Hongjuan Zhu, Wanli Chu, Ming Zhang, Sanmai Xiao, Cheng Xu, Zhiyuan Shi
{"title":"Impact of pre-hospital delays on the prognosis of older patients with diabetic foot ulcers: a 10-year retrospective study.","authors":"Hongjuan Zhu, Wanli Chu, Ming Zhang, Sanmai Xiao, Cheng Xu, Zhiyuan Shi","doi":"10.12968/jowc.2023.0284","DOIUrl":"https://doi.org/10.12968/jowc.2023.0284","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the impact of pre-hospital delay on the prognosis of older patients with diabetic foot ulcers (DFUs).</p><p><strong>Method: </strong>In this 10-year retrospective study, enrolled patients were divided into three groups based on the number of days before admission to hospital: <7 days (Group 1); 7-14 days (Group 2); and >14 days (Group 3). Electronic medical data were gathered, including: independent variables (such as age, sex, body mass index, education level and duration of diabetes); and dependent variables (such as number of surgeries, therapeutic regimen, Wagner grade, white blood cell counts, length of hospital stay (LoS), outcomes and treatment costs).</p><p><strong>Results: </strong>A total of 288 patients were included in the study, 192 of whom were male, and the median age was 65 years. Of the studied participants, 27 arrived at the hospital within seven days, while 223 arrived after >14 days since the onset of their DFU. Significant differences were observed in the distribution of age (p=0.03) among the three groups, with the age of Group 1 lower than that of Group 3 (p=0.02). Significant differences in the distribution of number of surgeries (p=0.01), LoS (p=0.04), outcomes (p=0.04) and costs (p=0.03) were also observed among the three groups. Analyses showed that Group 1 LoS was lower than that of Group 2 (p=0.02); the number of surgeries in Group 1 was lower than that of Group 2 (p<0.01) and Group 3 (p<0.01); and Group 1 costs were lower than those of Group 2 (p=0.03) and Group 3 (p=0.03). A positive relationship was observed between pre-hospital delay and Wagner grade (0.122; p=0.04), and a positive relationship was observed between Wagner grade and LoS (0.181; p<0.01), outcomes (0.294; p<0.01), and costs (0.289; p<0.01).</p><p><strong>Conclusion: </strong>The findings of this study showed that longer pre-hospital delays adversely affected outcomes, such as extended hospital stays, increased numbers of surgeries and elevated hospitalisation expenses, in patients with DFUs. Age may be an underlying factor for this; further study with an increased sample size and comprehensive data is warranted.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup4","pages":"S4-S9"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case series 3.","authors":"Kavitha Sanmugam","doi":"10.12968/jowc.2025.34.Sup4c.S19","DOIUrl":"10.12968/jowc.2025.34.Sup4c.S19","url":null,"abstract":"<p><p>These two case studies describe the use of Octenisept<sup>®</sup> in diabetic foot ulcers at a community hospital in Singapore.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup4c","pages":"S19-S21"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Enming Yong, Xiaoli Zhu, Jiayi Weng, Marcus Jia Ming Ng, Yuqing Michal Khoo, Zhiwen Joseph Lo
{"title":"Role of therapeutic treatment with antiseptic solutions in the care of diabetic foot ulcers.","authors":"Enming Yong, Xiaoli Zhu, Jiayi Weng, Marcus Jia Ming Ng, Yuqing Michal Khoo, Zhiwen Joseph Lo","doi":"10.12968/jowc.2025.34.Sup4c.S4","DOIUrl":"10.12968/jowc.2025.34.Sup4c.S4","url":null,"abstract":"<p><strong>Background: </strong>Diabetic foot ulcers (DFUs) are a prevalent and severe complication of diabetes, leading to significant morbidity, impaired health-related quality of life (HRQoL) and economic burden on healthcare systems. The complexity of DFUs often results in prolonged healing and high recurrence rates. Effective management strategies are crucial for improving outcomes and reducing complications.</p><p><strong>Aim: </strong>This study aimed to review the efficacy of antiseptic solutions in the treatment and care of DFUs.</p><p><strong>Method: </strong>A literature analysis was conducted to review clinical studies and guidelines on the use and efficacy of antiseptic solutions, particularly Octenisept<sup>®</sup> (0.1% octenidine dihydrochloride and 2% 2-phenoxyethanol). The review focused on the antimicrobial properties, biofilm-disruption capabilities and wound healing outcomes associated with the use of antiseptic solutions in DFU management.</p><p><strong>Results: </strong>Antiseptic solutions have potential to reduce bioburden, disrupt biofilm and modulate healing. There is a need to balance antimicrobial clinical efficacy with tolerability and cytotoxicity. The use and choice of adjunctive antiseptic solutions must be tailored to the patient, as antimicrobial efficacy can vary for antiseptic solutions, particularly for hypochlorous solutions. It is important to use products according to their instructions, with consideration of minimum contact time to maximise clinical efficacy. Low-pressure irrigation is adjunctive, and concurrent wound-bed preparation, including debridement, frequent inspection, infection and moisture control, remain important.