Nature nanotechnology最新文献_第6页

Strain-induced crumpling of graphene oxide lamellas to achieve fast and selective transport of H2 and CO2 应变诱导的氧化石墨烯薄片的皱缩，以实现H2和CO2的快速和选择性运输

IF 34.9 1区材料科学

Nature nanotechnology Pub Date : 2025-07-14 DOI: 10.1038/s41565-025-01971-8

Pengxiang Zhang, Qian Wang, Yixin Zhang, Mo Lin, Xin Zhou, Ashish David, Andrey Ustyuzhanin, Musen Chen, Mikhail I. Katsnelson, Maxim Trubyanov, Kostya S. Novoselov, Daria V. Andreeva

{"title":"Strain-induced crumpling of graphene oxide lamellas to achieve fast and selective transport of H2 and CO2","authors":"Pengxiang Zhang, Qian Wang, Yixin Zhang, Mo Lin, Xin Zhou, Ashish David, Andrey Ustyuzhanin, Musen Chen, Mikhail I. Katsnelson, Maxim Trubyanov, Kostya S. Novoselov, Daria V. Andreeva","doi":"10.1038/s41565-025-01971-8","DOIUrl":"10.1038/s41565-025-01971-8","url":null,"abstract":"Graphene oxide (GO) membranes offer high selectivity and energy-efficient gas separation. However, their dense, layered structure and tortuous diffusion paths limit permeability, posing a barrier to industrial use. Here we present a method to enhance selectivity and permeability, maintaining the structural stability of such membranes. With an industrially friendly manufacturing method, we produce crumpled GO membranes with gas diffusion pathways controlled by a multidomain structure. These membranes achieve H2 permeability of approximately 2.1 × 104 barrer, significantly surpassing the permeability of flat lamellar GO membranes, which is below 100 barrer. Its H2/CO2 selectivity of 91 outperforms current membrane technologies. In addition, the crumpled membranes demonstrate stability under harsh conditions (−20 °C, 96% relative humidity), a critical requirement for practical applications. This work addresses the long-standing permeability–selectivity trade-off and establishes a robust, scalable platform for integrating two-dimensional materials into membrane technology for real-world applications. Crumpled graphene oxide (GO) membranes achieve much higher H2 permeability than flat lamellar GO membranes, and their H2/CO2 selectivity of 91 outperforms those of most existing membranes.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 9","pages":"1254-1261"},"PeriodicalIF":34.9,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144622424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Iron–silver-modified quantum dots act as efficient catalysts in anti-cancer multitherapy through controlled, ultrasound-induced oxidation 铁银修饰量子点作为有效的催化剂，通过控制，超声诱导氧化抗癌综合治疗

IF 34.9 1区材料科学

Nature nanotechnology Pub Date : 2025-07-10 DOI: 10.1038/s41565-025-01943-y

Dong Wang, Lei Ji, You Li, Meng Xu, Hao Wang, Sergio Brovelli, Zeng-Ying Qiao, Jiatao Zhang, Yadong Li

{"title":"Iron–silver-modified quantum dots act as efficient catalysts in anti-cancer multitherapy through controlled, ultrasound-induced oxidation","authors":"Dong Wang, Lei Ji, You Li, Meng Xu, Hao Wang, Sergio Brovelli, Zeng-Ying Qiao, Jiatao Zhang, Yadong Li","doi":"10.1038/s41565-025-01943-y","DOIUrl":"10.1038/s41565-025-01943-y","url":null,"abstract":"Chemodynamic therapy and sonodynamic therapy are two promising tumour therapeutic strategies. However, lack of highly effective sonosensitizers and control over chemodynamic therapy limit their application. Here we synthesize silver-doped zinc selenide quantum dots with atomically dispersed superficial Fe and show that they act as efficient sonosensitizers, catalysers and immunoreagents. Surface modification with an in situ self-assembly peptide drives accumulation in tumours. Superficial FeIII remains stable and converts to FeII only under ultrasonic processing, reverting to FeIII upon ultrasound cessation. Under ultrasound stimulation, superficial Fe undergoes valence change with concomitant amelioration of the hypoxic tumour microenvironment and production of sonodynamic therapy-beneficial hydroxyl radicals. Furthermore, silver doping suppressed nonradiative recombination of excitons, leading to improved production of singlet oxygen. Meanwhile, selenium promotes robust systemic immune responses for the inhibition of tumour metastases. This nano-platform allows control of valence switching of atomically dispersed catalysts, representing an effective tool for chemodynamic/sonodynamic/immunotherapy. Atomically dispersed surficial iron in silver-doped zinc selenide quantum dots with an in situ self-assembly peptide act as efficient catalysts in anti-cancer multitherapy through controlled, ultrasound-induced oxidation.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 8","pages":"1098-1107"},"PeriodicalIF":34.9,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144594140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vortex lasers through collective boundary scattering 涡旋激光通过集体边界散射

