Klinische Monatsblatter fur Augenheilkunde最新文献_第9页

Effects of Air Pollution and Meteorological Conditions on DED: Associated Manifestations and Underlying Mechanisms. 空气污染和气象条件对 DED 的影响：相关表现和内在机制。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2024-09-01 Epub Date: 2024-04-30 DOI: 10.1055/a-2316-6808

Hui-Zhong Zhou, Xiufen Liu, Dandan Zhou, Fei Shao, Qian Li, Dan Li, Tianlong He, Yu Ren, Cheng-Wei Lu

引用次数: 0

[Iatrogenic Retinal Artery Occlusions Following Retrobulbar Anaesthesia]. [Retrobulbar 麻醉后的先天性视网膜动脉闭塞症]。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2024-09-01 Epub Date: 2024-03-26 DOI: 10.1055/a-2244-5449

Mohamed El-Jade

引用次数: 0

[The 2021 Activity Report of the Tissue Transplantation and Biotechnology Section of the German Ophthalmological Society]. [德国眼科学会组织移植和生物技术分会 2021 年活动报告]。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2024-09-01 Epub Date: 2023-05-05 DOI: 10.1055/a-2062-3699

Helga Reinshagen, Daniel Böhringer, Jan Schroeter, Philip Christian Maier

引用次数: 0

Eplerenone for the Treatment of Chronic Recurrent Chorioretinopathy Centralis Serosa. 依普利酮治疗慢性复发性中央浆膜脉络膜视网膜病变。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2024-09-01 Epub Date: 2023-09-05 DOI: 10.1055/a-2105-0892

Lisa-Marie Herrmann, Egbert Matthé, Dirk Sandner, Dierk Wittig

{"title":"Eplerenone for the Treatment of Chronic Recurrent Chorioretinopathy Centralis Serosa.","authors":"Lisa-Marie Herrmann, Egbert Matthé, Dirk Sandner, Dierk Wittig","doi":"10.1055/a-2105-0892","DOIUrl":"10.1055/a-2105-0892","url":null,"abstract":"Background: Chorioretinopathy centralis serosa (CCS) is a common disease that leads to the loss of retinal ion/fluid homeostasis due to decompensation of the retinal pigment epithelium, resulting in fluid accumulation with detachment of the neurosensory retina and/or retinal pigment epithelium. We investigated the effect of eplerenone, a mineralocorticoid receptor inhibitor, on chronic recurrent CCS (cr-CCS).Methods: A retrospective study with data analysis of 17 eyes (12 patients) between 2014 - 2021 with cr-CCS in whom other methods were not effective, not applicable, or not desired, was performed. Duration of CCS was at least 12 months with at least one recurrence. Each patient received 25 mg (1st week) and 50 mg (from the 2nd week) for at least 3 months. In each case, best-corrected visual acuity and central and peripheral retinal thickness were measured by spectral-domain optical coherence tomography. Side effects were rated by the patients as \"none\", \"mild\" (noticeable but not affecting), \"tolerable\" (affecting but acceptable because of good effect), and \"not tolerable\" (then discontinuation of therapy).Results: There was no significant reduction in central or peripheral retinal thickness. A complete reduction of subretinal fluid was achieved in 5 of 17 eyes (29.4%). In 12 eyes, no effect of eplerenone could be detected, so other therapies were required. Visual acuity change was mainly dependent on the duration of CCS and the degree of photoreceptor damage. Side effects were reported by 11 patients as \"none\" and 1 patient as \"mild\" (arterial hypotension). No other side effects were observed.Conclusion: The response rates of therapy with eplerenone were relatively low, and no significant effect could be demonstrated. Eplerenone should not (no longer) be routinely used in the therapy of cr-CCS.","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"1039-1043"},"PeriodicalIF":0.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10161181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy, Confounders and Safety of the Preserflo Microshunt. Preserflo 微分流术的疗效、并发症和安全性

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2024-09-01 Epub Date: 2024-07-24 DOI: 10.1055/a-2325-9286

Cemre Altas, Thomas A Fuchsluger, Tobias Brockmann, Anna Graumüller, Marcus Walckling

{"title":"Efficacy, Confounders and Safety of the Preserflo Microshunt.","authors":"Cemre Altas, Thomas A Fuchsluger, Tobias Brockmann, Anna Graumüller, Marcus Walckling","doi":"10.1055/a-2325-9286","DOIUrl":"10.1055/a-2325-9286","url":null,"abstract":"Background: Glaucoma is a leading cause of blindness worldwide. We evaluated the efficacy, confounders, and safety of the Preserflo Microshunt over a one-year follow-up period.Methods: In this retrospective monocentric study, 111 eyes were evaluated. 83 eyes had primary open angle glaucoma, and 28 eyes secondary open angle glaucoma. Intraocular pressure (IOP), visual acuity, number of glaucoma medications, complications, and reoperations were evaluated postoperatively, at 1, 3, 6, 9, and 12 months. The influence of age, sex, type of glaucoma, previous surgery and lens status was also analysed. Bleb revision was indicated if corrected IOP exceeded 18 mmHg.Results: Intraocular pressure significantly decreased from 24.50 ± 8.94 to 14.62 ± 4.86 mmHg (4 - 32 mmHg; p < 0.001), the number of medications from 3.19 ± 1.14 to 0.98 ± 1.39 (0 - 4; p < 0.001). Confounders of interest did not affect efficacy. Bleb revision was performed in 22.5% of eyes and a cyclophotocoagulation was performed in 9.9% of eyes. Complete surgical success (IOP ≤ 17 mmHg, IOP reduction ≥ 20%, without medication) was achieved in 36.9% (n = 41) and qualified success (with medication) in 51.4% (n = 57) of eyes. Transient hypotension (≤ 5 mmHg) occurred in 19.8% after primary implantation and in 1.8% after bleb revision (duration ≤ 3 months).Conclusion: To date, the Preserflo Microshunt has demonstrated good efficacy and a low risk profile.","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"1048-1056"},"PeriodicalIF":0.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141759576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Idiopathic Blind Spot Enlargement Syndrome (AIBSES) in the Era of OCT - a Review. OCT 时代的急性特发性盲点扩大综合征 (AIBSES) - 综述。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2024-09-01 Epub Date: 2023-09-07 DOI: 10.1055/a-2130-5131

