Medical mycology最新文献_第7页

Evaluation of an in-house Pan-Malassezia quantitative PCR in human clinical samples 对人体临床样本中泛马拉色菌内部定量 PCR 的评估

IF 2.9 3区医学

Medical mycology Pub Date : 2024-09-14 DOI: 10.1093/mmy/myae095

Victor Euzen, Théo Ghelfenstein-Ferreira, Yasmine Benhadid-Brahmi, Alexandra Teboul, Sarah Dellière, Mazouz Benderdouche, Véronique Charlier, Marie Desnos-Ollivier, Samia Hamane, Alexandre Alanio

{"title":"Evaluation of an in-house Pan-Malassezia quantitative PCR in human clinical samples","authors":"Victor Euzen, Théo Ghelfenstein-Ferreira, Yasmine Benhadid-Brahmi, Alexandra Teboul, Sarah Dellière, Mazouz Benderdouche, Véronique Charlier, Marie Desnos-Ollivier, Samia Hamane, Alexandre Alanio","doi":"10.1093/mmy/myae095","DOIUrl":"https://doi.org/10.1093/mmy/myae095","url":null,"abstract":"Althought Malassezia spp. have been involved in various pathologies, they are integral part of the cutaneous, gut, oral, ears, nose and throat (ENT) mycobiota. Since Malassezia are difficult to grow in culture, unexhaustive molecular biology methods have been developed to detect them. The aim of the study was to evaluate an in-house pan-Malassezia quantitative PCR (panM-qPCR) on various clinical human samples and determine Malassezia burden in various human mycobiota. The panM-qPCR was designed to target the repeated 28S rDNA gene from all Malassezia species. We used the assay to quantify the Malassezia burden on 361 samples from 161 subjects (80 skin swabs from 10 healthy volunteers (HV), 13 samples from 2 seborrheic dermatitis patients (SD), 90 skin samples from 19 burned patients, 119 stools samples from 89 immunocompromised patients, 59 ENT samples from 41 patients). For HV, the amount of Malassezia was different according to the swabbed areas. Cq in SD are lower than in HV. In burned patients, Cq was significantly lower compared to HV. In stool samples, 6.7% were positive for Malassezia spp. with a high Cq. For the ENT area, a higher proportion of positive specimens were detected in ears samples than in nose samples. Our findings emphasized the importance of qPCR, confirming elevated Malassezia spp. levels on individuals' faces and scapls, increased burden in SD patients and in severely burnt patients than in HV. The pan-MqPCR appears to be a promising tool for studying Malassezia in various human mycobiota.","PeriodicalId":18586,"journal":{"name":"Medical mycology","volume":"40 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142265575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A review of lobomycosis and lobomycosis-like skin disease in cetaceans worldwide, with new data from the Gulf of Guayaquil, Ecuador. 回顾全球鲸目动物的龙霉菌病和龙霉菌病样皮肤病，以及厄瓜多尔瓜亚基尔湾的新数据。

