Korean Circulation Journal最新文献

{"title":"Mitral Annular Tissue Velocity Predicts Survival in Patients With Primary Mitral Regurgitation.","authors":"You-Jung Choi, Chan Soon Park, Tae-Min Rhee, Hyun-Jung Lee, Hong-Mi Choi, In-Chang Hwang, Jun-Bean Park, Yeonyee E Yoon, Jin Oh Na, Hyung-Kwan Kim, Yong-Jin Kim, Goo-Yeong Cho, Dae-Won Sohn, Seung-Pyo Lee","doi":"10.4070/kcj.2023.0292","DOIUrl":"10.4070/kcj.2023.0292","url":null,"abstract":"<p><strong>Background and objectives: </strong>Early diastolic mitral annular tissue (e') velocity is a commonly used marker of left ventricular (LV) diastolic function. This study aimed to investigate the prognostic implications of e' velocity in patients with mitral regurgitation (MR).</p><p><strong>Methods: </strong>This retrospective cohort study included 1,536 consecutive patients aged <65 years with moderate or severe chronic primary MR diagnosed between 2009 and 2018. The primary and secondary outcomes were all-cause and cardiovascular mortality, respectively. According to the current guidelines, the cut-off value of e' velocity was defined as 7 cm/s.</p><p><strong>Results: </strong>A total of 404 individuals were enrolled (median age, 51.0 years; 64.1% male; 47.8% severe MR). During a median 6.0-year follow-up, there were 40 all-cause mortality and 16 cardiovascular deaths. Multivariate analysis revealed a significant association between e' velocity and all-cause death (adjusted hazard ratio [aHR], 0.770; 95% confidence interval [CI], 0.634-0.935; p=0.008) and cardiovascular death (aHR, 0.690; 95% CI, 0.477-0.998; p=0.049). Abnormal e' velocity (≤7 cm/s) independently predicted all-cause death (aHR, 2.467; 95% CI, 1.170-5.200; p=0.018) and cardiovascular death (aHR, 5.021; 95% CI, 1.189-21.211; p=0.028), regardless of symptoms, LV dimension and ejection fraction. Subgroup analysis according to sex, MR severity, mitral valve replacement/repair, and symptoms, showed no significant interactions. Including e' velocity in the 10-year risk score improved reclassification for mortality (net reclassification improvement [NRI], 0.154; 95% CI, 0.308-0.910; p<0.001) and cardiovascular death (NRI, 1.018; 95% CI, 0.680-1.356; p<0.001).</p><p><strong>Conclusions: </strong>In patients aged <65 years with primary MR, e' velocity served as an independent predictor of all-cause and cardiovascular deaths.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":"54 6","pages":"311-322"},"PeriodicalIF":2.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11169913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141306198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aneroid Auscultatory Sphygmomanometers and Automated Oscillometric Devices as Mercury-Free Alternatives in Children.","authors":"Young Hwan Song","doi":"10.4070/kcj.2024.0115","DOIUrl":"10.4070/kcj.2024.0115","url":null,"abstract":"","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":"54 5","pages":"288-290"},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11109841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141065743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous Left Atrial Appendage (LAA) Occlusion With Gigantic LAA Using a Custom-Manufactured LAmbre Device.","authors":"Yangyoun Lee, Iksung Cho, Jung-Sun Kim","doi":"10.4070/kcj.2024.0014","DOIUrl":"10.4070/kcj.2024.0014","url":null,"abstract":"","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":"54 5","pages":"291-293"},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11109835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141065825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiomyocyte Autophagy: A Novel Therapeutic Target by LncRNA PART1.","authors":"Yong Sook Kim","doi":"10.4070/kcj.2024.0114","DOIUrl":"10.4070/kcj.2024.0114","url":null,"abstract":"","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":"54 5","pages":"253-255"},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11109836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141065822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Replacing Mercury Sphygmomanometers With Mercury-Free Sphygmomanometers for the National Health Survey in Children: Direct Comparisons Applying Two Types of Mercury-Free Sphygmomanometer.","authors":"Sung Hye Kim, Yu-Mi Kim, Seong Heon Kim, Jinho Shin, Eun Mi Lee","doi":"10.4070/kcj.2023.0274","DOIUrl":"10.4070/kcj.2023.0274","url":null,"abstract":"<p><strong>Background and objectives: </strong>Blood pressure (BP) measurement using an auscultatory sphygmomanometer is recommended for diagnosing hypertension in children. As mercury sphygmomanometers (MSs) are banned owing to environmental concerns, it is crucial to determine the accuracy of mercury-free sphygmomanometers to replace them. We analyzed the accuracy of these devices to guide the National Survey selection.</p><p><strong>Methods: </strong>BP was measured thrice each with MS, auscultatory device (AD), and oscillometric device (OD) in 104 participants aged 10-18 using the National Survey data. The difference in BP was defined as the difference between MS and other devices. The BP differences, correlations, and influencing factors were analyzed. The frequencies of hypertension were also compared.