</p><p><strong>Conclusions: </strong>The therapeutic application of antiseptic solutions in DFU care presents a promising approach to enhancing wound healing and reducing infection risks. Integrating these solutions into standard wound care protocols could lower the incidence of complications, improve HRQoL and decrease the economic burden associated with diabetic foot disease. Further large-scale studies are recommended to validate these findings and refine guidelines for antiseptic use in DFU management.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup4c","pages":"S4-S13"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case series 2.","authors":"Luin Tongson","doi":"10.12968/jowc.2025.34.Sup4c.S16","DOIUrl":"10.12968/jowc.2025.34.Sup4c.S16","url":null,"abstract":"<p><p>These two case studies describe the use of Octenisept<sup>®</sup> in diabetic foot ulcers at a medical centre in the Philippines.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup4c","pages":"S16-S18"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chih-Yun Pai, Hunter Morera, Sudeep Sarkar, Yangxin Huang, Kimberly S Hall, Linda J Cowan, Matthew J Peterson, Dmitry Goldgof
{"title":"Automated pressure ulcer dimension measurements using a depth camera.","authors":"Chih-Yun Pai, Hunter Morera, Sudeep Sarkar, Yangxin Huang, Kimberly S Hall, Linda J Cowan, Matthew J Peterson, Dmitry Goldgof","doi":"10.12968/jowc.2021.0171","DOIUrl":"10.12968/jowc.2021.0171","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this research was to develop an automatic wound segmentation method for a pressure ulcer (PU) monitoring system (PrUMS) using a depth camera to provide automated, non-contact wound measurements.</p><p><strong>Method: </strong>The automatic wound segmentation method, which combines multiple convolutional neural network classifiers, was developed to segment the wound region to improve PrUMS accuracy and to avoid the biased decision from a single classifier. Measurements from PrUMS were compared with the standardised manual measurements (ground truth) of two clinically trained wound care nurses for each wound.</p><p><strong>Results: </strong>Compared to the average ground truth measurement (38×34×15mm), measurement errors for length, width and depth were 9.27mm, 5.89mm and 5.79mm, respectively, for the automatic segmentation method, and 4.72mm, 4.34mm, and 5.71mm, respectively, for the semi-automatic segmentation method. There were no significant differences between the segmentation methods and ground truth measurements for length and width; however, the depth measurement was significantly different (p<0.001) from the ground truth measurement.</p><p><strong>Conclusion: </strong>The novel PrUMS device used in this study provided objective, non-contact wound measurement and was demonstrated to be usable in clinical wound care practice. Images taken with a regular camera can improve the classifier's performance. With a dataset of 70 PUs for single and multiple (four images per PU) measurements, the differences between length and width measurements of the PrUMS and the manual measurement by nurses were not statistically significant (p>0.05). A statistical difference (p=0.04) was found between depth measurements obtained manually and with PrUMS, due to limitations of the depth camera within PrUMS, causing missing depth measurements for small wounds.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 3","pages":"205-214"},"PeriodicalIF":1.5,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rosa Di Micco, Letizia Santurro, Veronica Zuber, Maria Luisa Gasparri, Giovanni Cisternino, Pitoni Ludovica, Raffaele Ceccarino, Stefano Antonio Rottino, Ornella Forma, Oreste D Gentilini
{"title":"Implant infection after prepectoral breast reconstruction treated with negative pressure wound therapy and photobiomodulation: a case report.","authors":"Rosa Di Micco, Letizia Santurro, Veronica Zuber, Maria Luisa Gasparri, Giovanni Cisternino, Pitoni Ludovica, Raffaele Ceccarino, Stefano Antonio Rottino, Ornella Forma, Oreste D Gentilini","doi":"10.12968/jowc.2022.0097","DOIUrl":"10.12968/jowc.2022.0097","url":null,"abstract":"<p><p>Prepectoral breast reconstruction is a relatively new surgical technique that allows placement of the implant directly over the pectoralis major. It has benefits in terms of patient wellbeing, operative time, postoperative pain and recovery. However, in cases of infection, implant removal is often required and the patient is left with a flat chest. To the authors' knowledge, this is the first case of breast implant infection after breast reconstruction, successfully treated with a combination of both negative pressure wound therapy (NPWT) and photobiomodulation (PBM). A 32-year-old female patient with a BRCA2 mutation had undergone bilateral risk-reducing, nipple-sparing mastectomy for in situ ductal breast carcinoma followed by a prepectoral reconstruction. On the left side, the