Journal of Vector Borne Diseases最新文献_第6页

Aedes aegypti oviposition in urban communities in the Northern Chihuahuan Desert. 埃及伊蚊在奇瓦瓦沙漠北部城市社区的产卵情况。

IF 0.8 4区医学

Journal of Vector Borne Diseases Pub Date : 2024-10-01 Epub Date: 2024-11-26 DOI: 10.4103/JVBD.jvbd_70_24

Adam J Vera, Albert G Soliz, Antonio de la Mora-Covarrubias, Douglas M Watts

{"title":"Aedes aegypti oviposition in urban communities in the Northern Chihuahuan Desert.","authors":"Adam J Vera, Albert G Soliz, Antonio de la Mora-Covarrubias, Douglas M Watts","doi":"10.4103/JVBD.jvbd_70_24","DOIUrl":"10.4103/JVBD.jvbd_70_24","url":null,"abstract":"Background objectives: Aedes aegypti (Linnaeus) is the vector of multiple arboviruses, the most important being dengue viruses (DENV) that causes more than 90 million cases per year. The expanded range of Ae.aegypti into temperate climates has contributed to the increasing risk of DENV to new human populations. As an effort to better understand the ecology of Ae. aegypti in a temperate climate, larval surveillance was conducted to identify oviposition locations of this species from 2016-2018 in two nonincorporated communities located in El Paso, Texas and Ciudad Juarez, Chihuahua, Mexico.Methods: This survey was conducted inside and outside private residences examining any possible water holding containers to collect with a dipper, turkey baster, or Pasteur pipette. Larvae and pupae were transported to the laboratory and reared to adults for morphological identification. A total of 601 Ae. aegypti larvae were collected and reared to adults from 24 containers in the Sparks community. In contrast, a total of 68 Ae. aegypti were collected and reared to adults from seven containers in the Anapra community.Results: In both locations, the predominant container type that yielded immature mosquitoes were plastic buckets. Although the results were based on a small sample size, the finding provided a preliminary understanding of the oviposition sites of Ae. aegypti in two urban communities in a temperate climate region.Interpretation conclusion: The identification of oviposition sites can be used to develop and implement vector control strategies.","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"626-629"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141759506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methodological and interpretative considerations in the study of the first Kyasanur Forest disease outbreak in Goa, India. 印度果阿首次爆发的 Kyasanur 森林疾病研究中的方法和解释性考虑因素。

IF 0.8 4区医学

Journal of Vector Borne Diseases Pub Date : 2024-10-01 Epub Date: 2024-11-26 DOI: 10.4103/JVBD.jvbd_113_24

Basil Joy

引用次数: 0

Single jar for collecting and rearing mosquito life stages: An innovative prototype. 用于收集和饲养蚊子生命阶段的单个罐子：创新原型。

IF 0.8 4区医学

Journal of Vector Borne Diseases Pub Date : 2024-10-01 Epub Date: 2024-11-26 DOI: 10.4103/JVBD.jvbd_57_24

Neetu Kachhwaha

{"title":"Single jar for collecting and rearing mosquito life stages: An innovative prototype.","authors":"Neetu Kachhwaha","doi":"10.4103/JVBD.jvbd_57_24","DOIUrl":"10.4103/JVBD.jvbd_57_24","url":null,"abstract":"Background objectives: Mosquitoes vectors are the key threat that spread viruses, bacteria, nematodes, protozoans, and other infections responsible for the transmission of serious public health ailments including dengue, yellow fever, malaria, and chikungunya.Methods: To rear and cultivate mosquitoes at multiple stages of development (egg, larva, pupa, and adult) to be employed in various biomedical research, an innovative tool mosquito larva adult 2-in-1 rearing jar was designed and developed. The eggs/larvae or adults collected from the field or laboratory cultures can be released into the lower larvae or upper adult-rearing chamber so that they can find a suitable breeding place to oviposit or metamorphose into wrigglers and tumblers attaining the adult stage. Aedes, Anopheles, and Culex are three significant genera (Diptera: Culicidae) that were reared in experiments using this jar (Method I) in contrast to other conventional instruments available (Method II).Results: Results of one-way ANOVA showed that the prototype was compatible and competitive for rearing, as the data was non-significant when compared in both groups. However, throughout the trials, it was discovered that the prototype had a greater record of mean percentage of adult emergence (98.33), which supports the novelty of the instrument.Interpretation conclusion: This unique device eliminates the need for multiple tools, causes minimum bodily damage to stages during handling, can be used in both the lab and the field, is inexpensive, lightweight, portable, and requires single manpower to operate.","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"574-580"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141261292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Asymmetrical reproductive interference between Aedes aegypti and Aedes albopictus : Implications for coexistence. 埃及伊蚊与白纹伊蚊之间不对称的生殖干扰：对共存的影响。

