{"title":"Evolution of the Serotypes of aggregatibacter Actinomycetemcomitans In Relation to Aggressive Periodontitis and Geographic Origin of Individuals – A Review of the Literature","authors":"Chi‐Cheng Tsai, Ying-Chu Lin","doi":"10.31031/MRD.2019.03.000572","DOIUrl":"https://doi.org/10.31031/MRD.2019.03.000572","url":null,"abstract":"Aggressive periodontitis is a severe and rapidly progressing form of periodontitis [1,2] that affecting supporting tissues of the teeth induced by microbial deposits [3]. Aggregatibacter actinimycetemcomitans is an important pathogen related to aggressively progressive periodontal breakdown in adolescents and adults [4,5]. A. actinomycetemcomitans (A.a.) can be grouped into seven serotypes (a-g) [6,7]. Several studies have examined the relationship of A.a. serotype, ethnical status and geographic populations, periodontal disease status [8,9,10]. Individuals are usually colonized by a single serotype that can exist for life [8,11,12]. The frequency distribution of A.a. serotypes differs among various populations [13]. The available literature suggests that serotypes a, b. and c occur much more often among oral isolates than d, e, f and g [14,15,16]. The serotype distributions have been shown to be different among various geographic populations including African, Asian, Europeans, and North and South American [15,16,17,18,19]. The purpose of the present study was to review the studies that have investigated the prevalence and the distribution of A.a. serotypes in subgingival samples Crimson Publishers Wings to the Research Review Article","PeriodicalId":179841,"journal":{"name":"Modern Research in Dentistry","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127977084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Urine Cortisol and Psychological Factors in a Sample of Patients with Dental Anxiety","authors":"Chávez Mmc","doi":"10.31031/MRD.2019.03.000571","DOIUrl":"https://doi.org/10.31031/MRD.2019.03.000571","url":null,"abstract":"","PeriodicalId":179841,"journal":{"name":"Modern Research in Dentistry","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122712570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vital Pulp Therapy Challenges and Promises in Permanent Teeth","authors":"Fahda N. Algahtani","doi":"10.31031/MRD.2019.03.000569","DOIUrl":"https://doi.org/10.31031/MRD.2019.03.000569","url":null,"abstract":"The question about the exact indications and contraindications of vital pulp therapy in permanent teeth never settled down. Because the answer involves multiple factors such as understanding the complex nature of the carious disease, knowing the pathological state inside the pulp, and recognizing the capabilities and the limits of the biomaterials in stimulating repair. This review examines some of the challenges and promises of vital pulp therapy for permanent teeth.","PeriodicalId":179841,"journal":{"name":"Modern Research in Dentistry","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125512724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Studying the Efficiency of Endoscopic Method in Facial Fractures Treatment","authors":"Fathi Hr, Davudov Mm, Mammadov Jj","doi":"10.31031/MRD.2019.03.000567","DOIUrl":"https://doi.org/10.31031/MRD.2019.03.000567","url":null,"abstract":"Maxillofacial injuries are considered as one of the most important health difficulties in all over the world. Especially because it tends to appear highly and with various wastages [1-3]. In addition to these Maxillofacial fractures it accompanies with Severe morbidity, losing the function, deformity and significant cost [3-5]. Maxillofacial fractures mainly affect men [6-11] and have the highest incidence in the age range of 20-30 [7-9]. The maxillofacial fractures reasons are different among different population [9] and the most common causes in all over the world are traffic accidents, rape, falls, sport injuries and war [12-14]. Facial fracture treatments have been developed over the last century. Internal fixation with screws and plate (rigid internal fixation) has given us some tools for restoring the facial fractures with reduced morbidity more accurate [15]. In the last decade, alternative endoscopic approaches have been applied for restoring the facial fractures for achieving equal results to traditional approaches but with reduced morbidity (Figure1 & 2). So, that endoscopy which access-minimal technique has limited using the cutting for creating exposer [16,17]. Figure 1: Frontal fracture endoscopic