Klinische Padiatrie最新文献_第4页

A Rare Case of GABAA Receptor Autoimmune Encephalitis in a Six-Year-Old Girl Improved by an Early Combined Immunotherapy. 六岁女童患 GABAA 受体自身免疫性脑炎的罕见病例：早期联合免疫疗法使病情好转

IF 1.2 4区医学

Klinische Padiatrie Pub Date : 2024-08-06 DOI: 10.1055/a-2356-7437

Matthias Preusse, Svitlana Lisovets, Annikki Bertolini, Kevin Rostásy, Soeren Lutz

引用次数: 0

The Susceptibility of Escherichia Coli to Antibiotic Treatment for Pediatric Patients With Febrile Urinary Tract Infections in the Bratislava Region. 布拉迪斯拉发地区发热性尿路感染儿科患者大肠埃希菌对抗生素治疗的敏感性。

IF 1.2 4区医学

Klinische Padiatrie Pub Date : 2024-08-02 DOI: 10.1055/a-2356-7784

Barbora Pitekova, Patrik Konopásek, Miriama Babelova, Jakub Gecz, Kristina Hlasna, Jan Breza, Peter Barton, Jakub Zieg

{"title":"The Susceptibility of Escherichia Coli to Antibiotic Treatment for Pediatric Patients With Febrile Urinary Tract Infections in the Bratislava Region.","authors":"Barbora Pitekova, Patrik Konopásek, Miriama Babelova, Jakub Gecz, Kristina Hlasna, Jan Breza, Peter Barton, Jakub Zieg","doi":"10.1055/a-2356-7784","DOIUrl":"https://doi.org/10.1055/a-2356-7784","url":null,"abstract":"Urinary tract infections are one of the most common types of bacterial infections in childhood. Normally, empiric antibiotic therapy is given based on local antimicrobial susceptibility. We performed a retrospective study to evaluate bacterial resistance and clinical responses to antibiotics in childhood febrile urinary tract infections (fUTIs) in the Bratislava region of Slovakia. A total of 182 children with a fUTI were enrolled in our retrospective study. 84,07% of these fUTIs were caused by pathogenic Escherichia coli (E. coli). According to microbial antibiotic susceptibility tests, the most effective antibiotic agents were third-generation cephalosporins (susceptibility was observed in 92,16% (n=141) of the cases), followed by aminopenicillins with betalactamase inhibitor (susceptibility was observed in 84,97% (n=130) of the cases) and trimethoprim-sulfamethoxazole (susceptibility was observed in 79,74% (n=122) of the cases). In contrast, E. coli was susceptible to second-generation cephalosporins in just 3,92% (n=6). Patients treated with third-generation cephalosporins achieved a clinical response to therapy almost in all of the cases (95,7% (n=66)), whereas second-generation cephalosporins were associated with a clinical response to therapy in only 55,9% (n=33) of the cases. Third-generation cephalosporins and aminopenicillins with a betalactamase inhibitor appear to be the most suitable initial antibiotic therapies in pediatric patients with fUTIs. Following current guidelines alongside the regular assessment of regional microbial antibiotic susceptibilities should provide the best treatment management for children with fUTIs.","PeriodicalId":17846,"journal":{"name":"Klinische Padiatrie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141878997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enteroviral meningitis in children: Clinical and laboratory features with and without pleocytosis. 儿童肠道病毒脑膜炎：伴有或不伴有多核细胞增多的临床和实验室特征。

IF 1.2 4区医学

Klinische Padiatrie Pub Date : 2024-08-02 DOI: 10.1055/a-2345-3186

Zeynep Savaş Şen, Suna Ozdem, Rumeysa Yalcinkaya, Ruveyda Gumuser Cinni, Emine Polat, Meltem Polat, Ayse Kaman, Turkan Aydın Teke, Gonul Tanir, Fatma Nur Öz

