Nature and Science of Sleep最新文献

{"title":"Sleep Deprivation Selectively Impairs Interpersonal Trust in Different Social Scenarios: Evidence from the Social Mindfulness Paradigm.","authors":"Wenwei Zhu, Tianxiang Jiang, Yixuan Cao, Ning Ma","doi":"10.2147/NSS.S504467","DOIUrl":"10.2147/NSS.S504467","url":null,"abstract":"<p><strong>Background: </strong>Sleep deprivation (SD) is widely recognized for its negative impact on both cognitive abilities and social interactions. Nonetheless, the effect of sleep deprivation on interpersonal trust in social scenarios is poorly understood.</p><p><strong>Purpose: </strong>This study investigated the impact of total sleep deprivation on interpersonal trust under two different social scenarios: kindness and unkindness.</p><p><strong>Patients and methods: </strong>All participants (N = 49) completed the Social Mindfulness paradigm (SoMi) after both normal sleep (NS) and SD. Alertness changes were assessed using the Psychomotor Vigilance test (PVT) and the Karolinska Sleepiness Scale (KSS).</p><p><strong>Results: </strong>Our results demonstrated that SD significantly impaired interpersonal trust when perceiving unkind intentions but did not affect trust in kind intentions (<i>p</i> < 0.05). Additionally, this detrimental effect was not related to changes in alertness (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>These findings suggest that SD selectively impacts interpersonal trust, and this effect is not influenced by simple cognitive functions such as alertness. Further research could incorporate brain imaging techniques to explore the association of other cognitive and affective factors with interpersonal trust after sleep loss.</p>","PeriodicalId":18896,"journal":{"name":"Nature and Science of Sleep","volume":"17 ","pages":"531-541"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11972003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-Time Snoring Detection Using Deep Learning: A Home-Based Smartphone Approach for Sleep Monitoring.","authors":"Joonki Hong, Seung Koo Yang, Seunghun Kim, Sung-Woo Cho, Jayoung Oh, Eun Sung Cho, In-Young Yoon, Dongheon Lee, Jeong-Whun Kim","doi":"10.2147/NSS.S514631","DOIUrl":"10.2147/NSS.S514631","url":null,"abstract":"<p><strong>Background: </strong>Despite the prevalence of sleep-related disorders, few studies have developed deep learning models to predict snoring using home-recorded smartphone audio. This study proposes a real-time snoring detection method utilizing a Vision Transformer-based deep learning model and smartphone recordings.</p><p><strong>Methods: </strong>Participants' sleep-breathing sounds were recorded using smartphones, with concurrent Level I or II polysomnography (PSG) conducted in home or hospital settings. A total of 200 minutes of smartphone audio per participant, corresponding to 400 30-second sleep stage epochs on PSG, were sampled. Each epoch was annotated independently by two trained labelers, with snoring labeled only when both agreed. Model performance was evaluated by epoch-by-epoch prediction accuracy and correlation between observed and predicted snoring ratios.</p><p><strong>Results: </strong>The study included 214 participants (85,600 epochs). Hospital audio data from 105 participants (42,000 epochs) were used for training, while home audio data from 109 participants were split into 54 participants (21,600 epochs) for training and 55 participants (22,000 epochs) for testing. On the test dataset, the model demonstrated a sensitivity of 89.8% and a specificity of 91.3%. Correlation analysis showed strong agreement between observed and predicted snoring ratios (r = 0.97, 95% CI: 0.95-0.99).</p><p><strong>Conclusion: </strong>This study demonstrates the feasibility of using deep learning for real-time snoring detection from home-recorded smartphone audio. With high accuracy and scalability, the approach offers a practical and accessible tool for monitoring sleep-related disorders, paving the way for home-based sleep health management solutions.</p>","PeriodicalId":18896,"journal":{"name":"Nature and Science of Sleep","volume":"17 ","pages":"519-530"},"PeriodicalIF":3.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Quality of Patients on a General Department During the First Days of Hospitalization.","authors":"Hana Locihová, Darja Jarošová, Karolína Šrámková, Jana Slonkova, Renáta Zoubková, Klára Maternová, Karel Sonka","doi":"10.2147/NSS.S501743","DOIUrl":"10.2147/NSS.S501743","url":null,"abstract":"<p><strong>Purpose: </strong>The main aim of the study was to record subjective assessment of sleep quality between men and woman in hospitalised patients over 3 nights and look for associations with other basic hospitalisation data (age, type of department, surgery, pain, type of admission, previous hospitalisation, sleep-inducing medication). The secondary aim was to determine whether the <i>Ford Insomnia Response to Stress Test</i> (FIRST) questionnaire is an appropriate tool for identifying hospitalised individuals prone to situational sleep disturbance.