treatment.","PeriodicalId":179841,"journal":{"name":"Modern Research in Dentistry","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129093560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Possibilities of the Use of Stem Cells in Parodoncium Regeneration","authors":"Mladen Vukovic","doi":"10.31031/MRD.2019.03.000568","DOIUrl":"https://doi.org/10.31031/MRD.2019.03.000568","url":null,"abstract":"Parodontopathy is a chronic inflammatory disease of periodontium which can result in irreversible damage to the tissue, resulting in loss of contact between the tooth and its supporting device. Periodontal disease is the response of the immune system to the accumulation of plaque and oral microorganisms, which leads to a progressive loss of gingival tissue, periodontal ligament and alveolar bone. If it is not treated it can lead to premature loss of teeth. Parodontopathy is also associated with many systemic disorders such as diabetes, rheumatoid arthritis and cardiovascular complications, and its development is associated with a negative outcome of pregnancy. Due to all of this, periodontal disease significantly affects the patient’s quality of life and has a significant financial impact on both the patient and the public health system. The ultimate goal of periodontal therapy is to achieve periodontal regeneration with the reconstruction of all parodontium components including periodontal ligament, connective gingival tissue, cement and alveolar bone. The treatments currently in use in the world and in our country can’t completely reconstruct all of this tissues and relationships damaged by periodontal disease [1].","PeriodicalId":179841,"journal":{"name":"Modern Research in Dentistry","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127137645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luísa Gallo Da, Antonia Zancanaro Fm, C. Karen, Gonçalves Sf
{"title":"Radiotherapy-Induced Salivary Hypofunction: An Update on the Preventive Mechanisms","authors":"Luísa Gallo Da, Antonia Zancanaro Fm, C. Karen, Gonçalves Sf","doi":"10.31031/MRD.2019.03.000566","DOIUrl":"https://doi.org/10.31031/MRD.2019.03.000566","url":null,"abstract":"The saliva is a fluid of extreme importance in the maintenance of oral homeostasis, being present in several biologic processes. It is composed in almost its totality by water and electrolytes, besides proteins such as immunoglobulins and mucins. This fluid acts in the lubrication of the mucosa, digestion, phonation, gustation, neutralization of acid components and in the immune systems through antimicrobial peptides against bacteria, fungi and viroses [1-5]. Hyposalivation is characterized by the decrease in the capacity of the salivary glands to secrete saliva, and xerostomia is defined as the subjective sensation of oral dryness. Such alterations can be caused by drugs, systemic diseases, head and neck radiotherapy, among other reasons [6]. Patients affected by salivary dysfunctions tend to show an atrophic oral mucosa, as well as symptoms such as dysphonia, dysphagia, oral burning sensation and palate alterations. There is increased risk to oral candidiasis, caries lesions and periodontal alterations [7-9]. The diminished bactericidal effect of saliva favors the increase of population of the microorganisms responsible for these diseases [8,10]. Head and neck radiotherapy is one of the main causes of salivary dysfunction [11,12]. The major salivary glands are usually included in the radiation portals due to the fact that they reside close to primary tumor sites and lymphatic chains of the head and neck region and frequently have their function impaired resulting in hyposalivation and xerostomia [11,13-15]. Among the radiotherapy methods most employed in head and neck region, conventional 2D radiotherapy (RC) is the one that presents the most significant side effects on the glandular tissue. Intensity-modulated radiotherapy (IMRT) and three dimensional conformal radiotherapy (3DCRT) reduce the radiation dose on the health structures close to the tumor and, consequently, the toxicity caused by the ionizing radiation [13,1620]. The salivary glands are extremely sensitive to ionizing radiation, presenting structural alterations which cause changes in salivary flow and composition [21]. These alterations are dose-dependent and can be irreversible [21,22]. Permanent hyposalivation is frequently associated to doses of ≥50 Gy, usually used for head and neck cancer treatment [23].","PeriodicalId":179841,"journal":{"name":"Modern Research in