Menopause: The Journal of The North American Menopause Society最新文献_第9页

Achieving Menopausal Health Equity Network (AMEN): an educational intervention to improve OB/GYN knowledge of menopause-related racial and ethnic health disparities. 实现绝经期健康公平网络（AMEN）：一项教育干预，以提高OB/GYN对绝经相关种族和民族健康差异的认识。

IF 2.8 3区医学

Menopause: The Journal of The North American Menopause Society Pub Date : 2025-07-01 DOI: 10.1097/GME.0000000000002545

Shilpa Kalluru, Celine M Akande, Margot B Bellon, Nikhita Mahendru, Dona Jalili, Amani Sampson, Steven R Goldstein, Margaret J Nachtigall, Lila E Nachtigall, Samantha M Dunham, Kameelah A Phillips, Gwendolyn P Quinn

{"title":"Achieving Menopausal Health Equity Network (AMEN): an educational intervention to improve OB/GYN knowledge of menopause-related racial and ethnic health disparities.","authors":"Shilpa Kalluru, Celine M Akande, Margot B Bellon, Nikhita Mahendru, Dona Jalili, Amani Sampson, Steven R Goldstein, Margaret J Nachtigall, Lila E Nachtigall, Samantha M Dunham, Kameelah A Phillips, Gwendolyn P Quinn","doi":"10.1097/GME.0000000000002545","DOIUrl":"10.1097/GME.0000000000002545","url":null,"abstract":"Objectives: To study the impact of an educational intervention on obstetrician-gynecologist clinicians' knowledge of racial and ethnic disparities in the menopause experience.Methods: Twenty-five obstetrician-gynecologist physicians (residents, fellows, and attendings) at an academic medical center in New York, NY, completed the Achieving Menopausal Health Equity Network course, a brief web-based intervention consisting of four modules delivered through narrated didactic videos and interactive tools, a 10-item pretest and posttest, and a course evaluation survey. The primary outcome was a change in knowledge scores after the completion of the educational intervention. Item analysis was also performed to assess item discrimination, item difficulty, and response frequency. Feedback on modules was obtained, and thematic analysis was performed.Results: In this study, 25 participants completed the educational intervention. There was a statistically significant increase in mean test scores after participation (pretest mean score=7.1/10 vs. posttest mean score=8.1/10, P =0.0021). The following themes emerged in thematic analysis: knowledge building with potential for practical application for clinicians and non-clinicians, clarity and relevance, and opportunities for growth for future iterations of the modules.Conclusions: This brief, online educational curriculum focused on racial and ethnic disparities in menopause significantly improved the knowledge of obstetrician-gynecologist clinicians at various levels of training and provides a useful model for introducing more formal training on menopause medicine for obstetrician-gynecologist clinicians.","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":"601-609"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cross-sectional study of the association between regular sexual activity and sexual function and genitourinary syndrome of menopause-related symptoms. 有规律的性活动与性功能和泌尿生殖系统综合征绝经相关症状之间关系的横断面研究。

IF 2.8 3区医学

Menopause: The Journal of The North American Menopause Society Pub Date : 2025-07-01 DOI: 10.1097/GME.0000000000002539

Yoshikazu Sato, Yumi Ozaki, Hikaru Tomoe, Noriko Ninomiya, Yuki Sekiguchi, Mayuko Yamamoto, Satoru Takahashi

{"title":"Cross-sectional study of the association between regular sexual activity and sexual function and genitourinary syndrome of menopause-related symptoms.","authors":"Yoshikazu Sato, Yumi Ozaki, Hikaru Tomoe, Noriko Ninomiya, Yuki Sekiguchi, Mayuko Yamamoto, Satoru Takahashi","doi":"10.1097/GME.0000000000002539","DOIUrl":"10.1097/GME.0000000000002539","url":null,"abstract":"Objectives: We assessed sexual symptoms and function in perimenopausal and postmenopausal Japanese women and examined the association between sexual regularity and their symptoms.Methods: Sexually active women aged 40-79 (n = 911) were selected from the genitourinary syndrome of menopause (GSM) in Japanese Women study (n = 4,134) and then divided into 2 groups: regular sexual activity group, which comprised women with sexual activity in the past 3 months (n = 716), and lower sexual activity group, which comprised women with sexual activity in the past year but not in the past 3 months (n = 195). We evaluated sexual function and symptoms in the regular sexual activity group using the Female Sexual Function Index and compared GSM-related symptoms between the two groups.Results: Sexual desire, arousal, and lubrication ability declined significantly with age. Sexual pain increases with age. However, orgasm and satisfaction did not decline significantly with age. Regular and lower sexual activity groups did not differ significantly in sexual symptoms; however, vulvar symptoms in daily life were significantly lower in the regular sexual activity group than in the lower activity group. Sexual activity in the past 3 months was associated with lower odds of vulvar pain, dryness, and irritation.Conclusions: This study reveals an association between regular sexual activity and low prevalence of GSM-related symptoms in daily life. The direction of this relationship could not be evaluated in this study and needs to be explored using prospective studies.","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":"592-600"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144497476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heartbeats and heatwaves: understanding palpitations in midlife women. 心跳和热浪：了解中年女性的心悸。

