Nanoscale Advances最新文献_第6页

Emerging engineered nanozymes: current status and future perspectives in cancer treatments

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-28 DOI: 10.1039/D4NA00924J

Jiajia Zheng, Weili Peng, Houhui Shi, Jiaqi Zhang, Qinglian Hu and Jun Chen

{"title":"Emerging engineered nanozymes: current status and future perspectives in cancer treatments","authors":"Jiajia Zheng, Weili Peng, Houhui Shi, Jiaqi Zhang, Qinglian Hu and Jun Chen","doi":"10.1039/D4NA00924J","DOIUrl":"10.1039/D4NA00924J","url":null,"abstract":"Composite nanozymes are composed of enzymes with similar or different catalytic capabilities and have higher catalytic activity than a single enzyme. In recent years, composite nanozymes have emerged as novel nanomaterial platforms for multiple applications in various research fields, where they are used to produce oxygen, consume glutathione, or produce toxic reactive oxygen species (ROS) for cancer therapy. The therapeutic approach using composite nanozymes is known as chemo-dynamic therapy (CDT). Some composite nanozymes also show special photothermal conversion effects, enabling them to be combined with pioneering cancer treatments, such as photodynamic therapy (PDT), photothermal therapy (PTT) and sonodynamic therapy (SDT), and enhance the anti-cancer effects. In this study, the classification and catalytic performances of composite nanozymes are reviewed, along with their advantages and synthesis methods. Furthermore, the applications of composite nanozymes in the treatment of cancers are emphasized, and the prospective challenges in the future are discussed.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" 5","pages":" 1226-1242"},"PeriodicalIF":4.6,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11774201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Construction of an MXene/MIL Fe-53/ZIF-67 derived bifunctional electrocatalyst for efficient overall water splitting.

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-27 DOI: 10.1039/d4na00936c

Komal Farooq, Maida Murtaza, Laraib Kiran, Kashf Farooq, Waqas Ali Shah, Amir Waseem

{"title":"Construction of an MXene/MIL Fe-53/ZIF-67 derived bifunctional electrocatalyst for efficient overall water splitting.","authors":"Komal Farooq, Maida Murtaza, Laraib Kiran, Kashf Farooq, Waqas Ali Shah, Amir Waseem","doi":"10.1039/d4na00936c","DOIUrl":"10.1039/d4na00936c","url":null,"abstract":"Research on water splitting is paramount for developing low-carbon alternative energy sources. Nevertheless, creating an efficient, cost-effective, and bifunctional electrocatalyst that facilitates both the oxygen evolution reaction (OER) and the hydrogen evolution reaction (HER) remains an elusive goal. In this work, we report a novel hybrid nanostructured electrocatalyst by combining and pyrolyzing MXene, MIL-53(Fe), and ZIF-67. Comprehensive characterization of the synthesized nanocomposites was conducted using XRD, FESEM, TEM, EDX, and XPS. Notably, among the synthesized electrocatalysts, M3 demonstrated exceptional performance, achieving 10 mA cm-2 at 237 mV and 50 mA cm-2 at 292 mV for the OER, and 10 mA cm-2 at 307 mV and 50 mA cm-2 at 481 mV for the HER. The Tafel slope values were 64 mV dec-1 for the OER and 185 mV dec-1 for the HER at 10 mA cm-2. Moreover, M3 exhibited excellent stability, with negligible current density loss over 12 hours, and showed good mass activity of 57.5 and 54.6 A g-1 and TOFs of 1.56 and 2.97 s-1, for the OER and HER, respectively. This study highlights the efficacy of integrating MXene (Ti3C2T x ) with MIL-53(Fe) and ZIF-67, creating a potent bifunctional OER and HER electrocatalyst. The synergistic combination enhances electrical conductivity, active site availability, and structural stability, yielding superior performance. The findings of this investigation underscore the importance of strategic design and optimization of bifunctional electrocatalysts for energy conversion applications.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A multistimuli responsive and self-healing Zn(ii)-inosine supramolecular metal-organic gel: phase selective gelation and application as a light-responsive Schottky barrier diode.

