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Molecular & Cellular Toxicology最新文献

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Protective role and mechanism of sonic hedgehog signaling pathway in spinal cord injury 超音刺猬信号通路在脊髓损伤中的保护作用及机制
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-10-23 DOI: 10.1007/s13273-025-00582-7
Li Li Yin, Xiao Zhen Ji, Min Tang, Li Hui Chen, Jiu Zhou Lin, Ya Ling Jin, Wei Ting Chen
{"title":"Protective role and mechanism of sonic hedgehog signaling pathway in spinal cord injury","authors":"Li Li Yin, Xiao Zhen Ji, Min Tang, Li Hui Chen, Jiu Zhou Lin, Ya Ling Jin, Wei Ting Chen","doi":"10.1007/s13273-025-00582-7","DOIUrl":"https://doi.org/10.1007/s13273-025-00582-7","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"22 2","pages":"339-350"},"PeriodicalIF":0.0,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147916880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antiplatelet activity of Alisma orientale extract through inhibiting glycoprotein VI and its downstream signaling pathways 泽泻提取物通过抑制糖蛋白VI及其下游信号通路的抗血小板活性
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-10-19 DOI: 10.1007/s13273-025-00575-6
Yeon‐Ji Kim, Tae In Kim, Hado Choi, Kyungho Kim
{"title":"Antiplatelet activity of Alisma orientale extract through inhibiting glycoprotein VI and its downstream signaling pathways","authors":"Yeon‐Ji Kim, Tae In Kim, Hado Choi, Kyungho Kim","doi":"10.1007/s13273-025-00575-6","DOIUrl":"https://doi.org/10.1007/s13273-025-00575-6","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"22 1","pages":"217-227"},"PeriodicalIF":0.0,"publicationDate":"2025-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147879549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
GPR1 ameliorates intermittent hypoxia-induced neuroinflammation in a mouse model of obstructive sleep apnea by regulating TAFA1-mediated ferroptosis GPR1通过调节tafa1介导的铁上吊，改善阻塞性睡眠呼吸暂停小鼠模型中间歇性缺氧诱导的神经炎症
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-10-15 DOI: 10.1007/s13273-025-00569-4
Miao‐Shang Su, Xinglei Su, ShiNi Dong, Qiuling Huang, Chaopeng Liu, ManHuan Xu
{"title":"GPR1 ameliorates intermittent hypoxia-induced neuroinflammation in a mouse model of obstructive sleep apnea by regulating TAFA1-mediated ferroptosis","authors":"Miao‐Shang Su, Xinglei Su, ShiNi Dong, Qiuling Huang, Chaopeng Liu, ManHuan Xu","doi":"10.1007/s13273-025-00569-4","DOIUrl":"https://doi.org/10.1007/s13273-025-00569-4","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"22 1","pages":"191-202"},"PeriodicalIF":0.0,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147922995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
UBE2N is associated with gastric cancer progression: inhibiting apoptosis and ferroptosis by mediating p53 degradation UBE2N与胃癌进展相关：通过介导p53降解抑制细胞凋亡和铁下垂
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-09-27 DOI: 10.1007/s13273-025-00573-8
Chai Hua, Shuang Jiang, Yanfeng Li, Jingjing Qian, Zhiyong Shen
{"title":"UBE2N is associated with gastric cancer progression: inhibiting apoptosis and ferroptosis by mediating p53 degradation","authors":"Chai Hua, Shuang Jiang, Yanfeng Li, Jingjing Qian, Zhiyong Shen","doi":"10.1007/s13273-025-00573-8","DOIUrl":"https://doi.org/10.1007/s13273-025-00573-8","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"22 1","pages":"203-215"},"PeriodicalIF":0.0,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147898552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Helicobacter pylori CagA protein confers aggressive phenotypes to gastric cancer cells through the HIF-1α-mediated metabolic reprogramming 幽门螺杆菌CagA蛋白通过hif -1α介导的代谢重编程赋予胃癌细胞侵袭性表型
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-09-25 DOI: 10.1007/s13273-025-00577-4
S. Li, Xuehong Wang
{"title":"Helicobacter pylori CagA protein confers aggressive phenotypes to gastric cancer cells through the HIF-1α-mediated metabolic reprogramming","authors":"S. Li, Xuehong Wang","doi":"10.1007/s13273-025-00577-4","DOIUrl":"https://doi.org/10.1007/s13273-025-00577-4","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"22 2","pages":"263-275"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147911509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sulforaphane ameliorates endometriosis in rats by modulating autophagy and mitochondrial dysfunction 萝卜硫素通过调节自噬和线粒体功能障碍改善大鼠子宫内膜异位症