IF 2.7 3区医学

Medical mycology Pub Date : 2024-09-06 DOI: 10.1093/mmy/myae089

Marie-Françoise Van Bressem, Fernando Félix, Koen Van Waerebeek

{"title":"A review of lobomycosis and lobomycosis-like skin disease in cetaceans worldwide, with new data from the Gulf of Guayaquil, Ecuador.","authors":"Marie-Françoise Van Bressem, Fernando Félix, Koen Van Waerebeek","doi":"10.1093/mmy/myae089","DOIUrl":"10.1093/mmy/myae089","url":null,"abstract":"Lobomycosis, also called paracoccidioidomycosis ceti, is a chronic mycotic cutaneous disease affecting odontocetes. Lobomycosis-like disease (LLD) has a clinical presentation consistent with lobomycosis but lacks a histological and molecular diagnosis. We review the literature on lobomycosis aetiology, clinical signs and pathogenesis, species affected and geographic distribution and examine the factors influencing the presence, transmission and prevalence of the disease, to better understand its ecology. In addition, we provide unpublished information on LLD in two common bottlenose dolphin (Tursiops truncatus) communities inhabiting the Gulf of Guayaquil, Ecuador. Lobomycosis and LLD occur in Delphinidae from the Atlantic, Pacific, and Indian Oceans between 33°N and 35°S. Primary risk factors include habitat, sex, age, sociality, and pollution. In dolphins from the Americas and Japan, lobomycosis is caused by Paracoccidioides ceti, family Ajellomycetaceae. The disease is characterized by cutaneous granulomatous lesions that may occur anywhere on the body, grow to large size, and may ulcerate. Histologically, the lesions consist of acanthosis and histiocytic granulomas between the skin and subcutaneous tissues, with inflammatory changes that extend deep into the dermis. Multiple yeast cells with a double refringent layer stained positive using Gomori-Grocott methenamine silver in the dermis of a T. truncatus from Ecuador diagnosed with LLD since 2011, a first record for the Southeast Pacific. Injuries may enable the entry of P. ceti into the dermis while skin contact likely favours transmission, putting males at higher risk than females. Lobomycosis and LLD may have a negative impact on small communities already threatened by anthropogenic factors.","PeriodicalId":18586,"journal":{"name":"Medical mycology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142109365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The significance of low titer serum cryptococcal antigen testing from 2017 to 2023 performed in a tertiary care center. 2017 年至 2023 年在三级医疗中心进行的低滴度血清隐球菌抗原检测的意义。

IF 2.7 3区医学

Medical mycology Pub Date : 2024-09-06 DOI: 10.1093/mmy/myae093

Thein Myint, Jenna R Wilson, Mahesh Bhatt, Mark E Irwin, Julie A Ribes

引用次数: 0

Candida auris: Understanding the dynamics of C. auris infection versus colonization. 念珠菌：了解念珠菌感染与定植的动态变化。

IF 2.7 3区医学

Medical mycology Pub Date : 2024-09-06 DOI: 10.1093/mmy/myae086

Sungsoo Park, Heesuk Kim, Duckjin Hong, Hyeyoung Oh

{"title":"Candida auris: Understanding the dynamics of C. auris infection versus colonization.","authors":"Sungsoo Park, Heesuk Kim, Duckjin Hong, Hyeyoung Oh","doi":"10.1093/mmy/myae086","DOIUrl":"10.1093/mmy/myae086","url":null,"abstract":"Candida auris is a pathogen of growing public health concern worldwide. However, risk factors contributing to C. auris infection in patients colonized with C. auris remain unclear. Understanding these risk factors is crucial to prevent colonization-to-infection transition and devise effective preventive strategies. This study aimed to investigate risk factors associated with C. auris infection compared to colonization. The study included 97 patients who acquired laboratory-confirmed C. auris in either matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry or VITEK 2 system from October 2019 to June 2023. Baseline demographics and known risk factors associated with C. auris infection were collected from electronic medical records. The infection group had C. auris from a sterile site or non-sterile site with evidence of infection. The colonization group was followed up for a median of 30 days for any signs of infection. Associations between relevant variables and C. auris infection were assessed using multivariable logistic regression. The infection group (n = 31) was more likely to be bedbound, with longer hospital stays and more arterial catheters. Chronic kidney disease (odds ratio [OR] 45.070), carriage of multidrug-resistant organisms (OR 64.612), and vasopressor use for > 20 days (OR 68.994) were associated with C. auris infection, after adjusting for sex, age, and prior colonization with C. auris. Chronic kidney disease, carriage of multidrug-resistant organisms, and prolonged vasopressor use emerged as significant risk factors for C. auris infection compared to colonization. They could be used to predict C. auris infection early in patients colonized with C. auris.","PeriodicalId":18586,"journal":{"name":"Medical mycology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141996143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular analysis of cutaneous yeast isolates in the mycobiota of children with atopic dermatitis. 特应性皮炎患儿真菌生物群中皮肤酵母分离物的分子分析。

IF 2.7 3区医学

Medical mycology Pub Date : 2024-09-06 DOI: 10.1093/mmy/myae090

Iwyna França Souza Gomes Vial, Morgana Ferreira Voidaleski, Rosângela Ferreira Lameira, Flavia de Fatima Costa, Danielle Arake Zanatta, Vania Aparecida Vicente, Vania Oliveira de Carvalho