</p><p><strong>Methods: </strong>A multicentre descriptive cross-sectional study was conducted in regular surgical and medical departments of seven selected hospitals in the Czech Republic. On the first day of hospitalization, patients completed the FIRST screening questionnaire. Their subjectively perceived sleep quality for the previous night was assessed from the second to the fourth day of hospitalization using the <i>Richards-Campbell Sleep Questionnaire</i> (RCSQ).</p><p><strong>Results: </strong>The study included 340 patients (172 females and 168 males; mean age 58.9 ± 14.9 years and 57.3 ± 15.0 years, respectively). No significant differences in RCSQ scores were observed between men and women or across the three nights of hospitalization. Moderate correlations were identified between hospitalization data and RCSQ scores, with the strongest positive correlation for alprazolam use (Ra = 0.604). Other positive correlations included surgical department hospitalization, sleep-inducing medications, surgery, male sex, and age. The strongest negative correlation was with pain (Ra = -0.498), while other negative correlations included elective admission, medical department hospitalization, and previous hospitalization. The studied factors explained 18% of the RCSQ variability. The association between FIRST scores and RCSQ was statistically significant (p < 0.001) but weak (Spearman's -0.1734, Kendall's tau -0.1234).</p><p><strong>Conclusion: </strong>Subjective sleep quality during hospitalization is related to the type of department, care provided, and pain, age, and sex. There were no significant changes in subjective sleep quality ratings during the first three days of hospitalization. The FIRST questionnaire is not a suitable screening tool for identifying individuals with situational sleep disturbance in hospital.</p>","PeriodicalId":18896,"journal":{"name":"Nature and Science of Sleep","volume":"17 ","pages":"505-515"},"PeriodicalIF":3.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11960453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring New Avenues for OSA Screening: Optimization and Future Perspectives of Nomogram for Hypertensive Patients [Letter].","authors":"Hongrun Pan, Suqiong Yang, Peikun Hong","doi":"10.2147/NSS.S526816","DOIUrl":"10.2147/NSS.S526816","url":null,"abstract":"","PeriodicalId":18896,"journal":{"name":"Nature and Science of Sleep","volume":"17 ","pages":"517-518"},"PeriodicalIF":3.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11960469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association Between School Connectedness and Sleep Health in Children and Adolescents: A Systematic Review.","authors":"Monika Raniti, Muhammad Reza Chairilsyah, Muhammad Nur Imaduddin Suma, Susan M Sawyer","doi":"10.2147/NSS.S498002","DOIUrl":"10.2147/NSS.S498002","url":null,"abstract":"<p><p>Schools are key settings for sleep health promotion and interventions. Yet their value as rich social-emotional environments that shape student health and wellbeing has largely been neglected by sleep research. School connectedness reflects students' engagement with learning and sense of belonging with peers, teachers, and the school environment. Although school connectedness is associated with physical and mental health in children and adolescents, whether it is associated with sleep is unclear. To address this gap, we systematically reviewed the evidence for cross-sectional and prospective associations between school connectedness and sleep. We searched Medline, PubMed, PsycINFO, and ERIC databases for observational and intervention studies published from 1950 to 17^th July 2024 that examined relationships between school connectedness and sleep health or sleep problems/disorders in four- to 24-year-olds. We identified ten eligible studies (seven cross-sectional and three longitudinal) for narrative synthesis. Studies were primarily from China and Taiwan (n = 6) and conducted in secondary schools (n = 8). Participants were 14.5 years old, on average. Most of the cross-sectional studies found a positive relationship between school connectedness and sleep health. All longitudinal studies reported at least one significant relationship between school connectedness and sleep health, however two of these studies also reported non-significant relationships. We did not identify any intervention studies. Most studies were rated as 'fair' quality representing a moderate risk of bias. The findings of this review suggest that school connectedness is linked to some aspects of sleep health and insomnia in secondary-school aged adolescents. Longitudinal studies are needed to explore prospective relationships in addition to studies conducted in primary and tertiary education settings.