IF 0.8 4区医学

Journal of Vector Borne Diseases Pub Date : 2024-10-01 Epub Date: 2024-11-26 DOI: 10.4103/JVBD.jvbd_40_24

Tanvir Hasan, Sadia Afrin, Afroza Sultana, Ashekul Islam

{"title":"Asymmetrical reproductive interference between Aedes aegypti and Aedes albopictus : Implications for coexistence.","authors":"Tanvir Hasan, Sadia Afrin, Afroza Sultana, Ashekul Islam","doi":"10.4103/JVBD.jvbd_40_24","DOIUrl":"10.4103/JVBD.jvbd_40_24","url":null,"abstract":"Background objectives: Aedes aegypti and Ae. albopictus are two sympatric mosquito species that compete with each other for resources when their breeding habitats overlap. This study examines what happens when sympatric Ae. aegypti and Ae. albopictus mosquitoes' mate with each other and other species by looking at insemination rates, fecundity, and hatchability rate.Methods: We performed controlled mating experiments in laboratory settings, assessing both conspecific and interspecific crosses. We measured insemination rates, egg numbers, and hatching success to examine the reproductive interference dynamics between these two distinct mosquito species.Results: In the context of conspecific mating, it was observed that both female Ae. aegypti and Ae. albopictus exhibited high insemination rates, with percentages 98% and 94%, respectively. However, interspecific mating exhibited interesting asymmetries as Ae. albopictus males achieved a notable insemination success rate of 28% when mating with Ae. aegypti females, while Ae. aegypti males achieved only an 8% insemination success with Ae. albopictus females. Additionally, females that mated with interspecific males had reduced production of viable eggs compared to conspecific mating. Most notably, interspecific mating resulted in the production of infertile eggs, while conspecific mating led to successful hatching.Interpretation conclusion: The study reveals that Ae. aegypti and Ae. albopictus can asymmetrically interfere with each other's reproduction, causing a 'satyr' effect. This understanding of interspecific competition and reproductive interference in these mosquito species could impact their coexistence in shared breeding habitats.","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"547-554"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141534671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The crucial role of immunoblots in distinguishing Lyme disease from tick-borne relapsing fever. 免疫图谱在区分莱姆病和蜱传复发性热病方面的关键作用。

IF 0.8 4区医学

Journal of Vector Borne Diseases Pub Date : 2024-10-01 Epub Date: 2024-11-26 DOI: 10.4103/JVBD.jvbd_62_24

Zahra Ali Haque, Muhammad Aqib Farooq Khan, Mahnoor Shahzad

{"title":"The crucial role of immunoblots in distinguishing Lyme disease from tick-borne relapsing fever.","authors":"Zahra Ali Haque, Muhammad Aqib Farooq Khan, Mahnoor Shahzad","doi":"10.4103/JVBD.jvbd_62_24","DOIUrl":"10.4103/JVBD.jvbd_62_24","url":null,"abstract":"Lyme disease (LD) and tick-bome relapsing fever (TBRF), both consequences of Borrelia burgdorferi infection, pose significant public health threats with overlapping symptomatic presentations. A previous study explores the potential of line immunoblots (IBs) as a transformative diagnostic tool for distinguishing between LD and TBRF. By employing strategically designed recombinant proteins on nitrocellulose membrane strips, IBs offer enhanced accuracy in identifying antibodies in patient samples. While serological assays for LD have seen advancements, the diagnostic landscape for TBRF lags behind, necessitating comprehensive diagnostic approaches capable of addressing both conditions. Immunoblots, with their ability to detect antibodies with exceptional precision, not only facilitate accurate diagnosis but also enable tailored patient treatment and monitoring of treatment response. The study underscores the importance of immunoblots in improving diagnostic accuracy and patient outcomes for tick- borne diseases. In conclusion, as research progresses in understanding LD and TBRF, immunoblots emerge not only as diagnostic tool but also as valuable resources for advancing research and refining patient treatment strategies.","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"630-631"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141902197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of in vitro and in vivo therapeutic activity of Tarantula cubensis extract (Theranekron®) on Leishmania major. 研究狼蛛提取物（Theranekron®）对大头利什曼原虫的体外和体内治疗活性。

