{"title":"Is online hemodiafiltration a cost-effective alternative to conventional hemodialysis?","authors":"Kevin F. Erickson , James Fotheringham","doi":"10.1016/j.kint.2025.01.012","DOIUrl":"10.1016/j.kint.2025.01.012","url":null,"abstract":"<div><div>In this issue, Schouten <em>et al.</em> report findings from a cost-effectiveness analysis of hemodiafiltration versu<em>s</em> conventional high-flux hemodialysis using data from the Comparison of High-Dose Hemodiafiltration with High-Flux Hemodialysis (CONVINCE) trial. They found that the overall cost-effectiveness of hemodiafiltration is within the range of accepted willingness-to-pay thresholds in some countries, while near (but outside) the lower-bound thresholds of other countries. How decision-makers value treatment costs for additional years on dialysis and country-specific costs and willingness-to-pay thresholds influence the cost-effectiveness of hemodiafiltration.</div></div>","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 4","pages":"Pages 602-605"},"PeriodicalIF":14.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143645031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mark A. Brown , Barnaby D. Hole , Frank Brennan , Nandini Vallath , Sara N. Davison
{"title":"Kidney supportive care: every nephrologist’s business","authors":"Mark A. Brown , Barnaby D. Hole , Frank Brennan , Nandini Vallath , Sara N. Davison","doi":"10.1016/j.kint.2025.01.010","DOIUrl":"10.1016/j.kint.2025.01.010","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 4","pages":"Pages 582-586"},"PeriodicalIF":14.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RASSF1A loss in ccRCC: genomic instability and the role of chromosome 3p","authors":"Joseph Walton , Laurie Ailles","doi":"10.1016/j.kint.2025.01.016","DOIUrl":"10.1016/j.kint.2025.01.016","url":null,"abstract":"<div><div>Clear cell renal cell carcinoma is characterized by the loss of chromosome 3p, which includes several tumor suppressor genes (e.g., <em>VHL</em>, <em>PBRM1</em>, <em>SETD2</em>, and <em>BAP1</em>) as well as <em>RASSF1a,</em> a frequently inactivated gene in many cancers. This commentary highlights work by Catalano <em>et al.</em>, which explores the functional consequences of Ras association domain family 1, isoform A (RASSF1A) loss in kidney epithelial cells and calls for further research to investigate the impacts of 3p loss to uncover new therapeutic targets for clear cell renal cell carcinoma.</div></div>","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 4","pages":"Pages 599-602"},"PeriodicalIF":14.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143645030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dorann Bartebin , David Buob , Nicolas Veyrenche , Jacques Fourgeaud , Pierre Frange , Bénédicte Neven , Cyrielle Aveline , Benjamin Thoreau , Nicolas Gauthier , David Boutboul , Khalil El Karoui
{"title":"Kidney dysfunction and nephromegaly related to kidney Aichi virus infection","authors":"Dorann Bartebin , David Buob , Nicolas Veyrenche , Jacques Fourgeaud , Pierre Frange , Bénédicte Neven , Cyrielle Aveline , Benjamin Thoreau , Nicolas Gauthier , David Boutboul , Khalil El Karoui","doi":"10.1016/j.kint.2024.09.025","DOIUrl":"10.1016/j.kint.2024.09.025","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 4","pages":"Page 762"},"PeriodicalIF":14.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Uromodulin, neutrophils, and control of urinary tract infection","authors":"Marianne Harvent , Olivier Devuyst","doi":"10.1016/j.kint.2024.12.015","DOIUrl":"10.1016/j.kint.2024.12.015","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"107 4","pages":"Pages 593-595"},"PeriodicalIF":14.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}