发布求助
文献互助 智能选刊 最新文献

Kanzo最新文献

筛选
英文 中文
肝疾患診療連携拠点病院における肝炎医療コーディネーターの現状（第2報） 肝病诊疗协作据点医院的肝炎医疗协调者的现状(第2报)
Kanzo Pub Date : 2023-10-01 DOI: 10.2957/kanzo.64.510
Hiroshi Isoda, Masaru Enomoto, Hirokazu Takahashi, Takashi Oono, Taisuke Inoue, Tadashi Ikegami, Tatsuya Ide, Yoshio Tokumoto, Koji Ogawa, Hiroko Setoyama, Yoshihito Uchida, Masami Hashimoto, Kenichi Hirota, Satoru Kakizaki, Sachiko Tatsuki, Takako Inoue, Mizuki Endo, Tetsuro Shimakami, Yoshihisa Arao, Jun Inoue, Atsushi Suetsugu, Kenji Nagata, Masaaki Korenaga
{"title":"肝疾患診療連携拠点病院における肝炎医療コーディネーターの現状（第2報）","authors":"Hiroshi Isoda, Masaru Enomoto, Hirokazu Takahashi, Takashi Oono, Taisuke Inoue, Tadashi Ikegami, Tatsuya Ide, Yoshio Tokumoto, Koji Ogawa, Hiroko Setoyama, Yoshihito Uchida, Masami Hashimoto, Kenichi Hirota, Satoru Kakizaki, Sachiko Tatsuki, Takako Inoue, Mizuki Endo, Tetsuro Shimakami, Yoshihisa Arao, Jun Inoue, Atsushi Suetsugu, Kenji Nagata, Masaaki Korenaga","doi":"10.2957/kanzo.64.510","DOIUrl":"https://doi.org/10.2957/kanzo.64.510","url":null,"abstract":"Hepatitis medical care coordinators (HMCCs) in Japan are trained by local governments and regional core centers, and are expected to play an active role in various aspects of hepatitis countermeasures. A 2019 survey revealed varied activity statuses of HMCCs among facilities. This study surveyed the present status of HMCCs in 21 of the 72 regional core centers in the fiscal year 2021.","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"188 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135663610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of activities to pick up hepatitis virus-positive patients through multidisciplinary cooperation 多学科合作捡拾肝炎病毒阳性患者活动的成效
Kanzo Pub Date : 2023-10-01 DOI: 10.2957/kanzo.64.487
Yoshiko Fujiwara, Hideto Kawaratani, Chizuko Fujii, Kazumi Wada, Seka Okada, Takuya Kubo, Takemi Akahane, Kouji Yanase, Yoshiyuki Nakagawa
{"title":"Effectiveness of activities to pick up hepatitis virus-positive patients through multidisciplinary cooperation","authors":"Yoshiko Fujiwara, Hideto Kawaratani, Chizuko Fujii, Kazumi Wada, Seka Okada, Takuya Kubo, Takemi Akahane, Kouji Yanase, Yoshiyuki Nakagawa","doi":"10.2957/kanzo.64.487","DOIUrl":"https://doi.org/10.2957/kanzo.64.487","url":null,"abstract":"2019年から肝炎医療コーディネーター（肝Co）活動による肝炎ウイルス陽性者の拾い上げを開始した．2019年から2021年までは肝炎ウイルス（HBV，HCV）陽性者に対して検査依頼医へ電子カルテのアラート機能を用いたメッセージ記載による専門医への受診勧奨が主な取り組みであった．しかし，検査結果を伝えられていないHCV陽性者は2019年の52.5％（32/61）から2021年は26.7%（12/45）と減少したものの，0％とならず新たな対策が必要と考えた．2022年に多職種で構成された「肝炎対策チーム」を立ち上げ，肝炎ウイルス陽性者確認後の流れを明確にした「フローチャート」を作成し拾い上げ活動を強化した．その結果，HCV陽性者に検査結果が伝わっていない症例は，2022年には5.3%（3/57）と著減した．「フローチャート」を軸とした肝Co活動は，多職種連携により効果的に機能したと考える．","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135662925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
進行肝細胞癌に対するアテゾリズマブ＋ベバシズマブ併用療法開始直後に発症した腫瘍の胆囊穿破による胆道出血の1例 阿替唑单抗+贝伐西单抗联合治疗晚期肝细胞癌刚开始不久，肿瘤的胆囊穿破导致胆道出血1例