IF 0.8 4区医学

Journal of Vector Borne Diseases Pub Date : 2024-10-01 Epub Date: 2024-11-26 DOI: 10.4103/JVBD.jvbd_55_24

Elif Akyol, Zübeyda Akın Polat

{"title":"Investigation of in vitro and in vivo therapeutic activity of Tarantula cubensis extract (Theranekron®) on Leishmania major.","authors":"Elif Akyol, Zübeyda Akın Polat","doi":"10.4103/JVBD.jvbd_55_24","DOIUrl":"10.4103/JVBD.jvbd_55_24","url":null,"abstract":"Background objectives: Cutaneous leishmaniasis (CL) is a vector-borne parasitic disease caused by several species of the protozoan parasite Leishmania. The need for new anti-leishmanial drugs for the treatment of CL is complicated by factors such as high cost, toxicity, potential for resistance and limited long-term use of existing anti-leishmanial drugs. The aim of this study was to investigate the therapeutic effect of Tarantula cubensis alcoholic extract (TCE), which has been shown to have wound-healing, anti-inflammatory, regenerative, resolving and epithelialising effects, on Leishmania major promastigotes in vitro and in vivo in an experimental mouse model of CL.Methods: The effect of TCE on L. major promastigotes in vitro was investigated after determining non-cytotoxic concentrations of TCE using the XTT method. To establish a CL model, L. major amastigotes were injected into the paws of BALB/c mice. Lesion size and histopathological evaluation were used to assess the effect of treatment.Results: TCE was found to be effective against L. major promastigotes at 24 h and 48 h at concentrations 250 μg/ mL, 125 μg/mL and 62.5 μg/mL ( P <0.05). TCE was found to be more effective than meglumine antimonate in treating CL in the experimentally induced CL model in BALB/c mice.Interpretation conclusion: The results suggest that TCE holds promising potential as a therapeutic agent for the treatment of CL. However, further extensive investigations are required to substantiate and expand our understanding in this area.","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"594-600"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141261170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of clinical and laboratory finding in the differential diagnosis of hantavirus and leptospirosis infections. 临床和实验室发现在汉坦病毒和钩端螺旋体感染的鉴别诊断中的作用。

IF 0.8 4区医学

Journal of Vector Borne Diseases Pub Date : 2024-10-01 Epub Date: 2024-11-26 DOI: 10.4103/JVBD.jvbd_54_24

Ahmet Melih Şahin, Sinan Çetin, İlknur Şenel, Tuğçegül Erdem-Çakır, Emsal Aydın, Meltem Arzu Yetkin

{"title":"The role of clinical and laboratory finding in the differential diagnosis of hantavirus and leptospirosis infections.","authors":"Ahmet Melih Şahin, Sinan Çetin, İlknur Şenel, Tuğçegül Erdem-Çakır, Emsal Aydın, Meltem Arzu Yetkin","doi":"10.4103/JVBD.jvbd_54_24","DOIUrl":"10.4103/JVBD.jvbd_54_24","url":null,"abstract":"Background objectives: Hantavirus and leptospirosis infections are zoonotic diseases with similar clinical and laboratory findings. The aim of this study is to identify the distinguishing features of these two diseases, for which a definitive diagnosis can take a long time.Methods: Between September 2021 and June 2023, a total of 45 patients who were admitted to our hospital and were diagnosed with hemorrhagic fever with renal syndrome (HFRS) or leptospirosis were retrospectively evaluated. Patients were compared in terms of demographic data, clinical, and laboratory parameters. The role of these variables in predicting HFRS or leptospirosis was investigated. The two diseases were compared with regard to outcomes. Receiver operating characteristics were employed for the calculation of cut-off values, sensitivity, specificity, and positive and negative predictive values for parameters showing significant differences. A statistical significance level of p<0.05 was considered.Results: Fifteen patients diagnosed with HFRS and thirty patients diagnosed with leptospirosis were included in the study. In both groups, hospital admissions were observed with non-specific and similar symptoms. There was no statistically significant difference observed between the two groups in terms of length of hospital stay, blood product transfusion, requirement for hemodialysis, intensive care unit admission, the rate of return to normal renal function and mortality. Elevated ferritin levels were statistically significant in favor of HFRS, while lymphopenia, elevated bilirubin, CRP, and ESR were statistically significant in favor of leptospirosis.Interpretation conclusion: The use of laboratory findings and clinical symptoms can aid in the challenging task of accurately diagnosing and using appropriate treatment for these two diseases.","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"601-606"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141759550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of data-driven machine learning models and their potential role in predicting dengue outbreak. 开发数据驱动的机器学习模型及其在预测登革热爆发中的潜在作用。

