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Molecular & Cellular Toxicology最新文献

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MiR-192-5p protects hexavalent chromium-induced apoptosis in renal epithelial cells by inhibiting p53 signaling pathway MiR-192-5p通过抑制p53信号通路保护六价铬诱导的肾上皮细胞凋亡
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-06-23 DOI: 10.1007/s13273-025-00555-w
Leying Wen, Kai Cai, Caixia Fan, Lifang Jin, Guoquan Fu, Junyan Yan
{"title":"MiR-192-5p protects hexavalent chromium-induced apoptosis in renal epithelial cells by inhibiting p53 signaling pathway","authors":"Leying Wen, Kai Cai, Caixia Fan, Lifang Jin, Guoquan Fu, Junyan Yan","doi":"10.1007/s13273-025-00555-w","DOIUrl":"https://doi.org/10.1007/s13273-025-00555-w","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"22 1","pages":"57-66"},"PeriodicalIF":0.0,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147921090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Parthenolide attenuates cognitive impairment following cerebral ischemia–reperfusion injury by inhibiting the intestinal NF-κB signaling pathway and maintaining gut homeostasis Parthenolide通过抑制肠道NF-κB信号通路和维持肠道稳态来减轻脑缺血再灌注损伤后的认知功能障碍
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-05-15 DOI: 10.1007/s13273-025-00546-x
Yun Zhang, JiaYi Huang, Shiqing Gao, Ling Lin, YongBing Zheng
{"title":"Parthenolide attenuates cognitive impairment following cerebral ischemia–reperfusion injury by inhibiting the intestinal NF-κB signaling pathway and maintaining gut homeostasis","authors":"Yun Zhang, JiaYi Huang, Shiqing Gao, Ling Lin, YongBing Zheng","doi":"10.1007/s13273-025-00546-x","DOIUrl":"https://doi.org/10.1007/s13273-025-00546-x","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"21 6","pages":"1345-1357"},"PeriodicalIF":0.0,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147922800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stigmasterol protects H9c2 cells from angiotensin-II induced hypertrophy by regulating apoptosis and autophagy 豆甾醇通过调节细胞凋亡和自噬来保护H9c2细胞免受血管紧张素ii诱导的肥大
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-05-13 DOI: 10.1007/s13273-025-00543-0
Mingming Chang, Jinjin Meng, Ge Liu, Chao Shi
{"title":"Stigmasterol protects H9c2 cells from angiotensin-II induced hypertrophy by regulating apoptosis and autophagy","authors":"Mingming Chang, Jinjin Meng, Ge Liu, Chao Shi","doi":"10.1007/s13273-025-00543-0","DOIUrl":"https://doi.org/10.1007/s13273-025-00543-0","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"21 6","pages":"1323-1332"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147906705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histone methyltransferase DOT1L promotes myeloid-derived suppressor cell activation to ameliorate colitis by modulating JAK2/STAT3 signaling 组蛋白甲基转移酶DOT1L通过调节JAK2/STAT3信号通路，促进髓源性抑制细胞活化，改善结肠炎
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-05-13 DOI: 10.1007/s13273-025-00544-z
Feng Dong, LiJia Shao, Rui Gong, LiHong Shen, LiMin Wang
{"title":"Histone methyltransferase DOT1L promotes myeloid-derived suppressor cell activation to ameliorate colitis by modulating JAK2/STAT3 signaling","authors":"Feng Dong, LiJia Shao, Rui Gong, LiHong Shen, LiMin Wang","doi":"10.1007/s13273-025-00544-z","DOIUrl":"https://doi.org/10.1007/s13273-025-00544-z","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"21 6","pages":"1333-1344"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147919479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Shubu Wenshen Guchang alleviates intestinal barrier and inflammatory damage in irinotecan-induced delayed diarrhea via regulating gut microbiota and JNK signal pathway 舒补文参固肠通过调节肠道菌群和JNK信号通路，减轻伊立替康致迟发性腹泻的肠道屏障和炎症损伤
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-05-07 DOI: 10.1007/s13273-025-00538-x
Qiong Zhang, Zonglang Lai, Weiqi Nian, Huaibi Wang, Jin Tao
{"title":"Shubu Wenshen Guchang alleviates intestinal barrier and inflammatory damage in irinotecan-induced delayed diarrhea via regulating gut microbiota and JNK signal pathway","authors":"Qiong Zhang, Zonglang Lai, Weiqi Nian, Huaibi Wang, Jin Tao","doi":"10.1007/s13273-025-00538-x","DOIUrl":"https://doi.org/10.1007/s13273-025-00538-x","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"21 6","pages":"1287-1297"},"PeriodicalIF":0.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147918663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morinda officinalis polysaccharide exerts anti-Parkinson’s disease effect via inhibiting NLRP3 inflammasome and improving pyroptosis of dopaminergic neurons 巴桑多糖通过抑制NLRP3炎性体和改善多巴胺能神经元焦亡发挥抗帕金森病作用
