Duta Pharma Journal最新文献

{"title":"Gambaran Angka Lempeng Total Bakteri Pada Blemish Balm Cream Lokal Yang Beredar Di Kota Samarinda","authors":"Virjinia Dela Audita Rosihan, Tiara Dini Harlita, Sresta Azahra","doi":"10.47701/djp.v2i2.2432","DOIUrl":"https://doi.org/10.47701/djp.v2i2.2432","url":null,"abstract":"Kosmetik adalah kebutuhan sandang yang dianggap penting bagi sebagian masyarakat. Salah satunya ialah Blemish Balm Cream. BB Cream adalah kosmetik dekoratif yang mengandung bahan antioksidan dan tabir surya yang dipakai dalam jangka waktu lama dan akan ada peluang terjadinya kontaminasi bahkan akan semakin meningkat seiring dengan lamanya pemakaian. Penelitian ini bertujuan untuk mengetahui angka lempeng total bakteri Blemish Balm Cream lokal yang beredar di Kota Samarinda. Jenis penelitian yang digunakan adalah deskriptif dengan metode pemeriksaan Angka Lempeng Total (ALT). Analisis data penelitian menggunakan analisis univariate, sampel penelitian adalah 10 BB Cream merk lokal yang berada di Kota Samarinda dengan teknik sampling yaitu Total Sampling. Setiap 1 sampel ditimbang 10 gr dan dilakukan pemeriksaan angka lempeng total dengan pengenceran 101 sampai 104, sehingga setiap 1 sampel dilakukan 4 kali percobaan maka didapatkan 40 kali unit percobaan. Hasil penelitian didapatkan 80% sampel terkontaminasi bakteri dengan rata-rata ALT 1,0 × 102 CFU/mL. ALT tertinggi terdapat pada sampel BB01 yaitu 3,9 × 102 CFU/mL dan ALT terendah terdapat pada sampel BB10 yaitu 1,0 × 101 CFU/mL. Kesimpulan penelitian ini didapatkan 10 sampel (100%) memenuhi syarat yang telah ditetapkan oleh BPOM No. 12 Tahun 2019 dengan standar angka lempeng total < 103 koloni/mL.","PeriodicalId":182338,"journal":{"name":"Duta Pharma Journal","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131133316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analisis Pengaruh Tempat Penyimpanan Terhadap Kadar Protein Pada Ikan Patin","authors":"Safitri Indah Lestari, Ganea Qorry Aina, Dini Indriaty Yusran","doi":"10.47701/djp.v2i2.2434","DOIUrl":"https://doi.org/10.47701/djp.v2i2.2434","url":null,"abstract":"Ikan Patin (Pangasius sp.) merupakan ikan asli perairan Indonesia yang berhasil didomestikasikan. Daging ikan patin memiliki kandungan kalori dan protein yang cukup tinggi sehingga banyak dikonsumsi masyarakat Indonesia. Jumlah total produksi ikan patin sampai tahun 2014 adalah 403.132,80 ton dengan rata-rata peningkatan produksi tahunan sebesar 30,73%. Tujuan penelitian ini adalah untuk mengetahui gambaran tempat penyimpanan terhadap kadar protein pada ikan patin. Penelitian ini adalah penelitian deskriptif dengan metode Kjeldahl. Variabel pada penelitian ini adalah variabel tunggal yaitu kadar protein pada ikan patin yang dianalisa dengan variasi tempat yang berbeda. Sampel yang digunakan adalah daging fillet ikan patin segar. Berdasarkan hasil penelitian yang telah dilakukan, kadar protein tertinggi terdapat pada kulkas freezer dengan rata-rata sampel 1 sebesar 12,22%, sampel 2 sebesar 12,36%, dan sampel 3 sebesar 12,19% dan rata-rata kadar protein terendah terdapat pada kulkas bawah sampel 1 sebesar 10,04%, sampel 2 sebesar 10,06%, dan sampel 3 sebesar 9,97%. Dari hasil uji statistik terdapat pengaruh tempat penyimpanan terhadap kadar protein (F hitung > F tabel) denga nilai p < 0.05, dimana dari ketiga perlakuan tersebut penyimpanan di freezer memiliki nilai kadar protein tertinggi dibanding dengan penyimpanan di chiller dan kulkas bawah, dan perlakuan daging ikan yang tidak disimpan didalam kulkas (kontrol) adalah yang paling tinggi kadar proteinnya dibanding ketiga penyimpanan tersebut.","PeriodicalId":182338,"journal":{"name":"Duta Pharma Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132925334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PENETAPAN