IF 0.8 4区医学

Journal of Vector Borne Diseases Pub Date : 2024-10-01 Epub Date: 2024-11-26 DOI: 10.4103/0972-9062.393976

Bushra Mazhar, Nazish Mazhar Ali, Farkhanda Manzoor, Muhammad Kamran Khan, Muhammad Nasir, Muhammad Ramzan

{"title":"Development of data-driven machine learning models and their potential role in predicting dengue outbreak.","authors":"Bushra Mazhar, Nazish Mazhar Ali, Farkhanda Manzoor, Muhammad Kamran Khan, Muhammad Nasir, Muhammad Ramzan","doi":"10.4103/0972-9062.393976","DOIUrl":"10.4103/0972-9062.393976","url":null,"abstract":"Dengue fever is one of the most widespread vector-borne viral infections in the world, resulting in increased socio-economic burden. WHO has reported that 2.5 billion people are infected with dengue fever across the world, resulting in high mortalities in tropical and subtropical regions. The current article endeavors to present an overview of predicting dengue outbreaks through data-based machine-learning models. This artificial intelligence model uses real world data such as dengue surveillance, climatic variables, and epidemiological data and combines big data with machine learning algorithms to forecast dengue. Monitoring and predicting dengue incidences has been significantly enhanced through innovative approaches. This involves gathering data on various climatic factors, including temperature, rainfall, relative humidity, and wind speed, along with monthly records of dengue cases. The study functions as an efficient warning system, enabling the anticipation of dengue outbreaks. This early warning system not only alerts communities but also aids relevant authorities in implementing crucial preventive measures.","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"503-514"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139491595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computational design, docking, and molecular dynamics simulation study of RNA helicase inhibitors of dengue virus. 登革热病毒 RNA 螺旋酶抑制剂的计算设计、对接和分子动力学模拟研究。

IF 0.8 4区医学

Journal of Vector Borne Diseases Pub Date : 2024-10-01 Epub Date: 2024-11-26 DOI: 10.4103/JVBD.jvbd_188_23

Raghunath Satpathy, Sonali Acharya, Rashmiranjan Behera

{"title":"Computational design, docking, and molecular dynamics simulation study of RNA helicase inhibitors of dengue virus.","authors":"Raghunath Satpathy, Sonali Acharya, Rashmiranjan Behera","doi":"10.4103/JVBD.jvbd_188_23","DOIUrl":"10.4103/JVBD.jvbd_188_23","url":null,"abstract":"Background objectives: RNA viruses are complex pathogens in terms of their genetic makeup, mutation frequency, and transmission modes. They contain the RNA helicase enzyme, which plays a crucial role in the viral genome replication process. This work aims to develop and screen a potential molecule that could function as a dengue virus (DENV) RNA helicase inhibitor.Methods: The present study was performed by taking 26 potential derivatives of gedunin phytochemicals from the PubChem database as ligands. The binding of the compounds was analyzed by in silico docking considering DENV RNA helicase enzyme as the receptor.Results: After a thorough analysis of the docking scores, toxicity, and physicochemical properties, the compound tetrahydrogedunin was obtained as the best. Based on tetrahydrogedunin molecular structure, 100 drug-like molecules were designed using the Data Warrior tool. After screening for drug-likeness and ADMET properties, derivative number 42 was considered as promising. Further comparative docking of derivative 42 and a standard inhibitor molecule ST-610 with DENV RNA helicase enzyme showed binding affinity of 10.0 kcal/mol and -9.6 kcal/mol, respectively. The favorable interaction between DENV RNA helicase and derivative 42 was further validated by 50 nanoseconds molecular dynamics simulation and MM-GBSA analysis.Interpretation conclusion: Since the antiviral activity of derivative 42 has not been reported till date, the compound was predicted as a novel therapeutic molecule that can act against the dengue virus (DENV) RNA helicase enzyme.","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"536-546"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140849091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of InBios Scrub Typhus Detect IgM Rapid Test in acute fever cases from Southwest and East India. 在印度西南部和东部的急性发热病例中评估 InBios 恙虫病检测 IgM 快速检测仪。

IF 0.8 4区医学

Journal of Vector Borne Diseases Pub Date : 2024-10-01 Epub Date: 2024-11-26 DOI: 10.4103/JVBD.jvbd_73_22

Madhura Punekar, Anup Jayaram, Prasad Varamballi, Dsa Oliver, Sasidharanpillai Sabeena

引用次数: 0