</p>","PeriodicalId":18896,"journal":{"name":"Nature and Science of Sleep","volume":"17 ","pages":"489-504"},"PeriodicalIF":3.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11952061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mendelian Randomization Analysis Identifies Causal Effects of Multi-Site Chronic Pain on Obstructive Sleep Apnea.","authors":"Zuxing Wang, Lili Chen, Ruishi Kang, Zhuowei Li, Jiangang Fan, Yi Peng, Yunqi He, Xiaolong Zhao","doi":"10.2147/NSS.S487056","DOIUrl":"10.2147/NSS.S487056","url":null,"abstract":"<p><strong>Background: </strong>Observational studies have suggested an association between obstructive sleep apnea (OSA) and chronic pain disorders, but causal evidence have not been confirmed.</p><p><strong>Methods: </strong>Here we performed Mendelian randomization (MR) study to explore the potential causal association and mediating roles of modifiable factors between multi-site chronic pain (MCP) and OSA. Independent single nucleotide polymorphisms (SNPs) (N=26) from MCP GWAS (n=387,649) in the UK Biobank were used as instrumental variables to test associations with OSA from the FinnGen consortium, which encompassed 16,761 individuals with OSA cases and 201,194 individuals without OSA.</p><p><strong>Results: </strong>MR analyses provide genetic evidence to predict MCP on the risk of OSA. Specifically, a per-site increase in multi-site chronic pain was linked to a 184% higher risk of OSA (OR_IVW = 1.84, 95% CI = 1.29-2.63, p = 7.24×10^-4). However, we also performed reverse association analyses and found no significant casual effect of OSA on MCP. MR estimates were in agreement regardless of the method used, such as MR-egger, weighted median and weighted mode, thereby demonstrating the accuracy of the causal associations. Through mediation analyses, we found that body mass index (BMI), waist circumference, and educational attainment explained a substantial proportion of the association between MCP and OSA (proportion mediated=21.13%; 26.57% and 9.66% respectively).</p><p><strong>Conclusion: </strong>Our findings suggest that both pain management interventions, prevention of obesity and health education are likely to be effective strategies to reduce OSA risk in individuals with MCP.</p>","PeriodicalId":18896,"journal":{"name":"Nature and Science of Sleep","volume":"17 ","pages":"463-473"},"PeriodicalIF":3.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11929529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Restorative Effects of Daytime Naps on Inhibitory Control: A Neuroimaging Study Following Sleep Deprivation.","authors":"Leilei Li, Ya Li, Sihang Yu, Ziliang Xu, Chen Wang, Fan Guo, Yingjuan Chang, Ran Zhang, Peng Fang, Yuanqiang Zhu","doi":"10.2147/NSS.S499702","DOIUrl":"10.2147/NSS.S499702","url":null,"abstract":"<p><strong>Background: </strong>Sleep deprivation is known to impair cognitive performance, particularly inhibitory control, which is crucial for goal-directed behavior. While extended recovery sleep is the ideal solution, the fast-paced demands of modern life often make this impractical. Brief daytime naps have emerged as a potential countermeasure, but the neural mechanisms underlying their restorative effects remain underexplored.</p><p><strong>Objective: </strong>This study aimed to investigate the effects of a 30-minute daytime nap on brain activation patterns and cognitive performance following sleep deprivation. We used task-based functional magnetic resonance imaging (fMRI) to examine how naps modulate brain regions involved in inhibitory control.</p><p><strong>Methods: </strong>Forty-five participants completed a dual-choice Oddball task under three conditions: Resting Wakefulness (RW), Sleep Deprivation (SD), and Post-Nap (Nap). Reaction times (RT), accuracy, and brain activation patterns were measured and analyzed across these states. Task-related brain activation was examined using fMRI, focusing on regions involved in the frontoparietal and default mode networks (DMN).