Kanzo Pub Date : 2023-10-01 DOI: 10.2957/kanzo.64.497
Yukako Shoji, Takeshi Senju, Yusuke Morita, Yuki Tanaka, Rie Sugimoto
{"title":"進行肝細胞癌に対するアテゾリズマブ＋ベバシズマブ併用療法開始直後に発症した腫瘍の胆囊穿破による胆道出血の1例","authors":"Yukako Shoji, Takeshi Senju, Yusuke Morita, Yuki Tanaka, Rie Sugimoto","doi":"10.2957/kanzo.64.497","DOIUrl":"https://doi.org/10.2957/kanzo.64.497","url":null,"abstract":"進行肝細胞癌に対するアテゾリズマブ（Atezo）＋ベバシズマブ（Bev）併用療法開始直後に発症した腫瘍の胆囊穿破による胆道出血の1例を報告する．症例は70代男性．進行肝細胞癌に対して，day1に一次薬物療法としてAtezo＋Bev併用療法を導入したところ，day2に心窩部痛が出現した．Day3に腫瘍の胆囊穿破による胆道出血から胆管閉塞を来したと判断し，緊急ERCP（内視鏡的逆行性胆管膵管造影検査）で胆道ドレナージを行った．腫瘍からの出血に対しては，day6に腫瘍血管A6に対してTAE（肝動脈塞栓療法）を施行した．Bevが胆道出血に関与したと考えられ，Atezo＋Bev併用療法は中止し，レンバチニブ（Len）を導入し，その後のCTでは腫瘍の縮小を認めた．","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"266 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135663430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Situation of hepatitis virus tests and measures to link test-positive individuals to specialists: a survey of institutions in Chiba, Japan, specializing in liver diseases 肝炎病毒检测的情况和将检测阳性个体与专家联系起来的措施:对日本千叶专门研究肝病的机构的调查
Kanzo Pub Date : 2023-10-01 DOI: 10.2957/kanzo.64.517
Masato Nakamura, Soichiro Kiyono, Kentaro Fujimoto, Tadayoshi Kogure, Sae Yumita, Keita Ogawa, Terunao Iwanaga, Miyuki Nakagawa, Kisako Fujiwara, Hiroaki Kanzaki, Keisuke Koroki, Masanori Inoue, Kazufumi Kobayashi, Naoya Kanogawa, Takayuki Kondo, Sadahisa Ogasawara, Ryo Nakagawa, Shingo Nakamoto, Ryosuke Muroyama, Jun Kato, Naoya Kato
{"title":"Situation of hepatitis virus tests and measures to link test-positive individuals to specialists: a survey of institutions in Chiba, Japan, specializing in liver diseases","authors":"Masato Nakamura, Soichiro Kiyono, Kentaro Fujimoto, Tadayoshi Kogure, Sae Yumita, Keita Ogawa, Terunao Iwanaga, Miyuki Nakagawa, Kisako Fujiwara, Hiroaki Kanzaki, Keisuke Koroki, Masanori Inoue, Kazufumi Kobayashi, Naoya Kanogawa, Takayuki Kondo, Sadahisa Ogasawara, Ryo Nakagawa, Shingo Nakamoto, Ryosuke Muroyama, Jun Kato, Naoya Kato","doi":"10.2957/kanzo.64.517","DOIUrl":"https://doi.org/10.2957/kanzo.64.517","url":null,"abstract":"A questionnaire survey of medical institutions Chiba Prefecture, Japan, specializing in liver diseases was conducted. This study aimed to provide an overview of the current hepatitis virus tests situations and measures taken to link test-positive individuals to specialists. The positivity rate in these institutions was high, with 2.2% for hepatitis C antibody (HCVAb) and 0.9% for hepatitis B surface antigen (HBsAg). Although many institutions (70%) had been employing linking measures, the consultation rate with hepatologists was low, with 7.6% and 14.3% for HCVAb- and for HBsAg-positive cases, respectively. Only half of the institutions disclosed that their measures were working well. These data suggested the importance of improving the system for determining test-positive individuals and promoting hepatologist consultation.","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"205 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135663605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