Julian Alexander Zimmermann, Julia Biermann

引用次数: 0

Glucagon-like Peptide 1 Receptor Agonist: Balancing Alarm and Caution. 胰高血糖素样肽 1 受体激动剂：警惕与谨慎之间的平衡。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2024-09-01 Epub Date: 2024-09-16 DOI: 10.1055/a-2369-9085

Focke Ziemssen, Hans-Peter Hammes, Horst Helbig

引用次数: 0

Role of Artificial Intelligence in Retinal Diseases. 人工智能在视网膜疾病中的作用。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2024-09-01 Epub Date: 2024-09-16 DOI: 10.1055/a-2378-6138

Julia Mai, Ursula Schmidt-Erfurth

{"title":"Role of Artificial Intelligence in Retinal Diseases.","authors":"Julia Mai, Ursula Schmidt-Erfurth","doi":"10.1055/a-2378-6138","DOIUrl":"https://doi.org/10.1055/a-2378-6138","url":null,"abstract":"Artificial intelligence (AI) has already found its way into ophthalmology, with the first approved algorithms that can be used in clinical routine. Retinal diseases in particular are proving to be an important area of application for AI, as they are the main cause of blindness and the number of patients suffering from retinal diseases is constantly increasing. At the same time, regular imaging using high-resolution modalities in a standardised and reproducible manner generates immense amounts of data that can hardly be processed by human experts. In addition, ophthalmology is constantly experiencing new developments and breakthroughs that require a re-evaluation of patient management in routine clinical practice. AI is able to analyse these volumes of data efficiently and objectively and also provide new insights into disease progression and therapeutic mechanisms by identifying relevant biomarkers. AI can make a significant contribution to screening, classification and prognosis of various retinal diseases and can ultimately be a clinical decision support system, that significantly reduces the burden on both everyday clinical practice and the healthcare system, by making more efficient use of costly and time-consuming resources.","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":"241 9","pages":"1023-1031"},"PeriodicalIF":0.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11405099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conjunctival Histopathological Changes and Clinical Tear Film in Children with Atopic Dermatitis. 特应性皮炎患儿结膜和临床泪膜的组织病理学变化。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2024-08-27 DOI: 10.1055/a-2376-3114

Alper Halil Bayat, Gozde Aksoy Aydemir, Emre Aydemir, Haci Hasan Özkan, Gürkan Yardimci, Bilge Aydin Türk, Emine Özkul Kilinç

{"title":"Conjunctival Histopathological Changes and Clinical Tear Film in Children with Atopic Dermatitis.","authors":"Alper Halil Bayat, Gozde Aksoy Aydemir, Emre Aydemir, Haci Hasan Özkan, Gürkan Yardimci, Bilge Aydin Türk, Emine Özkul Kilinç","doi":"10.1055/a-2376-3114","DOIUrl":"10.1055/a-2376-3114","url":null,"abstract":"Purpose: Evaluation of changes in the ocular surfaces in children with a diagnosis of atopic dermatitis (AD).Methods: Thirty-six children with a diagnosis of AD (Eye-AD group) and 40 healthy subjects (Eye-HS group) were enrolled in this prospective case-control study. Tear film break-up time (T-BUT), Schirmer tear test (STT), conjunctival impression cytology (CIC), tear meniscus height (TMH), tear meniscus area (TMA), and ocular surface disease index (OSDI) were measured.Results: The participants were similar in terms of demographic characteristics, such as mean age and gender (p > 0.05). The mean T-BUT was 9.3 ± 2.22 s (5 - 16) in the Eye-AD group and 11.83 ± 2.03 s (7 - 16) in the Eye-HS group. The mean STT was 11.12 ± 3.28 mm (5 - 21) in the Eye-AD group and 15.44 ± 3.8 mm (8 - 20) in the Eye-HS group (p < 0.001, p < 0.001, respectively). The mean OSDI scores were 13.12 ± 1.41 (10 - 15) in the Eye-AD group and 13.97 ± 2.93 (8 - 20) in the Eye-HS group (p = 0.052). Mean TMH and TMA were 306.48 ± 7.29 µm and 0.22 ± 0.004 mm2, respectively, in the Eye-AD group, and 312.94 ± 5.31 µm and 0.027 ± 0.005 mm2, respectively, in the Eye-HS group. In the CIC analyses, 22 of the samples in the Eye-AD group and 35 in the Eye-HS group had a classification of grade 0, 10 in the Eye-AD group and 5 in the Eye-HS group had a classification of grade 1, and 4 in the Eye-AD group and none in the Eye-HS group had a classification of grade 2 (p = 0.015).Conclusion: Pediatric patients with AD may have significant changes in conjunctival histopathology. These changes can be manifested in the tests used to measure the tear film. Dry eye was shown to be present in the majority of children with AD.","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The Orbital Apex - Dangerous Terrain!] [轨道顶点--危险地形！]

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2024-08-27 DOI: 10.1055/a-2378-5330

Kathrin Marie Grimm, Isabella Diana Baur, Arthur Mueller, Josef Märtz

引用次数: 0