IF 34.9 1区材料科学

Nature nanotechnology Pub Date : 2025-07-01 DOI: 10.1038/s41565-025-01970-9

Qiang Zhang, Xiaocong Yuan

引用次数: 0

Observation of chiral emission enabled by collective guided resonances 集体引导共振实现手性发射的观察

IF 34.9 1区材料科学

Nature nanotechnology Pub Date : 2025-07-01 DOI: 10.1038/s41565-025-01964-7

Ye Chen, Mingjin Wang, Jiahao Si, Zixuan Zhang, Xuefan Yin, Jingxuan Chen, Nianyuan Lv, Chenyan Tang, Wanhua Zheng, Yuri Kivshar, Chao Peng

{"title":"Observation of chiral emission enabled by collective guided resonances","authors":"Ye Chen, Mingjin Wang, Jiahao Si, Zixuan Zhang, Xuefan Yin, Jingxuan Chen, Nianyuan Lv, Chenyan Tang, Wanhua Zheng, Yuri Kivshar, Chao Peng","doi":"10.1038/s41565-025-01964-7","DOIUrl":"10.1038/s41565-025-01964-7","url":null,"abstract":"A simple yet insightful question is whether it is possible to arrange optical resonances in such a way that their collective response differs from that of the individual constituents. Here, inspired by the collective oscillation of spatially localized modes and Fourier duality between real and momentum spaces, we demonstrate a chiral emission of collective guided modes by leveraging the omnidirectional hybridization of individual guided resonances within a photonic crystal slab. Specifically, we encircle a uniform photonic crystal with isotropic boundaries and hybridize discrete bulk guided resonances into a series of collective modes owing to the scatterings of the boundaries. This results in a chiral spiral vortex emission in real space. By using asymmetric pumping to lift the chiral symmetry, we then achieve stable single-mode lasing oscillation of the spiral collective mode and confirm the nature of vortex emission through polarization-resolved imaging and self-interference patterns, thus demonstrating a vivid example of collective oscillations in the momentum space. Chiral emission from collective guided modes is demonstrated within a photonic crystal slab, showing an example of collective oscillations in the momentum space.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 9","pages":"1205-1212"},"PeriodicalIF":34.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41565-025-01964-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144521098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanopore detection of single-nucleotide RNA mutations and modifications with programmable nanolatches 单核苷酸RNA突变和修饰的纳米孔检测与可编程纳米贴片

IF 38.3 1区材料科学

Nature nanotechnology Pub Date : 2025-06-27 DOI: 10.1038/s41565-025-01965-6

Yunxuan Li, Siong Chen Meng, Yesheng Wang, Casey M. Platnich, Max K. Earle, Elli Mylona, Plamena Naydenova, Stephen Baker, Jinbo Zhu, Ulrich F. Keyser

{"title":"Nanopore detection of single-nucleotide RNA mutations and modifications with programmable nanolatches","authors":"Yunxuan Li, Siong Chen Meng, Yesheng Wang, Casey M. Platnich, Max K. Earle, Elli Mylona, Plamena Naydenova, Stephen Baker, Jinbo Zhu, Ulrich F. Keyser","doi":"10.1038/s41565-025-01965-6","DOIUrl":"https://doi.org/10.1038/s41565-025-01965-6","url":null,"abstract":"RNA mutations and modifications have been implicated in a wide range of pathophysiologies. However, current RNA detection methods are hindered by data complexity and error-prone protocols, restricting their widespread use. Here we present a solid-state nanopore-based approach, RNA single-nucleotide characterization and analysis nanolatch (RNA-SCAN) system, which simplifies the detection of nucleotide mutations and modifications in RNA with high resolution. Using phage RNA as a template, we tested multiple sequences and chemical modifications on nanolatches, allowing the detection of mismatches caused by nucleotide mutations through significant changes in positive event ratios using single-molecule nanopore measurements. This approach is also sensitive to modifications that either strengthen or weaken the interaction between the target RNA sequence and the nanolatch. As a proof-of-concept, we demonstrate successful discrimination of Escherichia coli and Salmonella spp. from total RNA based on nucleotide variations in their 16S rRNA, as well as quantification of different Salmonella spp. and detection of m5C1407 modification on E. coli 16S rRNA. The RNA-SCAN approach demonstrates the feasibility of combining RNA/DNA hybrid nanotechnology with nanopore sensing and diagnosing RNA-related health conditions.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"46 1","pages":""},"PeriodicalIF":38.3,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144500490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