KADAR ALKALOID TOTAL DALAM EKSTRAK ETANOL BUNGA LAWANG (Illicium verum Hook.f) SECARA SPEKTROFOTOMETRI UV-VIS","authors":"Devia Danila, E. Rawar","doi":"10.47701/djp.v2i2.2409","DOIUrl":"https://doi.org/10.47701/djp.v2i2.2409","url":null,"abstract":"Bunga lawang (Illicium verum Hook.f) merupakan herba yang dimanfaatkan sebagai rempah makanan, wewangian, hingga insektisida. Namun belum ada penelitian mengenai kandungan alkaloid yang terdapat dalam ekstrak etanol bunga lawang (Illicium verum Hook.f). Penelitian ini bertujuan untuk menetapkan kadar alkaloid total dalam ekstrak etanol bunga lawang (Illicium verum Hook.f). Ekstrak etanol bunga lawang dibuat dari simplisia yang telah diserbukkan dengan ditambah etanol 96% lalu dimaserasi selama 2×24 jam di tempat yang terlindung dari sinar matahari langsung, kemudian disaring dan dipisahkan antara ampas dan filtrat sampel. Ampas yang diperoleh diekstraksi kembali dengan etanol yang baru dengan jumlah yang sama sebanyak 2 kali. Ekstrak etanol yang diperoleh kemudian dikumpulkan dalam wadah, dipekatkan dalam rotary evaporator dan cairan penyarinya diuapkan hingga diperoleh ekstrak etanol yang kental. Hasil penelitian menunjukkan bahwa kandungan alkaloid total dalam ekstrak etanol bunga lawang yaitu 35,04 mg/g dengan presentase 3,50 %.","PeriodicalId":182338,"journal":{"name":"Duta Pharma Journal","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134253028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL JANTUNG PISANG NANGKA, AMBON, DAN TANDUK (Musa Paradisiaca sp.) MENGGUNAKAN METODE DPPH (1,1-difenil-2-pikrilhidrazil)","authors":"Ahwan Abdul, Roudlotul Jannah, Fadilah Qonitah","doi":"10.47701/djp.v2i2.2433","DOIUrl":"https://doi.org/10.47701/djp.v2i2.2433","url":null,"abstract":"Penyakit degeneratif dapat disebabkan oleh radikal bebas, namun dapat dilawan secara alami oleh tubuh dengan antioksidan. Natural antioxidant dapat diperoleh dari tumbuhan, buah-buahan dan biji-bijian seperti pada jantung buah pisang. Jantung buah pisang yang memiliki kandungan senyawa fenolik, berpotensi memiliki aktivitas antioksidan. Tujuan dari penelitian adalah untuk mengetahui aktivitas antioksidan jantung pisang nangka, ambon dan tanduk, serta untuk mengetahui perbedaan nilai aktivitas antioksidan. Penelitian dilakukan bersifat eksperimental dan diuji secara kuantitatif. Uji aktivitas antioksidan dengan metode DPPH (1,1-difenil-2-pikrilhidrazil) secara spektrofotometer UV-Vis pada panjang gelombang maksimum 517 nm dan Operating Time (OT) selama 30 menit. Penelitian ini menggunakan kontrol positif vitamin C dengan konsentrasi 5 ppm, 7,5 ppm, 10 ppm, 12,5 ppm dan 15 ppm. Sampel yang digunakan yaitu ekstrak etanol kental jantung pisang nangka, ambon, dan tanduk dengan konsentrasi 50 ppm, 100 ppm, 200 ppm, 300 ppm dan 400 ppm. Hasil uji aktivitas antioksidan dinyatakan dengan nilai IC50, pada Vitamin C 8,25±0,05 µg/mL (antioksidan kuat), jantung pisang nangka 276,54±8,19 µg/mL (antioksidan lemah), ambon 136,04±2,30 µg/mL (antioksidan sedang),  dan tanduk 111,22±1,76 µg/mL (antioksidan sedang). Hasil uji aktivitas antioksidan dilanjutkan dengan analisis data menggunakan uji Kruskal-Wallis menunjukkan p-value < 0,05. Kesimpulan penelitian ini adalah ada perbedaan aktivitas antioksidan pada ekstrak etanol jantung pisang nangka, ambon, dan tanduk.","PeriodicalId":182338,"journal":{"name":"Duta Pharma Journal","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132353871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PENENTUAN KADAR ALKALOID TOTAL DAN FENOLIK TOTAL DALAM EKSTRAK ETANOL UMBI RUMPUT TEKI (Cyperus Rotundus L.)","authors":"Y. Kristariyanto, Novena Adi