{"title":"Temporomandibular joint (TMJ) morphology in jaw deformity patients (class II and III) before and after surgical orthodontic treatment: a narrative review.","authors":"Koichiro Ueki, Karen Gomi, Kohara Riku, Yusuke Kurosawa, Kunio Yoshizawa, Akinori Moroi","doi":"10.1186/s40902-026-00512-0","DOIUrl":"https://doi.org/10.1186/s40902-026-00512-0","url":null,"abstract":"<p><p>Understanding changes in temporomandibular joint (TMJ) and ramus morphology in skeletal Class II and Class III jaw deformity patients before and after surgical orthodontic treatment is essential for achieving stable postoperative outcomes. Alterations in the positional relationship and morphology of the condyle, TMJ disc, and glenoid fossa can significantly influence postoperative occlusion and skeletal stability. Previous studies have demonstrated close associations among maxillofacial morphology, occlusion, and TMJ structure.In this narrative review, we summarize findings from our previous investigations regarding changes in TMJ morphology-including disc position, joint space, macroscopic morphology of the condyle and ramus, and computed tomography (CT) values-as well as considerations based on stress analysis in skeletal Class II and Class III deformities. These insights may contribute to a better understanding of anatomical characteristics of the TMJ in jaw deformity patients and may aid in predicting postoperative morphological changes.</p>","PeriodicalId":18357,"journal":{"name":"Maxillofacial Plastic and Reconstructive Surgery","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mostafa Gafar Ibrahim, Gamal Ali Swaify, Ibrahim Zaitoun, Ahmed Mohamed Medra, Ahmed Yehia Kosba, Mohamed Abdeldayem
{"title":"Template-guided digitally planned patient-specific implant augmentation eminoplasty for chronic recurrent temporomandibular joint dislocation: a prospective study.","authors":"Mostafa Gafar Ibrahim, Gamal Ali Swaify, Ibrahim Zaitoun, Ahmed Mohamed Medra, Ahmed Yehia Kosba, Mohamed Abdeldayem","doi":"10.1186/s40902-026-00508-w","DOIUrl":"10.1186/s40902-026-00508-w","url":null,"abstract":"<p><strong>Background: </strong>Surgical options for chronic recurrent temporomandibular joint (TMJ) dislocation remain heterogeneous. Digitally planned patient-specific onlay augmentation may provide a reproducible mechanical stop while minimizing intraoperative guesswork.</p><p><strong>Methods: </strong>Eleven patients (> 16 years) with chronic recurrent TMJ dislocation/hypermobility (maximal incisal opening > 40 mm) underwent augmentation eminoplasty using a digitally planned patient-specific implant and CAD/CAM workflow. Clinical outcomes included pain (VAS 0-10) and maximal incisal opening (MIO) assessed preoperatively, at 2 weeks, and at 6 months; radiologic assessment included panoramic TMJ views and MSCT at 6 months.</p><p><strong>Results: </strong>The cohort was predominantly female (72.7%) with mean age 20.55 ± 4.08 years. Mean VAS pain decreased from 8.80±0.53 preoperatively to 8.07±0.73 at 2 weeks and 6.29±1.29 at 6 months (all pairwise comparisons p<0.001). Mouth opening decreased significantly after surgery and remained reduced at follow-up; there was no significant difference between 2-week and 6-month mouth opening (p=0.082). Two patients (18.2%) developed right-sided postoperative infection requiring implant removal. Clinical signs suggestive of infection were first recognized at approximately 3 weeks postoperatively and ultimately led to implant removal at around 2 months after failure of initial conservative treatment. No clinical recurrence of dislocation/open-lock was documented during the available 6-month follow-up.</p><p><strong>Conclusions: </strong>Digitally planned patient-specific onlay eminoplasty demonstrated short-term feasibility, reduction in pain, and controlled postoperative mouth opening; however, the observed infection rate and limited functional follow-up warrant cautious interpretation.\"</p>","PeriodicalId":18357,"journal":{"name":"Maxillofacial Plastic and Reconstructive Surgery","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rawan Affat Alanazi, Abdulaziz Almutairi, Sarah Almuwarraee, Sarah Amuatrafi, Shaden Bahatheq, Ahmed Saad Al Zomia, Raghad Alotaibi, Rudaynah Haddad, Meshael Bajunaid, Rund Almohaish, Jana Batarji, Zainab Alasfour, Shaikha Aleid
{"title":"Ophthalmic complications following maxillofacial and midface fractures: a systematic review\".","authors":"Rawan Affat Alanazi, Abdulaziz Almutairi, Sarah Almuwarraee, Sarah Amuatrafi, Shaden Bahatheq, Ahmed Saad Al Zomia, Raghad Alotaibi, Rudaynah Haddad, Meshael Bajunaid, Rund Almohaish, Jana Batarji, Zainab Alasfour, Shaikha Aleid","doi":"10.1186/s40902-025-00498-1","DOIUrl":"https://doi.org/10.1186/s40902-025-00498-1","url":null,"abstract":"<p><p>Maxillofacial fractures can lead to significant ophthalmic complications, affecting patient outcomes. This systematic review synthesizes current evidence regarding the incidence, causes, and types of ocular injuries associated with facial fractures, while evaluating inter-study variability and risk of bias. Following the PRISMA guidelines, a comprehensive search of PubMed, Cochrane, and Web of Science databases was performed. Twenty-one studies, including 7,998 participants, met the inclusion criteria. Among them, 3,693 patients presented with ophthalmic complications after facial fractures. Orbital fractures were the most prevalent, with injuries primarily resulting from road traffic accidents and assaults. Subconjunctival hemorrhage was the most common ocular injury. Heterogeneity across studies was assessed descriptively due to the diversity of study designs and outcomes, while risk of bias was evaluated using adapted criteria for observational studies. The findings underscore the necessity for standardized diagnostic and reporting criteria to enable future quantitative synthesis and guide clinical protocols for early detection and management of ocular complications.