Dentistry","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117083702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"“Giving Back, and Looking Forward”","authors":"Ratnakar R. Ghorpade","doi":"10.31031/mrd.2019.03.000565","DOIUrl":"https://doi.org/10.31031/mrd.2019.03.000565","url":null,"abstract":"","PeriodicalId":179841,"journal":{"name":"Modern Research in Dentistry","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125334263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Internal Root Resorption: Should we Change our Vision?","authors":"Juan Gaston Robledo","doi":"10.31031/mrd.2018.03.000564","DOIUrl":"https://doi.org/10.31031/mrd.2018.03.000564","url":null,"abstract":"Internal Root Resorption is usually asymptomatic. Manifest itself under pathologic conditions and requires vital pulp tissue for their development. Etiologic factors such as trauma, inflammation, caries, restorative procedures have been suggested. If the lesion is detected early and of small size, the prognosis is favorable. Studies revealed that resorptive process in teeth is comparable to bone resorption. Cleaning and shaping with hand-files/rotary instruments, irrigants, ultrasonic instrumentation and calcium hydroxide are considered essential for arresting the resorptive activity. However, exists a big challenge due to the heterogeneity of pulpal space and creation of a conductive habitat to the healing of supporting tissues. Abbreviations: Internal root resorption; Endodontics; Osteoclast/odontoclast activity Modern Research in Dentistry C CRIMSON PUBLISHERS Wings to the Research","PeriodicalId":179841,"journal":{"name":"Modern Research in Dentistry","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126939213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hypothesis of Cancer Stem Cells and Stem Cells of Head and Neck Cancer–Biomarkers for their Identification","authors":"Mladen Vukovic","doi":"10.31031/MRD.2018.03.000563","DOIUrl":"https://doi.org/10.31031/MRD.2018.03.000563","url":null,"abstract":"Stem cells are characterized by their self-renewal capacity and the ability to differentiate into any type of mature cell. In addition to normal stem cells, cancerous stem cells have been found to be responsible for the growth and spread of tumors. According to the CSC hypothesis CSC leads to tumorigenesis and tumor growth. Head and neck cancer are the sixth most common cancer and about 300,000 new cases are diagnosed every year. Despite progress in treatment, the 5-year survival rate for this cancer has not improved over the past 30 years. In the hierarchical structure of stem cells present in the human oral epithelium, it is clear that stem cells are the only long-lived inhabitants of the oral epithelium and, therefore, the only cells capable of accumulating the required number of genetic changes for the development of malignancy. The major surface phenotypic markers associated with SC and CSC characteristics include CD133, CD44 and CD24. Abbreviations: CSC: Cancer Stem Cells; SC: Stem Cells; HNSCC: Head and Neck Squamous Carcinoma Cells; ATC: Amplifying Transitory Cells; NOD/ SCID: Non-obese diabetic/Severe Combined Immunodeficiency; OSCC: Oral Squamous Cell Carcinoma; DNA: Deoxyribonucleic Acid; EMT: Epithelial Mesenchymal Transition; SP: Sidepopulation; HPV: Human Papillomavirus; HNC: Head and Neck Cancer; UADT: Upper Aerodigestion Cancer Modern Research in Dentistry C CRIMSON PUBLISHERS Wings to the Research","PeriodicalId":179841,"journal":{"name":"Modern Research in Dentistry","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123529050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Marvel of 3D Imaging: A Case of an Undetectable Condylar Split Fracture","authors":"G. Pauly, N. Ashok","doi":"10.31031/mrd.2018.03.000561","DOIUrl":"https://doi.org/10.31031/mrd.2018.03.000561","url":null,"abstract":"Radiography has become one of the cornerstones for palatable diagnosis in the world of medical sciences. Even amongst our dental fraternity; the use of conventional radiographs in day-to-day cases has increased considerably over the past few decades. With the arrival of 3D imaging, the credibility of oral diagnosis has leapfrogged to a different level. The purpose of this article is to present a case of an undetectable split fracture of the condyle, only made perceptible, courtesy 3D imaging.","PeriodicalId":179841,"journal":{"name":"Modern Research in Dentistry","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122008684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}