{"title":"Molecular analysis of cutaneous yeast isolates in the mycobiota of children with atopic dermatitis.","authors":"Iwyna França Souza Gomes Vial, Morgana Ferreira Voidaleski, Rosângela Ferreira Lameira, Flavia de Fatima Costa, Danielle Arake Zanatta, Vania Aparecida Vicente, Vania Oliveira de Carvalho","doi":"10.1093/mmy/myae090","DOIUrl":"10.1093/mmy/myae090","url":null,"abstract":"The skin of patients with atopic dermatitis (AD) has a greater diversity of mycobiota. An observational, prospective, cross-sectional, analytical, and comparative study was conducted involving 80 patients with AD Group (ADG) and 50 individuals without AD (wADG) in a tertiary hospital in Brazil. Skin scale samples were collected from the frontal, cervical, fossae cubital, and popliteal regions and identified using molecular biology techniques. The results showed that 47.5% of ADG had identified yeasts compared to 0% of wADG (P < .001). The yeasts Rhodotorula mucilaginosa and Candida parapsilosis were the most abundant. The probability of colonization increased with age, showing values of 40% at 60 months and 80% at 220 months (P = .09). The cervical region (12.5%) was colonized to the greatest extent. Our findings revealed that positive mycology was not more probable when the scoring of atopic dermatitis or eczema area and severity index value increased (P = .23 and .53, respectively). The results showed that the sex, age, and different population types directly affected the composition of the mycobiota in the population analyzed. A higher frequency of colonization and greater diversity of yeast species were detected in the cutaneous mycobiota of children with AD.","PeriodicalId":18586,"journal":{"name":"Medical mycology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142109366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A global perspective of the changing epidemiology of invasive fungal disease and real-world experience with the use of isavuconazole. 从全球角度看侵袭性真菌病流行病学的变化以及使用异黄酮唑的实际经验。

IF 2.7 3区医学

Medical mycology Pub Date : 2024-09-06 DOI: 10.1093/mmy/myae083

George R Thompson, Sharon C-A Chen, Wadha Ahmed Alfouzan, Koichi Izumikawa, Arnaldo L Colombo, Johan Maertens

{"title":"A global perspective of the changing epidemiology of invasive fungal disease and real-world experience with the use of isavuconazole.","authors":"George R Thompson, Sharon C-A Chen, Wadha Ahmed Alfouzan, Koichi Izumikawa, Arnaldo L Colombo, Johan Maertens","doi":"10.1093/mmy/myae083","DOIUrl":"10.1093/mmy/myae083","url":null,"abstract":"Global epidemiological data show that the incidence of invasive fungal disease (IFD) has increased in recent decades, with the rising frequency of infections caused by Aspergillus and Mucorales order species. The number and variety of patients at risk of IFD has also expanded, owing in part to advances in the treatment of hematologic malignancies and other serious diseases, including hematopoietic stem cell transplantation (HCT) and other therapies causing immune suppression. Isavuconazonium sulfate (active moiety: isavuconazole) is an advanced-generation triazole antifungal approved for the treatment of invasive aspergillosis and mucormycosis that has demonstrated activity against a variety of yeasts, moulds, and dimorphic fungi. While real-world clinical experience with isavuconazole is sparse in some geographic regions, it has been shown to be effective and well tolerated in diverse patient populations, including those with multiple comorbidities who may have failed to respond to prior triazole antifungal therapy. Isavuconazole may be suitable for patients with IFD receiving concurrent QTc-prolonging therapy, as well as those on venetoclax or ruxolitinib. Data from clinical trials are not available to support the use of isavuconazole prophylactically for the prevention of IFD or for the treatment of endemic IFD, such as those caused by Histoplasma spp., but real-world evidence from case studies suggests that it has clinical utility in these settings. Isavuconazole is an option for patients at risk of IFD, particularly when the use of alternative antifungal therapies is not possible because of toxicities, pharmacokinetics, or drug interactions.","PeriodicalId":18586,"journal":{"name":"Medical mycology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11382804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Landscape of in situ cytokine expression, soluble C-type lectin receptors, and vitamin D in patients with recurrent vulvovaginal candidiasis. 复发性外阴阴道念珠菌病患者原位细胞因子表达、可溶性 C 型凝集素受体和维生素 D 的分布。