IF 2.8 3区医学

Menopause: The Journal of The North American Menopause Society Pub Date : 2025-07-01 DOI: 10.1097/GME.0000000000002604

Nancy Safwan, Amy W Pollak, Chrisandra L Shufelt

引用次数: 0

The rediscovery of estetrol and its implications for estrogen treatment. 重新发现甾醇及其对雌激素治疗的意义。

IF 2.8 3区医学

Menopause: The Journal of The North American Menopause Society Pub Date : 2025-07-01 DOI: 10.1097/GME.0000000000002537

Herjan J T Coelingh Bennink, Roger Gosden, Frank Z Stanczyk, Eli Y Adashi

{"title":"The rediscovery of estetrol and its implications for estrogen treatment.","authors":"Herjan J T Coelingh Bennink, Roger Gosden, Frank Z Stanczyk, Eli Y Adashi","doi":"10.1097/GME.0000000000002537","DOIUrl":"10.1097/GME.0000000000002537","url":null,"abstract":"Objectives: To summarize the literature on the rediscovery and clinical exploration of the fourth natural estrogen estetrol (E4), more than 100 years after the discovery of estrone (E1), estradiol (E2), and estriol (E3).Methods: Literature review of E4 publications.Results: Preclinical and clinical research and development of E4 revealed that: (1) contrary to the other 3 natural estrogens, E4 has a high oral bioavailability, and (2) oral E4 has limited effect on hemostasis and other liver functions, and is, therefore, expected to be a safer estrogen. Since 2022, E4 combined with drospirenone has been registered worldwide as an oral contraceptive. E4 for menopausal hormone therapy is expected to become available in 2026. Clinical development of the use of E4 for the treatment of advanced breast cancer and advanced prostate cancer is ongoing, and E4 has been proposed as a component of an oral male contraceptive.Conclusion: The recognition of E4 as a useful and safe natural estrogen for human use is expected to change the scene of estrogen treatment in women and men significantly.","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":"32 7","pages":"648-651"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genitourinary syndrome of menopause-it has only just begun! 更年期泌尿生殖系统综合症——它才刚刚开始！

IF 2.8 3区医学

Menopause: The Journal of The North American Menopause Society Pub Date : 2025-07-01 DOI: 10.1097/GME.0000000000002601

Marcie K Richardson

引用次数: 0

Bladder health in the menopausal transition: a critical yet underrecognized dimension of midlife health. 膀胱健康在更年期过渡：一个关键但未被认识到的中年健康的维度。

IF 2.8 3区医学

Menopause: The Journal of The North American Menopause Society Pub Date : 2025-07-01 DOI: 10.1097/GME.0000000000002591

Bence Kozma, Peter Takacs

引用次数: 0

Spontaneous pyometra in postmenopausal women and gynecologic cancer-a preliminary study based on experience of a tertiary medical center. 绝经后妇女自发性子宫积脓与妇科癌症——基于三级医疗中心经验的初步研究。

IF 2.8 3区医学

Menopause: The Journal of The North American Menopause Society Pub Date : 2025-07-01 DOI: 10.1097/GME.0000000000002600

Yael Tal Bliman, Tal Rafaeli Yehudai, Yair Shiber, Matan Mor, Zvi Vaknin

{"title":"Spontaneous pyometra in postmenopausal women and gynecologic cancer-a preliminary study based on experience of a tertiary medical center.","authors":"Yael Tal Bliman, Tal Rafaeli Yehudai, Yair Shiber, Matan Mor, Zvi Vaknin","doi":"10.1097/GME.0000000000002600","DOIUrl":"https://doi.org/10.1097/GME.0000000000002600","url":null,"abstract":"Objective: Pyometra is a rare but serious condition, particularly in postmenopausal women. While commonly linked to postpartum or post-surgical complications, spontaneous pyometra may also be associated with underlying gynecologic malignancies. We aim to examine the association between postmenopausal spontaneous pyometra (PMSP) and gynecologic cancers.Methods: A retrospective review of consecutive women admitted with pyometra between 2007 and 2023, at a university-affiliated tertiary medical center. Demographic and clinical data were reviewed. Women with pyometra and gynecologic cancer were compared with those without.Results: Of 231 admissions for pyometra, 47 women with PMSP were identified. The cohort was divided into a benign group (n=35, 74.4%) and malignancy group (n=12, 25.6%). Endometrial carcinoma (n=8, 67%) was the predominant malignancy, followed by cervical cancer (n=4, 33%). Although age, age at menopause, and parity showed no significant statistical differences between the groups, a higher body mass index was significantly associated with endometrial malignancy (P = 0.014). Postmenopausal bleeding as an accompanying symptom to pyometra was also more common in the malignancy group (P=0.001). The prevalence of PMSP was 1.1% for endometrial cancer and 2.2% for cervical cancer.Conclusions: PMSP is significantly associated with gynecologic malignancies, particularly endometrial and cervical cancers. Notably, women with endometrial malignancy had a higher BMI and were more likely to present with accompanying postmenopausal bleeding. These findings suggest that in postmenopausal women presenting with spontaneous pyometra, clinicians should maintain a high index of suspicion for malignancy. Early identification and appropriate management are crucial to improving patient outcomes.","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacologic options for the treatment of overweight and obesity. 治疗超重和肥胖的药物选择。

