Ulrik Stervbo, Moritz Anft, Krystallenia Paniskaki, Arturo Blazquez-Navarro, Adrian Doevelaar, Sarah Skrzypczyk, Eva Kohut, Julia Kurek, Patrizia Wehler, Sviatlana Kaliszczyk, Kamil Rosiewicz, Felix S Seibert, Bodo Hölzer, Constantin J Thieme, Toralf Roch, Margarethe Justine Konik, Marc Moritz Berger, Thorsten Brenner, Uwe Kölsch, Michael Adamzik, Michael Schmueck-Henneresse, Carmen Scheibenbogen, Sebastian Dolff, Ulf Dittmer, Oliver Witzke, Timm H Westhoff, Nina Babel
{"title":"Acute COVID-19 is associated with altered CD8 T-cells indicative of impaired ability to control Epstein-Barr virus reactivation.","authors":"Ulrik Stervbo, Moritz Anft, Krystallenia Paniskaki, Arturo Blazquez-Navarro, Adrian Doevelaar, Sarah Skrzypczyk, Eva Kohut, Julia Kurek, Patrizia Wehler, Sviatlana Kaliszczyk, Kamil Rosiewicz, Felix S Seibert, Bodo Hölzer, Constantin J Thieme, Toralf Roch, Margarethe Justine Konik, Marc Moritz Berger, Thorsten Brenner, Uwe Kölsch, Michael Adamzik, Michael Schmueck-Henneresse, Carmen Scheibenbogen, Sebastian Dolff, Ulf Dittmer, Oliver Witzke, Timm H Westhoff, Nina Babel","doi":"10.1007/s00430-026-00873-3","DOIUrl":"10.1007/s00430-026-00873-3","url":null,"abstract":"","PeriodicalId":18369,"journal":{"name":"Medical Microbiology and Immunology","volume":"215 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13092548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147723273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vladimir Talayev, Dmitry Novikov, Elena Kurkova, Irina Zaichenko, Maria Svetlova, Olga Babaykina, Anna-Maria Zharova, Vladislav Lapin, Dmitry Melentev, Nadezhda Novikova, Alexander Kashnikov, Viktor Novikov
{"title":"Response of dendritic cells and T cells to virus-like particles formed from norovirus viral protein-1 (VP1N) or chimeric molecules containing a fragment of VP1N and polypeptides of echovirus 30.","authors":"Vladimir Talayev, Dmitry Novikov, Elena Kurkova, Irina Zaichenko, Maria Svetlova, Olga Babaykina, Anna-Maria Zharova, Vladislav Lapin, Dmitry Melentev, Nadezhda Novikova, Alexander Kashnikov, Viktor Novikov","doi":"10.1007/s00430-026-00874-2","DOIUrl":"https://doi.org/10.1007/s00430-026-00874-2","url":null,"abstract":"","PeriodicalId":18369,"journal":{"name":"Medical Microbiology and Immunology","volume":"215 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147633900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Henrique Fernando Lopes-Araujo, Wlisses Henrique Veloso Carvalho-Silva, José Leandro Andrade-Santos, Maria Carolina Santos Guedes, Fabrício Oliveira Souto, Luiz Cláudio Arraes De Alencar, Isadora Bandeira De Luna Paes Barreto Brennand, Thayana Karinne Oliveira Monteiro, Kleyverson Feliciano-Santos, José Artur Bogo Chies, Rafael Lima Guimarães
{"title":"CCR5Δ32 polymorphism is associated with increased central memory CD4+ T cells in virologically suppressed people living with HIV on antiretroviral therapy.","authors":"Henrique Fernando Lopes-Araujo, Wlisses Henrique Veloso Carvalho-Silva, José Leandro Andrade-Santos, Maria Carolina Santos Guedes, Fabrício Oliveira Souto, Luiz Cláudio Arraes De Alencar, Isadora Bandeira De Luna Paes Barreto Brennand, Thayana Karinne Oliveira Monteiro, Kleyverson Feliciano-Santos, José Artur Bogo Chies, Rafael Lima Guimarães","doi":"10.1007/s00430-026-00872-4","DOIUrl":"10.1007/s00430-026-00872-4","url":null,"abstract":"","PeriodicalId":18369,"journal":{"name":"Medical Microbiology and Immunology","volume":"215 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13053376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147623277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joana Saraiva, Joana N Bugalhão, Teresa Carvalho, Zach Hensel, Alvaro Crevenna, L Jaime Mota, Irina S Franco