IF 2.7 3区医学

Medical mycology Pub Date : 2024-09-06 DOI: 10.1093/mmy/myae091

Jeiser Marcelo Consuegra-Asprilla, Manuela Chaverra-Osorio, Brajhan Torres, Yuliana Cabrera-Chingal, Angelica Mancera-Mieles, Carolina Rodríguez-Echeverri, Beatriz L Gómez, Ángel González

{"title":"Landscape of in situ cytokine expression, soluble C-type lectin receptors, and vitamin D in patients with recurrent vulvovaginal candidiasis.","authors":"Jeiser Marcelo Consuegra-Asprilla, Manuela Chaverra-Osorio, Brajhan Torres, Yuliana Cabrera-Chingal, Angelica Mancera-Mieles, Carolina Rodríguez-Echeverri, Beatriz L Gómez, Ángel González","doi":"10.1093/mmy/myae091","DOIUrl":"10.1093/mmy/myae091","url":null,"abstract":"The immunopathogenesis of recurrent vulvovaginal candidiasis (RVVC) is poorly understood. Recently, it was reported that patients with RVVC present a decrease in both the fungicidal capacity of neutrophils and the proliferative capability of peripheral blood mononuclear cells in response to Candida albicans infection, suggesting an alteration in the innate and adaptive immune response. The aim of this study was to determine the in-situ expression, in the vaginal mucosa, of genes associated with the immune response, as well as the serum concentrations of dectin-1, mannose-binding lectin (MBL), and vitamin D in patients with RVVC. A study was carried out on 40 patients with a diagnosis of RVVC and 26 healthy women. Vaginal scrapings were obtained, and the expression of genes that encode cytokines and transcription factors specific for Th1, Th2, Th17, Treg, pro-inflammatory profiles, and enzymes related to oxidative/microbicidal mechanisms was evaluated by quantitiative polymerase chain reaction (qPCR). Additionally, serum levels of vitamin D and the soluble receptors dectin-1 and MBL were determined by enzyme-linked immunosorbent assay (ELISA). In patients with RVVC, a decreased expression of T-bet, RORγ-T, IL-1β, and IL-17, and an increase in the expression of FOXP3, IL-4, IL-8, IL-10, and IL-18 were observed when compared to healthy women: moreover, decreased levels of MBL were also observed in these patients. These results confirm that patients with RVVC present in-situ alterations in both the specific and adaptive immune response against Candida spp., a fact that could be associated with the exaggerated vaginal inflammatory response.","PeriodicalId":18586,"journal":{"name":"Medical mycology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular epidemiology and antifungal susceptibility of dermatophytes and Candida isolates in superficial fungal infections at a grade A tertiary hospital in Northern China. 华北某甲级三甲医院浅部真菌感染中皮真菌和念珠菌分离物的分子流行病学和抗真菌敏感性

IF 2.7 3区医学

Medical mycology Pub Date : 2024-09-06 DOI: 10.1093/mmy/myae087

Ruijun Zhang, Ziping Song, Xiaorui Su, Ting Li, Juan Xu, Xiao He, Yuanwen Yang, Bingmei Chang, Yuying Kang

