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レンバチニブ及び放射線治療後の再肝切除による集学的治療が奏功した門脈腫瘍栓を伴う早期再発肝細胞癌の1例 一例早期复发性肝细胞癌伴有门静脉瘤栓，在放疗后成功接受来伐替尼和再切除术的多模式治疗。
Kanzo Pub Date : 2023-12-01 DOI: 10.2957/kanzo.64.641
Yuta Jin, Ryo Nishiyama, Y. Koganei, Daiki Kimura, Junya Aoyama, Yutaka Nakano, Shunichi Imai, Tatsuya Shimogawara, Toru Yamada, Tomohisa Egawa
{"title":"レンバチニブ及び放射線治療後の再肝切除による集学的治療が奏功した門脈腫瘍栓を伴う早期再発肝細胞癌の1例","authors":"Yuta Jin, Ryo Nishiyama, Y. Koganei, Daiki Kimura, Junya Aoyama, Yutaka Nakano, Shunichi Imai, Tatsuya Shimogawara, Toru Yamada, Tomohisa Egawa","doi":"10.2957/kanzo.64.641","DOIUrl":"https://doi.org/10.2957/kanzo.64.641","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":" 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138615406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
母子感染予防目的で核酸アナログ製剤が投与され，出産後の中止後にB型肝炎の急性増悪を来した一例 一例因产后停用预防母婴传播的核酸类似物而导致乙型肝炎急性加重的病例。
Kanzo Pub Date : 2023-12-01 DOI: 10.2957/kanzo.64.653
Yasuki Hatayama, Harutoshi Sugiyama, Daisuke Murakami, H. Oura, Yukiko Shima, M. Shirato, Takayoshi Nishino, M. Arai, Naoya Kato
{"title":"母子感染予防目的で核酸アナログ製剤が投与され，出産後の中止後にB型肝炎の急性増悪を来した一例","authors":"Yasuki Hatayama, Harutoshi Sugiyama, Daisuke Murakami, H. Oura, Yukiko Shima, M. Shirato, Takayoshi Nishino, M. Arai, Naoya Kato","doi":"10.2957/kanzo.64.653","DOIUrl":"https://doi.org/10.2957/kanzo.64.653","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"48 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138622899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
メタノール中毒にて失明したアルコール性肝硬変の1例 一例因甲醇中毒导致失明的酒精性肝硬化病例
Kanzo Pub Date : 2023-12-01 DOI: 10.2957/kanzo.64.618
Sota Umetani, Masayuki Miyazaki, Yuichi Tachibana, Akihiro Ueda, Tetsuro Akashi
{"title":"メタノール中毒にて失明したアルコール性肝硬変の1例","authors":"Sota Umetani, Masayuki Miyazaki, Yuichi Tachibana, Akihiro Ueda, Tetsuro Akashi","doi":"10.2957/kanzo.64.618","DOIUrl":"https://doi.org/10.2957/kanzo.64.618","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"56 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139013546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
血液透析中の肝細胞癌患者に対しアテゾリズマブ＋ベバシズマブ併用療法が可能であった一例 阿特珠单抗加贝伐单抗成功治疗一例血液透析肝细胞癌病例
Kanzo Pub Date : 2023-12-01 DOI: 10.2957/kanzo.64.632
Mayu Oda, Y. Kisaka, Akiko Ogawa, Katsura Yokoyama, Kotaro Sunago, Nayu Tazuya, Yoshinori Tanaka
{"title":"血液透析中の肝細胞癌患者に対しアテゾリズマブ＋ベバシズマブ併用療法が可能であった一例","authors":"Mayu Oda, Y. Kisaka, Akiko Ogawa, Katsura Yokoyama, Kotaro Sunago, Nayu Tazuya, Yoshinori Tanaka","doi":"10.2957/kanzo.64.632","DOIUrl":"https://doi.org/10.2957/kanzo.64.632","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":" 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138620674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the impact of carryover in a fully automated, high-sensitivity hepatitis B core-related antigen assay 评估全自动高灵敏度乙型肝炎核心相关抗原测定中迁移的影响
Kanzo Pub Date : 2023-12-01 DOI: 10.2957/kanzo.64.656
K. Ohne, S. Kani, Yoshiyuki Kitamura, Haruka Sagi, Atsushi Kaneko, Minoru Ohhashi, Shohei Kikuchi, Yasuhito Tanaka, Takako Inoue
{"title":"Evaluation of the impact of carryover in a fully automated, high-sensitivity hepatitis B core-related antigen assay","authors":"K. Ohne, S. Kani, Yoshiyuki Kitamura, Haruka Sagi, Atsushi Kaneko, Minoru Ohhashi, Shohei Kikuchi, Yasuhito Tanaka, Takako Inoue","doi":"10.2957/kanzo.64.656","DOIUrl":"https://doi.org/10.2957/kanzo.64.656","url":null,"abstract":"","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138618193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Usefulness of endoscopic biliary drainage for hepatocellular carcinoma associated with obstructive jaundice 内镜下胆道引流对肝细胞癌合并梗阻性黄疸的疗效