{"title":"The small GTPase Rab5 inhibits actin polymerization mediated by the Legionella pneumophila effector VipA.","authors":"Joana Saraiva, Joana N Bugalhão, Teresa Carvalho, Zach Hensel, Alvaro Crevenna, L Jaime Mota, Irina S Franco","doi":"10.1007/s00430-026-00871-5","DOIUrl":"10.1007/s00430-026-00871-5","url":null,"abstract":"","PeriodicalId":18369,"journal":{"name":"Medical Microbiology and Immunology","volume":"215 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13046614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147593107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rima Alsalihi, Kerstin Andersson, Alaitz Aranburu, Christine Lingblom, Linda Wass, Catharina Lewerin, Marie Edvinsson, Andreas Mårtensson, Kenneth Nilsson, Elisabet Skoog, Anna-Carin Lundell, Beatrice Bergström, Anna Grankvist, Christine Wennerås
{"title":"Detection of human antibody responses to tick-borne Neoehrlichia mikurensis.","authors":"Rima Alsalihi, Kerstin Andersson, Alaitz Aranburu, Christine Lingblom, Linda Wass, Catharina Lewerin, Marie Edvinsson, Andreas Mårtensson, Kenneth Nilsson, Elisabet Skoog, Anna-Carin Lundell, Beatrice Bergström, Anna Grankvist, Christine Wennerås","doi":"10.1007/s00430-026-00869-z","DOIUrl":"10.1007/s00430-026-00869-z","url":null,"abstract":"<p><p>Tick-borne Neoehrlichia mikurensis is the cause of neoehrlichiosis, an infectious disease that features fever and vascular events. Compromised B-cell immunity is a risk factor for severe neoehrlichiosis, indicating the importance of antibodies in host defense. The development of serological assays has been hampered by the difficulty of culturing these intracellular bacteria. Here we present the first serological test for N. mikurensis, an ELISA for human IgM and IgG antibody responses to a P44/Msp2 protein of N. mikurensis. Serum or plasma from immunocompetent (n = 44) and immunosuppressed (n = 60) Swedish adults infected with N. mikurensis, with and without symptoms, were analyzed and compared with blood samples from non-infected immunocompetent individuals (n = 17). Sera from non-infected children (n = 23) and plasma from cord blood (n = 10) were also analyzed. Immunocompetent neoehrlichiosis adults had higher IgM and IgG antibody levels compared with immunosuppressed neoehrlichiosis patients treated with the B-cell suppressive agent rituximab. There were no significant differences in the IgM or IgG antibody levels between immunocompetent individuals with symptomatic versus asymptomatic N. mikurensis infection. Sera from healthy children contained high levels of IgM antibodies, despite no evidence of current infection with N. mikurensis nor previous exposure to tick bites as reflected by negative Borrelia serology. This IgM response was absent in cord blood plasma (n = 10), indicating it was not due to natural IgM antibodies. The high constitutional IgM antibody levels to N. mikurensis in children may explain why there have been no reports of pediatric neoehrlichiosis.</p>","PeriodicalId":18369,"journal":{"name":"Medical Microbiology and Immunology","volume":"215 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12982229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147444208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elsy Martínez-Gorgonio, Rosa Del Carmen Rocha-Gracia, Miguel Castañeda-Lucio, Margarita M P Arenas-Hernández, Miguel A Cevallos, Yolanda Sáenz, Patricia Lozano-Zarain
{"title":"Characterization of outer membrane vesicles from Acinetobacter haemolyticus and their role in the dissemination of carbapenem resistance.","authors":"Elsy Martínez-Gorgonio, Rosa Del Carmen Rocha-Gracia, Miguel Castañeda-Lucio, Margarita M P Arenas-Hernández, Miguel A Cevallos, Yolanda Sáenz, Patricia Lozano-Zarain","doi":"10.1007/s00430-026-00870-6","DOIUrl":"10.1007/s00430-026-00870-6","url":null,"abstract":"","PeriodicalId":18369,"journal":{"name":"Medical Microbiology and Immunology","volume":"215 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147307513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