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-25 DOI: 10.1039/d4na01079e

Surbhi Singh, Atul Kumar Sharma, Kunal Rohilla, Nisha Verma, Bhagwati Sharma

{"title":"A multistimuli responsive and self-healing Zn(ii)-inosine supramolecular metal-organic gel: phase selective gelation and application as a light-responsive Schottky barrier diode.","authors":"Surbhi Singh, Atul Kumar Sharma, Kunal Rohilla, Nisha Verma, Bhagwati Sharma","doi":"10.1039/d4na01079e","DOIUrl":"10.1039/d4na01079e","url":null,"abstract":"Utilization of naturally available biomolecules such as nucleosides with several coordination sites as organic counterparts for the synthesis of multifunctional self-assembled metal-organic gels is important, considering the time and efforts required for the design of organic ligands that can coordinate to metal ions, forming a gel. In the present work, inosine, a simple nucleoside has been utilized as a ligand for the generation of a supramolecular metallo-hydrogel through coordination with Zn2+ ions in the presence of NaOH. Several spectroscopic, microscopic and rheological investigations have been performed to characterize the formed gel. The obtained metallo-hydrogel is transparent, and the transparency can be tuned depending on the amount of NaOH used. The Zn-inosine metal-organic gel exhibits several functional properties such as self-healing, stimuli responsiveness, thixotropy, and injectability. Furthermore, the freeze-dried Zn-inosine xerogel exhibited selective gelation of water, which has been utilized to separate water from mixtures that include organic solvents (or oils) and water. The semiconducting characteristics of the Zn-inosine metallogel have been used for device fabrication based on the Schottky diode interface between a semiconductor and metal. The fabricated device was found to be photo-responsive in nature and exhibited better device parameters when illuminated with light. The present results are anticipated to lead to the development of newer soft materials constructed using simple biomolecules for environmental and electronic applications.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication of water-dispersible dye/polymer matrix-stabilized β-FeOOH (Rh-B/F127@β-FeOOH) nanoparticles: synthesis, characterization and therapeutic applications.

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-24 DOI: 10.1039/d4na00595c

Neela Mohan Chidambaram, Palanisamy Rajkumar, P Arul Prakash, G M Rathika, K Prabhu, Senthil Muthu Kumar Thiagamani, M Khalid Hossain, Manikandan Ayyar, Lalitha Gnanasekaran, Jinho Kim

{"title":"Fabrication of water-dispersible dye/polymer matrix-stabilized β-FeOOH (Rh-B/F127@β-FeOOH) nanoparticles: synthesis, characterization and therapeutic applications.","authors":"Neela Mohan Chidambaram, Palanisamy Rajkumar, P Arul Prakash, G M Rathika, K Prabhu, Senthil Muthu Kumar Thiagamani, M Khalid Hossain, Manikandan Ayyar, Lalitha Gnanasekaran, Jinho Kim","doi":"10.1039/d4na00595c","DOIUrl":"10.1039/d4na00595c","url":null,"abstract":"In this study, dye/polymer matrix-stabilized β-FeOOH nanomaterials were fabricated for therapeutic applications. Rh-B/F127@β-FeOOH nanomaterials were synthesized using two different methods: co-precipitation (CoP) and hydrothermal (HT) methods. The as-synthesized nanoparticles were characterized using various spectroscopic techniques, including FT-IR, UV-Vis, PL, XRD, HR-TEM, and XPS analysis. The functional groups and optical properties were confirmed by FT-IR spectroscopy, UV-Vis and fluorescence spectroscopy. The Rh-B/F127@β-FeOOH nanomaterials exhibited both rod-like and sphere-like morphology, as confirmed by HR-TEM analysis. Unlike the nanorods, the nanospheres produced multi-colored emissions at 407, 446, 482 and 520 nm. The oxidative states and elements were confirmed by XPS spectroscopy. MTT assays were used to analyze the cytotoxicity of the nanospheres against A549 cells. The reactive oxygen species (ROS) generation and apoptotic cell death caused by the β-FeOOH nanospheres were evaluated by flow cytometry. Cell cycle analysis indicated that the treatment of nanospheres-induced S-phase cell cycle arrest in A549 cells. The synthesized nanospheres induced late-stage apoptosis in the A549 cell line, with a cell death rate of up to 30.37% at the IC50 concentration. Additionally, the antioxidant activities of the synthesized nanorods showed a high scavenging activity against free radicals, as examined by different assays such as such as DPPH, RP, and FRAP. The above results suggest that the synthesized nanorods and nanospheres are promising and efficient material for therapeutic applications.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insights into the electronic structure, optical properties, and photocatalytic potential of Gd₂CoCrO₆ perovskite: a comprehensive theoretical and experimental investigation.

