hilten,Dennis Aschmann,Alexander Kros,Loren Andreas,Jacek Czub,Dragomir Milovanovic,Herre Jelger Risselada","doi":"10.1038/s41467-025-63769-5","DOIUrl":"https://doi.org/10.1038/s41467-025-63769-5","url":null,"abstract":"The existence of linear cholesterol-recognition motifs in transmembrane domains has long been debated. Evolutionary molecular dynamics (Evo-MD) simulations-genetic algorithms guided by (coarse-grained) molecular force-fields-reveal that thermodynamic optimal cholesterol attraction in isolated alpha-helical transmembrane domains occurs when multiple consecutive lysine/arginine residues flank a short hydrophobic segment. These findings are supported by atomistic simulations and solid-state NMR experiments. Our analyses illustrate that linear motifs in transmembrane domains exhibit weak binding affinity for cholesterol, characterized by sub-microsecond residence times, challenging the predictive value of linear CRAC/CARC motifs for cholesterol binding. Membrane protein database analyses suggest even weaker affinity for native linear motifs, whereas live cell assays demonstrate that optimizing cholesterol binding restricts transmembrane domains to the endoplasmic reticulum post-translationally. In summary, these findings contribute to our understanding of cholesterol-protein interactions and offer insight into the mechanisms of protein-mediated cholesterol regulation within membranes.","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"20 1","pages":"9275"},"PeriodicalIF":16.6,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145331966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resetting the clock by integrating urban nature and its biodiversity into the 15-minute city concept. 通过将城市自然及其生物多样性融入15分钟城市概念来重置时钟。

IF 16.6 1区综合性期刊

Nature Communications Pub Date : 2025-10-20 DOI: 10.1038/s41467-025-65170-8

Nadja Kabisch,Monika Egerer

引用次数: 0

Leveraging cation effect for low temperature aqueous Zn-based batteries. 低温水溶液锌基电池的利用阳离子效应。

IF 16.6 1区综合性期刊

Nature Communications Pub Date : 2025-10-20 DOI: 10.1038/s41467-025-64278-1

Doudou Feng,Yanchun Xie,Yucong Jiao,Peiyi Wu

引用次数: 0

SLEEPY: a comprehensive Python module for simulating relaxation and dynamics in nuclear magnetic resonance. 一个全面的Python模块，用于模拟核磁共振中的松弛和动态。

IF 16.6 1区综合性期刊

Nature Communications Pub Date : 2025-10-20 DOI: 10.1038/s41467-025-65091-6

Albert A Smith,Kai Zumpfe

{"title":"SLEEPY: a comprehensive Python module for simulating relaxation and dynamics in nuclear magnetic resonance.","authors":"Albert A Smith,Kai Zumpfe","doi":"10.1038/s41467-025-65091-6","DOIUrl":"https://doi.org/10.1038/s41467-025-65091-6","url":null,"abstract":"Nuclear magnetic resonance is a powerful method for characterizing dynamics of biological systems in a native-like environment. Accurate dynamics characterization, however, often requires simulations of complex NMR experiments. While a number of simulation programs exist for NMR simulation (SIMPSON, Spinach, SpinEvolution), none of these are focused on easy simulation of motional effects on NMR experiments. The SLEEPY Python module makes it straightforward to simulate arbitrary pulse sequences while including both relaxation and exchange processes. SLEEPY furthermore allows simulation of solid-state (static and spinning) and solution NMR experiments, using both truncated and full Hamiltonians (rotating frame/lab frame). We demonstrate its application to a wide variety of experiments, including transverse (T1ρ), and longitudinal relaxation (T1), nuclear Overhauser effect magnetization transfers, recoupling, and paramagnetic effects. We also provide an extensive online tutorial that explains how to use the various capabilities of SLEEPY. This tool can then be used for both better understanding of the impact of dynamics on NMR and in reproduction of experimental results.","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"12 1","pages":"9278"},"PeriodicalIF":16.6,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145332016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retraction Note: ROCK1 mechano-signaling dependency of human malignancies driven by TEAD/YAP activation. 注：由TEAD/YAP激活驱动的人类恶性肿瘤的ROCK1机械信号依赖性。

IF 15.7 1区综合性期刊

Nature Communications Pub Date : 2025-10-20 DOI: 10.1038/s41467-025-65053-y

Davide Esposito, Ila Pant, Yao Shen, Rui F Qiao, Xiaobao Yang, Yiyang Bai, Jian Jin, Poulikos I Poulikakos, Stuart A Aaronson

引用次数: 0

Temperature-dependent mechanism evolution on RhRu3Ox for acidic water oxidation. RhRu3Ox对酸性水氧化的温度依赖机理演化。

IF 16.6 1区综合性期刊

Nature Communications Pub Date : 2025-10-20 DOI: 10.1038/s41467-025-64286-1

Ming-Rong Qu,Heng Liu,Si-Hua Feng,Xiao-Zhi Su,Jie Xu,Heng-Li Duan,Rui-Qi Liu,You-Yi Qin,Wen-Sheng Yan,Sheng Zhu,Rui Wu,Hao Li,Shu-Hong Yu

