{"title":"MODELLING OF HILLSLOPE STORAGE UNDER TEMPORALLY VARIED RAINFALL RECHARGE","authors":"P. Hsieh, Tzu-Ting Huang","doi":"10.1051/mmnp/2023009","DOIUrl":"https://doi.org/10.1051/mmnp/2023009","url":null,"abstract":"Water storage inside hillslopes is a crucial issue of environment and water resources. This study separately built a numerical model and an analytical model employing a hillslope-storage equation to simulate the water storage in a sloping aquifer response to recharge. The variable width of hillslope was hypothetically represented by an exponential function to categorize the hillslope into three types: uniform, convergent, and divergent. An integral transform technique was introduced to derive the analytical solution whereas a finite difference method was employed for the numerical modelling. As a result, under the same scenario a gap existed between the two solutions to distinct forms of the water storage equation, and the gap decreases with a falling recharge rate for convergent hillslopes. Moreover, all outflows gradually approached one value based on different hillslopes under the same accumulative recharge amount for six typical rainfall recharge patterns. Particularly, while the recharge stops, the outflow decreases and then mildly rises for a long time for convergent hillslope because of the slow water release near the upstream boundary where the storage water is relatively abundant due to the widest width.","PeriodicalId":18285,"journal":{"name":"Mathematical Modelling of Natural Phenomena","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44313701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bjarke Spangsberg Bak, Morten Andersen, J. Ottesen, Jesper Schmidt Hansen
{"title":"How do cell crowding and starvation affect avascular tumor growth of the EMT6/Ro tumor?","authors":"Bjarke Spangsberg Bak, Morten Andersen, J. Ottesen, Jesper Schmidt Hansen","doi":"10.1051/mmnp/2023007","DOIUrl":"https://doi.org/10.1051/mmnp/2023007","url":null,"abstract":"Here we re-examine experimental in vitro data for the EMT6/Ro tumor volume and viable rim thickness. This shows that the growth speed is constant in time, and independent of nutrient concentration at large concentrations, but that the viable rim thickness increases in this high concentration regime. We then present a simple mechanistic reaction-diffusion equation that includes crowding and starvation effects, and show that the model qualitatively captures the experimental observations. Moreover, the model predicts that the cancer cell concentration is characterised by a wave pulse (soliton), and the pulse shape is explored through zero’th order perturbation analysis corresponding to large wave speeds. It is shown that this zero’th order term is dominant for the experimental condition, further indicating that the non-linear reaction governs the pulse characteristic shape. Finally, at low nutrient concentrations we find that the front is a pulled-front, that is, the growth speed is determined by the cell multiplication at the wave front edge in accordance with earlier modelling approaches.","PeriodicalId":18285,"journal":{"name":"Mathematical Modelling of Natural Phenomena","volume":"1 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42480966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nader El Khatib, Amine Ghorbel, Agatha Joumaa, Mamdouh Zaydan
{"title":"Traveling solutions for a multi-anticipative car-following traffic model","authors":"Nader El Khatib, Amine Ghorbel, Agatha Joumaa, Mamdouh Zaydan","doi":"10.1051/mmnp/2023006","DOIUrl":"https://doi.org/10.1051/mmnp/2023006","url":null,"abstract":"In this paper, we consider a steady state multi-anticipative traffic model and we provide necessarily and sufficient conditions for the existence of traveling solutions. In our work, the word \"traveling\" means that the distance between two consecutive vehicles travels continuously between two different states. As application to our result, we show that taking a strictly concave optimal velocity, we can construct a traveling solution such that the distance between two vehicles decreases. The existence, uniqueness and the study of the asymptotic behavior of such solutions is done at the level of the Hamilton-Jacobi equation.","PeriodicalId":18285,"journal":{"name":"Mathematical Modelling of Natural Phenomena","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44366224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Weirui Lei, Ji-wen Hu, Yaxian Xie, Can Liu, Xuekun Chen
{"title":"Mathematical Modelling of the Effects of Statins on the Growth of Necrotic Core in Atherosclerotic Plaque","authors":"Weirui Lei, Ji-wen Hu, Yaxian Xie, Can Liu, Xuekun Chen","doi":"10.1051/mmnp/2023005","DOIUrl":"https://doi.org/10.1051/mmnp/2023005","url":null,"abstract":"A large necrotic core increases the risk of atherosclerotic plaque instability. Statins can delay the growth of necrotic core in plaques, but the kinetic mechanism of statins in slowing down the necrotic core has not yet been addressed in detail. In this paper, a mathematical model is governed by a system of advection-diffusion-reaction equations coupling of the porous nature of vessel wall is established and applied to illustrate the plaque growth with lipid-rich necrotic core (LRNC) with and without statins using finite element method. We study the