Yuhara, E. Rawar","doi":"10.47701/djp.v2i1.1862","DOIUrl":"https://doi.org/10.47701/djp.v2i1.1862","url":null,"abstract":"Rumput teki (Cyperus Rotundus L.) adalah rumput liar yang telah digunakan sebagai obat tradisional. Flavonoid yang terkandung dalam umbi rumput teki pernah ditetapkan kadarnya, namun alkaloid total dan fenolik total belum pernah dilakukan Penelitian ini bertujuan untuk menetapkan kadar alkaloid total dan fenolik total dalam ekstrak etanol umbi rumput teki (Cyperus Rotundus L.). Ekstrak etanol umbi rumput teki dibuat dengan cara mengeringkan umbi, menyerbukkan umbi yang kering, dan merendam serbuk selama 24 jam dengan etanol 96%, kemudian diuapkan dengan rotary evaporator hingga terbentuk ekstrak kental. Penetapan kadar alkaloid total dan fenolik total dalam ekstrak kental tersebut dilakukan dengan metode spektofotometri UV-Vis. Hasil penelitian menunjukkan bahwa kandungan alkaloid total dan fenolik total dalam ekstrak etanol umbi rumput teki adalah 3,40% dan 1,03%.","PeriodicalId":182338,"journal":{"name":"Duta Pharma Journal","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121933452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pengaruh Waktu Ekstraksi Pada Kadar Kafein Produk Biji Kopi Arabica Dari Kabupaten Tegal Dengan Metode Spektrofotometri Uv-Vis","authors":"Yuzar Khasan Yusuf, Desy Ayu Irma Permatasari, Weri Veranita","doi":"10.47701/djp.v2i1.1704","DOIUrl":"https://doi.org/10.47701/djp.v2i1.1704","url":null,"abstract":"Indonesia merupakan salah satu negara produsen kopi dunia, saat ini Indonesia berada pada urutan keempat negara pengekspor kopi dunia. Data BPS tahun 2018, Kabupaten Tegal memiliki lahan perkebunan kopi seluas 122,93 Ha. Sampel pada penelitian ini adalah produk kopi Arabica Wine, Fulwash, Honey dan Natural dengan perbandingan waktu ektraksi 0 jam, 1 jam dan 3 jam. Metode penerapan kadar kafein pada penelitian ini menggunakan spektrofotometri UV-Vis. Hasil penentuan kadar kafein dengan perbandingan waktu ekstraksi 0 jam (T 0), waktu ekstraksi 1 jam(T 1) dan waktu ekstraksi 3 jam (T 3) yaitu : Sampel Kopi Arabica Wine T 0 = 5.0 %, T 1 = 5.8 % dan T 3 = 8.8%. Sampel Kopi Arabica Fullwash T 0 = 5.4%, T 1 = 6.0% dan T 3 = 8.3%. Sampel Kopi Arabica Honey T 0 = 5.3%, T 1 = 6.5% dan T 3 = 7.9% dan Sampel Kopi Arabica Natural T 0 = 5.7%, T 1 = 6.8% dan T 3 = 7.9%. Analisa data hasil penelitian secara statistik dilakukan dengan metode one-way ANOVA dan dilanjutkan dengan uji pos hoc Tukey HSD dengan hasil signifikansi 0.001, maka dapat disimpulkan bahwa hasil penelitian terdapat perbedaan makna yang signifikan antara kadar kafein dengan waktu ekstraksi T 0, T 1 dan T 3.\u0000Kata kunci : ","PeriodicalId":182338,"journal":{"name":"Duta Pharma Journal","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130145950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analisis Profil Fisika Kimia dan Farmakokinetik Senyawa Pentagamavunon-1 Secara Komputasi","authors":"Eva Kholifah, E. Endah","doi":"10.47701/djp.v2i1.1679","DOIUrl":"https://doi.org/10.47701/djp.v2i1.1679","url":null,"abstract":"Pentagamavunon-1 (PGV-1) is a curcumin analog which is known to inhibit the growth of cancer cells, bacteria and inhibit free radicals as an antioxidant agent. The purpose of this study was analyzed the pharmacokinetic profile and physicochemical properties of PGV-1 computationally. The predicted parameters were Lipinski rule of five, bioavailability, Blood Brain Barrier (BBB) ​​absorption, GI absorption, P-gp substrate, and prediction of metabolic enzymes involved in drug ADME processes. The results of this study indicate that the compound PGV-1 complies with the Lipinski rule of five with the characteristics of a molecular weight of 348.43 g/mol, hydrogen donor 2, hydrogen acceptor 3, Log P 4.71 and molar