Kanzo Pub Date : 2023-11-01 DOI: 10.2957/kanzo.64.550
Yuka Kaneko, Miyuki Kaneshiro, Hideki Watanabe
{"title":"Usefulness of endoscopic biliary drainage for hepatocellular carcinoma associated with obstructive jaundice","authors":"Yuka Kaneko, Miyuki Kaneshiro, Hideki Watanabe","doi":"10.2957/kanzo.64.550","DOIUrl":"https://doi.org/10.2957/kanzo.64.550","url":null,"abstract":"胆管浸潤や胆管圧排による閉塞性黄疸を伴う肝細胞癌に対する内視鏡的胆道ドレナージの有効性について検討した．2008年1月から2023年3月までに閉塞性黄疸を呈した肝細胞癌は20例だった．男性16例，女性4例で，平均年齢は75±8歳，門脈浸潤は，Vp0/Vp2/Vp3＝13/3/4例，ステント挿入例は16例であった．閉塞性黄疸の改善の有無で全生存期間（OS）を比較すると，黄疸改善例では良好なOSを認めた（p＜0.001）．プラスチックステント7例，自己拡張型金属ステント9例で両者のOSに明らかな有意差を認めなかった（p=0.218）．ドレナージ前後のT.Bil値で有意差を認めた（p=0.001）．肝予備能の低下した進行期の肝細胞癌の閉塞性黄疸に対する内視鏡的胆道ドレナージは有用であり，患者の全身状態を考慮しながら検討すべきである．","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"118 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135565169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
肝炎医療コーディネーター活動継続における肝疾患診療連携拠点病院の役割 肝炎医疗协调员持续活动中的肝病诊疗协作据点医院的作用
Kanzo Pub Date : 2023-11-01 DOI: 10.2957/kanzo.64.583
Hiroko Setoyama, Maki Nomura, Tomomi Yada, Yoko Yoshimaru, Satoshi Narahara, Hiroki Inada, Kentaro Tanaka, Sotaro Kurano, Takayuki Tokunaga, Etsuko Iio, Katsuya Nagaoka, Takehisa Watanabe, Yuichiro Eguchi, Yasuhito Tanaka
{"title":"肝炎医療コーディネーター活動継続における肝疾患診療連携拠点病院の役割","authors":"Hiroko Setoyama, Maki Nomura, Tomomi Yada, Yoko Yoshimaru, Satoshi Narahara, Hiroki Inada, Kentaro Tanaka, Sotaro Kurano, Takayuki Tokunaga, Etsuko Iio, Katsuya Nagaoka, Takehisa Watanabe, Yuichiro Eguchi, Yasuhito Tanaka","doi":"10.2957/kanzo.64.583","DOIUrl":"https://doi.org/10.2957/kanzo.64.583","url":null,"abstract":"Continuation of activities is important for the hepatitis medical care coordinators to fulfill their functions, which must be supported by regional core centers for liver disease management. Thus, we conducted a questionnaire survey among coordinators in Kumamoto Prefecture to identify factors that motivates them to continue their activities. Results showed that coordinators were mainly motivated by a sense of social contribution. The factors considered important in the continuation of their activities are self-evaluation and of others, resolution of concerns about their activities, and the presence of peers/consultants. The regional core centers should actively provide a place and means for the coordinators to be active.","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"118 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135565170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
病理組織学的なMetastatic carcinomatous cirrhosisをきたした浸潤性小葉癌の1症例 造成组织病理学Metastatic carcinomatous cirrhosis的1个浸润性小叶癌病例
Kanzo Pub Date : 2023-11-01 DOI: 10.2957/kanzo.64.575
Soo Ryang Kim, Soo Ki Kim, Hisato Kobayashi, Toyokazu Okuda, Atsushi Nakai, Yumi Fujii, Takanobu Hayakumo, Motoko Sasaki, Yu-ichiro Koma, Akira Asai, Hiroki Nishikawa
{"title":"病理組織学的なMetastatic carcinomatous cirrhosisをきたした浸潤性小葉癌の1症例","authors":"Soo Ryang Kim, Soo Ki Kim, Hisato Kobayashi, Toyokazu Okuda, Atsushi Nakai, Yumi Fujii, Takanobu Hayakumo, Motoko Sasaki, Yu-ichiro Koma, Akira Asai, Hiroki Nishikawa","doi":"10.2957/kanzo.64.575","DOIUrl":"https://doi.org/10.2957/kanzo.64.575","url":null,"abstract":"症例は60歳代女性．X年2月乳癌の診断のもと，左乳房切除，病理所見は浸潤性小葉癌であった．同年3月に多発リンパ節，骨転移に対して薬物療法を開始したが，8月より肝障害が出現した．薬剤性肝障害を疑い，薬物治療を中止するも肝障害は増悪した．造影CT，EOB-MRIなどの画像診断で肝転移巣は認めなかったが，腫瘍マーカーCA15-3の上昇がみられた．10月に腹部超音波カラードップラー画像・ソナゾイド造影所見から類洞閉塞などによる門脈血流低下が示唆された．経頸静脈的肝生検を施行したところ，類洞内に浸潤性小葉癌転移と肝硬変様の高度線維化を認めた．","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135565178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
肝炎ウイルス陽性者対策が急がれる非肝臓専門科は？ 肝炎病毒阳性者对策迫在眉睫的非肝脏专科是?