原因が不明であった肝palisading granulomaの1例 原因不明的肝palisading granuloma的一个例子
Kanzo Pub Date : 2023-10-01 DOI: 10.2957/kanzo.64.504
Chiharu Nakasu, Shinichiro Yamada, Hiroki Teraoku, Yu Saito, Tetsuya Ikemoto, Yuji Morine, Mitsuo Shimada
{"title":"原因が不明であった肝palisading granulomaの1例","authors":"Chiharu Nakasu, Shinichiro Yamada, Hiroki Teraoku, Yu Saito, Tetsuya Ikemoto, Yuji Morine, Mitsuo Shimada","doi":"10.2957/kanzo.64.504","DOIUrl":"https://doi.org/10.2957/kanzo.64.504","url":null,"abstract":"患者は50代女性．検診の腹部超音波検査で肝S3に16×14 mm大の腫瘤を指摘され精査加療目的に当科紹介となった．既往歴・生肉食歴なし．術前の血液検査で異常なく，末梢好酸球も正常．造影CTの動脈・門脈相では辺縁に造影効果を認めるが，平衡相では造影されず，MRI T1強調像で低信号，T2強調像で低～等信号，拡散強調像でやや高信号であった．PET-CTで肝臓への集積は認めなった．悪性腫瘍の可能性を完全に否定できず，腹腔鏡下肝部分切除を施行した．病理組織学的には腫瘤全体に凝固壊死像が見られ，辺縁に線維増生を伴い，組織球が柵状に配列したpalisading granulomaであった．原因特定のために複数の染色を行ったが，病原体は同定できなかった．palisading granulomaは術前診断が困難であり，診断的治療として腹腔鏡下肝切除術は有用であると考えられた．","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135663634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Results of a questionnaire survey on career support, role of academic societies, and social networking -Questionnaire at the 44th meeting of the eastern branch of Japan Society of Hepatology- 职业支持、学术团体的作用和社会网络的问卷调查结果-日本肝病学会东部分会第44次会议问卷
Kanzo Pub Date : 2023-10-01 DOI: 10.2957/kanzo.64.476
Miyako Murakawa, Kyoko Hoshikawa, Mina Nakagawa, Satoshi Tanaka, Sachiyo Yoshio, Goki Suda, Kazumichi Abe, Hidekatsu Kuroda, Hiroko Iijima
{"title":"Results of a questionnaire survey on career support, role of academic societies, and social networking -Questionnaire at the 44th meeting of the eastern branch of Japan Society of Hepatology-","authors":"Miyako Murakawa, Kyoko Hoshikawa, Mina Nakagawa, Satoshi Tanaka, Sachiyo Yoshio, Goki Suda, Kazumichi Abe, Hidekatsu Kuroda, Hiroko Iijima","doi":"10.2957/kanzo.64.476","DOIUrl":"https://doi.org/10.2957/kanzo.64.476","url":null,"abstract":"第44回日本肝臓学会東部会のキャリア支援・ダイバーシティ推進委員会関連企画の一環として，学会参加者を対象にキャリア支援・学会・SNSに関するアンケート調査を実施し，238名（男性78%，女性22%，40歳未満21%）から回答を得た．「希望するキャリアを継続する際の大きな障害」について最多回答は「時間的な余裕」（61%），次いで「支援体制の不備」（43%）であり，「キャリア支援・ダイバーシティ推進において重要だと思うこと」は「働く環境の整備」（58％）が最多だった．また，学位の取得や留学については肯定的な意見が多かった（学位81%，留学75%）．必要な学会の取り組みとしては，学術集会・教育講演会のハイブリッド開催（74%）や単位更新のweb化（51%）の要望が多かった．さらにSNSを利用している割合はFacebook 44%，Twitter 32％であり，Twitterは若い年代で多かった．","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"186 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135663436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
原発性胆汁性胆管炎：診療の進歩とアンメットニーズ 原发性胆汁性胆管炎:诊疗的进步和不确定需求
Kanzo Pub Date : 2023-10-01 DOI: 10.2957/kanzo.64.466
Atsumasa Komori