refractory 40-130. PGV-1 could absorb through the GI and can pass the blood brain barrier passively without P-gp protein. Several enzymes involved in the metabolism of PGV-1 are CYP2C19, CYP2C9, CYP 3A4. Thus, our finding suggest that PGV-1 can be developed as a drug target compound for active oral drugs.","PeriodicalId":182338,"journal":{"name":"Duta Pharma Journal","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124123303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship Between Length of Rehabilitation and Quality of Life for Psychoactive Substance Users in Yogyakarta","authors":"Ani Kristiyani, Envan Widya Chrisnawan, Aloysia Yossy Kurniawaty, Sarah Puspita Admaja, Y. Kristariyanto","doi":"10.47701/djp.v2i1.1711","DOIUrl":"https://doi.org/10.47701/djp.v2i1.1711","url":null,"abstract":"The background of this research is the use of psychoactive substances causes complex problems and becomes a threat to the state. Rehabilitation can reduce the risk of relapse of psychoactive substance abuse and the risk of crime, thereby improving quality of life. Understanding rehabilitation with quality of life has a positive impact on users of psychoactive substances. Therefore, it is essential to study the relationship between the length of rehabilitation and the quality of life of users of psychoactive substances. The purpose of this study was to determine the relationship between the size of rehabilitation and the quality of life for users of psychoactive substances. This research method is a non-experimental observational analytic study with a cross-sectional design. The subjects of the study were users of psychoactive substances who were undergoing the rehabilitation process at the Class IIA Narcotics Prison in Yogyakarta. Quality of life was measured by the World Health Organization Quality of Life BREF (WHOQOL-BREF) instrument. The significance level of the statistical test was stated at p<0.05. Data analysis used the Spearman Rank correlation test and multiple linear regression. The results of this study carried out for two months (March to April 2021) obtained a total of 77 subjects using psychoactive substances. The length of rehabilitation has a significant positive correlation with the quality of life, indicated by the value of p = 0.048 (p <0.05) and r = 0.220, which means that the longer the respondent undergoes rehabilitation, the better the quality of his life. This study concludes that there is a significant relationship between the length of repair and quality of life for users of psychoactive substances. \u0000 ","PeriodicalId":182338,"journal":{"name":"Duta Pharma Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132023844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PENGARUH KOMBINASI GELLING AGENT CARBOPOL 934 DAN NATRIUM CARBOXYMETHYLCELLULOSE (Na-CMC) TERHADAP STABILITAS FISIK GEL GETAH JARAK PAGAR (Jatropha curcas) SEBAGAI PENYEMBUH LUKA INSISI","authors":"A. Santoso, Yetti Hariningsih, Novi Ayuwardani","doi":"10.47701/djp.v2i1.1282","DOIUrl":"https://doi.org/10.47701/djp.v2i1.1282","url":null,"abstract":"Background: Jatropha sap (Jatropha curcas) is one of the herbal plants that contain tannins and saponins which are responsible for wound healing. Purpose: This study aims to determine the effect of the combination of Carbopol 934 and Na-CMC as a gelling agent on the physical stability of Jatropha curcas (Jatropha curcas) latex as a wound healing agent. Method: The method used in this study was to compare the combination of carbopol 934 and Na-CMC with different concentrations in the three formulations. The concentration used is 1%:4%, 1.5%:3,5% and 2%:3%. The three formulations will be tested for physical quality and tested for physical stability for 4 weeks. Then