patient presented with dehiscence of 2.5cm with implant exposure 90 days after surgery. After an initial conservative approach, the patient's condition worsened, and she developed a larger dehiscence and a red breast. She was treated with implant removal. PBM of the cavity and the application of VeraFlo Therapy (3M, US) with a polyurethane-foam filling in the residual cavity were adopted. <i>Pseudomonas aeruginosa</i> was isolated and appropriate antibiotic therapy was started. Every 48-72 hours, she returned to the operating room for a washout, PBM, microbiological swabs, foam exchange and continuing NPWT. After 21 days of this approach and two consecutive negative swabs, the patient underwent breast reconstruction with a subpectoral expander. After six months, a definitive implant of the same size as the contralateral one was positioned. The cosmetic result was good and patient satisfaction was high. The combination of NPWT and PBM may represent a good solution in case of breast implant infection after prepectoral reconstruction with benefits in terms of surgical outcome, patient satisfaction and postoperative quality of life.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 3","pages":"180-186"},"PeriodicalIF":1.5,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gustavo E Prezzavento, Lucila M Olivera Whyte, Rodrigo N Juárez Calvi, Juan A Rodríguez, Philippe Taupin
{"title":"Use of cadaveric skin allograft and Integra Dermal Regeneration Template to manage deep lower limb injuries.","authors":"Gustavo E Prezzavento, Lucila M Olivera Whyte, Rodrigo N Juárez Calvi, Juan A Rodríguez, Philippe Taupin","doi":"10.12968/jowc.2023.0230","DOIUrl":"10.12968/jowc.2023.0230","url":null,"abstract":"<p><strong>Objective: </strong>In full-thickness wounds, it is necessary to have an appropriate dermal replacement because dermal tissue does not regenerate into normal dermis after injury. The use of a dermal matrix underneath a skin graft during the healing process provides a scaffold that supports tissue growth, resulting in improvement of cosmesis and functional outcomes. The management of large wounds with deep skin impairment using a combination of dermal matrices has not been exhaustively studied. The objective of this study was to evaluate the results of managing lower limb trauma, with deep skin impairment, by combining the use of dermal matrices in stages.</p><p><strong>Method: </strong>This was a retrospective study of patients with lower limb trauma managed using a combination of cadaveric skin and Integra Dermal Regeneration Template (IDRT; Integra LifeSciences Corp., US) in stages, followed by an autologous skin graft, in the Hospital Aleman, Buenos Aires, Argentina from 2014-2021. Cosmesis was evaluated with the Vancouver Scar Scale (VSS) and Patient and Observer Scar Assessment Scale (POSAS). Functional outcomes were assessed one year after surgery.</p><p><strong>Results: </strong>In total, five patients were treated. The average affected body surface area was 11.2%. The average cadaveric skin, IDRT and skin autograft take rates were 98.4%, 98.4% and 99%, respectively. Upon follow-up, six months after surgery, the mean VSS was 3.2 and the mean POSAS was 27.8. After 12 months, the mean VSS was 2.6 and the mean POSAS was 22.6. In addition, no depression of the covered surfaces was observed. All patients recovered full articular function and movement after physical therapy.</p><p><strong>Conclusion: </strong>All patients presented full wound coverage with satisfactory cosmesis and functional outcomes. The combination of the use of cadaveric skin and IDRT consecutively in the same wound bed provides promising results for the management of lower limb trauma wounds with deep skin impairment.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 3","pages":"239-248"},"PeriodicalIF":1.5,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multidisciplinary approach to squamous cell carcinoma originating in hidradenitis suppurativa lesions: a case report.","authors":"Huining Wang, Zumei Song, Dongyun Xia, Qian Tang, Ling Wu, Lili Yu, Xiaoling Sun","doi":"10.12968/jowc.2023.0200","DOIUrl":"10.12968/jowc.2023.0200","url":null,"abstract":"<p><p>Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory skin disease, and squamous cell carcinoma (SCC) is a rare complication of longstanding HS. In this case report, we describe the clinical management of a 30-year-old male patient with HS, with an eight-year history of a recurrent abscess and a nonhealing ulcer-like wound on his right buttock. The patient was also diagnosed with SCC originating from HS. A multidisciplinary team was established, comprising an oncologist, a plastic surgeon and two enterostomal therapists, to administer various treatments including chemotherapy, wound care, and surgical removal of lesions. The wound completely healed 201 days later, without any recurrence observed during follow-up.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 3","pages":"196-199"},"PeriodicalIF":1.5,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}