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IF 14.8 1区 医学
Kidney international Pub Date : 2025-04-18 DOI: 10.1016/S0085-2538(25)00239-X
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引用次数: 0
Progress, challenges, and pragmatic concessions in predicting relative risk of kidney survival in ARPKD 预测ARPKD肾脏生存相对风险的进展、挑战和实际让步
IF 14.8 1区 医学
Kidney international Pub Date : 2025-04-18 DOI: 10.1016/j.kint.2025.02.018
Derek K. Ng , Matthew B. Matheson , Erum A. Hartung
{"title":"Progress, challenges, and pragmatic concessions in predicting relative risk of kidney survival in ARPKD","authors":"Derek K. Ng ,&nbsp;Matthew B. Matheson ,&nbsp;Erum A. Hartung","doi":"10.1016/j.kint.2025.02.018","DOIUrl":"10.1016/j.kint.2025.02.018","url":null,"abstract":"<div><div>Autosomal recessive polycystic kidney disease is rare, with heterogeneous disease progression toward kidney failure. Risk stratification tools are needed to identify patients at higher risk of progression. Burgmaier <em>et al.</em> developed a relative risk score model in the international ARPKD registry for children older than 2 months of age without kidney failure. Their regression-based model included 5 predictors and yielded a simple prognostic score that classified “lower-risk” and “higher-risk” groups. Discrimination separating these 2 groups was good, but there are potential future opportunities for absolute risk prediction. We discuss considerations for the interpretation of relative risk scores and external validation of prediction models in rare diseases like autosomal recessive polycystic kidney disease.</div></div>","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 5","pages":"Pages 788-791"},"PeriodicalIF":14.8,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Executive summary of the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children KDIGO 2025儿童肾病综合征管理临床实践指南执行摘要
IF 14.8 1区 医学
Kidney international Pub Date : 2025-04-18 DOI: 10.1016/j.kint.2024.11.006
Jürgen Floege , Keisha L. Gibson , Marina Vivarelli , Adrian Liew , Jai Radhakrishnan , Ethan M. Balk , Craig E. Gordon , Gaelen Adam , Marcello Tonelli , Amy Earley , Brad H. Rovin
{"title":"Executive summary of the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children","authors":"Jürgen Floege ,&nbsp;Keisha L. Gibson ,&nbsp;Marina Vivarelli ,&nbsp;Adrian Liew ,&nbsp;Jai Radhakrishnan ,&nbsp;Ethan M. Balk ,&nbsp;Craig E. Gordon ,&nbsp;Gaelen Adam ,&nbsp;Marcello Tonelli ,&nbsp;Amy Earley ,&nbsp;Brad H. Rovin","doi":"10.1016/j.kint.2024.11.006","DOIUrl":"10.1016/j.kint.2024.11.006","url":null,"abstract":"<div><div>The Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for the Management of Glomerular Diseases was last updated and published in 2021. KDIGO continues to be committed to the nephrology community to provide periodic updates, based on new developments for each of the glomerular diseases. For children with nephrotic syndrome, the updated guideline now contains a treatment algorithm on when to perform a kidney biopsy and/or genetic testing and which immunosuppressive therapy to use in children with a complete response to glucocorticoids (steroid sensitive), who subsequently become infrequent or frequent relapsers or even steroid dependent. If a glucocorticoid-sparing agent must be considered after failure of an initial glucocorticoid therapy to induce remission, the choice among a calcineurin inhibitor, oral cyclophosphamide, levamisole, mycophenolate mofetil, and rituximab is a decision that requires consideration of patient-related issues such as resources, adherence, adverse effects, and patient preferences. Herein, an executive summary of the most important changes in the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children is provided as a quick reference.</div></div>","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 5","pages":"Pages 806-808"},"PeriodicalIF":14.8,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using donor-derived cell-free DNA in kidney transplant patients: this jury needs more evidence 在肾移植患者中使用供体来源的无细胞DNA：陪审团需要更多的证据
IF 14.8 1区 医学
Kidney international Pub Date : 2025-04-18 DOI: 10.1016/j.kint.2024.10.029
Nay Seif , Roy D. Bloom
{"title":"Using donor-derived cell-free DNA in kidney transplant patients: this jury needs more evidence","authors":"Nay Seif ,&nbsp;Roy D. Bloom","doi":"10.1016/j.kint.2024.10.029","DOIUrl":"10.1016/j.kint.2024.10.029","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 5","pages":"Pages 796-799"},"PeriodicalIF":14.8,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glomerular deposits of neuron-derived neurotrophic factor in a case of membranous nephropathy lacking syphilis signature 无梅毒特征的膜性肾病肾小球神经元源性神经营养因子沉积1例
