Klinische Padiatrie最新文献_第10页

[Hospital-based Home Care for Children with Cancer from the Parents̓ Point of View - A Qualitative Exploration of Family Members]. [从父母的角度看癌症儿童的医院家庭护理--家庭成员的定性研究]。

IF 1 4区医学

Klinische Padiatrie Pub Date : 2024-05-01 Epub Date: 2024-03-04 DOI: 10.1055/a-2246-2645

Ute Karbach, Sarah Krawiec, Stephan Remmert, Rebecca Toenne, Dirk Reinhardt, Dominik T Schneider, Thorsten Simon, Katharina Waack-Buchholz, Rebecca Kristiment

{"title":"[Hospital-based Home Care for Children with Cancer from the Parents̓ Point of View - A Qualitative Exploration of Family Members].","authors":"Ute Karbach, Sarah Krawiec, Stephan Remmert, Rebecca Toenne, Dirk Reinhardt, Dominik T Schneider, Thorsten Simon, Katharina Waack-Buchholz, Rebecca Kristiment","doi":"10.1055/a-2246-2645","DOIUrl":"10.1055/a-2246-2645","url":null,"abstract":"Background: About 2,200 children and adolescents in Germany per year are diagnosed with oncological diseases. Through now, there are almost no offers for home care services for these patients. There is a pilot program offering hospital-based home care for children and adolescents with cancer in Germany. The perspective of the parents will be researched by a qualitative exploring study.Patients: In this interview study parents from children with cancer will be interviewed.Method: A qualitative exploring interview study, seeking the subjective perspective from parents on the hospital-based home care for children with cancer. The sample was drawn criterion-guided. The interviews were transcribed verbatim and analysed using qualitative content analysis. For socio- demographic characteristics the participants respond to an online questionnaire.Results: Eleven women and three men aged between 30 and 60 years participated in the interviews. The average age of the ill children was 8.43 years. Five parents state that the children's illness did not lead to a reduction in working hours or to the termination of the employment relationship. Hospital-based home care results in subjectively perceived relief in everyday family life, especially in terms of time. Furthermore, a reduction in the psychological perception of stress is described.Discussion/conclusion: Due to the study design, the results presented here are to be regarded as indicative. In future studies the presented results should be supplemented by quantitative representative studies.","PeriodicalId":17846,"journal":{"name":"Klinische Padiatrie","volume":" ","pages":"165-172"},"PeriodicalIF":1.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140028334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tularemia In A 14-Year-Old Female Pediatric Patient - A Case Report. 一名 14 岁儿科女病人的土拉菌病--病例报告。

IF 1 4区医学

Klinische Padiatrie Pub Date : 2024-03-01 DOI: 10.1055/a-2250-5353

Charline Schmitt, Sabine Heine, Arne Simon, Annabelle Wagner

引用次数: 0

Intracranial Tuberculoma Developing During The Treatment Of A Case With Tuberculous Meningitis Caused By The Zoonotic Mycobacterium Caprae. 在治疗一例由人畜共通的 Caprae 分枝杆菌引起的结核性脑膜炎病例期间出现的颅内结核瘤。

IF 1 4区医学

Klinische Padiatrie Pub Date : 2024-02-06 DOI: 10.1055/a-2244-7061

Fatma Kılınc, Ümmühan Çay, Fatma Tuğba Çetin, Nisanur Tapac, Ozlem Ozgur Gundeslioglu, Derya Alabaz

引用次数: 0

Inpatient Rsv-Management 2016-2022: Epidemiology and Adherence to A Bronchiolitis Treatment Standard at a German University Children's Hospital. 2016-2022 年住院病人 Rsv 管理：德国一所大学儿童医院的流行病学和支气管炎治疗标准的遵守情况。

IF 1 4区医学

Klinische Padiatrie Pub Date : 2024-02-06 DOI: 10.1055/a-2218-5171

Solvej Heidtmann, Yeliz Baltaci, Sascha Meyer, Michael Zemlin, Rhoikos Furtwängler, Juergen Rissland, Arne Simon