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-23 DOI: 10.1039/d4na01033g

M J Hosen, M Tarek, M D I Bhuyan, M A Basith, I M Syed

{"title":"Insights into the electronic structure, optical properties, and photocatalytic potential of Gd2CoCrO6 perovskite: a comprehensive theoretical and experimental investigation.","authors":"M J Hosen, M Tarek, M D I Bhuyan, M A Basith, I M Syed","doi":"10.1039/d4na01033g","DOIUrl":"10.1039/d4na01033g","url":null,"abstract":"In this study, we present a comprehensive theoretical and experimental investigation into the electronic structure, optical properties, and photocatalytic potential of Gd2CoCrO6 (GCCO) double perovskite. Using first-principles calculations with the generalized-gradient-approximation plus Hubbard U (GGA + U) method, we explored the effects of Coulomb interactions on the electronic properties. Our calculations revealed that GCCO exhibits a half-metallic nature, displaying metallic behavior for up-spin and semiconducting behavior for down-spin states. The optimized U eff value of 4.2 eV accurately reproduces the direct bandgap of 2.25 eV, which aligns closely with experimental results obtained through UV-visible absorption spectroscopy and photoluminescence analysis. Additionally, time-resolved photoluminescence (TRPL) measurements indicate a mean charge carrier lifetime of 2.37 ns, suggesting effective charge separation. Mott-Schottky analysis and valence band X-ray photoelectron spectroscopy (XPS) confirm the n-type semiconducting nature of GCCO with favorable band edge positions for redox reactions. The combination of theoretical insights and experimental characterization indicates that GCCO holds significant promise as a photocatalyst for applications in renewable energy production and environmental remediation, particularly in solar-driven water splitting and pollutant degradation. Our study provides crucial insights into the electronic structure and optical properties of double perovskites like GCCO, highlighting their suitability for photocatalytic applications. Furthermore, the research paves the way for future work in the compositional engineering and defect modulation of double perovskites to optimize their photocatalytic efficiency.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

X-ray photoelectron spectroscopy of metal oxide nanoparticles: chemical composition, oxidation state and functional group content.

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-23 DOI: 10.1039/d4na00943f

Gregory P Lopinski, Oltion Kodra, Filip Kunc, David C Kennedy, Martin Couillard, Linda J Johnston

{"title":"X-ray photoelectron spectroscopy of metal oxide nanoparticles: chemical composition, oxidation state and functional group content.","authors":"Gregory P Lopinski, Oltion Kodra, Filip Kunc, David C Kennedy, Martin Couillard, Linda J Johnston","doi":"10.1039/d4na00943f","DOIUrl":"10.1039/d4na00943f","url":null,"abstract":"Surface chemistry drives the interaction of a material with its surroundings, therefore it can be used to understand and influence the fate of nanomaterials when used as functional materials or when released to the environment. Here we have used X-ray photoelectron spectroscopy (XPS) to probe the chemical composition, oxidation state and functional group content of the near surface region of four families of commercially available metal oxide nanoparticles from several different suppliers. The analyzed nanoparticles varied in size and surface functionalization (unfunctionalized vs. amine, stearic acid, and PVP-coated samples). Survey and high-resolution scans have provided information on the atomic composition of the samples, including an estimate of the stoichiometry of the metal oxide, the presence of functional groups and the identification and quantification of any impurities on the surface. The presence of significant impurities for some samples and the variation from the expected oxidation state in other cases are relevant to studies of the environmental and health impacts of these materials as well as their use in applications. The functional group content measured by XPS shows a similar trend to earlier quantitative nuclear magnetic resonance (qNMR) data for aminated samples. This indicates that XPS can be a complementary probe of surface functional group content in cases where the functional group contains a unique element not otherwise present on the nanoparticles.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Band structure and magnetism engineering of InSe monolayers through doping with IVA- and VA-group atoms: role of impurities 通过掺杂 IVA 和 VA 族原子实现硒化铟单层的带状结构和磁性工程：杂质的作用。