States of shear wander 剪切漂移状态

IF 34.9 1区材料科学

Nature nanotechnology Pub Date : 2025-06-26 DOI: 10.1038/s41565-025-01960-x

Conor J. McCluskey, John Marty Gregg

引用次数: 0

A NICER nanovaccine for cancer immunotherapy 用于癌症免疫治疗的更好的纳米疫苗

IF 34.9 1区材料科学

Nature nanotechnology Pub Date : 2025-06-25 DOI: 10.1038/s41565-025-01953-w

引用次数: 0

Tailoring the adjuvanticity of lipid nanoparticles by PEG lipid ratio and phospholipid modifications 通过PEG脂质比例和磷脂修饰来剪裁脂质纳米颗粒的佐剂性

IF 34.9 1区材料科学

Nature nanotechnology Pub Date : 2025-06-23 DOI: 10.1038/s41565-025-01958-5

Máté Vadovics, Wenchen Zhao, Emily F. Daley, Kieu Lam, Owen Daly, Khalid Rashid, Hailey R. Lee, Petra Schreiner, Kendall A. Lundgreen, Brian T. Gaudette, Vladimir V. Shuvaev, Evguenia Arguiri, Hiromi Muramatsu, András Sárközy, Thandiswa Mdluli, Junchao Xu, Xuexiang Han, Nina De Luna, Diana Castaño, Emily Bettini, Edit Ábrahám, Zoltan Lipinszki, Giuseppe Carlucci, Avinash Haridas Bansode, Katelyn Nguyen, Thuc M. Le, Tony Luu, Vladimir R. Muzykantov, Paul Bates, David Allman, Michael J. Mitchell, Michela Locci, Caius G. Radu, James Heyes, Norbert Pardi

{"title":"Tailoring the adjuvanticity of lipid nanoparticles by PEG lipid ratio and phospholipid modifications","authors":"Máté Vadovics, Wenchen Zhao, Emily F. Daley, Kieu Lam, Owen Daly, Khalid Rashid, Hailey R. Lee, Petra Schreiner, Kendall A. Lundgreen, Brian T. Gaudette, Vladimir V. Shuvaev, Evguenia Arguiri, Hiromi Muramatsu, András Sárközy, Thandiswa Mdluli, Junchao Xu, Xuexiang Han, Nina De Luna, Diana Castaño, Emily Bettini, Edit Ábrahám, Zoltan Lipinszki, Giuseppe Carlucci, Avinash Haridas Bansode, Katelyn Nguyen, Thuc M. Le, Tony Luu, Vladimir R. Muzykantov, Paul Bates, David Allman, Michael J. Mitchell, Michela Locci, Caius G. Radu, James Heyes, Norbert Pardi","doi":"10.1038/s41565-025-01958-5","DOIUrl":"10.1038/s41565-025-01958-5","url":null,"abstract":"Lipid nanoparticles (LNPs) represent the leading delivery platform for mRNA vaccines with advantageous biocompatibility, scalability, adjuvant activity and often an acceptable safety profile. Here we investigate the physicochemical characteristics and adjuvanticity of four-component LNPs. Previous vaccine studies have demonstrated that altering the ionizable lipid influences the adjuvanticity of an LNP; however, the impact of the polyethylene glycol lipid and phospholipid has received less attention. Our mRNA–LNP vaccine formulations utilized different phospholipids and varying ratios of polyethylene glycol lipid, whereas the ionizable lipid and cholesterol remained approximately constant. We demonstrate that such modifications impact the magnitude and quality of the vaccine-elicited immune responses. We also dissect the underlying mechanisms and show that the biodistribution and cellular uptake of LNPs correlate with the magnitude and quality of the immune responses. These findings support the rational design of novel LNPs to tailor immune responses (cellular or humoral focused) based on the vaccine application. Modifying the polyethylene glycol lipid ratio and phospholipids in the lipid nanoparticle component of nucleoside-modified mRNA–lipid nanoparticle vaccines is shown to have an impact on the elicited cellular and humoral immune responses.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 9","pages":"1312-1322"},"PeriodicalIF":34.9,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144341328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nonlinear Nernst effect in trilayer graphene at zero magnetic field 零磁场下三层石墨烯的非线性能子效应