{"title":"Inpatient Rsv-Management 2016-2022: Epidemiology and Adherence to A Bronchiolitis Treatment Standard at a German University Children's Hospital.","authors":"Solvej Heidtmann, Yeliz Baltaci, Sascha Meyer, Michael Zemlin, Rhoikos Furtwängler, Juergen Rissland, Arne Simon","doi":"10.1055/a-2218-5171","DOIUrl":"https://doi.org/10.1055/a-2218-5171","url":null,"abstract":"Background: This study analyzes the RSV season 2021/2022 in a referral children's hospital, compares the epidemiology and illness severity with RSV-infected inpatients from 2016 to 2020 and audits the adherence to our internal therapy standard for RSV bronchiolitis.Material and methods: Inpatients with rtPCR-confirmed RSV infection (Jan. 2016 to Jan. 2022).Results: The audit comprises 306 RSV inpatients, on average 50 hospitalizations per year; in 03/2020, a rapid RSV Season-Offset was observed. In the winter season 2020/2021, no patient with RSV was hospitalized. Beginning in July, we noticed a rapid increase of RSV-admissions (most cases in Sept./Oct, duration until Dec. 2021; n=53). In 2021-2022, a significant larger share needed PICU admission (9.4% vs 3.2%, p=0.040). Adherence to the internal guidance was low; only 11.8% (n=36) of all patients received supportive treatment without inhalative or systemic medications, 37% of all patients received antibiotics.Conclusions: This audit confirms the strong impact of public preventive measures directed against SARS-CoV-2 transmission on RSV epidemiology. Few weeks after easing public COVID-19 restrictions (summer 2021), RSV inpatient cases rapidly increased, lasting until Dec. 2021. The audit of bronchiolitis management revealed surprisingly low adherence to the internal guidance, despite a face-to-face educational session with the attending pediatricians in Oct. 2021. Low adherence resulted in an unnecessary exposure of RSV patients to systemic medications of questionable benefit including antibiotics.","PeriodicalId":17846,"journal":{"name":"Klinische Padiatrie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139697825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Mild Case of Jeune Syndrome Associated with a Recurrent Missense Variant in DYNC2H1: Confirmation of a Genotype-Phenotype Correlation. 与 DYNC2H1 的复发性错义变异有关的轻度 Jeune 综合征病例：基因型与表型相关性的确认。

IF 1 4区医学

Klinische Padiatrie Pub Date : 2024-02-01 Epub Date: 2024-01-15 DOI: 10.1055/a-2235-6201

Marc-Alexander Oestreich, Fabian Keller, Xenia Bovermann, Dominique Braun, Rike Schiller, Luigi Raio, Christiane Zweier, Carmen Casaulta, Jakob Usemann, André Kidszun, Mircea-Horia Popa-Todirenchi

引用次数: 0

Relapsing Polychondritis with Tracheobronchial Involvement: A Detailed Description of Two Pediatric Cases and Review of the Literature. 气管支气管受累的复发性多软骨炎：两例儿科病例的详细描述和文献综述。

IF 1 4区医学

Klinische Padiatrie Pub Date : 2024-02-01 Epub Date: 2024-01-15 DOI: 10.1055/a-2230-1521

Greta Winter, Tara Löffelmann, Shaakira Chaya, Hannah Kaiser, Nils Kristian Prenzler, Athanasia Warnecke, Martin Wetzke, Thorsten Derlin, Diane Renz, Thomas Stueber, Florian Länger, Katharina Schütz, Nicolaus Schwerk

引用次数: 0

Ten-year experience of whole lung lavage in pediatric Pulmonary Alveolar Proteinosis. 对小儿肺泡蛋白病进行全肺灌洗的十年经验

IF 1 4区医学

Klinische Padiatrie Pub Date : 2024-02-01 Epub Date: 2024-01-23 DOI: 10.1055/a-2194-3467

Katja Nickel, Katharina Schütz, Julia Carlens, Simon Grewendorf, Martin Wetzke, Oliver Keil, Nils Dennhardt, Vanessa Rigterink, Harald Köditz, Michael Sasse, Christine Happle, Christiane E Beck, Nicolaus Schwerk

