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Cluster analysis of nursing effects on wound pain and healing of bedridden patients with pressure injuries. 对卧床压伤患者伤口疼痛和愈合的护理效果进行聚类分析。
IF 4.7 4区 医学
Minerva medica Pub Date : 2024-06-01 Epub Date: 2023-06-29 DOI: 10.23736/S0026-4806.23.08746-3
Qing Xu, Mimi Sheng, Yaxiao Sun
{"title":"Cluster analysis of nursing effects on wound pain and healing of bedridden patients with pressure injuries.","authors":"Qing Xu, Mimi Sheng, Yaxiao Sun","doi":"10.23736/S0026-4806.23.08746-3","DOIUrl":"10.23736/S0026-4806.23.08746-3","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9749727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SNHG7 regulates spinal cord injury-induced inflammatory response, oxidative stress, and apoptosis via the miR-199b-5p/TRAF3 axis. SNHG7通过miR-199b-5p/TRAF3轴调节脊髓损伤诱导的炎症反应、氧化应激和细胞凋亡
IF 4.7 4区 医学
Minerva medica Pub Date : 2024-06-01 Epub Date: 2023-06-13 DOI: 10.23736/S0026-4806.23.08689-5
Xiangli Luo, Zhan Wang, Jiancheng Xu, Zhao Gao, Zhengdong Song, Wenji Wang
{"title":"SNHG7 regulates spinal cord injury-induced inflammatory response, oxidative stress, and apoptosis via the miR-199b-5p/TRAF3 axis.","authors":"Xiangli Luo, Zhan Wang, Jiancheng Xu, Zhao Gao, Zhengdong Song, Wenji Wang","doi":"10.23736/S0026-4806.23.08689-5","DOIUrl":"10.23736/S0026-4806.23.08689-5","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9994585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LINC00858 facilitates the malignant development of Wilms' Tumor by targeting miR-653-5p. LINC00858 通过靶向 miR-653-5p 促进了 Wilms 肿瘤的恶性发展。
IF 4.7 4区 医学
Minerva medica Pub Date : 2024-06-01 Epub Date: 2020-06-12 DOI: 10.23736/S0026-4806.20.06566-0
Dan Zhou, Jilan Wang, Suping Xu, Zengming Li, Dan Kou
{"title":"LINC00858 facilitates the malignant development of Wilms' Tumor by targeting miR-653-5p.","authors":"Dan Zhou, Jilan Wang, Suping Xu, Zengming Li, Dan Kou","doi":"10.23736/S0026-4806.20.06566-0","DOIUrl":"10.23736/S0026-4806.20.06566-0","url":null,"abstract":"<p><strong>Background: </strong>To uncover the clinical significance of LINC00858 in the development of Wilms' Tumor and the potential molecular mechanism.</p><p><strong>Methods: </strong>LINC00858 levels in Wilms' Tumor species and cell lines were determined by quantitative real-time polymerase chain reaction (qRT-PCR). The clinical significance of LINC00858 in influencing pathological features and prognosis in patients with Wilms' Tumor was analyzed. Proliferative and migratory changes in Wilms' Tumor cells with LINC00858 knockdown were assessed. The downstream gene of LINC00858 was verified by luciferase assay, and its involvement in the development of Wilms' Tumor was further explored.</p><p><strong>Results: </strong>LINC00858 was highly expressed in Wilms' Tumor tissues and cell lines. High level of LINC00858 was correlated to high rate of lymphatic metastasis and poor prognosis in patients with Wilms' Tumor. Knockdown of LINC00858 suppressed proliferative and migratory potentials in HFWT and 17-94 cells. MiR-653-5p was targeted by LINC00858. It was lowly expressed in Wilms' Tumor tissues and negatively regulated by LINC00858. Knockdown of miR-653-5p partially abolished the regulatory effects of LINC00858 on proliferative and migratory potentials in Wilms' Tumor cells.</p><p><strong>Conclusions: </strong>LINC00858 is highly expressed in Wilms' Tumor species and correlated to lymphatic metastasis rate and overall survival in patients with Wilms' Tumor. Knockdown of LINC00858 suppresses Wilms' Tumor cells to proliferate and migrate via targeting miR-653-3p.</p>","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38049163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exosomal leptin accelerates gallbladder carcinoma by promoting M2-subtype macrophage polarization. 外泌体瘦素通过促进M2亚型巨噬细胞极化加速胆囊癌的发生
IF 4.7 4区 医学
Minerva medica Pub Date : 2024-04-01 Epub Date: 2023-05-04 DOI: 10.23736/S0026-4806.23.08612-3
Lixin Liu, Yunxia Liu, Ya Zhu, Qiang Kang, Songling Zhao, Wei Wang, Hao Zou
{"title":"Exosomal leptin accelerates gallbladder carcinoma by promoting M2-subtype macrophage polarization.","authors":"Lixin Liu, Yunxia Liu, Ya Zhu, Qiang Kang, Songling Zhao, Wei Wang, Hao Zou","doi":"10.23736/S0026-4806.23.08612-3","DOIUrl":"10.23736/S0026-4806.23.08612-3","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9461642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imaging characteristics of left ventricular diastolic function in patients with dilated cardiomyopathy using three-dimensional speckle tracking imaging and MRI. 利用三维斑点追踪成像和核磁共振成像观察扩张型心肌病患者左心室舒张功能的成像特征。
IF 4.7 4区 医学
Minerva medica Pub Date : 2024-04-01 Epub Date: 2023-05-11 DOI: 10.23736/S0026-4806.23.08625-1
Yingjie Xu, Jing Zhu
{"title":"Imaging characteristics of left ventricular diastolic function in patients with dilated cardiomyopathy using three-dimensional speckle tracking imaging and MRI.","authors":"Yingjie Xu, Jing Zhu","doi":"10.23736/S0026-4806.23.08625-1","DOIUrl":"10.23736/S0026-4806.23.08625-1","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9443093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical effect of Guizhi Fuling Pill combined with metformin on chronic pelvic inflammatory disease and its influence on inflammatory reaction in rats. 桂枝茯苓丸联合二甲双胍对慢性盆腔炎的临床疗效及其对大鼠炎症反应的影响