influence of LRNC plaque growth for different drug concentrations at different time intervals. The results showed that the drug use at different time points has a significant impact on the treatment efficacy. Compared with short-term, low-dose treatment, early statin treatment with high dose showed more pronounced effects on reducing the low-density lipoprotein (LDL) cholesterol, decreasing the volume of necrotic core, changing the characteristics of plaques, and improving the plaque stability. The model is validated by comparing with the clinical data, and may be used to predict the progression of LRNC plaque and the effects of statin therapy.","PeriodicalId":18285,"journal":{"name":"Mathematical Modelling of Natural Phenomena","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44110722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhong Luo, Zijian Liu, Yuanshun Tan, Jin Yang, Huanhuan Qiu
{"title":"Threshold Behavior of an Age-structured Tumor Immune Model","authors":"Zhong Luo, Zijian Liu, Yuanshun Tan, Jin Yang, Huanhuan Qiu","doi":"10.1051/mmnp/2023001","DOIUrl":"https://doi.org/10.1051/mmnp/2023001","url":null,"abstract":"In this paper, we present and analyze an age-structured tumor immune model. Based on the fact that tumor cells of different ages tend to exhibit different physiological behaviors, we consider the age structure of tumor cells, age-based proliferation function and age-dependent death function in the model. The threshold $mathfrak{R}_{0}$ for the existence of tumor-free steady state is derived. It is found that if $mathfrak{R}_{0}<1$, the tumor-free steady state is not only locally stable but also globally stable. Moreover, numerical simulation shows that the threshold $mathfrak{R}_{0}$ may be regarded as an index to reflect the ability of ``tumor immune surveillance\", ie, the smaller the $mathfrak{R}_{0}$, the better the ability of tumor immune surveillance. If $mathfrak{R}_{0}>1$, it is proved that the tumor steady state is existent and uniformly persistent. The local stability of the tumor steady state is investigated under some further conditions besides $mathfrak{R}_{0}>1$. In the end, we estimate the system parameters, verify the theoretical results and analyze some system parameters' sensitivities.","PeriodicalId":18285,"journal":{"name":"Mathematical Modelling of Natural Phenomena","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48141211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of connecting sites in the environment of a harvested population","authors":"R. Bravo de la Parra, J. Poggiale, P. Auger","doi":"10.1051/mmnp/2023004","DOIUrl":"https://doi.org/10.1051/mmnp/2023004","url":null,"abstract":"This work presents a model of a harvested population in a multisite environment. Locally it has the shape of the Gordon-Schaefer model. This model gives rise, placing us in the case of a fishery, to an equilibrium of the stock and the fishing effort and, therefore, of the yield that is obtained per unit of time. Considering that the management of the fishery can act on the fishing costs, the yield is optimized as a function of the cost.\u0000The objective of the work is to compare the maximum obtained yield in two extreme cases: unconnected sites and connected sites with rapid movements of both the stock and the fishing effort. The analysis of the model, first in an environment with two sites and later with any number of them, makes it possible to establish the conditions for one of the two cases to be more favorable from the point of view of the yield. In this way, it is proposed towards which of the two compared cases management should be directed.","PeriodicalId":18285,"journal":{"name":"Mathematical Modelling of Natural Phenomena","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49407569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"FORECAST ANALYSIS AND SLIDING MODE CONTROL ON A STOCHASTIC\u0000\u0000EPIDEMIC MODEL WITH ALERTNESS AND VACCINATION","authors":"Yue Zhang, Xiju Wu","doi":"10.1051/mmnp/2023003","DOIUrl":"https://doi.org/10.1051/mmnp/2023003","url":null,"abstract":"In this paper, a stochastic SEIR epidemic model is studied with alertness and vaccination. The goal is to stabilize the infectious disease system quickly. The dynamic behavior of the model is analyzed and an integral sliding mode controller with distributed compensation is designed. By using Lyapunov function method, the sufficient conditions for the existence and uniqueness of global positive solutions and the existence of ergodic stationary distributions are obtained. The stochastic center manifold and stochastic average method are used to simplify the system into a one-dimensional Markov diffusion process. The stochastic stability and Hopf bifurcation are analyzed using singular boundary theory. An integral sliding mode controller with non-parallel distributed compensation is designed by linear matrix inequality (LMI) method, which realizes the stability of system and prevents the outbreak of epidemic disease. The correction of theoretical analysis and the effectiveness of controller are validated using numerical simulation performed in MATLAB/Simulink.","PeriodicalId":18285,"journal":{"name":"Mathematical Modelling of Natural Phenomena","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48606210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}