{"title":"原発性胆汁性胆管炎：診療の進歩とアンメットニーズ","authors":"Atsumasa Komori","doi":"10.2957/kanzo.64.466","DOIUrl":"https://doi.org/10.2957/kanzo.64.466","url":null,"abstract":"原発性胆汁性胆管炎（primary biliary cholangitis；PBC）は，慢性進行性自己免疫性肝疾患である．2000年代になりPBC診療の焦点は，ursodeoxycholic acid（UDCA）不応例に向かっている．Bezafibrateおよびobeticholic acidのadd-on投与が確立し，UDCA不応例の治療も進歩しているが，次世代add-on薬の開発，ならびにdual add-on療法の評価など，add-on不応例の一掃を目標とした試みが現在も展開されている．一方で，抗ミトコンドリア抗体陰性PBCおよびPBC-自己免疫性肝炎overlapの診断，治療反応と予後の予測，患者報告アウトカム（掻痒症）への対応と治療にも進歩がみられるが，課題も残っている．PBC診療の進歩とアンメットニーズ，次世代個別化医療への展望について概説する．","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"187 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135663620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
カボザンチニブ投与により著明に腫瘍縮小を認めたMET遺伝子増幅を伴う肝細胞癌の1例 一个MET基因扩增的肝细胞癌病例，通过服用cabanchinib明显缩小肿瘤
Kanzo Pub Date : 2023-10-01 DOI: 10.2957/kanzo.64.514
Satoru Hagiwara, Kazuomi Ueshima, Naoshi Nishida, Masatoshi Kudo
{"title":"カボザンチニブ投与により著明に腫瘍縮小を認めたMET遺伝子増幅を伴う肝細胞癌の1例","authors":"Satoru Hagiwara, Kazuomi Ueshima, Naoshi Nishida, Masatoshi Kudo","doi":"10.2957/kanzo.64.514","DOIUrl":"https://doi.org/10.2957/kanzo.64.514","url":null,"abstract":"We report a case of hepatocellular carcinoma with high mesenchymal-epithelial transition (MET) gene amplification demonstrating significant tumor shrinkage after cabozantinib treatment. A male patient in his fifties had far-advanced hepatocellular carcinoma and had previously been treated with combination therapy of lenvatinib or atezolizumab plus bevacizumab but had experienced progressive disease. We conducted FoundationOne® CDx, which is a comprehensive genomic profiling test, considering the next-line efficacious treatment options, and we confirmed high copy MET gene amplification. Hence, we administered cabozantinib, which caused a significant reduction in the tumor size. This case highlights the potential of comprehensive genomic profiling in identifying efficacious drugs and emphasizes the importance of actively conducting genomic testing to improve treatment outcomes.","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"131 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135663606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strategic International Session 国际战略会议
Kanzo Pub Date : 2023-09-20 DOI: 10.2957/kanzo.64.a533
{"title":"Strategic International Session","authors":"","doi":"10.2957/kanzo.64.a533","DOIUrl":"https://doi.org/10.2957/kanzo.64.a533","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139338221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
International Session (Symposium) 国际会议（专题讨论会）
Kanzo Pub Date : 2023-09-20 DOI: 10.2957/kanzo.64.a528
{"title":"International Session (Symposium)","authors":"","doi":"10.2957/kanzo.64.a528","DOIUrl":"https://doi.org/10.2957/kanzo.64.a528","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139338288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信