{"title":"Ten-year experience of whole lung lavage in pediatric Pulmonary Alveolar Proteinosis.","authors":"Katja Nickel, Katharina Schütz, Julia Carlens, Simon Grewendorf, Martin Wetzke, Oliver Keil, Nils Dennhardt, Vanessa Rigterink, Harald Köditz, Michael Sasse, Christine Happle, Christiane E Beck, Nicolaus Schwerk","doi":"10.1055/a-2194-3467","DOIUrl":"10.1055/a-2194-3467","url":null,"abstract":"Background: Pulmonary Alveolar Proteinosis (PAP) is extremely rare and can be caused by hereditary dysfunction of the granulocyte macrophage colony-stimulating factor receptor (GM-CSF) receptor, autoantibodies against GM-CSF, or other diseases leading to alveolar macrophage (AM) dysfunction. This leads to protein accumulation in the lung and severe dyspnea and hypoxemia. Whole lung lavage (WLL) is the first line treatment strategy.Methods: Here, we present data from more than ten years of WLL practice in pediatric PAP. WLL performed by the use of a single lumen or double lumen tube (SLT vs. DLT) were compared for technical features, procedure time, and adverse events.Results: A total of n=57 procedures in six PAP patients between 3.5 and 14.3 years of age were performed. SLT based WLL in smaller children was associated with comparable rates of adverse events but with longer intervention times and postprocedural intensive care treatment when compared to DLT based procedures.Discussion: Our data shows that WLL is feasible even in small children. DLT based WLL seems to be more effective, and our data supports the notion that it should be considered as early as possible in pediatric PAP.Conclusion: WLL lavage is possible in small PAP patients but should performed in close interdisciplinary cooperation and with age appropriate protocols.","PeriodicalId":17846,"journal":{"name":"Klinische Padiatrie","volume":" ","pages":"64-72"},"PeriodicalIF":1.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10883753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139541193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

TB or not TB? Diagnostic Sensitivity, Specifity and Interobserver Agreement in the Radiological Diagnosis of Pulmonary Tuberculosis in Children. 肺结核与否？儿童肺结核放射诊断的敏感性、特异性和观察者之间的一致性

IF 1 4区医学

Klinische Padiatrie Pub Date : 2024-02-01 Epub Date: 2024-02-06 DOI: 10.1055/a-2230-6958

Folke Brinkmann, Jana Hofgrefe, Frank Ahrens, Jürgen Weidemann, Lars Daniel Berthold, Nicolaus Schwerk

{"title":"TB or not TB? Diagnostic Sensitivity, Specifity and Interobserver Agreement in the Radiological Diagnosis of Pulmonary Tuberculosis in Children.","authors":"Folke Brinkmann, Jana Hofgrefe, Frank Ahrens, Jürgen Weidemann, Lars Daniel Berthold, Nicolaus Schwerk","doi":"10.1055/a-2230-6958","DOIUrl":"10.1055/a-2230-6958","url":null,"abstract":"Background: The differentiation between latent tuberculosis infection (LTBI) and tuberculosis (TB) relies on radiological changes. Confirming the diagnosis remains a challenge because typical findings are often missing in children. This study evaluates diagnostic sensitivity, specifity and interobserver agreement on the radiological diagnosis of TB by chest-x-rays in accordance to professional specialization and work experience.Methods: Chest x-rays of 120 children with proven tuberculosis infection were independently evaluated by general radiologists, paediatric radiologists and paediatric pulmonologists. Results were compared to a reference diagnosis created by group of experienced paediatric radiologists and paediatric pulmonologists. Primary endpoints were diagnostic sensitivity and specificity and interobserver variability defined as Krippendorfs alpha of thesel groups compared to the reference diagnosis.Results: Of the 120 chest x-rays 33 (27,5%) were diagnosed as TB by the reference standard . Paediatric pulmonologist had the highest diagnostic sensitivity (90%) but were less specific (71%) whereas general radiologist were less sensitive (68%) but more secific (95%). The best diagnostic accuracy was achieved by pediatric radiologists with a diagnostic sensitivity of 77% and specificity 95% respectively.Conclusions: We demonstrated significant interobserver variability and relevant differences in sensitivity and specificity in the radiological diagnosis of TB between the groups. Paediatric radiologists showed the best diagnostic performance. As the diagnosis of pulmonary TB has significant therapeutic consequences for children they should be routinely involved in the diagnostic process.","PeriodicalId":17846,"journal":{"name":"Klinische Padiatrie","volume":" ","pages":"123-128"},"PeriodicalIF":1.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139697829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Pulmonary Alveolar Proteinosis and new therapeutic concepts. 更正：肺泡蛋白病和新的治疗概念。

IF 1.2 4区医学

Klinische Padiatrie Pub Date : 2024-02-01 Epub Date: 2024-05-15 DOI: 10.1055/a-2320-5286

Claudio Rodriguez Gonzalez, Hannah Schevel, Gesine Hansen, Nicolaus Schwerk, Nico Lachmann

引用次数: 0

Editorial. 社论

IF 1 4区医学

Klinische Padiatrie Pub Date : 2024-02-01 Epub Date: 2024-02-22 DOI: 10.1055/a-2241-9672

Anna Wiemers, Stefanie Dillenhöfer, Anne Schlegtendal

引用次数: 0