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Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics最新文献

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Challenges and possibilities for developing adaptive optics: ultra-high resolution optical coherence tomography for clinical in vivo retinal imaging 发展自适应光学的挑战和可能性:用于临床体内视网膜成像的超高分辨率光学相干断层扫描
Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics Pub Date : 2008-09-26 DOI: 10.1117/12.819169
R. Zawadzki, Stacey S. Choi, J. W. Evans, J. Werner
{"title":"Challenges and possibilities for developing adaptive optics: ultra-high resolution optical coherence tomography for clinical in vivo retinal imaging","authors":"R. Zawadzki, Stacey S. Choi, J. W. Evans, J. Werner","doi":"10.1117/12.819169","DOIUrl":"https://doi.org/10.1117/12.819169","url":null,"abstract":"Recent developments in adaptive optics - optical coherence tomography (AO-OCT) allow for ultra-high isotropic resolution imaging of the in-vivo retina, offering unprecedented insight into its volumetric microscopic and cellular structures. In addition to this promising achievement, the clinical impact and application of this technology still needs to be explored. This includes assessment of limitations and challenges for existing as well as future AO-OCT systems, especially in the context of potential transfer of this technology from an optical bench to a portable imaging system. To address these issues we will describe our current AO-UHR-OCT focusing on its sub-components, as well as application for clinical imaging. Additionally, we describe some directions for future development of our AO-OCT instrument that would improve its clinical utility including: new compact AO-OCT design, new improved AO sub-system (extreme AO), and new generations of Fourier-domain-OCT.","PeriodicalId":184459,"journal":{"name":"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114460262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple delay lines full-field optical coherence tomography 多延迟线全场光学相干层析成像
Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics Pub Date : 2008-09-26 DOI: 10.1117/12.822154
Jingyu Wang, C. Dainty, A. Podoleanu
{"title":"Multiple delay lines full-field optical coherence tomography","authors":"Jingyu Wang, C. Dainty, A. Podoleanu","doi":"10.1117/12.822154","DOIUrl":"https://doi.org/10.1117/12.822154","url":null,"abstract":"Full-field Optical Coherence Tomography (FF-OCT) is a parallel detection OCT technique using a 2D detector array. This technique avoids mechanical scanning in imaging optics. Therefore, it can speed up the imaging process and enhance the imaging quality. We present a FF-OCT instrument to be used in conjunction with the principle of multiple delays (MD) OCT to evaluate the topography of curved objects in a single-shot imaging. We evaluate the optimum combination of the MD principle with the FF-OCT method and measure the radius of a metal ball with this method. We managed to obtain 2n-1 contour lines using an MDE with n delays in a single en-face OCT image to evaluate the curvature of the object surface.","PeriodicalId":184459,"journal":{"name":"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125116175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Doppler optical coherence tomography in cardiovascular physiology 多普勒光学相干断层扫描在心血管生理学中的应用
Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics Pub Date : 2008-09-26 DOI: 10.1117/12.822553
M. Bonesi, I. Meglinski, S. Matcher
{"title":"Doppler optical coherence tomography in cardiovascular physiology","authors":"M. Bonesi, I. Meglinski, S. Matcher","doi":"10.1117/12.822553","DOIUrl":"https://doi.org/10.1117/12.822553","url":null,"abstract":"The study of flow dynamics in complex geometry vessels is highly important in many biomedical applications where the knowledge of the mechanic interactions between the moving fluid and the housing media plays a key role for the determination of the parameters of interest, including the effect of blood flow on the possible rupture of atherosclerotic plaques. Doppler Optical Coherence Tomography (DOCT), as a functional extension of Optical Coherence Tomography (OCT), is an optic, non-contact, non-invasive technique able to achieve detailed analysis of the flow/vessel interactions. It allows simultaneous high resolution imaging (10 μm typical) of the morphology and composition of the vessel and determination of the flow velocity distribution along the measured cross-section. We applied DOCT system to image high-resolution one-dimensional and multi-dimensional velocity distribution profiles of Newtonian and non-Newtonian fluids flowing in vessels with complex geometry, including Y-shaped and T-shaped vessels, vessels with aneurism, bifurcated vessels with deployed stent and scaffolds. The phantoms were built to mimic typical shapes of human blood vessels, enabling preliminary analysis of the interaction between flow dynamics and the (complex) geometry of the vessels and also to map the related velocity profiles at several inlet volume flow rates. Feasibility studies for quantitative observation of the turbulence of flows arising within the complex geometry vessels are discussed. In addition, DOCT technique was also applied for monitoring cerebral mouse blood flow in vivo. Two-dimensional DOCT images of complex flow velocity profiles in blood vessel phantoms and in vivo sub-cranial mouse blood flow velocities distributions are presented.","PeriodicalId":184459,"journal":{"name":"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121534249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-speed high-resolution optical coherence tomography at 800 and 1060 nm 800和1060纳米的高速高分辨率光学相干层析成像
Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics Pub Date : 2008-09-26 DOI: 10.1117/12.817399
B. Povazay, B. Hofer, B. Hermann, C. Torti, Vedran Kajic, A. Unterhuber, W. Drexler
{"title":"High-speed high-resolution optical coherence tomography at 800 and 1060 nm","authors":"B. Povazay, B. Hofer, B. Hermann, C. Torti, Vedran Kajic, A. Unterhuber, W. Drexler","doi":"10.1117/12.817399","DOIUrl":"https://doi.org/10.1117/12.817399","url":null,"abstract":"Two high speed systems for spectrometer based frequency domain optical coherence tomography are presented. A device operating at 800 nm, based on the Basler Sprint CMOS camera with linerates of up to 312,000 lps and a device based on the Goodrich SUI LHD 1024 px camera at 1060 nm with 47,000 lps are applied in a clinical environment to normal subjects. The feasibility of clinical high and ultra high-resolution optical coherence tomography (OCT) devices for retinal imaging at different wavelengths, capable of isotropic sampling with 70 to 600 frames per second at 512 depth scans/frame for widefield imaging and high density sampling at 1 Gvoxel are demostrated.","PeriodicalId":184459,"journal":{"name":"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129878880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Theory and applications of multi-beam OCT 多束OCT的理论与应用
Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics Pub Date : 2008-09-26 DOI: 10.1117/12.821006
J. Holmes
{"title":"Theory and applications of multi-beam OCT","authors":"J. Holmes","doi":"10.1117/12.821006","DOIUrl":"https://doi.org/10.1117/12.821006","url":null,"abstract":"The lateral resolution of Fourier domain optical coherence tomography (FD-OCT) systems is limited by the depth of focus that can be achieved over the desired imaging depth at the chosen wavelength. I present a solution in which multiple beams focused at different depths are scanned together, so that a mosaic image can be produced, with at least double the resolution possible from a single beam system. Side-benefits also arise from the ability to combine data from each beam to improve signal-to-noise. The theory of this approach is discussed, advantages, and also the practical realisation in a variety of ex-vivo and in-vivo OCT imaging probes, together with results from a number of applications.","PeriodicalId":184459,"journal":{"name":"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics","volume":"7139 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130716695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
Nanoparticles for enhanced contrast optical coherence tomography 用于增强对比度光学相干断层扫描的纳米颗粒
Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics Pub Date : 2008-09-26 DOI: 10.1117/12.818690
C. Maule, P. Quaresma, P. Carvalho, P. Jorge, E. Pereira, C. Rosa
{"title":"Nanoparticles for enhanced contrast optical coherence tomography","authors":"C. Maule, P. Quaresma, P. Carvalho, P. Jorge, E. Pereira, C. Rosa","doi":"10.1117/12.818690","DOIUrl":"https://doi.org/10.1117/12.818690","url":null,"abstract":"Recently the area of bioimaging has benefited from new types of image enhancing agents such as quantum dots, carbon nanotubes and other nanoparticles. Cellular or even molecular level resolution has been achieved with different techniques during these last years (i.a. Fluorescence microscopy, PET/CT scan, AFM). Optical Coherence Tomography (OCT) as an imaging technique should also profit from newly developed probes. In this work we explored the tunable properties of different types of nanoparticles as contrast enhancers in OCT applications. We mainly studied the development and characteristics of metallic nanoparticles with tunable properties: gold nanoshells made of a silica core coated with a gold shell. Nanoshell and nanoparticles processing techniques are discussed, as well as their optimization for designing particles with specific absorption and scattering characteristics, and its use in OCT imaging.","PeriodicalId":184459,"journal":{"name":"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130575172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
En-face OCT microleakage investigation after laser-assisted dental hard tissue treatment 激光辅助牙硬组织治疗后的正面OCT微渗漏研究
Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics Pub Date : 2008-09-26 DOI: 10.1117/12.814917
C. Todea, Cosmin Bălăbuc, C. Sinescu, M. Negruțiu, Laura Filip, A. Bradu, A. Podoleanu
