Klinische Monatsblatter fur Augenheilkunde最新文献

{"title":"Dissolve or Evaporate: an Update to Treatment Modalities in Band-like Keratopathy.","authors":"Tonio Felix Schaffert, Daniel Böhringer, Thomas Reinhard, Philip Christian Maier","doi":"10.1055/a-2760-3432","DOIUrl":"10.1055/a-2760-3432","url":null,"abstract":"<p><strong>Abstract: </strong>BACKGROUND: Treatment modalities for band keratopathy (BK), which consists of calcium phosphate deposits in Bowman's layer and upper corneal stromal lamellae, are ethylenediamine tetraacetate (EDTA) chelation and phototherapeutic keratectomy (PTK). In this retrospective study, we compared the effectiveness and the recurrence rate for both methods.</p><p><strong>Abstract: </strong>PATIENTS/MATERIAL AND METHODS: We conducted a retrospective study of patients with idiopathic BK who had been treated with EDTA-chelation or PTK and who had no other relevant corneal disease. Of 81 patients, 34 were treated with EDTA chelation and 47 with PTK. Demographic data, comorbidities, pre- and postoperative visual acuity, preoperative severity of the disease and technical surgical parameters were recorded. The results were compared descriptively. A telephone survey was conducted to investigate the subjective outcome after surgery and the development of recurrences.</p><p><strong>Abstract: </strong>RESULTS: Regardless of the preoperative severity of BK, treatment intensity and comorbidities, this study confirmed an equal improvement in visual acuity with both EDTA chelation and PTK. The telephone survey showed that the recurrence rate after PTK was significantly lower than after EDTA-chelation (chi-square = 4.74; p = 0.03, n = 25). However, the postoperative symptomatic relief was similar in both groups.</p><p><strong>Abstract: </strong>CONCLUSION: EDTA chelation and PTK as treatment of BK provide equivalent improvement in visual acuity and postoperative symptomatic relief. A lower recurrence rate may be expected with PTK. Further prospective studies would be necessary to confirm our results.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"697-703"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146181115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Closure of Full-Thickness Macular Hole in a Patient with Retinal Arteriovenous Malformation: Sixteen-Year Follow-up.","authors":"Zeynep Serikoglu Akbas, Faik Gelisken, Benedikt Rössler","doi":"10.1055/a-2550-0839","DOIUrl":"10.1055/a-2550-0839","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"684-686"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13278787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal Allogeneic Intrastromal Ring Segments (CAIRS): Indications, Mechanism of Action and Outcomes.","authors":"Friedrich Steindor, Robert Bock, Michal Cieplucha, Theo G Seiler, Gerd Geerling","doi":"10.1055/a-2874-7387","DOIUrl":"10.1055/a-2874-7387","url":null,"abstract":"<p><strong>Abstract: </strong>Keratoconus is a progressive corneal ectasia, characterised by stromal thinning, conical protrusion and irregular astigmatism. While conservative measures and contact lenses are sufficient in early stage, advanced cases require surgical intervention. Corneal allogeneic intrastromal ring segments (CAIRS) represent a novel approach: donor tissue is transplanted (\"keratoplasty\") into the corneal stroma, leading to flattening of the cone, regularisation of the corneal surface and improvement in visual acuity. Since their first description by Jacob et al. in 2018 worldwide experience has grown.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"649-653"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147874721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Diagnostic Approaches to the Cornea (Part 2) - From Conventional Techniques to Advanced Imaging].","authors":"Klemens P Kaiser, Mehdi Shajari, Loay Daas, Thomas Kohnen","doi":"10.1055/a-2769-0874","DOIUrl":"10.1055/a-2769-0874","url":null,"abstract":"<p><strong>Abstract: </strong>The cornea plays a pivotal role in visual quality, accounting for most of the eye's refractive power. It is also frequently affected by a wide range of pathological conditions. Accurate diagnostics are therefore fundamental for making therapeutic decisions. This review provides an overview of established and emerging methods for examining the cornea, ranging from corneal pachymetry, assessments of the endothelium and nerves, anterior segment optical coherence tomography, and biomechanical measurements. Advances in high-resolution imaging and multimodal platforms have significantly improved the early detection of disease, risk stratification and monitoring. Furthermore, AI-supported multimodal approaches integrate topo-/tomography data for personalized risk assessment and mark the future of corneal diagnostics.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"705-717"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146213440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The 2023 Activity Report of the Tissue Transplantation and Biotechnology Section of the German Ophthalmological Society].","authors":"Helga Reinshagen, Daniel Böhringer, Jan Schroeter, Philip Christian Maier","doi":"10.1055/a-2521-3969","DOIUrl":"10.1055/a-2521-3969","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"674-678"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of a Prolonged Postoperative Steroid Regimen on the Incidence of New Intraretinal Cystoid Changes after Vitrectomy and Membrane Peeling for Epiretinal Membranes.","authors":"Christoph Leisser, Alexandros Anastassiuou, Stefan Palkovits, Oliver Findl","doi":"10.1055/a-2798-3269","DOIUrl":"10.1055/a-2798-3269","url":null,"abstract":"<p><strong>Abstract: </strong>BACKGROUND: Epiretinal membranes are a macular disorder leading to metamorphopsia and a decrease in visual acuity. Peeling of epiretinal membranes is associated with a risk for development of new intraretinal cystoid changes after surgery - in about 10% of patients. In our study we analyzed the occurrence of new intraretinal cystoid changes after vitrectomy with membrane peeling with respect to prolonged application of steroidal eye drops after surgery, compared to a historical group of patients.