Kanzo Pub Date : 2023-11-01 DOI: 10.2957/kanzo.64.587
Kenichi Hirota, Takako Inoue, Koji Ogawa, Yoshihisa Arao, Mizuki Endo, Tadashi Ikegami, Hiroki Tojima, Atsushi Suetsugu, Satoru Kakizaki, Hiroko Setoyama, Masaru Enomoto, Masaaki Korenaga
{"title":"肝炎ウイルス陽性者対策が急がれる非肝臓専門科は？","authors":"Kenichi Hirota, Takako Inoue, Koji Ogawa, Yoshihisa Arao, Mizuki Endo, Tadashi Ikegami, Hiroki Tojima, Atsushi Suetsugu, Satoru Kakizaki, Hiroko Setoyama, Masaru Enomoto, Masaaki Korenaga","doi":"10.2957/kanzo.64.587","DOIUrl":"https://doi.org/10.2957/kanzo.64.587","url":null,"abstract":"In eight regional core centers for liver disease management, we evaluated the status of HBs antigen (HBsAg) and anti-hepatitis C virus antibody (anti-HCV) testing from 2016 to 2020. Among nonhepatology departments, ophthalmology had the highest number of HBsAg and anti-HCV tests, followed by obstetrics and gynecology, and orthopedics. The highest positive rates of HBsAg were in orthopedics (1.27%), gastroenterological surgery (1.23%), and ophthalmology (1.04%), and those of anti-HCV were in gastroenterological surgery (2.71%), orthopedics (2.57%), and ophthalmology (2.51%). Thus, ophthalmology and orthopedics obtained the highest number of tests and positive rates, with no rate decrease over time. While the Japan Ophthalmologists Association has already commercialized measures against hepatitis, similar measures are needed urgently in orthopedics.","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"120 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135565163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
アテゾリズマブ・ベバシズマブ併用療法後自己免疫性脳炎を発症し，改善後に2次治療に移行した肝細胞癌の1例 阿替唑单抗-贝伐西单抗联合疗法后发生自身免疫性脑炎，改善后转入二线治疗的肝细胞癌1例
Kanzo Pub Date : 2023-11-01 DOI: 10.2957/kanzo.64.559
Takahiro Osuga, Koji Miyanishi, Ryo Ito, Shingo Tanaka, Tomohiro Kubo, Kota Hamaguchi, Hiroyuki Ohnuma, Kazuyuki Murase, Kohichi Takada, Morihiro Yamamoto, Tatsuo Manabe, Shin Hisahara, Junji Kato
{"title":"アテゾリズマブ・ベバシズマブ併用療法後自己免疫性脳炎を発症し，改善後に2次治療に移行した肝細胞癌の1例","authors":"Takahiro Osuga, Koji Miyanishi, Ryo Ito, Shingo Tanaka, Tomohiro Kubo, Kota Hamaguchi, Hiroyuki Ohnuma, Kazuyuki Murase, Kohichi Takada, Morihiro Yamamoto, Tatsuo Manabe, Shin Hisahara, Junji Kato","doi":"10.2957/kanzo.64.559","DOIUrl":"https://doi.org/10.2957/kanzo.64.559","url":null,"abstract":"68歳，男性．右背部痛を主訴に近医受診，肝腫瘤を指摘され当院紹介．肝細胞癌，多発リンパ節・骨転移と診断し，アテゾリズマブ・ベバシズマブ併用療法（ATZ＋BV）を開始した．投与開始14日目に辻褄の合わない言動と傾眠，16日目にJCS10の意識障害を認めた．血中アンモニア値，頭部MRIに異常なく，髄液検査では僅かな細胞数上昇と蛋白細胞解離を認めた．自己免疫性脳炎を疑い，同日よりステロイドパルス療法を開始した．意識障害は著明に改善し，内服ステロイドに移行後，38日目に後遺症なく自宅退院となった．脳炎の再燃はなく，ATZ＋BV開始60日目に2次治療としてレンバチニブを導入した．肝細胞癌に対するATZ＋BV後の自己免疫性脳炎は，自験例を含め4例のみ報告されており，初発症状や意識障害出現時期がほぼ一致していた．早期の診断とステロイドパルス療法施行により2次治療へ移行できた症例であると考えられた．","PeriodicalId":17925,"journal":{"name":"Kanzo","volume":"120 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135565166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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