{"title":"Enteroviral meningitis in children: Clinical and laboratory features with and without pleocytosis.","authors":"Zeynep Savaş Şen, Suna Ozdem, Rumeysa Yalcinkaya, Ruveyda Gumuser Cinni, Emine Polat, Meltem Polat, Ayse Kaman, Turkan Aydın Teke, Gonul Tanir, Fatma Nur Öz","doi":"10.1055/a-2345-3186","DOIUrl":"https://doi.org/10.1055/a-2345-3186","url":null,"abstract":"Background: Enteroviruses (EV) are most common causes of the etiologically known aseptic meningitis in children. EV can be detected with polymerase chain reaction (PCR) in cerebrospinal fluid (CSF) samples. We aimed to evaluate the clinical and laboratory characteristics of children diagnosed with PCR-confirmed EV meningitis in CSF samples.Patients: Patients aged 1 month to 17 years who underwent lumbar puncture (LP) with suspected meningitis and had CSF viral PCR and culture results between September 2012 and January 2021 at a tertiary care hospital in Turkey were included.Methods: Patients with no virus detected in CSF samples by PCR was comprised PCR-negative group. The EV PCR-positive patients were divided into two groups based on CSF pleocytosis as enteroviral meningitis (EVM) with CSF pleocytosis and EVM without CSF pleocytosis, and compared in terms of clinical and laboratory features.Results: 78 (38.2%) were EV PCR-positive, and 126 (61.8%) were PCR-negative. Pleocytosis was detected in 55 (70.5%) EV PCR-positive patients and 94 (74.6%) of PCR-negative patients. Convulsion was significantly frequent (p=0.017) in EV PCR-positive patients with no pleocytosis. Protein and lactate concentrations in CSF were significantly higher in EV PCR-positive patients with pleocytosis (p=0.048, p=0.001, respectively). Median hospital stay was significantly longer in PCR-negative group (p<0.001).Conclusion: Diagnosing EVM with PCR prevents long-term hospitalization, unnecessary antibiotic use and healthcare-related complications.","PeriodicalId":17846,"journal":{"name":"Klinische Padiatrie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141878995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-syndromic Congenital Sodium Diarrhea: A Novel Mutation in the SLC9A3 Gene. 非综合征先天性钠腹泻：SLC9A3 基因的新型突变

IF 1.2 4区医学

Klinische Padiatrie Pub Date : 2024-08-02 DOI: 10.1055/a-2346-9589

Ferda Ozbay Hosnut, Gulseren Sahin, Bulent Uyanik, Serdar Ceylaner, Meltem Akcaboy

引用次数: 0

[Interprofessional Team Training for Nursing Trainees and Medical Students in Pediatrics: Comparing Analog and Digital Formats]. [儿科护理培训生和医科学生的跨专业团队培训：模拟和数字格式的比较]。

IF 1.2 4区医学

Klinische Padiatrie Pub Date : 2024-07-03 DOI: 10.1055/a-2339-3826

Katharina Fleig, Petra Tiroke, Fabian Pittau, Urs Mücke

{"title":"[Interprofessional Team Training for Nursing Trainees and Medical Students in Pediatrics: Comparing Analog and Digital Formats].","authors":"Katharina Fleig, Petra Tiroke, Fabian Pittau, Urs Mücke","doi":"10.1055/a-2339-3826","DOIUrl":"https://doi.org/10.1055/a-2339-3826","url":null,"abstract":"Background: Pediatrics places highest demands on interprofessional teams. Although training and studies are evolving, interprofessional teaching units are regularly lacking in German-speaking countries. Analog and digitally convertible formats are rare.Method: Since 2018, a voluntary one-day team training named \"SICKO Junior\" for nursing trainees and medical students has been conducted regularly in analog and in the meantime digitally. Evaluation results on the analog and digital format are compared. The content of the one-day workshop is based on a concept for medical employees. Exemplary communication in the ward round is reflected in simulations, training on the simulator for lumbar punctures serves the change of perspective.Results: A total of 104 participants took part, 21 of them digital. The recommendation rate is 100%. All of the participants are convinced that the workshop has a positive impact on collaborative interprofessional work. There were no significant differences in the evaluation of the different workshop elements between the digital and analog trainings.Discussion: The present work sheds light on the positive influence independent of the digital/analogue form. The presentation forms a blueprint for dissemination. A curricular integration seems worthwhile.Conclusion Voluntary interprofessional team training for nursing trainees and medical students with a focus on communication and error culture is as popular in digital as in analog form. Future studies should prove the influence on competence development and safety culture.","PeriodicalId":17846,"journal":{"name":"Klinische Padiatrie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141498355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Massive Air Leak Syndrome During High Flow Oxygen Therapy and a Rare Complication: Pneumorrhachis. 高流量氧气治疗过程中的大量漏气综合征及罕见并发症：肺出血。

IF 1.2 4区医学

Klinische Padiatrie Pub Date : 2024-07-01 Epub Date: 2023-07-11 DOI: 10.1055/a-2041-2914

Aytaç Göktuğ, Songül Sönmez, Dinçel Eren, Özgür Çağlar, Yasemin Tasci Yildiz, Mutlu Uysal Yazici, Nilden Tuygun

引用次数: 0

Rare Case of Recurrent Salmonella Typhimurium Meningitis in a 55-day-old Infant: Importance of Immunodeficiency Susceptibility. 55 天婴儿复发性鼠伤寒沙门氏菌脑膜炎罕见病例：免疫缺陷易感性的重要性。

IF 1.2 4区医学

Klinische Padiatrie Pub Date : 2024-07-01 DOI: 10.1055/a-2348-0349

Selcuk Uzuner, Ozden Turel, Can Yilmaz Yozgat, Ufuk Erenberk, Deniz Çağdaş Ayvaz, Stephanie Boisson-Dupuis

引用次数: 0

A Retrospective Analysis of Risk Factors and Impact of Acute Kidney Injury in Critically Ill Children. 重症儿童急性肾损伤风险因素及影响的回顾性分析。