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-23 DOI: 10.1039/D4NA01013B

Nguyen Thi Han, J. Guerrero-Sanchez and D. M. Hoat

{"title":"Band structure and magnetism engineering of InSe monolayers through doping with IVA- and VA-group atoms: role of impurities","authors":"Nguyen Thi Han, J. Guerrero-Sanchez and D. M. Hoat","doi":"10.1039/D4NA01013B","DOIUrl":"10.1039/D4NA01013B","url":null,"abstract":"In this work, we investigate the electronic and magnetic properties of the InSe monolayer enriched by doping with IVA-group (Si and Ge) and VA-group (P and As) atoms. Both In and Se sublattices are considered as doping sites to realize n- and p-type doping (XIn@InSe and XSe@InSe systems, X = Si, Ge, P, and As), respectively. The pristine InSe monolayer is an indirect gap semiconductor with a band gap of 1.41 eV. n-Doping processes preserve the monolayer's nonmagnetic nature. IVA-group impurities lead to monolayer metallization, while a considerable band gap reduction is induced by doping with VA-group atoms. The band gap also decreases considerably when realizing p-type doping with IVA-group atoms. In contrast, monolayer magnetization is achieved by p-type doping when replacing Se atoms with P and As atoms, leading to the formation of new 2D magnetic semiconductors. In these cases, VA-group impurities mainly produce the system's magnetism. Furthermore, our calculations also provide evidence for the emergence of magnetism in the InSe monolayer through doping with pair impurities (pX@InSe systems), where Si2/Ge2 (incorporated at the Se sublattice) and P1/As1 (incorporated at the In sublattice) dopant atoms play a key role in determining the electronic and magnetic properties of respective pair-atom-doped systems. Herein, the magnetic semiconductor nature of pSi@InSe and pGe@InSe systems is confirmed, while pAs@InSe is found to be a half-metallic system. Our results suggest the usefulness of doping with IVA- and VA-group atoms that can serve as an effective strategy to functionalize the InSe monolayer, providing insights into the role of impurities.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" 5","pages":" 1443-1451"},"PeriodicalIF":4.6,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11756556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modelling VA-CNT surface morphology for pollutant adsorption from aqueous media.

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-22 DOI: 10.1039/d4na00915k

Inês E Oliveira, Ricardo M Silva, Cláudia G Silva, Rui F Silva

{"title":"Modelling VA-CNT surface morphology for pollutant adsorption from aqueous media.","authors":"Inês E Oliveira, Ricardo M Silva, Cláudia G Silva, Rui F Silva","doi":"10.1039/d4na00915k","DOIUrl":"10.1039/d4na00915k","url":null,"abstract":"The absorption of organic dyes from aqueous medium by vertically aligned carbon nanotubes (VA-CNTs) is an ongoing research topic, as these nanostructures present outstanding physical and chemical properties that may favor their interaction with organic pollutants. The growth temperature variation yields different VA-CNT surface morphologies ranging from wave-like patterns to patternless or planar patterns. Here, we demonstrate the effect of the interaction between the intrinsic oxygen concentration of the VA-CNTs grown at different temperatures (650 °C and 700 °C) on the adsorption of cationic (Rhodamine B - RhB) and anionic (Methyl Orange - MO) dyes from aqueous media through UV-vis spectrophotometry studies. The XPS technique was applied to estimate the oxygen percentage (O at%) present on the nanotubes as follows: 0.62% on the wavy patterned VA-CNTs and 2.32% on VA-CNTs without a pattern. The highest adsorption performance was accomplished by VA-CNTs without a pattern for RhB dye, attributed to electrostatic interactions, where the positively charged RhB is attracted to the negatively charged nanotube surface. In this way, VA-CNTs have shown adsorption characteristics crucial for wastewater decontamination.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11788671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gum Arabic induced assembly of cellulose nanocrystals in aqueous media.

