发布求助
文献互助 智能选刊 最新文献

Mammalian Genome最新文献

筛选
英文 中文
Retraction Note: Circ_0069718 promotes the progression of breast cancer by up-regulating NFIB through sequestering miR-590-5p. 注:Circ_0069718通过隔离miR-590-5p上调NFIB，促进乳腺癌的进展。
IF 2.5 4区 生物学
Mammalian Genome Pub Date : 2023-09-01 DOI: 10.1007/s00335-023-10001-8
Yongsheng Zhao, Xiaocha Ma, Weihua Shi
{"title":"Retraction Note: Circ_0069718 promotes the progression of breast cancer by up-regulating NFIB through sequestering miR-590-5p.","authors":"Yongsheng Zhao, Xiaocha Ma, Weihua Shi","doi":"10.1007/s00335-023-10001-8","DOIUrl":"https://doi.org/10.1007/s00335-023-10001-8","url":null,"abstract":"","PeriodicalId":18259,"journal":{"name":"Mammalian Genome","volume":"34 Suppl 1","pages":"2"},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10027318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Essential genes: a cross-species perspective. 基本基因：跨物种视角。
IF 2.5 4区 生物学
Mammalian Genome Pub Date : 2023-09-01 Epub Date: 2023-03-10 DOI: 10.1007/s00335-023-09984-1
Pilar Cacheiro, Damian Smedley
{"title":"Essential genes: a cross-species perspective.","authors":"Pilar Cacheiro, Damian Smedley","doi":"10.1007/s00335-023-09984-1","DOIUrl":"10.1007/s00335-023-09984-1","url":null,"abstract":"<p><p>Protein coding genes exhibit different degrees of intolerance to loss-of-function variation. The most intolerant genes, whose function is essential for cell or/and organism survival, inform on fundamental biological processes related to cell proliferation and organism development and provide a window on the molecular mechanisms of human disease. Here we present a brief overview of the resources and knowledge gathered around gene essentiality, from cancer cell lines to model organisms to human development. We outline the implications of using different sources of evidence and definitions to determine which genes are essential and highlight how information on the essentiality status of a gene can inform novel disease gene discovery and therapeutic target identification.</p>","PeriodicalId":18259,"journal":{"name":"Mammalian Genome","volume":"34 3","pages":"357-363"},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9954473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Ontology of Biological Attributes (OBA)-computational traits for the life sciences. 生物属性本体（OBA）--生命科学的计算特征。
IF 2.5 4区 生物学
Mammalian Genome Pub Date : 2023-09-01 Epub Date: 2023-04-19 DOI: 10.1007/s00335-023-09992-1
Ray Stefancsik, James P Balhoff, Meghan A Balk, Robyn L Ball, Susan M Bello, Anita R Caron, Elissa J Chesler, Vinicius de Souza, Sarah Gehrke, Melissa Haendel, Laura W Harris, Nomi L Harris, Arwa Ibrahim, Sebastian Koehler, Nicolas Matentzoglu, Julie A McMurry, Christopher J Mungall, Monica C Munoz-Torres, Tim Putman, Peter Robinson, Damian Smedley, Elliot Sollis, Anne E Thessen, Nicole Vasilevsky, David O Walton, David Osumi-Sutherland
{"title":"The Ontology of Biological Attributes (OBA)-computational traits for the life sciences.","authors":"Ray Stefancsik, James P Balhoff, Meghan A Balk, Robyn L Ball, Susan M Bello, Anita R Caron, Elissa J Chesler, Vinicius de Souza, Sarah Gehrke, Melissa Haendel, Laura W Harris, Nomi L Harris, Arwa Ibrahim, Sebastian Koehler, Nicolas Matentzoglu, Julie A McMurry, Christopher J Mungall, Monica C Munoz-Torres, Tim Putman, Peter Robinson, Damian Smedley, Elliot Sollis, Anne E Thessen, Nicole Vasilevsky, David O Walton, David Osumi-Sutherland","doi":"10.1007/s00335-023-09992-1","DOIUrl":"10.1007/s00335-023-09992-1","url":null,"abstract":"<p><p>Existing phenotype ontologies were originally developed to represent phenotypes that manifest as a character state in relation to a wild-type or other reference. However, these do not include the phenotypic trait or attribute categories required for the annotation of genome-wide association studies (GWAS), Quantitative Trait Loci (QTL) mappings or any population-focussed measurable trait data. The integration of trait and