</p><p><strong>Results: </strong>Sleep deprivation significantly impaired inhibitory control, as reflected by slower RTs and reduced accuracy. A 30-minute nap partially restored cognitive performance, with RTs and accuracy showing intermediate improvement between RW and SD. Neuroimaging data revealed that the nap restored positive activation in the prefrontal cortex, occipital lobes, and middle frontal regions, which had been significantly reduced during SD. Furthermore, the nap enhanced negative activation in the middle temporal gyrus and cingulate gyrus, regions associated with the DMN, reducing cognitive interference from irrelevant stimuli.</p><p><strong>Conclusion: </strong>Daytime naps significantly mitigate the cognitive deficits induced by SD through two primary mechanisms: (1) enhancing positive activation in task-relevant brain regions and (2) increasing negative activation in areas involved in the DMN. These findings provide novel insights into the neural basis of nap-induced cognitive recovery, underscoring the value of naps as an effective intervention to restore inhibitory control following SD.</p>","PeriodicalId":18896,"journal":{"name":"Nature and Science of Sleep","volume":"17 ","pages":"475-487"},"PeriodicalIF":3.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11929420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Central Sleep Apnea and Left Atrial Enlargement in Snoring Patients with Preserved Ejection Fraction.","authors":"Xinghe Sun, Yang Wang, Chaoqun Wu, Yinghui Gao","doi":"10.2147/NSS.S500562","DOIUrl":"10.2147/NSS.S500562","url":null,"abstract":"<p><strong>Background: </strong>Central sleep apnea (CSA) significantly impacts cardiovascular health, linking it to left atrial enlargement, atrial fibrillation, and impaired cardiac function in heart failure patients with reduced ejection fraction (EF). However, the relationship between CSA and left atrial size in individuals with preserved EF remains underexplored.</p><p><strong>Objective: </strong>This study aims to examine the relationship between left atrial size and CSA in snoring patients with preserved EF.</p><p><strong>Methods: </strong>An observational study was conducted involving 341 consecutive snoring patients from a cardiology department who underwent overnight polysomnography (PSG) and echocardiography. Patients with EF below 50%, pulmonary diseases or neuromuscular disorders were excluded. CSA was defined as a central apnea-hypopnea index (CAHI) of five or more events per hour. Inverse probability of treatment weighting (IPTW) and logistic regression models were employed to evaluate the relationship between CSA and left atrial size.</p><p><strong>Results: </strong>Among the 341 patients, 33 (9.68%) were diagnosed with CSA, with a higher prevalence in males (10.0%) than females (8.91%). Left atrial enlargement (LAE) was observed in 172 patients (50.44%), predominantly in females (71.29%). CSA patients demonstrated significantly higher apnea-hypopnea index (AHI) (49.2/h vs 26.75/h, p < 0.01) and oxygen desaturation index (ODI) (44.9 vs 22.85, p < 0.01), alongside more sleep time with oxygen saturation < 90% (6.6% vs 2.35%, p = 0.01). Echocardiographic evaluations revealed that CSA patients had a greater left atrial anterior-posterior diameter(LAD-ap 42.73 ± 13.01 mm vs 38.15 ± 4.58 mm, p < 0.01) and a higher frequency of LAE (69.7% vs 48.38%, p = 0.02). Males with CSA had a significantly increased risk of LAE (OR: 4.54; 95% CI: 1.45-14.2) after IPTW adjustment, with significant associations persisting among those with risk factors such as smoking and dyslipidemia.</p><p><strong>Conclusion: </strong>This study highlights a significant association between CSA and left atrial enlargement in males with preserved EF, suggesting that CSA may contribute to atrial remodeling even without reduced ejection fraction.</p>","PeriodicalId":18896,"journal":{"name":"Nature and Science of Sleep","volume":"17 ","pages":"447-460"},"PeriodicalIF":3.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing the Robustness of MR Analysis on OSA and Migraine: Addressing Key Limitations [Letter].","authors":"Xin Wu, Lizhu Liang, Zheng Wei","doi":"10.2147/NSS.S523816","DOIUrl":"10.2147/NSS.S523816","url":null,"abstract":"","PeriodicalId":18896,"journal":{"name":"Nature and Science of Sleep","volume":"17 ","pages":"461-462"},"PeriodicalIF":3.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Brain to Insomnia: Can Neurotrophic Factors Unlock the Sleep Puzzle After Stroke? [Letter].","authors":"Suqiong Yang, Hongrun Pan, Peikun Hong","doi":"10.2147/NSS.S524829","DOIUrl":"10.2147/NSS.S524829","url":null,"abstract":"","PeriodicalId":18896,"journal":{"name":"Nature and Science of Sleep","volume":"17 ","pages":"435-436"},"PeriodicalIF":3.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}