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-22 DOI: 10.1039/d4na00981a

David Attia, Yael Levi-Kalisman, Ronit Bitton, Rachel Yerushalmi-Rozen

{"title":"Gum Arabic induced assembly of cellulose nanocrystals in aqueous media.","authors":"David Attia, Yael Levi-Kalisman, Ronit Bitton, Rachel Yerushalmi-Rozen","doi":"10.1039/d4na00981a","DOIUrl":"10.1039/d4na00981a","url":null,"abstract":"Entropy-driven assembly of nematic liquid-crystal phases of cellulose nanocrystals (SCNCs) in aqueous suspensions results in the emergence of a cholesteric liquid crystalline phase (N* phase). We report that a solvated, non-adsorbing, highly branched natural polysaccharide, Gum Arabic (GA), strongly affects the assembly of the SCNCs and modifies the phase diagram: GA leads to significant crowding of the SCNC rods and induces a new liquid-liquid phase transition, where SCNC-rich and GA-rich droplets coexist. The solvated GA does not induce coagulation or gelation of the suspended SCNCs (at low concentrations of 1-3 wt% of GA). In the SCNC-rich droplets, finite-sized nematic nano-islands assemble and further evolve into cholesteric tactoids and nucleate the formation of the N* phase at significantly lower concentration (about 1.5 wt%) than in GA-free suspensions. We observe that the inter-particle distance and the chiral pitch of the N* phase are determined by the concentration of GA (for a given SCNC concentration). The resulting mesophases are characterized via transmission electron microscopy at cryogenic temperatures (cryo-TEM), small-angle X-ray scattering (SAXS), and polarized optical microscopy (POM). Our findings indicate that GA can be used to tune the phase diagram and optical properties of SCNC suspensions, and overcome kinetic barriers that lead to gelation or kinetic arrest.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11775582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

pH-Sensitive oligopeptide magnetic mesoporous silica beads for deoxyribonucleic acid extraction.

IF 4.6 3区材料科学

Nanoscale Advances Pub Date : 2025-01-21 DOI: 10.1039/d4na00987h

Sihua Qian, Yiting Wang, Junjie Fan, Tong Kong, Yuhui Wang, Kaizhe Wang, Yufeng Liao, Li Wang, Jianping Zheng

{"title":"pH-Sensitive oligopeptide magnetic mesoporous silica beads for deoxyribonucleic acid extraction.","authors":"Sihua Qian, Yiting Wang, Junjie Fan, Tong Kong, Yuhui Wang, Kaizhe Wang, Yufeng Liao, Li Wang, Jianping Zheng","doi":"10.1039/d4na00987h","DOIUrl":"10.1039/d4na00987h","url":null,"abstract":"Exploring novel synthesis strategies for magnetic beads to extract nucleic acids is of great significance in the field of in vitro diagnostics. In the present research, monodisperse magnetic mesoporous silica beads were synthesized via the thermolysis reaction of Fe(acac)3 by using large-pore dendritic silica colloids as templates, and were further functionalized with a highly pH-sensitive histidine-glutamate co-oligopeptide for deoxyribonucleic acid extraction. The large-pore dendritic silica colloid scaffolds were utilized for high-density incorporation of superparamagnetic iron oxide nanoparticles within the vertical channels. The morphology and properties of the as-prepared pH-sensitive oligopeptide magnetic mesoporous silica beads were evaluated by transmission electron microscopy, scanning electron microscopy, vibrating sample magnetometry, X-ray photoelectron spectroscopy, X-ray diffraction testing and so on. The average size of the obtained magnetic beads was 370 nm in diameter with a narrow size distribution. The saturation magnetization and magnetic content of the resultant magnetic beads were 25 emu g-1 and 59%, respectively. Moreover, the magnetic mesoporous silica beads exhibited an obvious pH-responsive behavior. Due to these remarkable features, successful deoxyribonucleic acid capture using the as-prepared pH-sensitive oligopeptide magnetic mesoporous silica beads was achieved.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0