biological attribute information with an ever increasing body of chemical, environmental and biological data greatly facilitates computational analyses and it is also highly relevant to biomedical and clinical applications. The Ontology of Biological Attributes (OBA) is a formalised, species-independent collection of interoperable phenotypic trait categories that is intended to fulfil a data integration role. OBA is a standardised representational framework for observable attributes that are characteristics of biological entities, organisms, or parts of organisms. OBA has a modular design which provides several benefits for users and data integrators, including an automated and meaningful classification of trait terms computed on the basis of logical inferences drawn from domain-specific ontologies for cells, anatomical and other relevant entities. The logical axioms in OBA also provide a previously missing bridge that can computationally link Mendelian phenotypes with GWAS and quantitative traits. The term components in OBA provide semantic links and enable knowledge and data integration across specialised research community boundaries, thereby breaking silos.</p>","PeriodicalId":18259,"journal":{"name":"Mammalian Genome","volume":"34 3","pages":"364-378"},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10276689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction Note: MiR-519d-3p enhances the sensitivity of non-small-cell lung cancer to tyrosine kinase inhibitors. 注:MiR-519d-3p增强了非小细胞肺癌对酪氨酸激酶抑制剂的敏感性。
IF 2.5 4区 生物学
Mammalian Genome Pub Date : 2023-09-01 DOI: 10.1007/s00335-023-10003-6
Qiang Zhen, Yaxiao Zhang, Lina Gao, Renfeng Wang, Weiwei Chu, Xiaojian Zhao, Zhe Li, Huixian Li, Bing Zhang, Baolei Lv, Jiabao Liu
{"title":"Retraction Note: MiR-519d-3p enhances the sensitivity of non-small-cell lung cancer to tyrosine kinase inhibitors.","authors":"Qiang Zhen,&nbsp;Yaxiao Zhang,&nbsp;Lina Gao,&nbsp;Renfeng Wang,&nbsp;Weiwei Chu,&nbsp;Xiaojian Zhao,&nbsp;Zhe Li,&nbsp;Huixian Li,&nbsp;Bing Zhang,&nbsp;Baolei Lv,&nbsp;Jiabao Liu","doi":"10.1007/s00335-023-10003-6","DOIUrl":"https://doi.org/10.1007/s00335-023-10003-6","url":null,"abstract":"","PeriodicalId":18259,"journal":{"name":"Mammalian Genome","volume":"34 Suppl 1","pages":"4"},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10380488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A consensus score to combine inferences from multiple centres. 将多个中心的推论结合起来的共识得分。
IF 2.5 4区 生物学
Mammalian Genome Pub Date : 2023-09-01 Epub Date: 2023-05-08 DOI: 10.1007/s00335-023-09993-0
Hamed Haselimashhadi, Kolawole Babalola, Robert Wilson, Tudor Groza, Violeta Muñoz-Fuentes
{"title":"A consensus score to combine inferences from multiple centres.","authors":"Hamed Haselimashhadi, Kolawole Babalola, Robert Wilson, Tudor Groza, Violeta Muñoz-Fuentes","doi":"10.1007/s00335-023-09993-0","DOIUrl":"10.1007/s00335-023-09993-0","url":null,"abstract":"<p><p>Experiments in which data are collected by multiple independent resources, including multicentre data, different laboratories within the same centre or with different operators, are challenging in design, data collection and interpretation. Indeed, inconsistent results across the resources are possible. In this paper, we propose a statistical solution for the problem of multi-resource consensus inferences when statistical results from different resources show variation in magnitude, directionality, and significance. Our proposed method allows combining the corrected p-values, effect sizes and the total number of centres into a global consensus score. We apply this method to obtain a consensus score for data collected by the International Mouse Phenotyping Consortium (IMPC) across 11 centres. We show the application of this method to detect sexual dimorphism in haematological data and discuss the suitability of the methodology.</p>","PeriodicalId":18259,"journal":{"name":"Mammalian Genome","volume":"34 3","pages":"379-388"},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10662292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bridging mouse and human anatomies; a knowledge-based approach to comparative anatomy for disease model phenotyping. 连接小鼠和人体解剖;以知识为基础的方法来比较解剖学疾病模型表型。