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-05-06 DOI: 10.1007/s13273-025-00541-2
Yanhong Dong, F Wang, Mingji Jin
{"title":"Morinda officinalis polysaccharide exerts anti-Parkinson’s disease effect via inhibiting NLRP3 inflammasome and improving pyroptosis of dopaminergic neurons","authors":"Yanhong Dong, F Wang, Mingji Jin","doi":"10.1007/s13273-025-00541-2","DOIUrl":"https://doi.org/10.1007/s13273-025-00541-2","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"21 6","pages":"1307-1322"},"PeriodicalIF":0.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147922999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
USP7 contributes to cisplatin resistance in non-small cell lung cancer by deubiquitination of BCL2 USP7通过BCL2的去泛素化参与非小细胞肺癌的顺铂耐药
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-04-09 DOI: 10.1007/s13273-025-00535-0
Zhihao Chen, Wenjun Shang, Gang Huang, Junjie Ying, Ke Shi, Dongxiao Ding, Li Wang, Chong Zhang, Yizheng Tan
{"title":"USP7 contributes to cisplatin resistance in non-small cell lung cancer by deubiquitination of BCL2","authors":"Zhihao Chen, Wenjun Shang, Gang Huang, Junjie Ying, Ke Shi, Dongxiao Ding, Li Wang, Chong Zhang, Yizheng Tan","doi":"10.1007/s13273-025-00535-0","DOIUrl":"https://doi.org/10.1007/s13273-025-00535-0","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"21 6","pages":"1265-1276"},"PeriodicalIF":0.0,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147880550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypoxia-induced USP22 contributes to tumor stemness and chemoresistance in nasopharyngeal carcinoma via stabilizing HIF-1α 缺氧诱导的USP22通过稳定HIF-1α参与鼻咽癌的肿瘤干性和化疗耐药
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-04-09 DOI: 10.1007/s13273-025-00532-3
Ke Chen, Shunxin Li
{"title":"Hypoxia-induced USP22 contributes to tumor stemness and chemoresistance in nasopharyngeal carcinoma via stabilizing HIF-1α","authors":"Ke Chen, Shunxin Li","doi":"10.1007/s13273-025-00532-3","DOIUrl":"https://doi.org/10.1007/s13273-025-00532-3","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"21 6","pages":"1239-1251"},"PeriodicalIF":0.0,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147898131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Capparis spinosa inhibits proliferation and fibrosis of myofibroblasts in systemic sclerosis through modulation of MAPK signaling 通过调节MAPK信号传导抑制系统性硬化症中肌成纤维细胞的增殖和纤维化
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-04-03 DOI: 10.1007/s13273-025-00533-2
Xiaolan Qi, Fei Fei Lou, Feng Sun, Ning Zhao, Jia Sun, Ai Shen, C. Liu
{"title":"Capparis spinosa inhibits proliferation and fibrosis of myofibroblasts in systemic sclerosis through modulation of MAPK signaling","authors":"Xiaolan Qi, Fei Fei Lou, Feng Sun, Ning Zhao, Jia Sun, Ai Shen, C. Liu","doi":"10.1007/s13273-025-00533-2","DOIUrl":"https://doi.org/10.1007/s13273-025-00533-2","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"21 6","pages":"1227-1237"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147914081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Dexmedetomidine repairs behavioral deficits through miR-365a-3p/G3BP2 axis and Nrf2/Keap1 signaling pathway in traumatic brain injury 右美托咪定通过miR-365a-3p/G3BP2轴和Nrf2/Keap1信号通路修复外伤性脑损伤的行为缺陷
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-03-18 DOI: 10.1007/s13273-025-00526-1
Peipei Kang, YuanLi Gao, JuYan Zheng, JiaQin Chen, Z L Li, GuJun Cong
{"title":"Dexmedetomidine repairs behavioral deficits through miR-365a-3p/G3BP2 axis and Nrf2/Keap1 signaling pathway in traumatic brain injury","authors":"Peipei Kang, YuanLi Gao, JuYan Zheng, JiaQin Chen, Z L Li, GuJun Cong","doi":"10.1007/s13273-025-00526-1","DOIUrl":"https://doi.org/10.1007/s13273-025-00526-1","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"21 6","pages":"1201-1213"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147922412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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