Clinical Possibilities of the Use of Stem Cells in Parodoncium Regeneration

Parodontopathy is a chronic inflammatory disease of periodontium which can result in irreversible damage to the tissue, resulting in loss of contact between the tooth and its supporting device. Periodontal disease is the response of the immune system to the accumulation of plaque and oral microorganisms, which leads to a progressive loss of gingival tissue, periodontal ligament and alveolar bone. If it is not treated it can lead to premature loss of teeth. Parodontopathy is also associated with many systemic disorders such as diabetes, rheumatoid arthritis and cardiovascular complications, and its development is associated with a negative outcome of pregnancy. Due to all of this, periodontal disease significantly affects the patient’s quality of life and has a significant financial impact on both the patient and the public health system. The ultimate goal of periodontal therapy is to achieve periodontal regeneration with the reconstruction of all parodontium components including periodontal ligament, connective gingival tissue, cement and alveolar bone. The treatments currently in use in the world and in our country can’t completely reconstruct all of this tissues and relationships damaged by periodontal disease [1].