IF 34.9 1区材料科学

Nature nanotechnology Pub Date : 2025-06-23 DOI: 10.1038/s41565-025-01963-8

Hao Liu, Jingru Li, Zhifan Zhang, Jinfeng Zhai, Min Zhang, Hua Jiang, X. C. Xie, Pan He, Jian Shen

{"title":"Nonlinear Nernst effect in trilayer graphene at zero magnetic field","authors":"Hao Liu, Jingru Li, Zhifan Zhang, Jinfeng Zhai, Min Zhang, Hua Jiang, X. C. Xie, Pan He, Jian Shen","doi":"10.1038/s41565-025-01963-8","DOIUrl":"10.1038/s41565-025-01963-8","url":null,"abstract":"The Nernst effect, that is, the generation of a transverse voltage in response to a temperature gradient, enables thermoelectric energy conversion. In the absence of an external magnetic field, the linear Nernst effect is forbidden in non-magnetic materials because of time-reversal symmetry constraints, but the recently predicted nonlinear Nernst effect (NNE) is allowed. Here we report the experimental observation of the NNE in non-magnetic ABA trilayer graphene, even in the absence of an external magnetic field. This effect is detected via electric harmonic measurements under an alternating temperature gradient at temperatures below 12 K. The NNE exhibits a quadratic dependence on the temperature gradient. It is notably enhanced near the charge neutrality point and reaches a giant effective Nernst coefficient of up to 300 µV K−1 at 2 K, surpassing the linear coefficients of magnetic materials. Moreover, we establish a scaling law between the NNE and the linear Seebeck effect, confirming the dominance of a skew scattering mechanism in driving the NNE. Our findings demonstrate an alternative approach for thermoelectric energy harvesting and cooling applications via nonlinear thermoelectric responses, which may, in the long run, offer alternative approaches towards the development of advanced thermoelectric devices. In ABA trilayer graphene, a temperature gradient generates a transverse voltage that scales quadratically with the gradient and reaches an effective Nernst coefficient of 300 µV K−1 near the charge neutrality point.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 9","pages":"1221-1227"},"PeriodicalIF":34.9,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144341329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mesoscale dynamics of electrosorbed ions in fast-charging carbon-based nanoporous electrodes 快速充电碳基纳米孔电极中电吸附离子的中尺度动力学

IF 34.9 1区材料科学

Nature nanotechnology Pub Date : 2025-06-23 DOI: 10.1038/s41565-025-01947-8

Peiyao Wang, Ke Zhang, Jinsha Liao, Xiao Wang, George P. Simon, Jefferson Zhe Liu, Dan Li

{"title":"Mesoscale dynamics of electrosorbed ions in fast-charging carbon-based nanoporous electrodes","authors":"Peiyao Wang, Ke Zhang, Jinsha Liao, Xiao Wang, George P. Simon, Jefferson Zhe Liu, Dan Li","doi":"10.1038/s41565-025-01947-8","DOIUrl":"10.1038/s41565-025-01947-8","url":null,"abstract":"Electrosorption, the accumulation of electrolyte ions at charged interfaces, is a common phenomenon across various electrochemical systems. Its impact is particularly pronounced in nanoporous electrodes owing to their high surface-to-volume ratios. Although electrosorption alters the ion distribution at the electrode–electrolyte interface through the formation of an electrical double layer, the effects of electrosorbed ions on the charge storage dynamics in nanoporous electrodes and their ability to improve charging processes have often been overlooked. Here we use a multilayered reduced graphene oxide-based membrane as a model nanoporous electrode material, integrating numerical simulations with experimental insights. We monitor the spatiotemporal distribution of electrosorbed ions and electrical potentials across the nanopore network during fast charging of symmetrical laboratory-scale cells using aqueous and non-aqueous electrolyte solutions. This method allowed us to quantitatively assess how features of the nanoporous electrode mesostructure, such as nanoslit size, the distribution of nanoslit sizes and electrode thickness, dynamically influence ion electrosorption and the local electrical and chemical potentials across the network. Our findings reveal that the mesostructure of nanoporous electrodes influences how migration and diffusion currents, mediated by electrosorbed ions, respond to charging rates. This study demonstrates how the mesostructure of nanoporous carbon electrodes influences ion dynamics, providing mechanistic insights and strategies for the technological advancement of fast-charging electrochemical energy storage systems.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"20 9","pages":"1228-1236"},"PeriodicalIF":34.9,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144341331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0