{"title":"En-face OCT microleakage investigation after laser-assisted dental hard tissue treatment","authors":"C. Todea, Cosmin Bălăbuc, C. Sinescu, M. Negruțiu, Laura Filip, A. Bradu, A. Podoleanu","doi":"10.1117/12.814917","DOIUrl":"https://doi.org/10.1117/12.814917","url":null,"abstract":"Purpose: To investigate using en-face Optical Coherence Tomography (OCT) the microleakage after Er:YAG laser cavity preparation. Material and Methods: Thirty single- and multi-rooted freshly extracted human teeth divided into two study groups, group I (laser) and group II (control), were used in this study. In group I, Class V cavities were prepared using laser on the buccal surface of each tooth. The laser device used was an Er:YAG laser (2940 nm, VSP, 250-320 mJ, 10-20 Hz). In group II, cavities were prepared conventionally and acid etched on the oral surface of the same tooth. All cavities were filled with composite resin. The cavity microleakage was investigated using en-face Optical Coherence Tomography prototype, based on transverse scanning and operating at 1300 nm. Results: The investigation demonstrated qualitatively the reduction of microleakage in cavities prepared with Er:YAG laser as compared to the control group, in which cavities were prepared conventionally. Conclusion: The en-face OCT method provided a superior non-invasive and real time investigation method, thus reducing the occurrence of secondary caries by early detection. Moreover, based on the results of this investigation, it may be concluded that Er:YAG laser-assisted cavity preparation leads to reduction of microleakage.","PeriodicalId":184459,"journal":{"name":"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117058654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optical Coherence Tomography for non-destructive investigations of structure of easel paintings 用于对架上绘画结构进行非破坏性研究的光学相干断层扫描技术
Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics Pub Date : 2008-09-26 DOI: 10.1117/12.813477
E. Kwiatkowska, M. Sylwestrzak, Bogumiła J. Rouba, L. Tymińska-Widmer, M. Iwanicka, P. Targowski
{"title":"Optical Coherence Tomography for non-destructive investigations of structure of easel paintings","authors":"E. Kwiatkowska, M. Sylwestrzak, Bogumiła J. Rouba, L. Tymińska-Widmer, M. Iwanicka, P. Targowski","doi":"10.1117/12.813477","DOIUrl":"https://doi.org/10.1117/12.813477","url":null,"abstract":"In this contribution the application of Optical Coherence Tomography (OCT) for non-invasive structural imaging of easel paintings will be presented. Since the technique permits imaging semi-transparent layers accessible for infrared light, the varnish and glaze layers are usually under investigation. The major emphasis will be laid on application of OCT to resolving specific conservation problems, arising during the restoration process. The examples of imaging multilayer varnishes and subsequent alterations will be given and the application of these images for authentication of inscriptions will be discussed. Since the thickness of imaged layers may be directly measured with OCT in completely non-destructive, quick and convenient way as many times as necessary, the application of the technique to generation of varnish thickness maps will be presented.","PeriodicalId":184459,"journal":{"name":"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129224087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Optical coherence tomography for the investigation of posterior and anterior eye segments 光学相干断层扫描研究后、前眼段
Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics Pub Date : 2008-09-26 DOI: 10.1117/12.815185
Y. Yasuno
{"title":"Optical coherence tomography for the investigation of posterior and anterior eye segments","authors":"Y. Yasuno","doi":"10.1117/12.815185","DOIUrl":"https://doi.org/10.1117/12.815185","url":null,"abstract":"The applications of three-dimensional Fourier domain optical coherence tomography (FD-OCT) to ophthalmology are demonstrated. The fundamentals of two types of FD-OCT, i.e., spectral domain OCT (SD-OCT) and swept source OCT (SS-OCT) are described. The 3D investigation of age-related macular degeneration and keratoconus are presented.","PeriodicalId":184459,"journal":{"name":"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131930707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An innovative approach for investigating the ceramic bracket-enamel interface - optical coherence tomography and confocal microscopy 一种研究陶瓷支架-牙釉质界面的创新方法-光学相干层析成像和共聚焦显微镜
Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics Pub Date : 2008-09-26 DOI: 10.1117/12.814894
R. Romînu, C. Sinescu, M. Rominu, M. Negruțiu, Philippe Laissue, S. Mihali, L. Cuc, M. Hughes, A. Bradu, A. Podoleanu
{"title":"An innovative approach for investigating the ceramic bracket-enamel interface - optical coherence tomography and confocal microscopy","authors":"R. Romînu, C. Sinescu, M. Rominu, M. Negruțiu, Philippe Laissue, S. Mihali, L. Cuc, M. Hughes, A. Bradu, A. Podoleanu","doi":"10.1117/12.814894","DOIUrl":"https://doi.org/10.1117/12.814894","url":null,"abstract":"Bonding has become a routine procedure in several dental specialties - from prosthodontics to conservative dentistry and even orthodontics. In many of these fields it is important to be able to investigate the bonded interfaces to assess their quality. All currently employed investigative methods are invasive, meaning that samples are destroyed in the testing procedure and cannot be used again. We have investigated the interface between human enamel and bonded ceramic brackets non-invasively, introducing a combination of new investigative methods - optical coherence tomography (OCT) and confocal microscopy (CM). Brackets were conventionally bonded on conditioned buccal surfaces of teeth The bonding was assessed using these methods. Three dimensional reconstructions of the detected material defects were developed using manual and semi-automatic segmentation. The results clearly prove that OCT and CM are useful in orthodontic bonding investigations.","PeriodicalId":184459,"journal":{"name":"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127240673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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