IF 2.8 3区医学

Menopause: The Journal of The North American Menopause Society Pub Date : 2025-06-24 DOI: 10.1097/GME.0000000000002573

Maria Daniela Hurtado Andrade

引用次数: 0

Exploring Mirena use in association with symptoms at midlife. 探索更年期与中年症状的关系

IF 2.8 3区医学

Menopause: The Journal of The North American Menopause Society Pub Date : 2025-06-17 DOI: 10.1097/GME.0000000000002578

Ava Warner, Sofiya Shreyer, Daniel E Brown, Lynnette L Sievert

{"title":"Exploring Mirena use in association with symptoms at midlife.","authors":"Ava Warner, Sofiya Shreyer, Daniel E Brown, Lynnette L Sievert","doi":"10.1097/GME.0000000000002578","DOIUrl":"https://doi.org/10.1097/GME.0000000000002578","url":null,"abstract":"Objective: The Mirena IUD is prescribed for the treatment of heavy menstrual bleeding and contraception. The purpose of this study was to examine the use of Mirena in relation to vasomotor, psychological, musculoskeletal, and sexual symptoms and to see whether the use of a Mirena IUD increased the likelihood of experiencing symptoms during the menopause transition.Methods: Data were drawn from a study of brown adipose tissue and hot flashes (n=274). Participants were aged 45-55, living in western Massachusetts. Twenty-three (8%) were using Mirena at the time of the interview. Nine symptoms were examined individually and after grouping into clusters by factor analysis. Following bivariate analyses, logistic regressions were used to examine the use of Mirena in relation to hot flashes, night sweats, leg cramps, aches/stiffness, backaches, and depressed mood, while adjusting for age and BMI. We did not adjust for menopausal status because the use of Mirena influenced menstruation, which inhibited accurate estimation of menopausal status.Results: There were no significant relationships between the use of Mirena and symptoms at midlife. Higher BMI increased the likelihood of hot flashes, night sweats, and leg cramps.Conclusions: These findings suggest that the use of the Mirena IUD, whether for treatment of heavy blood loss, contraceptive control, or for the management of other menstrual symptoms, is unlikely to have adverse effects on symptom experience in midlife.","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sexual minority women and symptoms at midlife. 性少数女性和中年症状。

IF 2.8 3区医学

Menopause: The Journal of The North American Menopause Society Pub Date : 2025-06-17 DOI: 10.1097/GME.0000000000002580

Lynnette L Sievert, Krystal Kittle, Nicole VanKim, Raeann Leblanc, Sofiya Shreyer, Daniel E Brown, Aline Gubrium

{"title":"Sexual minority women and symptoms at midlife.","authors":"Lynnette L Sievert, Krystal Kittle, Nicole VanKim, Raeann Leblanc, Sofiya Shreyer, Daniel E Brown, Aline Gubrium","doi":"10.1097/GME.0000000000002580","DOIUrl":"https://doi.org/10.1097/GME.0000000000002580","url":null,"abstract":"Objective: The purpose of this study was to examine vasomotor, somatic, emotional, and sexual symptoms in relation to sexual orientation.Methods: Women aged 45 to 55 (n=274) from western Massachusetts participated in face-to-face interviews and anthropometric measures. Participants were asked, \"Do you think of yourself as lesbian or gay; straight, that is not lesbian or gay; bisexual; something else; or don't know?\" Bivariate analyses assessed sexual orientation in relation to each of 11 symptoms. Logistic regressions were carried out for aches/stiffness in joints, irritability, vaginal dryness, and loss of sexual desire in relation to sexual orientation, adjusting for menopausal status, partnership status, and body mass index (BMI).Results: Participants described themselves as \"straight\" (81%), \"lesbian or gay\" (7%), \"bisexual\" (7%), or other (5%). Partnership status, economic comfort, perceived stress, BMI, smoking habits, and parity did not differ by sexual orientation, but heterosexual women were more likely to drink alcohol. Compared with heterosexual women, sexual minority women had lower odds of reporting a loss of sexual desire (OR: 0.46, 95% CI: 0.24-0.89), and unpartnered women had a lower likelihood of reporting a loss of sexual desire (OR: 0.42, 95% CI: 0.24-0.73) compared with women with partners. Sexual minority women had higher odds of aches/stiffness in joints (OR: 3.78, 95% CI: 1.35-10.59).Conclusions: Sexual minority women had lower odds of reporting a loss of sexual desire but were more likely to report aches/stiffness in joints. More research is needed to better understand factors contributing to the menopause experiences of sexual minority populations.","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0