IF 4.7 4区 医学
Minerva medica Pub Date : 2024-04-01 Epub Date: 2023-05-04 DOI: 10.23736/S0026-4806.23.08616-0
Shuang Han, Yinhui Ji, Yaping Song, Shiqin Wang
{"title":"Clinical effect of Guizhi Fuling Pill combined with metformin on chronic pelvic inflammatory disease and its influence on inflammatory reaction in rats.","authors":"Shuang Han, Yinhui Ji, Yaping Song, Shiqin Wang","doi":"10.23736/S0026-4806.23.08616-0","DOIUrl":"10.23736/S0026-4806.23.08616-0","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9758027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The improvement effect of acupuncture combined with massage on shoulder pain after stroke and its impact on limb function. 针灸结合推拿对中风后肩痛的改善效果及其对肢体功能的影响
IF 4.7 4区 医学
Minerva medica Pub Date : 2024-04-01 DOI: 10.23736/S0026-4806.24.09269-3
Xiaonan Wang, Shaofeng Sun, Dongsheng Yu, Hua Yu
{"title":"The improvement effect of acupuncture combined with massage on shoulder pain after stroke and its impact on limb function.","authors":"Xiaonan Wang, Shaofeng Sun, Dongsheng Yu, Hua Yu","doi":"10.23736/S0026-4806.24.09269-3","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09269-3","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140776701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of gut microbiota in host immune response mechanisms. 肠道微生物群在宿主免疫反应机制中的作用。
IF 4.7 4区 医学
Minerva medica Pub Date : 2024-04-01 DOI: 10.23736/S0026-4806.24.09224-3
Jiaping Song, Yongcheng Xu, Tingting Wang, He Yu, He Dong
{"title":"The role of gut microbiota in host immune response mechanisms.","authors":"Jiaping Song, Yongcheng Xu, Tingting Wang, He Yu, He Dong","doi":"10.23736/S0026-4806.24.09224-3","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09224-3","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140796593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How primary care research can be improved in clinical practice? An Italian case study. 如何在临床实践中改进初级保健研究？意大利案例研究。
IF 4.7 4区 医学
Minerva medica Pub Date : 2024-04-01 DOI: 10.23736/S0026-4806.24.09044-X
A. Roveta, G. Pacileo, Mauro Cappelletti, Donatella Alesso, Alberto Bonissone, Lorenzo Fossati, Maria C Giaccari, Fabio Maccapani, Camillo Milano, Nicolò Parodi, Federico Torregiani, Francesca Ugo, Costanza Massarino, Luigi M Castello, A. Maconi
{"title":"How primary care research can be improved in clinical practice? An Italian case study.","authors":"A. Roveta, G. Pacileo, Mauro Cappelletti, Donatella Alesso, Alberto Bonissone, Lorenzo Fossati, Maria C Giaccari, Fabio Maccapani, Camillo Milano, Nicolò Parodi, Federico Torregiani, Francesca Ugo, Costanza Massarino, Luigi M Castello, A. Maconi","doi":"10.23736/S0026-4806.24.09044-X","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09044-X","url":null,"abstract":"BACKGROUND\u0000Primary care is considered essential for the sustainability of the Health System. Practice-Based Research Networks (PBRN) play a strategic role in translation of primary care research into practice. Research Capacity Building in primary care requires a improvement and development strategy and well-developed research infrastructures to support physicians.\u0000\u0000\u0000METHODS\u0000We used the system development methodology referring to the Lean Thinking to create and support a research team in primary and pediatric care. In particular a \"cascade\" deployment model and the X-Matrix, a framework used in management studies to support strategy definition and management process.\u0000\u0000\u0000RESULTS\u0000A research unit in primary and pediatric care has been created, by sharing vision, mission, core values, long-term strategies. The definition of a annual planning led to monitoring actions to guarantee the expected goals.\u0000\u0000\u0000CONCLUSIONS\u0000Lean methodology is useful to adapt to various managerial and operational contexts, including healthcare. In our case it allowed team members to spread the culture of research, its importance and role to improve the health of patients, thank to the organizational support of a hospital IR, the Research and Innovation Department.","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140775147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current status and influencing factors of death anxiety in family caregivers of advanced cancer patients. 晚期癌症患者家庭照顾者死亡焦虑的现状和影响因素。
IF 4.7 4区 医学
Minerva medica Pub Date : 2024-04-01 DOI: 10.23736/S0026-4806.24.09239-5
Xiaoli Bu, Binghan Tang, Jianai Zheng, Yi Wang
{"title":"Current status and influencing factors of death anxiety in family caregivers of advanced cancer patients.","authors":"Xiaoli Bu, Binghan Tang, Jianai Zheng, Yi Wang","doi":"10.23736/S0026-4806.24.09239-5","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09239-5","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140789166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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