Mycotoxin Research最新文献

{"title":"Occurrence and health risk assessment of AFM1 in commercial yogurt in Thailand.","authors":"Usa Ekaluckrujee, Chamawan Buated, Natthamon Vanigorn, Thanaporn Sriprathardtrakul, Saranya Poapolathep, Phattarawadee Wattanasuntorn, Johanna Fink-Gremmels, Amnart Poapolathep","doi":"10.1007/s12550-026-00641-5","DOIUrl":"10.1007/s12550-026-00641-5","url":null,"abstract":"<p><p>Milk and dairy products, including yogurt, provide essential nutrients and are widely consumed as valuable protein sources. However, considering then increasing prevalence of Aflatoxin B1 (AFB1) in the diet of dairy cows, concerns arise regarding the possible contamination of milk and dairy products with AFM1, the major metabolite of AFB1 excreted in the milk of lactating animals. AFM1, although less potent when compared to AFB1, has been associated with an increase in the prevalence of human hepatic carcinoma. Hence, following a survey on AFM1 contamination of raw and processed drinking milk, this study aimed to evaluate the occurrence of aflatoxin M1 (AFM1) in yogurt available in Bangkok, Thailand, and to estimate the associated dietary exposure and health risk among different population groups. A total of 180 plain yogurt samples were randomly collected from supermarkets during March to June 2024. The samples were extracted using the QuEChERS methodology and analyzed using a validated liquid chromatography- tandem mass spectrometry method. With this method, residual amounts of AFM1 were detected in 12 out of 180 yoghurt samples, with concentrations ranging from 0.031 to 0.048 µg/kg. These levels are below the statutory limits set by the European Union and the FAO/WHO Joint Expert Committee. In addition, a quantitative risk assessment conducted for the AFM1 positive samples revealed that the margin of exposure (MOE) values derived for yogurt were above 10,000. The risk level of hepatocellular carcinoma due to AFM1 exposure expressed as the mean estimated number of liver cancer cases per 100,000 individuals per year ranged from 1.12 × 10^- 7 to 1.33 × 10^- 4 for the positive yogurt samples. Although the overall risk of AFM1 exposure is considered low for all age groups, children remain the most vulnerable population; therefore, continuous monitoring of dairy milk and milk products is warranted to minimize potential exposure.</p>","PeriodicalId":19060,"journal":{"name":"Mycotoxin Research","volume":"42 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147308085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current status of aflatoxin contamination and mitigation efforts in mozambique: a systematic review.","authors":"Ibraimo Teleha Chabite, Jamal Kussaga, Frida Nyamete, Rashid Suleiman","doi":"10.1007/s12550-026-00638-0","DOIUrl":"10.1007/s12550-026-00638-0","url":null,"abstract":"","PeriodicalId":19060,"journal":{"name":"Mycotoxin Research","volume":"42 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147317779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ochratoxin A in bulk consignments of wheat, durum wheat, and barley sampled before and after trans-Pacific shipment.","authors":"Sheryl A Tittlemier, Atsushi Sekiyama, Yukiko Yamada","doi":"10.1007/s12550-026-00642-4","DOIUrl":"10.1007/s12550-026-00642-4","url":null,"abstract":"","PeriodicalId":19060,"journal":{"name":"Mycotoxin Research","volume":"42 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12929274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147276696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maize inoculation with aflatoxigenic and biocontrol fungi - toxin transfer from feed into milk and yoghurt.","authors":"Julika Lamp, Karin Knappstein, Christine Schwake-Anduschus, Stefan Nöbel, Janine Saltzmann, Sven Dänicke, Markus Schmidt-Heydt, Ronald Maul","doi":"10.1007/s12550-026-00634-4","DOIUrl":"10.1007/s12550-026-00634-4","url":null,"abstract":"","PeriodicalId":19060,"journal":{"name":"Mycotoxin Research","volume":"42 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12926233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147271517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dipsacoside B alleviates aflatoxin B1-induced liver injury in mice.","authors":"Sicong Li, Min Zhang, Bin Wang, Ge Liang, Xuting Li","doi":"10.1007/s12550-026-00639-z","DOIUrl":"https://doi.org/10.1007/s12550-026-00639-z","url":null,"abstract":"","PeriodicalId":19060,"journal":{"name":"Mycotoxin Research","volume":"42 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146257964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aflatoxin B₁ contamination and fungal diversity in oilseed cakes and formulated feeds from livestock feed markets in Addis Ababa and surrounding areas.","authors":"Adey Melesse Yalew, Alemayehu Teressa Negawo, Tesfaye Alemu, Jean Hanson, Michael Blummel, Nebiyat Nigusie Woldeyohannis, Yilikal Assefa Teferi, Yonas Asmare, Prasad Kodukula V S V, Chris S Jones","doi":"10.1007/s12550-025-00630-0","DOIUrl":"10.1007/s12550-025-00630-0","url":null,"abstract":"","PeriodicalId":19060,"journal":{"name":"Mycotoxin Research","volume":"42 2","pages":"24"},"PeriodicalIF":3.1,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12917036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146220333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contribution of terrestrial processes in reducing environmental mycotoxin levels: a review on mycotoxin-soil interactions.","authors":"Katherine Muñoz, Sven Korz, Maximilian Meyer, Beatrice Berger","doi":"10.1007/s12550-026-00635-3","DOIUrl":"10.1007/s12550-026-00635-3","url":null,"abstract":"","PeriodicalId":19060,"journal":{"name":"Mycotoxin Research","volume":"42 