</p><p><strong>Results: </strong>Systolic BP (SBP) and diastolic BP (DBP) differences between MS and AD were 0.88±3.36 mmHg and 0.63±3.95 mmHg, and those between MS and OD were 0.43±5.83 mmHg and 4.57±6.89 mmHg, respectively. The absolute error of <10 mmHg for DBP between MS and OD was 76%. The concordance correlation coefficient between MS and AD was 0.94 for SBP and 0.90 for DBP, and 0.81 and 0.67, respectively for MS and OD. Arm circumference negatively correlated with BP differences except for SBP between the MS and OD. The frequency of hypertension was not different between MS and AD but was underestimated by OD.</p><p><strong>Conclusions: </strong>AD correlated well with MS, while OD did not, especially for DBP. The superiority of AD over OD suggests AD as a possible alternative for MS in the National Survey.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":"54 5","pages":"270-287"},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11109839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141065831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Intertwined Relationship Between Heart Failure and Atrial Fibrillation, How Can We Untangle It?","authors":"Ran Heo","doi":"10.4070/kcj.2024.0099","DOIUrl":"10.4070/kcj.2024.0099","url":null,"abstract":"","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":"54 5","pages":"268-269"},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11109838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141065836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association of CHADS-P2A2RC Risk Score With Clinical Outcomes in Patients Taking P2Y12 Inhibitor Monotherapy After 3 Months of Dual Antiplatelet Therapy Following Percutaneous Coronary Intervention.","authors":"Pil Sang Song, Seok-Woo Seong, Ji-Yeon Kim, Soo Yeon An, Mi Joo Kim, Kye Taek Ahn, Seon-Ah Jin, Jin-Ok Jeong, Jeong Hoon Yang, Joo-Yong Hahn, Hyeon-Cheol Gwon, Woo Jin Jang, Hyuck Jun Yoon, Jang-Whan Bae, Woong Gil Choi, Young Bin Song","doi":"10.4070/kcj.2023.0268","DOIUrl":"https://doi.org/10.4070/kcj.2023.0268","url":null,"abstract":"Concerns remain that early aspirin cessation may be associated with potential harm in subsets at high risk of ischemic events. This study aimed to assess the effects of P2Y12 inhibitor monotherapy after 3-month dual antiplatelet therapy (DAPT) vs. prolonged DAPT (12-month or longer) based on the ischemic risk stratification, the CHADS-P2A2RC, after percutaneous coronary intervention (PCI).","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":"21 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140806307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Radiofrequency Catheter Ablation for Atrial Fibrillation on Right Ventricular Function.","authors":"Minkwan Kim, Jae-Sun Uhm, Je-Wook Park, SungA Bae, In Hyun Jung, Seok-Jae Heo, Daehoon Kim, Hee Tae Yu, Tae-Hoon Kim, Boyoung Joung, Moon-Hyoung Lee","doi":"10.4070/kcj.2023.0312","DOIUrl":"https://doi.org/10.4070/kcj.2023.0312","url":null,"abstract":"The effects of radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF) on right ventricular (RV) function are not well known.","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":"12 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140800760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dronedarone Attenuates Ang II-Induced Myocardial Hypertrophy Through Regulating SIRT1/FOXO3/PKIA Axis.","authors":"Cheng Chen, Song Hu, Heng-Jing Hu, Zhi-Xuan Liu, Xin-Teng Wu, Tao Zou, Hua Su","doi":"10.4070/kcj.2023.0197","DOIUrl":"https://doi.org/10.4070/kcj.2023.0197","url":null,"abstract":"Long-term pathological myocardial hypertrophy (MH) seriously affects the normal function of the heart. Dronedarone was reported to attenuate left ventricular hypertrophy of mice. However, the molecular regulatory mechanism of dronedarone in MH is unclear.","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":"19 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140800762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beta Blockers in Contemporary Cardiology: Is It Better to Cast Them Out?","authors":"Javaid Ahmad Dar, John Roshan Jacob","doi":"10.4070/kcj.2023.0209","DOIUrl":"https://doi.org/10.4070/kcj.2023.0209","url":null,"abstract":"Beta blockers are one of the commonest prescription drugs in medicine and they have been thought to revolutionize the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) in the last century. In addition to HFrEF, they are prescribed for a variety of diseases in cardiology from hypertension to HF, angina, and stable coronary artery disease (CAD). The increased prescription of beta blockers in conditions like HF with preserved ejection fraction (HFpEF), and stable CAD may be doing more harm than good as per the data we have so far. The available data shows that beta blockers are associated with increased stroke risk and atrial fibrillation (AF) in hypertension and in patients with HFpEF, they have been associated with decreased exercise capacity. In patients with stable CAD and patients with myocardial infarction with normal systolic functions, beta blockers don't offer any mortality benefit. In this article, we critically review the common indications and the uses of beta blockers in patients with HFpEF, CAD, hypertension and AF and we propose that beta blockers are over-prescribed under the shadow of their beneficial effects in patients with HFrEF.","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":"240 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140800674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}