IF 2.5 4区 生物学
Mammalian Genome Pub Date : 2023-09-01 DOI: 10.1007/s00335-023-10005-4
Jesús Ruberte, Paul N Schofield, John P Sundberg, Alfonso Rodriguez-Baeza, Ana Carretero, Colin McKerlie
{"title":"Bridging mouse and human anatomies; a knowledge-based approach to comparative anatomy for disease model phenotyping.","authors":"Jesús Ruberte,&nbsp;Paul N Schofield,&nbsp;John P Sundberg,&nbsp;Alfonso Rodriguez-Baeza,&nbsp;Ana Carretero,&nbsp;Colin McKerlie","doi":"10.1007/s00335-023-10005-4","DOIUrl":"https://doi.org/10.1007/s00335-023-10005-4","url":null,"abstract":"<p><p>The laboratory mouse is the foremost mammalian model used for studying human diseases and is closely anatomically related to humans. Whilst knowledge about human anatomy has been collected throughout the history of mankind, the first comprehensive study of the mouse anatomy was published less than 60 years ago. This has been followed by the more recent publication of several books and resources on mouse anatomy. Nevertheless, to date, our understanding and knowledge of mouse anatomy is far from being at the same level as that of humans. In addition, the alignment between current mouse and human anatomy nomenclatures is far from being as developed as those existing between other species, such as domestic animals and humans. To close this gap, more in depth mouse anatomical research is needed and it will be necessary to extent and refine the current vocabulary of mouse anatomical terms.</p>","PeriodicalId":18259,"journal":{"name":"Mammalian Genome","volume":"34 3","pages":"389-407"},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9902442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Retraction Note: LncRNA TLR8-AS1 suppresses miR-34a maturation in hepatocellular carcinoma to suppress cell proliferation and migration. 注:LncRNA TLR8-AS1在肝细胞癌中抑制miR-34a成熟，抑制细胞增殖和迁移。
IF 2.5 4区 生物学
Mammalian Genome Pub Date : 2023-09-01 DOI: 10.1007/s00335-023-10004-5
Xin Shi, Hu Chen, Wei Wang, Bingzheng Yan, Zhikai Yang, Jingpo Zhang
{"title":"Retraction Note: LncRNA TLR8-AS1 suppresses miR-34a maturation in hepatocellular carcinoma to suppress cell proliferation and migration.","authors":"Xin Shi,&nbsp;Hu Chen,&nbsp;Wei Wang,&nbsp;Bingzheng Yan,&nbsp;Zhikai Yang,&nbsp;Jingpo Zhang","doi":"10.1007/s00335-023-10004-5","DOIUrl":"https://doi.org/10.1007/s00335-023-10004-5","url":null,"abstract":"","PeriodicalId":18259,"journal":{"name":"Mammalian Genome","volume":"34 Suppl 1","pages":"5"},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10025214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
INFRAFRONTIER: mouse model resources for modelling human diseases. INFRAFRONTIER:用于人类疾病建模的小鼠模型资源。
IF 2.5 4区 生物学
Mammalian Genome Pub Date : 2023-09-01 DOI: 10.1007/s00335-023-10010-7
Asrar Ali Khan, Gema Valera Vazquez, Montse Gustems, Rafaele Matteoni, Fei Song, Philipp Gormanns, Sabine Fessele, Michael Raess, Martin Hrabĕ de Angelis
{"title":"INFRAFRONTIER: mouse model resources for modelling human diseases.","authors":"Asrar Ali Khan,&nbsp;Gema Valera Vazquez,&nbsp;Montse Gustems,&nbsp;Rafaele Matteoni,&nbsp;Fei Song,&nbsp;Philipp Gormanns,&nbsp;Sabine Fessele,&nbsp;Michael Raess,&nbsp;Martin Hrabĕ de Angelis","doi":"10.1007/s00335-023-10010-7","DOIUrl":"https://doi.org/10.1007/s00335-023-10010-7","url":null,"abstract":"<p><p>Over the last decade, INFRAFRONTIER has positioned itself as a world-class Research Infrastructure for the generation, phenotyping, archiving, and distribution of mouse models in Europe. The INFRAFRONTIER network consists of 22 partners from 15 countries, and is continuously enhancing and broadening its portfolio of resources and services that are offered to the research