Kanzo最新文献

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Update on systemic therapy for hepatocellular carcinoma 肝细胞癌全身治疗的最新进展
Kanzo Pub Date : 2023-11-01 DOI: 10.2957/kanzo.64.540
Masafumi Ikeda, Taro Shibuki, Tomonao Taira, Kanae Inoue, Shota Yamaguchi, Ko Fukushi
{"title":"Update on systemic therapy for hepatocellular carcinoma","authors":"Masafumi Ikeda, Taro Shibuki, Tomonao Taira, Kanae Inoue, Shota Yamaguchi, Ko Fukushi","doi":"10.2957/kanzo.64.540","DOIUrl":"https://doi.org/10.2957/kanzo.64.540","url":null,"abstract":"肝細胞癌の薬物療法はソラフェニブ,レンバチニブなどの分子標的治療薬に代わり,アテゾリズマブ+ベバシズマブやデュルバルマブ+トレメリムマブといった免疫療法が主流となった.免疫療法が有効でない場合や免疫療法の適応がない場合に分子標的治療が選択される.年齢,Performance status,肝予備能,治療効果,有害事象などを考慮の上,治療法の選択が必要である.現在,Early stageでは根治治療の周術期治療,Intermediate stageでは肝動脈化学塞栓療法との併用療法,Advanced stageの一次治療,二次治療では新たな薬剤や併用療法などの開発が行われており,どのStageでも薬物療法が行われるようになった.これまで局所療法が主体だった肝細胞癌の治療も,薬物療法の併用療法が積極的に試みられるようになり,新たな治療開発は,薬物療法が中心となって行われている.","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"120 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135565165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fontan術後に発症した切除不能肝細胞癌の1例 Fontan术后出现的无法切除肝细胞癌的1例
Kanzo Pub Date : 2023-11-01 DOI: 10.2957/kanzo.64.567
Satoru Hagiwara, Kazuomi Ueshima, Naoshi Nishida, Hiroshi Ida, Kosuke Minaga, Yasunori Minami, Masahiro Takita, Tomoko Aoki, Masahiro Morita, Hirokazu Chishina, Takuya Matsubara, Naoya Omaru, Noboru Inamura, Masatoshi Kudo
{"title":"Fontan術後に発症した切除不能肝細胞癌の1例","authors":"Satoru Hagiwara, Kazuomi Ueshima, Naoshi Nishida, Hiroshi Ida, Kosuke Minaga, Yasunori Minami, Masahiro Takita, Tomoko Aoki, Masahiro Morita, Hirokazu Chishina, Takuya Matsubara, Naoya Omaru, Noboru Inamura, Masatoshi Kudo","doi":"10.2957/kanzo.64.567","DOIUrl":"https://doi.org/10.2957/kanzo.64.567","url":null,"abstract":"症例は30代男性.幼少期に完全大血管転位III型に対してFontan手術が施行され,近医に定期的に通院していた.20XX年7月腹部USで多発肝腫瘤を指摘され当院紹介受診となった.造影CTにて最大13 cmの多発肝細胞癌と判明した(BCLC stage B).画像上は門脈圧亢進所見や明らかな肝形態異常を認めなかったが,肝生検でCongestive Hepatic Fibrosis Score 3であり,実際には線維化の進展を認めていた.肝内多発のため外科手術やRFAの適応外であった.また最大径の腫瘍は肝外に突出しており,腹腔内破裂の危険性もあることから,まずTACEを施行した.再発に応じて各種抗癌剤治療を行い,生存中である.画像上は肝線維化を示唆する所見はなかったが,Fontan術後の特殊な循環動態では,肝線維化が進展している可能性があり,本症例を通して肝癌サーベイランスの重要性を再考する.","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"125 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135565590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
シンポジウム 研讨会
Kanzo Pub Date : 2023-10-25 DOI: 10.2957/kanzo.64.a687
{"title":"シンポジウム","authors":"","doi":"10.2957/kanzo.64.a687","DOIUrl":"https://doi.org/10.2957/kanzo.64.a687","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139314054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ワークショップ 工作坊
Kanzo Pub Date : 2023-10-25 DOI: 10.2957/kanzo.64.a765
{"title":"ワークショップ","authors":"","doi":"10.2957/kanzo.64.a765","DOIUrl":"https://doi.org/10.2957/kanzo.64.a765","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139314176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
若手セッション 青年会议
Kanzo Pub Date : 2023-10-25 DOI: 10.2957/kanzo.64.a898
{"title":"若手セッション","authors":"","doi":"10.2957/kanzo.64.a898","DOIUrl":"https://doi.org/10.2957/kanzo.64.a898","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"196 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139313833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
人名索引 人名索引
Kanzo Pub Date : 2023-10-25 DOI: 10.2957/kanzo.64.i3_1
{"title":"人名索引","authors":"","doi":"10.2957/kanzo.64.i3_1","DOIUrl":"https://doi.org/10.2957/kanzo.64.i3_1","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139314184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
一般演題 一般演題
Kanzo Pub Date : 2023-10-25 DOI: 10.2957/kanzo.64.a819
{"title":"一般演題","authors":"","doi":"10.2957/kanzo.64.a819","DOIUrl":"https://doi.org/10.2957/kanzo.64.a819","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139313946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
プログラム 计划
Kanzo Pub Date : 2023-10-25 DOI: 10.2957/kanzo.64.s3_1
{"title":"プログラム","authors":"","doi":"10.2957/kanzo.64.s3_1","DOIUrl":"https://doi.org/10.2957/kanzo.64.s3_1","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139314085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
特別講演 特別講演
Kanzo Pub Date : 2023-10-25 DOI: 10.2957/kanzo.64.a675
{"title":"特別講演","authors":"","doi":"10.2957/kanzo.64.a675","DOIUrl":"https://doi.org/10.2957/kanzo.64.a675","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139314030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
特別企画 特别企画
Kanzo Pub Date : 2023-10-25 DOI: 10.2957/kanzo.64.a793
{"title":"特別企画","authors":"","doi":"10.2957/kanzo.64.a793","DOIUrl":"https://doi.org/10.2957/kanzo.64.a793","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139313775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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