2","pages":"23"},"PeriodicalIF":3.1,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12891044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146156189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycotoxin occurrence and risk assessment in plant-based meat, cheese, and fish alternatives based on an adapted UHPLC-MS/MS multi-method.","authors":"Sarah Schneidemann-Bostelmann, Yannick Otting, Fabian Dick, Thijs Lefever, Stefan Asam, Michael Rychlik","doi":"10.1007/s12550-026-00636-2","DOIUrl":"10.1007/s12550-026-00636-2","url":null,"abstract":"<p><p>Plant-based alternatives to animal-derived products have gained significant prominence in recent years, with the market for these products experiencing continuous growth. In response to this trend, we developed an ultra-high-performance liquid chromatography method, coupled with tandem mass spectrometry (UHPLC-MS/MS) for the simultaneous quantification of 15 mycotoxins from Fusarium (deoxynivalenol (DON), DON-3-glucoside (D3G), 3-acetyl-DON, 15-acetyl-DON, HT-2 toxin, T-2 toxin), Alternaria (alternariol, alternariolmonomethylether (AME), tenuazonic acid (TeA)), and Aspergillus species (aflatoxin (AF) B1, B2, G1, G2, sterigmatocystin (STC), ochratoxin A) in plant-based meat, cheese, and fish substitutes. Sample extraction was performed using a QuEChERS (quick, easy, cheap, effective, rugged, and safe) approach, followed by dispersive solid phase extraction (dSPE) for clean-up. Quantification was achieved through stable isotope dilution analysis (SIDA). The method demonstrated limits of detection (LOD) ranging from 0.01 µg/kg (AFB2 and STC) to 14.1 µg/kg (D3G) and limits of quantification (LOQ) between 0.02 µg/kg (STC) and 41.9 µg/kg (D3G). This method was successfully applied to quantify mycotoxins in 32 plant-based alternative products, revealing contamination predominantly with Alternaria toxins such as AME and TeA. Seitan-based products were identified as having the highest levels of contamination. In total, 27 out of 32 analyzed products contained at least one of the target mycotoxins. With the obtained data, we performed a risk assessment and revealed a potential risk, especially for toddlers, but also for individuals of all ages, due to the presence of Alternaria toxins. However, none of the detected concentrations exceeded the established regulatory limits or recommended values, as plant-based alternatives are not specifically included in the relevant food safety regulations.</p>","PeriodicalId":19060,"journal":{"name":"Mycotoxin Research","volume":"42 1","pages":"22"},"PeriodicalIF":3.1,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12868108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146113666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of mycotoxin contamination in different types of tea: a systematic review and meta-analysis.","authors":"Morad Guennouni, Nysrine Mannani, Abdellah Zinedine, Ider Oujamaa, Rachid Nmila, Abderraouaf Hilali, Ana Juan-Garcia, Brahim Admou","doi":"10.1007/s12550-025-00620-2","DOIUrl":"10.1007/s12550-025-00620-2","url":null,"abstract":"<p><p>The consumption of tea as a beverage is considerably increasing worldwide. However, some questions are raised about its safety, particularly regarding the potential contamination by mycotoxins. The objectives of this systematic review and meta-analysis were to assess the overall prevalence of mycotoxin contamination in different types of tea (black, green, dark, white and pu-erh), to compare the contamination rate between two periods (2000-2017 and 2018-2022), and to investigate the impact of country's income on this contamination. Included studies were selected from Scopus, Science Direct, Web of Science, PubMed and Google Scholar research databases, according to PRISMA guidelines. Statistical analysis was performed using MecdCalc software. Concerning the analytical methods used for mycotoxin detection, 84.6% of included studies used HPLC and or LC-MS/MS. In the 21 included studies, the mycotoxin contamination was predominantly by deoxynivalenol, with 43.8% (95% CI: 8.2%- 83.8%), followed by ochratoxin A (29.1% (95% CI: 11.9%- 50.2%)), enniatin (23.7% (95% CI: 1.7%- 60.1%)), citrinin (23.6% (95% CI: 6.2%- 47.8%)), zearalenone (17.8% (95% CI: 5.1%- 36.0%)), and aflatoxins (12.4% (95% CI: 7.8%- 17.9%)). Regarding tea categories, black tea was the most contaminated type, with a rate of 89.2% (95% CI: 73.9%-98.3%), followed by green tea with a rate of 67.3% (95% CI: 37.0%-91.2%). The contamination prevalence was higher in studies conducted before 2018 than those of the 2018-2022 period, and lower in high-income countries compared to middle and low-income countries, where tea contamination was rarely reported. Therefore, more stringent prevention strategies, including regulatory measures, are needed to decrease the risk of tea consumers exposure to mycotoxins.</p>","PeriodicalId":19060,"journal":{"name":"Mycotoxin Research","volume":"42 1","pages":"21"},"PeriodicalIF":3.1,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146106248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occurrence of mycotoxins in fish feed and its consequences for aquaculture with special regard to the role of insect products.","authors":"Mikołaj Bittner, Paweł Brzuzan, Maciej Woźny","doi":"10.1007/s12550-025-00628-8","DOIUrl":"10.1007/s12550-025-00628-8","url":null,"abstract":"","PeriodicalId":19060,"journal":{"name":"Mycotoxin Research","volume":"42 1","pages":"20"},"PeriodicalIF":3.1,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12827404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146018648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}