{"title":"Molecular epidemiology and antifungal susceptibility of dermatophytes and Candida isolates in superficial fungal infections at a grade A tertiary hospital in Northern China.","authors":"Ruijun Zhang, Ziping Song, Xiaorui Su, Ting Li, Juan Xu, Xiao He, Yuanwen Yang, Bingmei Chang, Yuying Kang","doi":"10.1093/mmy/myae087","DOIUrl":"10.1093/mmy/myae087","url":null,"abstract":"This study analyzed the prevalence and antifungal susceptibility of superficial fungal infections in 295 cases from 2019 to 2020 at a dermatology clinic. Dermatophytes were the predominant pathogens (69.5%), including Trichophytonrubrum, T. interdigitale, Microsporum canis, et al., followed by Candida spp. (29.5%), including Candidaalbicans, Ca. parapsilosis, and Ca. glabrata. The most common infections were onychomycosis (36.3%), tinea cruris (30.5%), and tinea corporis (18.6%). The distribution of SFI types showed variations based on gender, age, and season. Common antifungal agents, including terbinafine, voriconazole, ciclopiroxamine, amphotericin B, itraconazole, and ketoconazole have exhibited low minimum inhibitory concentrations against dermatophytes, especially terbinafine, which has been potent against superficial fungal infections caused by dermatophytes in the local area. Candida spp. strains were generally susceptible or classified as wild-type to 5-flucytosine and amphotericin B, with 92.0% being wild-type for itraconazole. However, resistance to fluconazole and voriconazole was observed in a small percentage of Ca. albicans and Ca. parapsilosis strains. The emergence of drug-resistant Candida underscores the importance of prudent antifungal use and continuous surveillance.","PeriodicalId":18586,"journal":{"name":"Medical mycology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142036340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deciphering prognostic indicators in non-HIV cryptococcal meningitis: Constructing and validating a predictive Nomogram model. 解密非艾滋病毒隐球菌脑膜炎的预后指标：构建并验证预测性提名图模型

IF 2.7 3区医学

Medical mycology Pub Date : 2024-09-06 DOI: 10.1093/mmy/myae092

Feng Liang, Runyang Li, Make Yao, Jing Wang, Yunhong Li, Lijian Lei, Junhong Guo, Xueli Chang

{"title":"Deciphering prognostic indicators in non-HIV cryptococcal meningitis: Constructing and validating a predictive Nomogram model.","authors":"Feng Liang, Runyang Li, Make Yao, Jing Wang, Yunhong Li, Lijian Lei, Junhong Guo, Xueli Chang","doi":"10.1093/mmy/myae092","DOIUrl":"10.1093/mmy/myae092","url":null,"abstract":"Cryptococcal meningitis (CM) is a well-recognized fungal infection, with substantial mortality in individuals infected with the human immunodeficiency virus (HIV). However, the incidence, risk factors, and outcomes in non-HIV adults remain poorly understood. This study aims to investigate the characteristics and prognostic indicators of CM in non-HIV adult patients, integrating a novel predictive model to guide clinical decision-making. A retrospective cohort of 64 non-HIV adult CM patients, including 51 patients from previous studies and 13 from the First Hospital of Shanxi Medical University, was analyzed. We assessed demographic features, underlying diseases, intracranial pressure, cerebrospinal fluid characteristics, and brain imaging. Using the least absolute shrinkage and selection operator (LASSO) method, and multivariate logistic regression, we identified significant variables and constructed a Nomogram prediction model. The model's calibration, discrimination, and clinical value were evaluated using the Bootstrap method, calibration curve, C index, goodness-of-fit test, receiver operating characteristic (ROC) analysis, and decision curve analysis. Age, brain imaging showing parenchymal involvement, meningeal and ventricular involvement, and previous use of immunosuppressive agents were identified as significant variables. The Nomogram prediction model displayed satisfactory performance with an akaike information criterion (AIC) value of 72.326, C index of 0.723 (0.592-0.854), and area under the curve (AUC) of 0.723, goodness-of-fit test P = 0.995. This study summarizes the clinical and imaging features of adult non-HIV CM and introduces a tailored Nomogram prediction model to aid in patient management. The identification of predictive factors and the development of the nomogram enhance our understanding and capacity to treat this patient population. The insights derived have potential clinical implications, contributing to personalized care and improved patient outcomes.","PeriodicalId":18586,"journal":{"name":"Medical mycology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to: Comparison of Candida colonization in intensive care unit patients with and without COVID-19: First prospective cohort study from Turkey. 更正：有 COVID-19 和没有 COVID-19 的重症监护室患者念珠菌定植情况比较：土耳其首次前瞻性队列研究。

IF 2.7 3区医学

Medical mycology Pub Date : 2024-08-02 DOI: 10.1093/mmy/myae078

引用次数: 0