{"title":"Temperature-dependent mechanism evolution on RhRu3Ox for acidic water oxidation.","authors":"Ming-Rong Qu,Heng Liu,Si-Hua Feng,Xiao-Zhi Su,Jie Xu,Heng-Li Duan,Rui-Qi Liu,You-Yi Qin,Wen-Sheng Yan,Sheng Zhu,Rui Wu,Hao Li,Shu-Hong Yu","doi":"10.1038/s41467-025-64286-1","DOIUrl":"https://doi.org/10.1038/s41467-025-64286-1","url":null,"abstract":"The oxygen evolution reaction, as the anodic reaction of many electrochemical devices, plays a crucial role in energy conversion. However, the insufficient stability of non-iridium-based materials during the oxygen evolution reaction has severely limited the large-scale application of such devices. Here, using a home-made operando differential electrochemical mass spectrometry system, we show a temperature dependent mechanism evolution effect of RhRu3Ox in the oxygen evolution process, which highlights the role of temperature in triggering mechanism evolution. This effect enriches the strategies for pathway manipulation. Since different kinetic pathways can influence catalyst stability, this finding suggests that temperature-dependent pathway regulation may serve as an approach to optimize stability. To evaluate the potential of RhRu3Ox for practical applications, we assemble it into a proton exchange membrane electrolyzer and demonstrate its stability at room temperature for over 1000 hours at a current density of 200 mA cm-2. Density functional theory studies suggest that the existence of a kinetic barrier related to lattice oxygen activation might be the reason for the observed temperature dependent behavior of RhRu3Ox at elevated temperatures.","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"32 1","pages":"9261"},"PeriodicalIF":16.6,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145331606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vegetation cover change as a growing driver of global leaf area index dynamics. 植被覆盖变化对全球叶面积指数动态的驱动作用。

IF 16.6 1区综合性期刊

Nature Communications Pub Date : 2025-10-20 DOI: 10.1038/s41467-025-64305-1

Dashan Wang,Alan D Ziegler,Joseph Holden,Dominick V Spracklen,Philippe Ciais,Liqing Peng,Zhenzhong Zeng

{"title":"Vegetation cover change as a growing driver of global leaf area index dynamics.","authors":"Dashan Wang,Alan D Ziegler,Joseph Holden,Dominick V Spracklen,Philippe Ciais,Liqing Peng,Zhenzhong Zeng","doi":"10.1038/s41467-025-64305-1","DOIUrl":"https://doi.org/10.1038/s41467-025-64305-1","url":null,"abstract":"The ongoing four-decade increase in global leaf area index (LAI), inferred from satellite observations, suggests enhanced carbon sequestration and evaporative cooling with potential benefits that may help mitigate climate warming. However, the role of vegetation cover change in driving these trends remains debated, raising concerns about the potential effects of reforestation and deforestation on ecosystem-climate interactions. Here, we develop a data-driven framework combining satellite-based observations to quantify the contributions of vegetation cover change to LAI dynamics across space and time. We find that vegetation cover change explains 18.1 ± 5.9% of the observed LAI increase since the 1980s, with pronounced contribution from increased tree cover primarily occurring in the northern hemisphere (33.8 ± 3.6%), partially offset by deforestation mainly taking place in the southern hemisphere (-15.7 ± 3.1%). Increases are most prominent in forestation regions such as China and Europe, while the sensitivity, defined as LAI change per unit percentage of tree cover gain, is lower than declines induced by deforestation in tropical areas. Our findings reveal that vegetation cover change is already, and increasingly, shaping global LAI dynamics to a greater extent than previously recognized, with important implications for future LAI trajectory projections, model development, and climate mitigation policies.","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"72 1","pages":"9259"},"PeriodicalIF":16.6,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145331930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CCL28 contributes to angiogenesis and cardiac repair through CCR10+ endothelial cells after myocardial infarction in male mice. ccr28通过CCR10+内皮细胞参与雄性小鼠心肌梗死后血管生成和心脏修复。

IF 16.6 1区综合性期刊

Nature Communications Pub Date : 2025-10-20 DOI: 10.1038/s41467-025-64283-4

Kun Yang,Hanchuan Chen,Yang Lyu,Wei Wei,Xiang Wei,Yunzhi Ling,Biting Lin,Gengyu Zhou,Juntao Chen,Jiaran Shi,Rifeng Gao,Kaiyang Lin

{"title":"CCL28 contributes to angiogenesis and cardiac repair through CCR10+ endothelial cells after myocardial infarction in male mice.","authors":"Kun Yang,Hanchuan Chen,Yang Lyu,Wei Wei,Xiang Wei,Yunzhi Ling,Biting Lin,Gengyu Zhou,Juntao Chen,Jiaran Shi,Rifeng Gao,Kaiyang Lin","doi":"10.1038/s41467-025-64283-4","DOIUrl":"https://doi.org/10.1038/s41467-025-64283-4","url":null,"abstract":"Secretome-based therapies that target angiogenesis are promising for the treatment of ischemic heart disease (IHD). The effects of Chemokine C-C motif ligand (CCL) 28 on IHD remain unclear. In this study, we investigated the role of CCL28 in angiogenesis during IHD in male mice using the myocardial infarction (MI) and hindlimb ischemia (HI) models. The upregulated CCL28/ C-C motif receptor (CCR)10 axis has been observed in HI and MI. Additionally, CCR10 is highly expressed in endothelial cells (ECs). Compared to CCR10- ECs, CCR10+ ECs exhibited robust proangiogenic capacity, which was induced by CCL28 through CCR10/ERK/SOX5 positive feedback signaling. The deletion of CCL28 results in impaired angiogenesis, whereas the use of recombinant CCL28 protein has therapeutic potential for myocardial and hindlimb ischemia, including that in diabetes. Endothelial-specific CCR10 deficiency impairs angiogenesis and blocks the therapeutic effects of rCCL28 in ischemic models. Serum CCL28 levels have a predictive effect on coronary collateral vessels (CCV) in patients with chronic total occlusions. This study highlights the angiogenic role of CCL28 and suggests that recombinant CCL28 protein may be a potential therapeutic option to attenuate IHD.","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"28 1","pages":"9262"},"PeriodicalIF":16.6,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145331967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0