community on a non-profit basis. By bringing together European rodent model expertise and providing valuable disease model services to the biomedical research community, INFRAFRONTIER strives to push the accessibility of cutting-edge human disease modelling technologies across the European research landscape. This article highlights the latest INFRAFRONTIER developments and informs the research community about its extensively utilised services, resources, and technical developments, specifically the intricacies of the INFRAFRONTIER database, use of Curated Disease Models, overview of the INFRAFRONTIER Cancer and Rare Disease resources, and information about its main state-of-the-art services.</p>","PeriodicalId":18259,"journal":{"name":"Mammalian Genome","volume":"34 3","pages":"408-417"},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9902960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Whole-genome sequencing and genomic analysis of Norduz goat (Capra hircus). 诺都士山羊(Capra hircus)全基因组测序及基因组分析。
IF 2.5 4区 生物学
Mammalian Genome Pub Date : 2023-09-01 DOI: 10.1007/s00335-023-09990-3
Mevlüt Arslan
{"title":"Whole-genome sequencing and genomic analysis of Norduz goat (Capra hircus).","authors":"Mevlüt Arslan","doi":"10.1007/s00335-023-09990-3","DOIUrl":"https://doi.org/10.1007/s00335-023-09990-3","url":null,"abstract":"<p><p>Artificial and natural selective breeding of goats has resulted in many different goat breeds all around the world. Norduz goat is one of these breeds, and it is a local goat breed of Turkey. The goats are favorable due to pre-weaning viability and reproduction values compared to the regional breeds. Development in sequencing technologies has let to understand huge genomic structures and complex phenotypes. Until now, such a comprehensive study has not been carried out to understand the genomic structure of the Norduz goats, yet. In the study, the next-generation sequencing was carried out to understand the genomic structure of Norduz goat. Real-time PCR was used to evaluate prominent CNVs in the Norduz goat individuals. Whole genome of the goat was constructed with an average of 33.1X coverage level. In the stringent filtering condition, 9,757,980 SNPs, 1,536,715 InDels, and 290 CNVs were detected in the Norduz goat genome. Functional analysis of high-impact SNP variations showed that the classical complement activation biological process was affected significantly in the goat. CNVs in the goat genome were found in genes related to defense against viruses, immune response, and cell membrane transporters. It was shown that GBP2, GBP5, and mammalian ortholog GBP1, which are INF-stimulated GTPases, were found to be high copy numbers in the goats. To conclude, genetic variations mainly in immunological response processes suggest that Norduz goat is an immunologically improved goat breed and natural selection could take an important role in the genetical improvements of the goats.</p>","PeriodicalId":18259,"journal":{"name":"Mammalian Genome","volume":"34 3","pages":"437-448"},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9954959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction Note: CircRNA_0043691 sponges miR-873-3p to promote metastasis of gastric cancer. 注:CircRNA_0043691海绵miR-873-3p促进胃癌转移。
IF 2.5 4区 生物学
Mammalian Genome Pub Date : 2023-09-01 DOI: 10.1007/s00335-023-10000-9
Yu Zhang, Gengyuan Hu, Zhenxing Zhang, Yuanming Jing, Feng Tao, Minfeng Ye
{"title":"Retraction Note: CircRNA_0043691 sponges miR-873-3p to promote metastasis of gastric cancer.","authors":"Yu Zhang,&nbsp;Gengyuan Hu,&nbsp;Zhenxing Zhang,&nbsp;Yuanming Jing,&nbsp;Feng Tao,&nbsp;Minfeng Ye","doi":"10.1007/s00335-023-10000-9","DOIUrl":"https://doi.org/10.1007/s00335-023-10000-9","url":null,"abstract":"","PeriodicalId":18259,"journal":{"name":"Mammalian Genome","volume":"34 Suppl 1","pages":"1"},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10015452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信