</p>","PeriodicalId":18357,"journal":{"name":"Maxillofacial Plastic and Reconstructive Surgery","volume":"48 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13106098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Min-Seo Kim, Young-Hee Kim, Sang-Yoon Park, Hyung-Chan Lee, Tae-Yoon Park, Byoung-Eun Yang, Soo-Hwan Byun
{"title":"Delayed-onset chronic mandibular osteomyelitis following Lemierre's syndrome: a case report.","authors":"Min-Seo Kim, Young-Hee Kim, Sang-Yoon Park, Hyung-Chan Lee, Tae-Yoon Park, Byoung-Eun Yang, Soo-Hwan Byun","doi":"10.1186/s40902-026-00504-0","DOIUrl":"10.1186/s40902-026-00504-0","url":null,"abstract":"","PeriodicalId":18357,"journal":{"name":"Maxillofacial Plastic and Reconstructive Surgery","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13106101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147593128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pilvi Mäntynen, Juha Koivisto, Junnu Leikola, Touko Kaasalainen, Noemi Sipos, Arja Heliövaara, Jani Horelli, Jan Wolff, Niilo Lusila, Juho Suojanen
{"title":"Ultra-low-dose cone-beam CT for cleft and craniofacial deformity surgery: radiation reduction and clinical applicability.","authors":"Pilvi Mäntynen, Juha Koivisto, Junnu Leikola, Touko Kaasalainen, Noemi Sipos, Arja Heliövaara, Jani Horelli, Jan Wolff, Niilo Lusila, Juho Suojanen","doi":"10.1186/s40902-026-00505-z","DOIUrl":"10.1186/s40902-026-00505-z","url":null,"abstract":"","PeriodicalId":18357,"journal":{"name":"Maxillofacial Plastic and Reconstructive Surgery","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147355624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Monocyte chemoattractant protein-1 from a conditioned medium of bone marrow-derived mesenchymal stem cells promotes bone regeneration by enhancing macrophage phenotype polarization.","authors":"Kosuke Hashizume, Wataru Katagiri, Ryoko Takeuchi, Daisuke Suda, Tadaharu Kobayashi","doi":"10.1186/s40902-026-00503-1","DOIUrl":"10.1186/s40902-026-00503-1","url":null,"abstract":"<p><strong>Background: </strong>We have reported that the cytokines and chemokines contained in conditioned medium of human mesenchymal stem cells (MSC-CM), which were derived from bone marrow, promote bone regeneration. We recently reported macrophage phenotype polarization towards the anti-inflammatory M2 phenotype induced by MSC-CM and its potential to establish regenerative condition and assist subsequent bone regeneration. However, the specific factors in the MSC-CM responsible for this process remain unclear. Monocyte chemoattractant protein (MCP) -1, present in MSC-CM, promotes cell migration and activation of the monocyte-macrophage lineage; therefore, we hypothesized that MCP-1 is one of the key factors in MSC-CM-induced macrophage phenotype polarization. The effect of MCP-1 on MSC-CM-induced macrophage phenotype polarization and subsequent bone regeneration was investigated in this study.</p><p><strong>Methods: </strong>MCP-1 was depleted from MSC-CM (depMSC-CM) and used in subsequent experiments. Rat bone marrow macrophages were incubated in MSC-CM or depMSC-CM and expression of macrophage markers was examined in vitro. In addition, the effect of MSC-CM and depMSC-CM on bone regeneration and macrophage phenotype polarization were evaluated using rat calvaria defect model in vivo.</p><p><strong>Results: </strong>MSC-CM enhanced M2 macrophage marker expression in rat bone marrow macrophages compared to those treated with depMSC-CM in vitro. In addition, MSC-CM increased the number of M2 macrophage marker-positive cells in bone defects and enhanced subsequent bone regeneration in a rat calvaria bone defect model.</p><p><strong>Conclusions: </strong>MCP-1 seemed to be a one of the most contributing factors in MSC-CM-induced macrophage phenotypic polarization and subsequent bone regeneration.</p>","PeriodicalId":18357,"journal":{"name":"Maxillofacial Plastic and Reconstructive Surgery","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12946564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147284163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of impacted mandibular third molar surgery performed with piezosurgery and conventional systems on postoperative sequelae and quality of life: a randomized controlled trial.","authors":"Izzet Acikan, Aykut Can Balkanlioglu","doi":"10.1186/s40902-026-00502-2","DOIUrl":"10.1186/s40902-026-00502-2","url":null,"abstract":"","PeriodicalId":18357,"journal":{"name":"Maxillofacial Plastic and Reconstructive Surgery","volume":"48 1","pages":"3"},"PeriodicalIF":2.8,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12858685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146086225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}