Evolution of the Serotypes of aggregatibacter Actinomycetemcomitans In Relation to Aggressive Periodontitis and Geographic Origin of Individuals – A Review of the Literature

Aggressive periodontitis is a severe and rapidly progressing form of periodontitis [1,2] that affecting supporting tissues of the teeth induced by microbial deposits [3]. Aggregatibacter actinimycetemcomitans is an important pathogen related to aggressively progressive periodontal breakdown in adolescents and adults [4,5]. A. actinomycetemcomitans (A.a.) can be grouped into seven serotypes (a-g) [6,7]. Several studies have examined the relationship of A.a. serotype, ethnical status and geographic populations, periodontal disease status [8,9,10]. Individuals are usually colonized by a single serotype that can exist for life [8,11,12]. The frequency distribution of A.a. serotypes differs among various populations [13]. The available literature suggests that serotypes a, b. and c occur much more often among oral isolates than d, e, f and g [14,15,16]. The serotype distributions have been shown to be different among various geographic populations including African, Asian, Europeans, and North and South American [15,16,17,18,19]. The purpose of the present study was to review the studies that have investigated the prevalence and the distribution of A.a. serotypes in subgingival samples Crimson Publishers Wings to the Research Review Article