IF 1.2 4区医学

Klinische Padiatrie Pub Date : 2024-07-01 Epub Date: 2023-02-27 DOI: 10.1055/a-1996-1761

Kubra Celegen, Mehmet Celegen

{"title":"A Retrospective Analysis of Risk Factors and Impact of Acute Kidney Injury in Critically Ill Children.","authors":"Kubra Celegen, Mehmet Celegen","doi":"10.1055/a-1996-1761","DOIUrl":"10.1055/a-1996-1761","url":null,"abstract":"Background: Acute kidney injury (AKI) is a serious clinical condition in critically ill children and is associated with worse outcomes. A few pediatric studies focused on the risk factors of AKI. We aimed to identify the incidence, risk factors, and outcomes of AKI in the pediatric intensive care unit (PICU).Patients and methods: All the patients admitted to PICU over a period of 20 months were included. We compared both groups the risk factors between AKI and non-AKI.Results: A total of 63 patients (17.5%) of the 360 patients developed AKI during PICU stay. The presence of comorbidity, diagnosis of sepsis, increased PRISM III score, and positive renal angina index were found to be risk factors for AKI on admission. Thrombocytopenia, multiple organ failure syndrome, the requirement of mechanical ventilation, use of inotropic drugs, intravenous iodinated contrast media, and exposure to an increased number of nephrotoxic drugs were independent risk factors during the hospital stay. The patients with AKI had a lower renal function on discharge and had worse overall survival.Conclusions: AKI is prevalent and multifactorial in critically sick children. The risk factors of AKI may be present on admission and during the hospital stay. AKI is related to prolonged mechanical ventilation days, longer PICU stays, and a higher mortality rate. Based on the presented results early prediction of AKI and consequent modification of nephrotoxic medication may generate positive effects on the outcome of critically ill children.","PeriodicalId":17846,"journal":{"name":"Klinische Padiatrie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9342867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cornelia de Lange Syndrome Presenting as Hydrops Fetalis due to Intestinal Atresia. 因肠道闭锁而表现为胎儿水肿的科尼莉亚-德-兰格综合征。

IF 1.2 4区医学

Klinische Padiatrie Pub Date : 2024-07-01 Epub Date: 2023-07-21 DOI: 10.1055/a-2099-3386

Duran Yildiz, Ufuk Cakir, Dilek Kahvecioglu, Serdar Alan, Omer Erdeve, Begum Atasay, Saadet Arsan

引用次数: 0

The Derivation of Epigastric Motion to Assess Neonatal Breathing and Sleep: An Exploratory Study. 推导上腹部运动以评估新生儿呼吸和睡眠：一项探索性研究

IF 1.2 4区医学

Klinische Padiatrie Pub Date : 2024-07-01 Epub Date: 2023-09-06 DOI: 10.1055/a-2135-2163

Guido Stichtenoth, Niclas Knottnerus-Meyer, Jonas Helmstetter, Marco Maass, Egbert Herting

{"title":"The Derivation of Epigastric Motion to Assess Neonatal Breathing and Sleep: An Exploratory Study.","authors":"Guido Stichtenoth, Niclas Knottnerus-Meyer, Jonas Helmstetter, Marco Maass, Egbert Herting","doi":"10.1055/a-2135-2163","DOIUrl":"10.1055/a-2135-2163","url":null,"abstract":"Introduction: New non-medical monitors are offered for respiration monitoring of neonates. Epigastric motion during sleep was investigated by means of a wearable tracker in parallel to clinical monitoring.Cohort: 23 hospitalised neonates ready for discharge.Methods: A 3-axes-accelerometer and -gyroscope was placed in a standard epigastric position. Between two routine care rounds signals were recorded in parallel to monitoring of impedance pneumography (IP), ECG and pulse oximetry. Motion signals vs. time charts were evaluated using 10-min episodes and semiquantitatively assigned to breathing signal quality, regular breathing, periodic breathing and confounding artefacts. The results were compared with the impedance pneumographic data.Results: 26 recordings (mean duration: 210 min/infant) were conducted without bradycardia or apnea alarm. The gestational age at birth ranged 28.9 to 41.1 and at recording from 35.6 to 42.3 postmenstrual weeks. Motion patterns of quiet sleep with regular breathing, periodic breathing and active sleep with confounding body movements were found. The longitudinal and transversal gyroscope axes resulted in best signal quality. Periodic breathing was found in up to 80% of episodes and decreased inversely with gestational age showing significantly more periodic breathing in preterm infants. Respiration signals of the gyroscope vs. IP showed a low bias and highly variating frequencies.Conclusions: Standardized motion trackers may detect typical neonatal breathing and body-motion-patterns, that could help to classify neonatal sleep. Respiratory rates can only be determined during quiet sleep.","PeriodicalId":17846,"journal":{"name":"Klinische Padiatrie","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10169382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0