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-09-10 DOI: 10.1007/s13273-025-00570-x
Danmei Pang, MouChang Qiu, Feifei Xu
{"title":"Sulforaphane ameliorates endometriosis in rats by modulating autophagy and mitochondrial dysfunction","authors":"Danmei Pang, MouChang Qiu, Feifei Xu","doi":"10.1007/s13273-025-00570-x","DOIUrl":"https://doi.org/10.1007/s13273-025-00570-x","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147894198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study on eEF1A2’s mechanism in ameliorating the myocardial injury in ischemic cardiomyopathy via the AMPK/NF-κB signal pathway eEF1A2通过AMPK/NF-κB信号通路改善缺血性心肌病心肌损伤的机制研究
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-08-27 DOI: 10.1007/s13273-025-00565-8
Zhi Xing, Shajidan Abudureyimu, Palida Abulaiti, Yu Wang, Ming Lv, Ying Jie Gao
{"title":"Study on eEF1A2’s mechanism in ameliorating the myocardial injury in ischemic cardiomyopathy via the AMPK/NF-κB signal pathway","authors":"Zhi Xing, Shajidan Abudureyimu, Palida Abulaiti, Yu Wang, Ming Lv, Ying Jie Gao","doi":"10.1007/s13273-025-00565-8","DOIUrl":"https://doi.org/10.1007/s13273-025-00565-8","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"22 1","pages":"165-177"},"PeriodicalIF":0.0,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147909954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The regulatory role and molecular mechanism of lncRNA ITGB2-AS1 in ferroptosis of non-small cell lung cancer cells lncRNA ITGB2-AS1在非小细胞肺癌细胞铁下垂中的调控作用及分子机制
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-08-27 DOI: 10.1007/s13273-025-00566-7
Qichang Jiang, Yan Lv, Yang Liu, Longfeng Gu, Hui Wang, Yanmiao Yang
{"title":"The regulatory role and molecular mechanism of lncRNA ITGB2-AS1 in ferroptosis of non-small cell lung cancer cells","authors":"Qichang Jiang, Yan Lv, Yang Liu, Longfeng Gu, Hui Wang, Yanmiao Yang","doi":"10.1007/s13273-025-00566-7","DOIUrl":"https://doi.org/10.1007/s13273-025-00566-7","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"22 1","pages":"179-189"},"PeriodicalIF":0.0,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147922599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacological inhibition of IRE1α-XBP1 pathway ameliorates age-associated sarcopenia by regulating ferroptosis in SAMP8 mice IRE1α-XBP1途径的药理抑制通过调节SAMP8小鼠的铁凋亡来改善年龄相关的肌肉减少症
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-07-18 DOI: 10.1007/s13273-025-00557-8
Ying Liu, Xin Li, Yuan Yuan, Xiaohui Deng, Bin Fan, Xiaoyan Liu, Wei Tian
{"title":"Pharmacological inhibition of IRE1α-XBP1 pathway ameliorates age-associated sarcopenia by regulating ferroptosis in SAMP8 mice","authors":"Ying Liu, Xin Li, Yuan Yuan, Xiaohui Deng, Bin Fan, Xiaoyan Liu, Wei Tian","doi":"10.1007/s13273-025-00557-8","DOIUrl":"https://doi.org/10.1007/s13273-025-00557-8","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"22 1","pages":"79-91"},"PeriodicalIF":0.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147906053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TCF21 mediates ITGA8 to block LUAD progression and immune escape TCF21介导ITGA8阻断LUAD进展和免疫逃逸
4区 医学
Molecular & Cellular Toxicology Pub Date : 2025-06-26 DOI: 10.1007/s13273-025-00551-0
Lei Zhu, Qian Yang, Shirui Ding, Tao Song, Yu-bing Zhou
{"title":"TCF21 mediates ITGA8 to block LUAD progression and immune escape","authors":"Lei Zhu, Qian Yang, Shirui Ding, Tao Song, Yu-bing Zhou","doi":"10.1007/s13273-025-00551-0","DOIUrl":"https://doi.org/10.1007/s13273-025-00551-0","url":null,"abstract":"","PeriodicalId":18683,"journal":{"name":"Molecular & Cellular Toxicology","volume":"22 1","pages":"31-45"},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147913677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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