the formulation will be tested for primary irritation and incision wound healing test. Result: The results of the study showed that formulation I with a concentration of 1%:4% had a good physical quality test based on the results of tests carried out according to standards. Based on the results of the physical stability test, it showed stable adhesion results, while the pH, dispersibility and viscosity tests showed a change in storage for 4 weeks. Jatropha (Jatropha curcas) latex gel formulation did not cause primary irritation to rabbits. The three formulations have the ability to heal fast wounds on the 9th day. \u0000  \u0000 ","PeriodicalId":182338,"journal":{"name":"Duta Pharma Journal","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116206943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anthelmintic Test of Combination of Carrot Peels (Daucus carota L.) and Pineapple Peels (Ananas comusus) Juice Against Silkworms (Tubifex sp)","authors":"Yossy Febryarti, Yetti Hariningsih, Oktaviarika Dewi Hermawatiningsih","doi":"10.47701/djp.v2i1.1283","DOIUrl":"https://doi.org/10.47701/djp.v2i1.1283","url":null,"abstract":"Background: Anthelmintics is a treatment used as an anti-worm that can eradicate worms in the human and animal bodies, one of which is against silk worms (Tubifex sp). One of the plants that may be used as anthelmintics is carrot skin (Daucus carota L.) and pineapple skin (Ananas comusus). Carrot peel contains flavonoids, quercetin, and tannins as anthelmintics and pineapple peel contains flavonoids, bromealin enzymes and tannins, so researchers are interested in making a combination of carrot peel juice and pineapple peel juice as an anthelmintic against silk worms (Tubifex sp). Objective: This study aims to determine the effectiveness of the combination of carrot peel and pineapple peel juice in eradicating silk worms (Tubifex sp). Methods: The method used is the squeeze method, specific specific standardization, lethal time test, paralysis time test. , the anthelmintic activity test of the combination of carrot peel juice and pineapple peel extract with concentrations of F1 25%: 75%, F2 50%: 50%, F3 75%: 25% using positive control Albendazole 0.06% w/v. The research data were analyzed using the Oneway Anova test. Results: The results of this study showed that the combination of carrot peel extract 75%: pineapple peel 25% had the best anthelmintic effectiveness against the lethal time. The anthelmintic effectiveness test obtained from the combination of carrot juice 25%: pineapple juice 75% showed the best results during paralysis time. The lethal time test of the combination of carrot peel and pineapple juice obtained an average time of death in F1 of 15.32 minutes. In F2, the average time of death was 18.155 minutes, while in F3 it was 20.37 minutes and the Oneway Anova result was p=0.000 (p<0.05). The paralysis time test for the combination of carrot peel and pineapple juice was found to have an average paralysis time of 13.625 minutes in F1. In F2, the average paralysis time was 13,733 minutes, while in F3 18,712 minutes and the Oneway Anova result was p=0,000 (p<0,05). Conclusion: The best combination of juice for the time of death is F1 with a concentration of 25% carrot juice: 75% pineapple juice, while the best combination for paralysis time is F1 with a 25% carrot juice concentration: 75% pineapple juice.                                                                         \u0000Keywords : Carrot Peels (Daucus carota L.), Pineapple Peels (Ananas comosus), Anthelmintics, Tubifex sp","PeriodicalId":182338,"journal":{"name":"Duta Pharma Journal","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121193939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}