IF 14.8 1区 医学
Kidney international Pub Date : 2025-04-18 DOI: 10.1016/j.kint.2025.01.034
Rayane Benyahia , Serigne Gueye , Magali Colombat , Dominique Chauveau
{"title":"Glomerular deposits of neuron-derived neurotrophic factor in a case of membranous nephropathy lacking syphilis signature","authors":"Rayane Benyahia ,&nbsp;Serigne Gueye ,&nbsp;Magali Colombat ,&nbsp;Dominique Chauveau","doi":"10.1016/j.kint.2025.01.034","DOIUrl":"10.1016/j.kint.2025.01.034","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 5","pages":"Pages 935-936"},"PeriodicalIF":14.8,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Case | A patient with multiple myeloma, heart failure, and nonresolving acute kidney injury 病例|一例多发性骨髓瘤，心力衰竭，急性肾损伤
IF 14.8 1区 医学
Kidney international Pub Date : 2025-04-18 DOI: 10.1016/j.kint.2025.01.027
Míriam Montero-Estopiñá , Desirée Catalán-García , Eduardo Cortés , Valentina M. Blanco-Fernández , Jordi Soler-Majoral , Gladys Ibarra Fernandez , Néstor Rodríguez-Chitiva , Javier Paúl-Martínez , Fredzzia Graterol Torres , Jordi Bover , Jordi Ara , Abhilash Koratala , Eduardo R. Argaiz , Faeq Husain-Syed , Gregorio Romero-González
{"title":"The Case | A patient with multiple myeloma, heart failure, and nonresolving acute kidney injury","authors":"Míriam Montero-Estopiñá ,&nbsp;Desirée Catalán-García ,&nbsp;Eduardo Cortés ,&nbsp;Valentina M. Blanco-Fernández ,&nbsp;Jordi Soler-Majoral ,&nbsp;Gladys Ibarra Fernandez ,&nbsp;Néstor Rodríguez-Chitiva ,&nbsp;Javier Paúl-Martínez ,&nbsp;Fredzzia Graterol Torres ,&nbsp;Jordi Bover ,&nbsp;Jordi Ara ,&nbsp;Abhilash Koratala ,&nbsp;Eduardo R. Argaiz ,&nbsp;Faeq Husain-Syed ,&nbsp;Gregorio Romero-González","doi":"10.1016/j.kint.2025.01.027","DOIUrl":"10.1016/j.kint.2025.01.027","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 5","pages":"Pages 947-948"},"PeriodicalIF":14.8,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Tolerogenic dendritic cells protect against acute kidney injury.” Kidney International 2023;104:492–507 “耐受性树突状细胞保护急性肾损伤”的勘误表。肾国际2023；104:492-507
IF 14.8 1区 医学
Kidney international Pub Date : 2025-04-18 DOI: 10.1016/j.kint.2025.02.001
Jennifer S.Y. Li , Harry Robertson , Katie Trinh , Arti M. Raghubar , Quan Nguyen , Nicholas Matigian , Ellis Patrick , Angus W. Thomson , Andrew J. Mallett , Natasha M. Rogers
{"title":"Corrigendum to “Tolerogenic dendritic cells protect against acute kidney injury.” Kidney International 2023;104:492–507","authors":"Jennifer S.Y. Li ,&nbsp;Harry Robertson ,&nbsp;Katie Trinh ,&nbsp;Arti M. Raghubar ,&nbsp;Quan Nguyen ,&nbsp;Nicholas Matigian ,&nbsp;Ellis Patrick ,&nbsp;Angus W. Thomson ,&nbsp;Andrew J. Mallett ,&nbsp;Natasha M. Rogers","doi":"10.1016/j.kint.2025.02.001","DOIUrl":"10.1016/j.kint.2025.02.001","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 5","pages":"Page 949"},"PeriodicalIF":14.8,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
journal club 杂志俱乐部
IF 14.8 1区 医学
Kidney international Pub Date : 2025-04-18 DOI: 10.1016/j.kint.2025.03.006
{"title":"journal club","authors":"","doi":"10.1016/j.kint.2025.03.006","DOIUrl":"10.1016/j.kint.2025.03.006","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 5","pages":"Pages 772-775"},"PeriodicalIF":14.8,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The authors reply 作者回答道
IF 14.8 1区 医学
Kidney international Pub Date : 2025-04-18 DOI: 10.1016/j.kint.2025.02.004
Marina Vivarelli , Carla M. Nester
{"title":"The authors reply","authors":"Marina Vivarelli ,&nbsp;Carla M. Nester","doi":"10.1016/j.kint.2025.02.004","DOIUrl":"10.1016/j.kint.2025.02.004","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 5","pages":"Page 939"},"PeriodicalIF":14.8,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thrombotic microangiopathy following scorpion envenomation 蝎子中毒后的血栓性微血管病
IF 14.8 1区 医学
Kidney international Pub Date : 2025-04-18 DOI: 10.1016/j.kint.2024.10.033
Anila Abraham Kurien , Praveen Revu
{"title":"Thrombotic microangiopathy following scorpion envenomation","authors":"Anila Abraham Kurien ,&nbsp;Praveen Revu","doi":"10.1016/j.kint.2024.10.033","DOIUrl":"10.1016/j.kint.2024.10.033","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 5","pages":"Page 944"},"PeriodicalIF":14.8,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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