</p><p><strong>Abstract: </strong>METHODS: This retrospective study included patients scheduled for pars plana vitrectomy with membrane peeling due to an idiopathic epiretinal membrane. All patients underwent prolonged postoperative treatment with steroidal eye drops for 3 months (study group) or 4 weeks (historical group). Patients in the historical group were matched in a 1 : 1 fashion to patients in the study group, using propensity scores.</p><p><strong>Abstract: </strong>RESULTS: In total, 114 patients were included into the study group and 114 patients were selected from the historical group, according to the matching procedure. New postoperative intraretinal cystoid changes were present in 6% (n = 7) of patients in the study population and in 17% (n = 19) in the historical control group. In comparison with the subgroups of patients without intraretinal cystoid changes before surgery, new postoperative intraretinal cystoid changes developed significantly less often in the study group (p = 0.02, 95% confidence interval: - 0.27, - 0.02, chi square test). The odds ratio of development of new postoperative intraretinal cystoid changes in the study group, compared to the historical group, was 0.35 (95% confidence interval: 0.14, 0.88). There were no comparable effects of a prolonged treatment with steroidal eye drops with respect to postoperative resorption of preoperative intraretinal cystoid changes.</p><p><strong>Abstract: </strong>CONCLUSIONS: In this retrospective study, prolonged postoperative steroid eye drop therapy was associated with a lower incidence of newly developed postoperative intraretinal cystoid changes, compared to a historical group of patients.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":"243 6","pages":"687-696"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148277858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Adjuvant Crosslinking to Improve Graft Survival after High-Risk Keratoplasty - A Case Series from the CrossCornealVision Study].","authors":"Johanna Wiedemann, Deniz Hos, Florian Thomas Steinberg, Simona Schlereth, Björn O Bachmann, Tina Dietrich-Ntoukas, Gerd Geerling, Daniel Böhringer, Berthold Seitz, Nikolaus Luft, Claus Cursiefen","doi":"10.1055/a-2870-2234","DOIUrl":"10.1055/a-2870-2234","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"669-673"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovationen in der Hornhautchirurgie – von der individualisierten CAIRS-Keratoplastik bis zur lamellären Keratoprothese.","authors":"Gerd Geerling, Philip Christian Maier, Berthold Seitz","doi":"10.1055/a-2754-8604","DOIUrl":"https://doi.org/10.1055/a-2754-8604","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":"243 6","pages":"647-648"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148277844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interface Between Ophthalmology and Rheumatology in Uveitis and Retinal Vasculitis in Adult Patients, When Does Who Need Whom?","authors":"Ina Kötter, Nicole Stübiger, Christoph Deuter","doi":"10.1055/a-2854-8192","DOIUrl":"10.1055/a-2854-8192","url":null,"abstract":"<p><strong>Abstract: </strong>BACKGROUND: There is a significant interface between ophthalmology and rheumatology, particularly in uveitis and retinal vasculitis. This will be described in detail here.</p><p><strong>Abstract: </strong>RESULTS: Analyses of uveitis consultations from university centres in Austria and Germany show that approximately 30% of anterior uveitis cases, 17% of intermediate and posterior uveitis cases, 7% of panuveitis cases, and 20% of retinal vasculitis cases, are associated with an inflammatory rheumatic systemic disease. The most frequent association (30%) is between spondyloarthritis and psoriatic arthritis with anterior uveitis (AAU). In approximately 1.3% of cases of intermediate uveitis, sarcoidosis is present, while in posterior uveitis and panuveitis, Behcet's syndrome (BS) is the most likely cause (2.5% and 12.6%, respectively). Retinal vasculitis is associated with BS in 18% of cases. Easily detectable \"red flags\" for inflammatory rheumatic diseases and the influence of uveitis on systemic immunomodulatory therapy in rheumatology have been described. For example, in AAU during SPA, monoclonal tumour necrosis factor inhibitors (TNFi) are more effective than etanercept, a fusion protein of the TNF receptor and immunoglobulin Fc segment. IL-17 antagonists and Janus-Kinase (JAK) inhibitors are also able to reduce the risk of uveitis flares, but are less effective than monoclonal TNFi.</p><p><strong>Abstract: </strong>SUMMARY: Close collaboration between rheumatologists and ophthalmologists is essential, particularly in the treatment of uveitis and retinal vasculitis. Assessment for certain warning signs and determination of specific laboratory parameters are helpful in detecting the association, present in approximately 20% of cases, between uveitis and retinal vasculitis and inflammatory rheumatic systemic diseases, and in referring patients specifically to rheumatology. Conversely, rheumatologists require precise ophthalmological findings and information on treatment response, in order to adjust therapy in a targeted manner or, in cases of ocular symptoms associated with an underlying inflammatory systemic disease, in order to appropriately adapt the therapy to the ocular involvement.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":"243 5","pages":"584-589"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147973463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Inflammatory Eye Diseases].","authors":"Arnd Heiligenhaus, Claus Cursiefen","doi":"10.1055/a-2754-8358","DOIUrl":"https://doi.org/10.1055/a-2754-8358","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":"243 5","pages":"569-570"},"PeriodicalIF":0.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147973351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}